Unoziva here nezvematumbu emudumbu (GI NETs) anogona kukura mudumbu rako?

Dzimwe nguva unonzwa kurwadziwa mudumbu, kuzvimba, kana zvimwe zviratidzo zvinoita sekunge zviri kuuya nguva dzese here? Kana kuti unodzikira huremu pasina chikonzero chakajeka here? Kunyange zvazvo izvi zvichigona kuva zviratidzo zvezvirwere zvakajairika, panogona kunge paine chirwere chisingawanzoitika chaunofanira kuziva. Nhasi tichataura nezvechimwe chirwere chakadaro. Chinonzi Gastrointestinal Neuroendocrine Tumors , kana kuti GI NETs muchidimbu. Usazvidya mwoyo, tichataura nezvazvo zviri nyore.

Ndezvipi zvirwere zvemudumbu zvinonzi neuroendocrine bundu (GI NETs)?

Zvichitaurwa zviri nyore, maGI NET rudzi rwegomarara rusingawanzoitiki runokura mumasero e neuroendocrine ari mudumbu rako. Iye zvino ungave uchishamisika kuti masero e neuroendocrine chii. Aya imhando yakakosha yemasero anobatanidza sisitimu yedu yetsinga ne endocrine system. Akaita senzvimbo diki dzemashoko. Masero aya anowanikwa munzvimbo dzakawanda mumiviri yedu, kusanganisira sisitimu yekugaya.

Nzira yako yekugaya chikafu inenge yakaita sechubhu refu, inogaya chikafu chatinodya, inonwisa zvinovaka muviri, uye inobvisa tsvina. Matumbu aya e'GI NET' (aimbonzi 'carcinoid tumors') anowanzo buda muura hwako hudiki nerectum . Zvisinei, anogonawo kubuda mudumbu rako, appendix, uye gumbo. Dzimwe nguva, matumbu aya anogona kupararira kunze kwenzira yekugaya chikafu, senge kuchiropa chako .

Ndiani anonyanya kukanganiswa nedambudziko iri reGI NET?

Ichi chirwere chisingawanzoitiki. Zvichienderana nehuwandu, chirwere ichi chinobata vanhu vanosvika vana pavanhu 100,000 . Kunyangwe munyika yakaita seUnited States, vanhu vakuru vanosvika 8,000 chete ndivo vanoonekwa vaine chirwere ichi gore rega rega.

Dambudziko iri rinowanzo bata vanhu vane makore ari pakati pe55 ne65. Zvisinei, rinogona kuitika muvanhu vakuru vezera ripi zvaro. Varungu vane mukana wekuwana chirwere ichi kupfuura vatema. Zvakare, data rinoratidza kuti vakadzi vane mukana wekuwana `GI NET` iyi kupfuura varume.

Ndezvipi zviratidzo zveGI NET?

Heino chinhu chakakosha. Vamwe vanhu vanogona kuva nemabundu aya mumiviri yavo vasina zviratidzo . Dzimwe nguva anowanikwa netsaona kana chimwe chinhu chakaita se "scan" chaitwa nekuda kwechimwe chikonzero.

Zvisinei, kana zviratidzo zvikaonekwa, zvinogona kufanana nezvezvirwere zvakajairika, zvisina kunyanya kuoma. Ndosaka dzimwe nguva zvichigona kuonekwa kunonoka. Ona kana zviratidzo izvi zvichinzwika sekunge zvakajairika kwauri:

• Kurwadziwa kwemudumbu: Izvi zvinogona kuva chiratidzo chekuti wavhara ura, pamwe nekuda kwegomarara reGI NET.
• Manyoka:Kufamba-famba kwedumbu kakawanda. Chiratidzo ichi chinowanzoonekwa kuvanhu vane chirwere chinonzi ``Carcinoid Syndrome'' (chimwe chiratidzo chine chekuita ne ``NET''), kana kune avo vakavhiyiwa kubviswa nduru yavo kana chikamu chedumbu ravo.
• Kusvotwa nekurutsa: Kana kuda kurutsa nekurutsa zvikaramba zviripo, zvinogona kuva chiratidzo chechirwere chakakomba.
• Kudzikira uremu usingadi: Kana ukadzikira uremu nekukurumidza usingade kudya, kurovedza muviri, kana pasina chikonzero chakajeka, chiratidzo chinowanzoitika cheGI NETs.
• Ropa riri mutsvina: Kana tsvina yako yakatsvuka kana kuti yanonoka, izvi zvinogona kuva zviratidzo zvekubuda ropa mudumbu.
• Jaundice: Izvi zvinoita kuti ganda rako nemaziso machena zvishanduke kuita yero.
• Kuneta: Uku hakusi kungovata chete. Kunzwa kuneta zvikuru nguva dzese, usingakwanise kuita chero chinhu.

