Mishonga inorwisa mabhakitiriya yeFluoroquinolone: ​​Ngatizivei nezvengozi nemigumisiro yayo

Pamwe wakanyorerwa mushonga wekuuraya utachiona kana waenda kuna chiremba. Mimwe yacho yakasimba uye inogona kurapa hutachiona nekukurumidza. Asi waizviziva here kuti kune mimwe mishonga inorwisa mabhakitiriya yakasimba inogona kuva nemigumisiro yakakomba? Fluoroquinolones imhando yemishonga inoshandiswa chete muzviitiko zvakakosha. Nhasi, tichataura nezvezvinhu zvese nenzira iri nyore uye yakajeka.

Chii chinonzi fluoroquinolones idzi?

Zvichitaurwa zviri nyore, aya iboka remishonga inorwisa mabhakitiriya inoshandiswa kurapa kana kudzivirira mamwe mabhakitiriya. Kunyangwe yakawanikwa muma1960, vanachiremba vakatanga kuishandisa zvakanyanya muma1970 nema1980. Panguva iyoyo, mishonga iyi yaive yakakurumbira zvikuru. Yaishanda zvikuru mukurapa hutachiona hwakasiyana-siyana, kubva kuhutachiona hwemudumbu kusvika kumabayo. Yaive nyore kuinwa sepiritsi kamwe chete kana kaviri pazuva, zvichiita kuti ive nyore kuinwa. Yaidiwa zvikuru pakati pevanachiremba nekuti yaipa zororo nekukurumidza kunyangwe mamwe maantibiotics aisashanda. Zvisinei, dambudziko raive rekuti vamwe vanhu vakatanga kusangana nemigumisiro yakakomba kubva mumishonga iyi. Zvakare, nekuti yaishandiswa zvisina kufanira pachirwere chega chega, mamwe mabhakitiriya akatanga kuramba mishonga iyi (antibiotic resistance).

Mushonga uyu unoshanda sei?

Funga nezvebhakitiriya semuchina wekukopa. Inoramba ichigadzira makopi ayo, izvo zvinowedzera huwandu hwehutachiona mumiviri yedu. Kuti igadzire makopi aya, bhakitiriya inofanira kutambanudza kodhi yayo yemajini, kureva, DNA yayo. Maenzymes akakosha anobatsira kutambanudza DNA iyi. Mafluoroquinolones anomisa maenzymes anotambanudza DNA. Ipapo mabhakitiriya haagone kugadzira makopi, kureva kuti, haagone kubereka. Aya ndiwo maitiro emishonga iyi kudzora kupararira kwehutachiona.

Ndezvipi zvirwere zvinoshandiswa nefluoroquinolones?

Kutanga, ngatitarisei hutachiona hunowanzo shandiswa mushonga uyu. Kazhinji, haukurudzirwi kune zvinotevera zvinogona kurapwa nemamwe maantibiotic ari nyore:

• Sinusitis inorwadza zvikuru
• Bronchitis yakaoma (bronchitis yakaoma)
• Utachiona hwemunzira weti huri nyore (UTIs)

Heano mamwe mamiriro ezvinhu ayo chiremba anogona kunyora mushonga uyu:

• Matambudziko akaoma emunzira yeweti (UTIs)
• Chirwere chemabayo
• Utachiona hweprostate (Prostatitis)
• Manyoka anokonzerwa nemamwe mabhakitiriya
• Matambudziko akakomba apo utachiona hunopinda muropa, senge sepsis

Vanachiremba vemazino vanogonawo kuvakurudzira kune mamwe hutachiona hwemazino. Anoshandiswawo kune vanhu vane allergies kune mamwe ma antibiotic kana kana pasina mamwe masarudzo.

Mishonga ipi iri muboka refluoroquinolone?

Ungave uchiziva rimwe remazita aya. Aya ndiwo marudzi anonyanya kushandiswa efluoroquinolones. Izvi zvinouya muchimiro chemapiritsi, jekiseni remutsinga, madonhwe emunzeve, uye madonhwe emaziso.

