Wakambozvibvunza here kuti simba iri rinobva kupi patinodya chimwe chinhu chakaita semupunga kana chingwa? Zvakare, wakambozvibvunza here kuti tinowana sei simba ratinoda kuti tiite maekisesaizi, kumhanya, kana kusvetuka? Simba ratinowana kubva muchikafu chatinodya rinochengetwa kune imwe nzvimbo mumuviri wedu kuti rizoshandiswa gare gare. Zvakafanana nekuchengetedza bhatiri refoni yedu richichaja kana kuva netangi remafuta mumotokari yedu. Nzira huru iyo muviri wedu unochengeta simba inonzi glycogen, yatiri kutaura nezvayo nhasi.
Chii chinonzi glycogen, zviri nyore?
Zvichitaurwa zviri nyore, glycogen rudzi rweglucose inochengetwa mumiviri yedu. Funga nezvazvo nenzira iyi. Makabhohaidhiretsi atinodya, akadai semupunga, chingwa, mbatatisi, mbatatisi, nemichero, anogayiwa uye anoshandurwa kuita shuga iri nyore inonzi glucose mukati memiviri yedu. Glucose iyi ndiyo sosi huru yesimba kumasero emuviri wedu, kunyanya uropi. Kungofanana nemota inoda peturu kuti ishande, miviri yedu inoda glucose kuti ishande.
Zvino, mushure mekudya, shuga yakawanda kupfuura inodiwa nemuviri wedu kuti uwane simba inobva yawedzerwa muropa. Saka pane kungorasa shuga iyi yakawedzerwa, muviri wedu unoiunganidza nekuchenjera, wobatanidza zviuru zvemamorekuru madiki eglucose pamwe chete kuti ugadzire molekyuru hombe. Ndizvo zvatinodaidza kuti glycogen.
Glucose yakafanana nekubata mari mumaoko edu. Asi sekungoisa mari yakawandisa mubhangi, muviri unochengeta glucose yakawandisa seglycogen.
Maitiro aya anoitika nerubatsiro rwemapuroteni akakosha anonzi maenzyme.
- Maitiro ekugadzira glycogen kubva kuglucose anonzi Glycogenesis .
- Maitiro ekuputsa glycogen yakachengetwa kuti igadzire glucose kana ichidikanwa anonzi glycogenolysis .
Kunyange zvazvo mazita maviri aya angaita seanonyanya kutaurwa nezvesainzi, ingoyeukai, rimwe nderekuchengetera, uye rimwe nderekutorwa kubva mudura.
Glucose, glycogen, uye glucagon: Musiyano uripo pakati pezvinhu zvitatu izvi ndeupi?
Vanhu vazhinji vanovhiringidzika nekuti mazita matatu aya anonzwika zvakafanana. Zvisinei, matatu aya anoita mabasa matatu akasiyana zvachose. Ngatitarisei tafura iri pazasi kuti tinzwisise izvi zvakajeka.
| Zita | Zvichitaurwa zviri nyore... | Basa guru |
|---|---|---|
| Glucose | Uyu ndiwo 'peturu' yemuviri wedu. Kureva kuti, ndiwo musimboti wayo mukuru wesimba. Shuga iri nyore inogadzirwa nemakabhohaidhiretsi atinodya. | Kupa simba nekukurumidza kumasero, kunyanya kukosha pakushanda kwehuropi. |
| Glycogen | Iyi ndiyo 'simba remagetsi' mumuviri wedu. Ndiko kuchengetwa kweglucose. | Kuchengeta glucose kuti tishandise kana tichida simba (semuenzaniso, patinenge tichitsanya, tichiita maekisesaizi). |
| Glucagon | Iyi ndiyo 'kiyi' yekuchengetera zvinhu. Kureva, hormone. | Kana huwandu hweshuga muropa (glucose) hukadzikira, hunogadzirwa nepancreas uye hunopa chiropa chiratidzo chekuti glycogen iparadzwe yoichinja kuita glucose zvakare. |
Unonzwisisa musiyano here? Glucose isimba. Glycogen isimba rakachengetwa. Glucagon ihomoni inoudza muviri kuti ubudise simba kubva mudura. Homoni inoshanda kurwisa izvi, kureva kuti, kana shuga yeropa ikawedzera, inobatsira kuichengeta seglycogen, iinsulin .
Glycogen inochengetwa kupi mumuviri?
Muviri wedu unochengeta chitoro ichi chesimba chinokosha munzvimbo mbiri.
1. Chiropa: Chiropa chedu inzvimbo huru yekuchengetera zvinhu. Chikamu chikuru chehuremu hwechiropa chinogona kuumbwa neglycogen.
2. Tsandanyama dzeMapfupa: Tsandanyama dziri mumuviri wedu dzinochengeta glycogen yakawanda. Nekuti tsandanyama dzakakura kupfuura chiropa, chikamu chimwe muzvina chete cheglycogen yemuviri ndiyo inochengetwa mutsandanyama.
Kuwedzera kune idzi nzvimbo mbiri huru, huwandu hushoma hweglycogen hunochengetwawo munhengo dzakadai sehuropi.