Yeuka kuti kungova nezviratidzo izvi hazvirevi kuti une GI NET. Zvisinei, kana zviratidzo izvi zvikaramba zviripo, zvakakosha kuti uone chiremba kuti akupe mazano.

Ndezvipi zvikonzero zveGI NET?

Kutaura zvazviri, vaongorori vezvekurapa havasati vawana chikonzero chaicho cheGI NETs. Zvisinei, vakaona kuti vanhu vane acid shoma mudumbu (hypochlorhydria) vane hukama nechirwere ichi.

Pamusoro pezvo, vanhu vane mamwe matambudziko ekuzvarwa nawo uye zvirwere zvemuviri vanogona kunge vari panjodzi yakakura yekuwana maGI NET. Mamwe ematambudziko aya anosanganisira:

• Multiple endocrine neoplasia (MEN): Kune mhando mbiri dzeizvi. Rudzi rumwe (MEN1) runokonzera kuti glands rako rethyroid, parathyroid, kana adrenal rishande zvakanyanya kana kuti riite bundu. Rumwe rudzi (MEN2) runokonzera kuti pancreas, pituitary, kana parathyroid glands rishande zvakanyanya kana kuti riite bundu.
• Chirwere cheVon Hippel-Lindau: Ichi chirwere chisingawanzoitiki. Chinokonzera bundu risiri rekenza (risina kuipa) kuti riumbe munzvimbo dzakasiyana dzemuviri.
• Neurofibromatosis rudzi rwekutanga: Ichi chirwere chisingawanzoitiki. Chinokonzera bundu paganda netsinga, uye chinogonawo kukanganisa maziso nedzimwe nhengo dzemuviri.

Vanachiremba vanoongorora sei chirwere ichi cheGI NET?

Kana uine zviratidzo zvataurwa pamusoro apa, kana paine fungidziro yechimwe chikonzero, vanachiremba vachaita bvunzo dzakasiyana-siyana.

• X-ray: Izvi zvinogona kutora mifananidzo yezviri mukati memuviri. Zvisinei, dzimwe nguva bundu reGI NET rakakura zvakanyanya kana kuti diki zvekuti harionekwe paX-ray. Kana zvakadaro, chiremba wako anogona kukurudzira mamwe marudzi ekuskena.
• Kuongororwa kweCT (computed tomography):Izvi zvinoshandisa komputa uye X-rays dzakatevedzana kuti pave nemaonero ezvikamu zvitatu (3D) zvenhengo dzako nemapfupa. CT scan inogona kuratidza zvinhu zvakaita sehukuru hwebundu uye kana rakapararira kuchiropa kana kune dzimwe nzvimbo.
• Kufungidzira kwemagnetic resonance (MRI): Kuedza uku kunoshandisa magineti, mafungu eredhiyo, uye komputa kuti ibudise mifananidzo yakajeka yenhengo dzako nemapfupa.
• Endoscopy: Mukuita uku, vanachiremba vanoshandisa endoscope, chinhu chakatetepa, chakaita sechubhu chine chiedza nekamera pamberi, kuti vatarise mukati menzira yako yepamusoro yekugaya. Chubhu iyi inogona kuiswa nemuromo wako kana mudumbu. Colonoscope inoshandiswa kutarisa chikamu chezasi chenzira yako yekugaya.
• Endoscopic ultrasound (EUS): Izvi zvinoshandisa endoscope nemafungu eruzha ane simba guru kutora mifananidzo yegadziriro yekugaya. Endoscope inopinzwa nemuromo kana mudumbu, uye probe iri kumagumo inotumira mafungu eruzha mudumbu. Manzwi anobuda munyama dziri mukati anogadzira mifananidzo inonzi sonograms.
• Positron emission tomography (PET) scan: Iyi bvunzo inoona bundu re neuroendocrine uchishandisa dhayi yakakosha (iyo yakagadzirirwa kuona masero e neuroendocrine bundu).
• Kuongororwa kwemuviri: Iyi ndiyo nzira inonyanya kushandiswa kusimbisa chirwere. Mukuita izvi, kanyama kadiki kanotorwa kubva panzvimbo inofungirwa uye kanoongororwa nemaikorosikopu kuti zvionekwe kana paine masero ekenza.

