Pamwe wakambonzwa nezve "mishonga yesulfa." Pamwe chiremba akakupa kirimu yekuisa paganda rako ndokuti, "Uyu mushonga wesulfa." Chii chinonzi sulfonamides? Ingori mishonga inorwisa mabhakitiriya here? Kwete, nyaya yacho yakareba kupfuura ipapo. Ngatitaurei nezvepfungwa iyi nhasi.
Zvichitaurwa zviri nyore, chii chinonzi sulfonamides idzi?
MaSulfonamides imhando yemishonga inogadzirwa mumarabhoritari. Haisi yemuzvarirwo. Mishonga yese iri mukirasi iyi yemishonga ine chinhu chinonzi "sulfur" muchimiro chayo chemakemikari. Ndosaka ichinzi "sulfonamides."
Zvino ngationei kuti izvi zvinoshanda sei. Kunyanya kana zvikapihwa kuhutachiona hwemabhakitiriya , zvinoitwa nemishonga iyi ndeyekumisa mabhakitiriya kugadzira chimwe chinhu chinonzi " folate " chaanoda. Tinozivawo kuti folate ivhitamini B9 . Ingofungai, ichi chinovaka muviri chinonzi folate chakakosha kuti mabhakitiriya ararame uye apararire. Saka kana mishonga ye sulfonamide ikapinda mumuviri, inomira mabhakitiriya kugadzira folate iyi. Zvakafanana nekushaya nzara usina chikafu, mabhakitiriya anoshaya simba zvishoma nezvishoma ofa.
"Saka hapana dambudziko here pamiviri yedu?" ungafunga kudaro. Kwete. Nekuti isu, kureva vanhu, tinowana folate inodiwa nemiviri yedu kubva muzvikafu zvatinodya. Hatigadziri folate mumiviri yedu. Saka mushonga uyu hauwanzokanganisa masero ari mumiviri yedu nenzira iyoyo.
Penicillin isati yawanikwa, muma1930, sulfonamides yaive imwe yemishonga yakanakisa iripo yekurapa hutachiona hwemabhakitiriya. Panguva iyoyo , mishonga iyi yakabatsira kuderedza huwandu hwevakafa nezvirwere zvinotapukira zvakanyanya. Asi nhasi, haingoshandiswi chete pahutachiona hwemabhakitiriya. Mishonga iri mukirasi iyi inoshandiswa kune zvimwe zvirwere zvakawanda.
Ndezvipi zvirwere zvinoshandiswa ne sulfonamides?
Kare, dzainyanya kushandiswa kurapa nekudzivirira hutachiona hwemabhakitiriya. Asi nhasi, mhando iyi yemishonga yashanduka zvakanyanya. Sulfonamides inoshandiswa kurapa zvirwere zvakasiyana-siyana, zvinosanganisira chirwere cheshuga cherudzi rwechipiri, BP, hutachiona hweHIV, uye melanoma, rudzi rwekenza yeganda.
Ngationei kuti mimwe mishonga iri muchikamu ichi ndeipi uye kuti inoshandiswa pazvirwere zvipi. Kuti zvive nyore, tichaipatsanura kuita zvikamu zviviri.
1. Sulfonamides inoshandiswa semishonga inorwisa mabhakitiriya
Iyi mishonga inonyanya kupihwa yekurapa hutachiona hwemabhakitiriya.
| Mhando dzemishonga inorwisa mabhakitiriya: sulfonamides |
|---|
| Mafenide (Sulfamylon®) |
| Sulfadiazene (Silvadene® kana Thermazene®) – (inoshandiswa zvakanyanya pakutsva) |
| Sulfamethizole |
| Sulfisoxazole |
| Sulfasalazine (Azulfidine®) – (Inoshandiswawo pakurapa chirwere chemudumbu chinonzi ulcerative colitis) |
| Sulfadoxine – (inoshandiswa kurapa malaria) |
2. Mishonga isingashandisi mishonga inorwisa mabhakitiriya inonzi sulfonamides
Iyi haisi mishonga inouraya mabhakitiriya. Inoshandiswa kurapa zvimwe zvirwere zvakawanda. Rondedzero iyi yakareba zvishoma, asi inokupa pfungwa yehukuru hwemhando iyi yemishonga.
| Zita reMushonga | Mashandisirwo |
|---|---|
| Acetohexamide, Chlorpropamide, Tolazamide, Tolbutamide | Chirwere cheshuga cherudzi rwechipiri |
| Furosemide (Lasix®), Bumetanide, Torsemide, Chlorthalidone, Hydrochlorothiazide, Indapamide | Mishonga inobvisa ropa inoshandiswa kurapa kuzvimba kunokonzerwa neBP yakakwira uye kutadza kushanda zvakanaka kwemoyo. |
| Celecoxib (Celebrex®) | Marwadzo emapfundo uye kuzvimba kwakadai searthritis. |
| Darunavir (Prezista®) | Mushonga wekudzivirira utachiona hweHIV. |
| Sumatriptan (Imitrex®) | Kune misoro ine migraine. |
| Sildenafil (Viagra®, Revatio®) | Kusashanda zvakanaka kwenhengo dzemudumbu uye BP yemapapu. |
| Tamsulosin (Flomax®) | Kune matambudziko ekuita weti anokonzerwa nekukura kweprostate gland (benign prostatic hyperplasia). |
| Zonisamide (Zonegran®) | Kubatwa nepfari kunokonzerwa nepfari. |
Zvinokwanisika here kuva ne allergies kune sulfonamides?