Ndeipi migumisiro yakaipa yemishonga iyi?

Ichi ndicho chikamu chakakosha chechinyorwa chino. Havasi vese vanowana migumisiro yakaipa kubva ku fluoroquinolones. Zvisinei, kune vamwe vanhu, migumisiro yakaipa inogona kukonzera kukuvara kusingaperi. Saka zvakakosha kuziva izvi. Mimwe migumisiro inogona kuoneka mukati memaawa ekutanga mushonga. Mimwe inogona kuoneka mavhiki kana kunyange mwedzi mushure mekumira mushonga. Mimwe yemigumisiro yakaipa uye yakajairika ndeiyi:

• Matambudziko etendon: Tendon, kunyanya tendon yeAchilles iri kumashure kwechitsitsinho, inogona kuzvimba, kurwadza, kana kutotsemuka.
• Kukuvadzwa kwetsinga: Izvi zvinonzi peripheral neuropathy. Zviratidzo zvinogona kusanganisira kusanzwa, kukwenya, uye kunzwa kukwenya mumakumbo. Izvi dzimwe nguva zvinogona kuva zvechigarire.
• Matambudziko epfungwa: Kuzvidya mwoyo, kusagadzikana, kuvhiringidzika, kuora mwoyo, kuona zvinhu zvisipo, uye kunyange kufunga kuzviuraya zvinogona kuitika.
• Kukuvara kweaorta: Ichi chirwere chisingawanzoitiki asi chine njodzi zvikuru. Chinogona kukonzera kubvaruka kana kutsemuka kweaorta (aortic dissection).
• Kuchinja kwehuwandu hweshuga muropa: Huwandu hweshuga muropa hunogona kudzikira zvakanyanya kana kukwira kune vane chirwere cheshuga nevanhu vane hutano hwakanaka.
• Kune varwere vane myasthenia gravis: Kushaya simba kwetsandanyama kunogona kuwedzera kune vanhu vane chirwere ichi.

Unoita sei kana ukaona chiratidzo chakadai?

Kana ukaona chimwe chezviratidzo zvinotevera paunenge uchitora fluoroquinolone, rega kutora mushonga wacho wofonera chiremba wako nekukasika. Kana uchirwadziwa zvakanyanya kana kuti uchinetseka kufema, enda kuchipatara nekukurumidza.

• Kurwadziwa kamwe kamwe, kuzvimba, kana kuomarara kwematendo, majoini, kana tsandanyama.
• Kunzwa kusanzwa zvakanaka, kukwenya, kana kunzwa kukambaira mumakumbo.
• Kunetseka, kuvhiringidzika, kana kuchinja kwemamiriro epfungwa.
• Kunzwa dzungu kana kurova kwemoyo zvisina kurongeka.
• Manyoka ane kurwadziwa kwakanyanya mudumbu.

Mibvunzo Inowanzo bvunzwa (Mibvunzo Inowanzo bvunzwa)

1. Ma fluoroquinolones akarambidzwa here?

Kwete. Mishonga iyi ichiri kushandiswa. Asi ikozvino inokurudzirwa chete kune hutachiona hwakakomba uye hwakaoma, kwete hutachiona huri nyore. Zvakare, isarudzo yakakosha kune vanhu vane allergies kune mamwe maantibiotic.

2. Bactrim mushonga we fluoroquinolone here?

Kwete. Bactrim musanganiswa wemishonga miviri yakasiyana inorwisa mabhakitiriya (sulfamethoxazole netrimethoprim). Haisi yerudzi rwefluoroquinolone.

3. Amoxicillin ifluoroquinolone here?

Kwete. Amoxicillin mushonga unorwisa mabhakitiriya uri muboka repenicillin. Hausi fluoroquinolone. Fluoroquinolones, mishonga inorwisa mabhakitiriya, Ciprofloxacin, Levofloxacin, migumisiro yakaipa, hutachiona hwebhakitiriya, migumisiro yakaipa yemishonga inorwisa mabhakitiriya