Kune mhando dzakasiyana dzemabundu e neuroendocrine here?

Ehe, vanachiremba vanoshandisa nzira yekuongorora kuti mabundu aya aonekwe sei. Izvi zvinovabatsira kuronga kurapwa kwavo. Danho rebundu rinoonekwa nekutarisa masero egomarara pasi pemaikorosikopu. Vanotarisa kuti masero mangani ari kupatsanuka, kuti ari kupatsanuka nekukurumidza sei, uye kuti masero akafanana sei nemasero egomarara pane masero ane hutano. Heano matanho e'GI NET':

• Giredhi 1 (bundu remhando yepasi): Masero aya anopatsanuka zvishoma nezvishoma. Izvi zvinoreva kuti bundu rinokura zvishoma nezvishoma.
• Giredhi 2 (bundu repakati nepakati): Mwero wekupatsanurana kwemasero aya uri pakati nepakati.
• Giredhi 3 (bundu repamusoro-soro): Masero aya anopatsanuka nekukurumidza, saka bundu rinokura nekukurumidza.

Ndeapi marapirwo eGastrointestinal Endocrine Tumors (GI NETs)?

Kune nzira dzakawanda dzekurapa GI NETs. Vanachiremba vanosarudza kurapwa kwakanakira iwe zvichienderana nezvinhu zvakawanda, kusanganisira giredhi regomarara rako, migumisiro inogona kuitika kubva mukurapwa, hutano hwako hwese, uye zvaunofarira iwe pachako. Kune nzira dzakawanda dzekurapa: kutarisa, kuvhiyiwa, uye kurapwa.

Chii chinonzi Active Monitoring?

Kana bundu iri richikura zvishoma nezvishoma uye riine njodzi shoma yekupararira kune dzimwe nhengo dzemuviri, vanachiremba vanogona kukurudzira kurapwa kunonzi "active surveillance." Izvi zvinosanganisira kukutarisa nguva nenguva , pane kutanga kurapwa kukuru ipapo ipapo.

• Miedzo yekufungidzira yakaita seCT scan.
• Kuongororwa kweropa kwakadai sekuongororwa kweropa rose (CBC).
• Kuongororwa kwemuviri.

Ndeapi maoparesheni anoitirwa GI NET?

Rudzi rwekuvhiyiwa kunoitwa paGI NET runoenderana nezvinhu zvakaita senzvimbo yebundu uye kana rakapararira kune dzimwe nhengo dzemuviri.

Zvakakosha kuti usati wavhiyiwa, timu yako yekuvhiya izive kana uine `(Carcinoid Syndrome)` (chirwere chinoratidza zviratidzo zve`neuroendocrine bundu`). Nekuti, kana uine `(Carcinoid Syndrome)`, kuvhiyiwa kunogona kukonzera matambudziko anogona kutyisidzira hupenyu. Kana chiremba wezvekuvhiya akaziva nezveizvi, achaedza kudzivirira matambudziko aya nekukupa mishonga yakakosha usati wavhiyiwa, panguva yekuvhiyiwa, uye mushure mekuvhiyiwa.

Mamwe mavhiyiwa anowanzoitwa eGI NET ndeaya:

• Kubviswa kwechikamu chedumbu: Izvi zvinosanganisira kubviswa kwechikamu chedumbu rako.
• Kubviswa kweura hudiki: Izvi zvinosanganisira kubvisa chikamu cheura hudiki chine bundu. Chiremba anogonawo kuita anastomosis (kubatanidzazve magumo maviri eura hwakachekwa). Ma lymph nodes ari pedyo neura hudiki anowanzo bviswa uye kuongororwa nemaikorosikopu kuti vaone kana paine masero ekenza.
• Kuvhiyiwa kweAppendectomy: Vanachiremba vanogona kubvisa appendix yako kuburikidza nekuchekwa kukuru kana kuburikidza nekuvhiyiwa kwe laparoscopic (kucheka kudiki nekamera yakaiswa).
• Kubviswa kweropa: Mukuita izvi, divi rekurudyi kana rekuruboshwe remuura mukuru rinobviswa, pamwe chete netsinga dzeropa dziri pedyo uye ma lymph nodes.
• Kubviswa kwepazasi kwepamberi: Vanachiremba vanobvisa chikamu cherectum yako, asi vanosiya anus yako isina kukuvadzwa. Izvi zvinokutendera kuti ushande zvakanaka.
• Kubviswa kwedumbu (APR): Kuvhiyiwa uku kunobvisa anus yako, rectum, uye chikamu cheura rako . Kuvhiyiwa uku kunowanzo perekedzwa ne colostomy. Izvi zvinoreva kuti panoitwa buri kubva muura rako kuenda pamusoro pedumbu rako kuitira kuti tsvina (tsvina yekugaya) ipfuure nepairi.
• Kubviswa kwechiropa: Kuvhiyiwa uku kunobvisa ma GI NETs akapararira kuchiropa.