Ehe, unogona. Pamwe wakambonzwa vanhu vachiti, "Ndine allergy kumishonga yesulfa." Pakati pe3% ne8% yevanhu pasi rose vane allergy kumhando yemishonga yesulfa. Asi izvi zvakafanana nekusawirirana nepenicillin.
Chinhu chakakosha ndechekuti: kungoti wakamborwara nemushonga mumwe chete we sulfonamide hazvirevi kuti une allergy kune mimwe mishonga yese iri mukirasi iyi. Izvi ndizvo zvinogamuchirwa navanachiremba.
Saka, kana wakambova nechirwere che sulfonamide, iva nechokwadi chekuudza chiremba wako usati watanga mushonga mutsva. Iye achakwanisa kukurudzira mushonga wakakunakira.
Ndezvipi zvakaipa zvemhando iyi yemushonga?
Kufanana nemushonga upi zvawo, sulfonamides inogona kuva nezvimwe zvayakaipira uye migumisiro yakaipa. Zvikuru ndeizvi:
- Kusashanda kwebhakitiriya: Kana ukashandisa mushonga mumwe chete kwenguva yakareba, mamwe mabhakitiriya anoramba kushanda nemushonga iwoyo. Izvi zvinoreva kuti mushonga wacho hauchashandi pabhakitiriya idzodzo. Izvi zvinogonawo kuitika nesulfonamides.
- Kurasikirwa nemhedzisiro pamamwe mabhakitiriya: Mamwe marudzi emabhakitiriya anoramba mishonga iyi.
- Migumisiro yakaipa: Izvi hazviwanzoitiki , asi vamwe vanhu vanogona kusangana nezvirwere zvakakomba zveganda zvakaita seStevens -Johnson syndrome uye chepfu epidermal necrolysis .
Migumisiro iyi inogona kusiyana zvikuru kubva kumunhu kusvika kumunhu uye kubva kumishonga kusvika kumishonga. Saka, chiremba wako ndiye anonyanya kukupa ruzivo nezvemushonga waunorayirwa, mabhenefiti awo uye njodzi dzawo. Mubvunze nezvazvo.
Ko Bactrim™ isulfonamide zvakare here?
Ehe, muchikamu. Bactrim™ ine sulfamethizole, rudzi rwe sulfonamide. Pamusoro pezvo, inewo mumwe mushonga unonzi trimethoprim. Zvose izvi zvinoshanda pamwe chete.
Celebrex® isulfonamide zvakare here?
Ehe. Celecoxib (inowanzozivikanwa nezita rekuti Celebrex®), iyo inoshandiswa kurapa marwadzo earthritis, isulfonamide zvakare.
Mushonga uyu unogona kukonzera makristaro muweti here?
Ehe, mimwe mishonga yesulfa inogona kukonzera makristaro muweti. Zvisinei, izvi hazviwanzoitika. Chiremba wako achakuudza kana mushonga wauri kutora ungangokonzera izvi uye zvaunogona kuita kuti uzvidzivirire (semuenzaniso, inwa mvura yakawanda).
Mharidzo Yekuenda Nayo Kumba
- Mishonga yeSulfonamides haisi mishonga inorwisa mabhakitiriya chete, asi mishonga yakawanda inoshandiswa kurapa zvirwere zvakasiyana-siyana.
- Rudzi urwu rwemishonga runoshandiswa pazvirwere zvakawanda, kubva pakutapukirwa nemabhakitiriya kusvika kuchirwere cheshuga, BP, uye migraine.
- Kurwara kunogona kuitika kumishonga yesulfa. Zvisinei, kuva neallergies kune imwe mhando hazvirevi kuti uchava neallergies kumishonga yese iri mukirasi iyoyo.
- Usati watanga chero mushonga mutsva, iva nechokwadi chekuudza chiremba wako nezvezvimwe zvirwere zvaunazvo uye chero allergies yemishonga yawaimbova nayo.
Sulfonamides, mishonga yesulfa, sulfonamides, mishonga inorwisa mabhakitiriya, allergy yemishonga, Stevens-Johnson syndrome, Bactrim, Celebrex, Lasix
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