Ndezvipi zvinetso kana migumisiro yekuvhiyiwa uku?

Kuvhiyiwa kwese uku kunogona kuva nemigumisiro yakaipa . Dzimwe nguva ungangoda rubatsiro rwakawedzerwa kumba paunenge uchipora. Bvunza chiremba wako zvaunotarisira mushure mekuvhiyiwa kwacho kwawakaita.

Ko kuvhiyiwa kweGI NET kuchakanganisa mararamiro angu here?

Ehe, zvinogona kuva nemigumisiro yakaipa . Sezvo kuvhiyiwa uku kuchiwanzobvisa chikamu chemuviri wako wekugaya, panogona kunge paine shanduko munzira yaunodya nekunwa, kunyangwe maendiro aunoita kuchimbuzi. Chiremba wako achatsanangura chaizvo kuti kuvhiyiwa uku kuchakukanganisa sei, uye zvaachaita kugadzirisa matambudziko ese ekugaya.

Ndedzipi dzimwe nzira dzekurapa dziripo dzeGI NET?

Dzimwe nguva vanachiremba vanogona kusanganisa nzira idzi dzekurapwa nekuvhiyiwa:

• Kurapa nemakemikari: Izvi zvinoshandisa mhando dzakasiyana dzemishonga yakagadzirirwa kuuraya masero ekenza.
• Kurapa kwakanangana: Izvi zvinoshandisa mishonga kana zvimwe zvinhu zvinorwisa masero ekenza chete, pasina kukuvadza masero ane hutano hwakanaka.
• Kurapa nekudzivirira muviri: Izvi zvinoshandisa masoja emuviri wako kuuraya masero egomarara kana kuamisa kukura.
• Kurapa nemwaranzi: Izvi zvinoshandisa simba rakasimba kuuraya masero ekenza kana kuamisa kukura.
• Masomatostatin analogues: Aya ndiwo marudzi esynthetic hormone somatostatin. Somatostatin yako inoshanda nekumisa muviri wako kugadzira mahormone akawandisa.

Ndezvipi migumisiro kana matambudziko ekurapa uku?

Kurapa kwega kwega uku kunokanganisa munhu mumwe nemumwe zvakasiyana. Saka, zvakakosha kukurukura zvakajeka mabhenefiti nemigumisiro yekurapwa kwega kwega nachiremba wako. Izvi zvichakubatsira kunzwisisa kuti kurapwa kwega kwega kuchakanganisa sei iwe. Chiremba wako achakurudzira kurapwa zvichienderana nehutano hwako uye zvaunofarira iwe pachako.

Matumbu eEndocrine emudumbu anogona kudzivirirwa here?

Zvinosuwisa kuti pari zvino hapana nzira yekudzivirira GI NETs. Zvisinei, vaongorori vezvekurapa vakawana hukama pakati pemamwe ma syndromes enhaka uye/kana mamiriro ehutano nenjodzi yekuve nemabundu e neuroendocrine. Taura nachiremba wako nezvenhoroondo yako yezvekurapa uye nhoroondo yezvekurapa yemhuri yako. Anogona kukurudzira bvunzo dzakakosha kuti uone zviratidzo zveGI NETs pakutanga, ​​kuti bundu rigone kubatwa uye kurapwa nekukurumidza.

Kana ndine chirwere ichi, chii chandinofanira kutarisira?

Kufanotaura kwako nezvegomarara kunoenderana nekuti kenza ichaonekwa riini uye kuti yatanga kurapwa riini. Vanhu vanosvika 97% vanorapwa kenza isati yapararira kune dzimwe nhengo dzemuviri vachararama.Makore mashanu mushure mekuonekwa kwechirwere ichi. Kana bundu racho rapararira kune nhengo dzemuviri dziri pedyo kana kuti lymph nodes, mwero wekurarama kwemakore mashanu unoderera kusvika pa95%. Vanhu vanosvika 67% vane GI NETs dzakapararira kunze kwenzira yekugaya vanorarama makore mashanu mushure mekuonekwa kwechirwere ichi.

GI NET inogona kudzoka. Zvichienderana nehukuru, giredhi, uye nzvimbo yebundu, ungangoda kuongororwa nguva nenguva. Semuenzaniso, chiremba wako anogona kukurudzira kuti uitwe CT scan kamwe chete pagore kwemakore matatu ekutanga mushure mekurapwa uye kuongororwa kwemuviri gore rega rega. Bvunza chiremba wako nezvekuongororwa kwekutevera uye bvunzo dzinoenderana nemamiriro ako ezvinhu.

Ndinozvitarisira sei?

Kana uine bundu remudumbu, ungangoda kuvhiyiwa. Vanachiremba vanowanzo gadzira maburi akavhurika, ayo akakura kupfuura laparoscopic surgery. Izvi zvinoreva kuti uchafanira kugara muchipatara kwemazuva mashoma wozopora uri kumba kwemavhiki mashoma.

Ndinofanira kuenda kuEmergency Room riini?

Unogona kugara uchitevera chiremba wako kuti uone kana kenza yako yadzoka. Bvunza chiremba wako kuti zviratidzo zvipi zvinogona kunge zviri zviratidzo zvechirwere chakakomba mushure mekuvhiyiwa. Kana ukaona chimwe chezviratidzo zvinotevera, unofanira kutsvaga rubatsiro rwechiremba nekukasika:

• Kutadza kufema zvakanaka kamwe kamwe.
• Kana fivha iri pamusoro pe100.4 degrees Fahrenheit (38.3 degrees Celsius).
• Kana kurwadziwa kwacho kwakanyanya, kana kuti kusingagone kudzorwa nemushonga wako wekurwadziwa kwemusoro.
• Kana paine hurwa hwakasvibira, hunonhuwa, hunobuda paronda rekuvhiyiwa, kunyanya kana nzvimbo yakatenderedza ronda ichipisa kana ukanyatsoibata, kana kuti yakatsvuka zvikuru.
• Kana uchiramba uchirutsa kana kuti uchirwara nemanyoka.

Bundu remudumbu rinonzi gastrointestinal neuroendocrine bundu (GI NET) rinogona kuchinja hupenyu. Izvi zvinodaro nekuti vanhu vazhinji vane chirwere ichi vanofanirwa kuvhiyiwa kuti vabvise chikamu chedumbu ravo kana zvese zviri mudumbu ravo. Kuvhiyiwa kwako kunogona kuchinja nzira yaunodya, yekunwa, uye yekuenda kuchimbuzi. Chikwata chako chekurapa chinoziva kuti kugadzirisa shanduko idzi hakusi nyore nguva dzose. Kana uine mibvunzo kana zvinokunetsa, zviudze chiremba wako. Vachanzwisisa mamiriro ako ezvinhu uye vachakubatsira kuwana mhinduro.

Ndezvipi zvinhu zvakakosha zvatinofanira kuyeuka kubva munyaya iyi?

• `GI NET` rudzi rwegomarara risingawanzoitiki, asi zvakakosha kuti uzive nezvaro.
• Vamwe vanhu vanogona kunge vaine izvi vasina zviratidzo , asi ziva zviratidzo zvakaita sekurwadziwa mudumbu, manyoka, uye kudzikira uremu netsaona.
• Regai izvi zvikure.Chikonzero chaicho hachisati chawanikwa, asi zvimwe zvinhu zvinogarwa nhaka zvinogona kukonzera izvi.
• Kune nzira dzakasiyana-siyana dzekuongorora zvirwere, dzakadai se `CT scan`, `MRI`, `Endoscopy`, uye `Biopsy`.
• Nzira dzekurapa dzinosanganisira kuvhiyiwa, chemotherapy, uye radiation therapy . Chiremba wako ndiye achasarudza kuti ndeipi nzira yekurapa yakakunakira.
• Kuongororwa kwechirwere nekukurumidza uye kutanga kurapwa kunowedzera mikana yekupora.
• Kana muine kusava nechokwadi kana mibvunzo nezvenyaya iyi, musatya kutaura nachiremba wenyu . Varipo kuti vakubatsirei.

` GI NET, Matumbu eNeuroendocrine emudumbu, Kenza, Kenza yeMudumbu, Matumbu eNeuroendocrine, Sisitimu yekugaya, Zviratidzo