Huwandu hweglycogen mumiviri yedu hahugari hwakafanana mukati mezuva rose. Hunochinja. Pane zvinhu zvakawanda zvinokanganisa:
- Huwandu hwemakabhohaidhiretsi aunodya:Kana ukadya chikafu chine makabhohaidhiretsi akawanda, glycogen yako inozara.
- Kusadya Nguva Dzekudya: Kana ukapedza maawa akawanda usina kudya, muviri wako uchashandisa zvinhu izvi kuti uwane simba, zvichikonzera kudzikira kwehuwandu hweglycogen mumuviri. Kazhinji, kutsanya kwemaawa 12-24 kunoita kuti glycogen iderere muchiropa.
- Huremu hwemaekisesaizi uye simba: Kana uchiita maekisesaizi akaomarara, kunyanya maekisesaizi emhando yepamusoro, glycogen iri mutsandanyama dzako inodzikira nekukurumidza.
Chii chinoitika kuglycogen mumuviri?
Glycogen inochengetwa muchiropa netsandanyama inoita mabasa maviri akasiyana. Ose anoshanda nenzira yeudyire.
Basa rekuchengetedza glycogen muchiropa
Glycogen iri muchiropa yakafanana negrid yemagetsi yenyika iyo inogovera simba kunyika yese. Inowanikwa mumuviri wese.
Basa guru reglycogen muchiropa nderekuchengetedza huwandu hweshuga muropa hwakagadzikana.
Uropi hwedu hunoda glucose nguva dzose. Kana ikaderera zvishoma, tinotanga kunzwa dzungu uye kusuruvara. Saka, patinenge tiri pakati pekudya kana kurara husiku, kana pasina glucose itsva muropa, huwandu hweshuga muropa redu hunoderera.
Panguva ino, pancreas yedu inogadzira hormone inonzi glucagon . Hormone iyi inoenda kuchiropa yotumira chiratidzo chekuti, "Zvakanaka, zvino pwanya glycogen yakachengetedzwa wogadzira glucose woiburitsa muropa." Chiropa chobva chagadzira glucose choiburitsa muropa. Glucose iyoyo inofamba nemuropa ichienda kumuviri wese, kunyanya kuuropi, ichipa simba rinodiwa. Ndokusaka tichigona kuramba takamuka kwemaawa akawanda tisina kudya.
Basa rekuchengetedza glycogen mutsandanyama
Glycogen iri mutsandanyama yakafanana nejenareta inongowanikwa mumba chete. Inoshandiswa netsandanyama iyoyo chete.
Masheya eglycogen ari mutsandanyama ane udyire. Anoshandisa glycogen iyoyo chete kupa simba kutsandanyama iyoyo. Haaiparadzi kuti igadzire glucose yoiisa muropa.
Patinofamba, kumhanya, kana kusimudza zvinorema, tsandanyama dzedu dzinoda simba rakawanda kuti dziite chero kufamba. Kana tikaedza kuwana simba iri kubva kuglucose iri muropa, shuga iri muropa ichapera nekukurumidza.
Saka, zvakasikwa zvakagadzira zvinoshamisa dura resimba mukati memhasuru dzazvinogona kushandisa pachadzo, kureva zvitoro zveglycogen. Patinongotanga kurovedza muviri, tsandanyama dzinopwanya glycogen iyi kuti dzigadzire simba radzinoda.
Fungidzira mutambi wekiriketi achimhanya pakati pekumhanya. Kana kuti mutambi achimhanya mamita zana. Munguva yemitambo yakasimba kudaro, tsandanyama dzinoda simba rakawanda nekukasika. Ndipo panochengetwa glycogen iyi. Ndosaka vatambi vachiudzwa kuti vadye chikafu chine makabhohaidhiretsi (carbs-loading) vasati vakwikwidza, kuti vazadze glycogen yakawanda.
Chii chinonzi Glycogen Storage Disease (GSD)?
Ichi chirwere chisingawanzoitiki, chinogara nhaka. Takataura nezvekuti miviri yedu inoda sei marudzi akasiyana ema enzymes kuti igadzire glycogen uye iigayiwe kuti igadzire glucose. Mumunhu ane GSD, rimwe kana akawanda ema enzymes aya anenge asipo kana kuti asiri kushanda zvakanaka.
Nekuda kweizvozvo, muviri wemunhu haugone kugadzira, kuchengeta, kana kuputsa glycogen nemazvo kana zvichidikanwa. Izvi zvinogona kukonzera kukuvara kwechiropa, kushaya simba kwetsandanyama, uye kuderera kwemazinga eshuga muropa (hypoglycemia). Kune mhando dzakasiyana dzeGSD, zvichienderana nekushaikwa kwema enzyme. Kazhinji, zviratidzo izvi zvinotanga kuonekwa muhucheche.
Chinhu chinonyanya kukosha ndechekuti chirwere ichi hachiwanzoitiki, saka hapana chikonzero chekutya.
Pane here bvunzo dzakakosha dzekutarisa mazinga eglycogen mumuviri?
Hapana bvunzo imwe chete inogona kuyera zvakananga kuti, "Ndine glycogen yakawanda sei mumuviri wangu?" Nekuti, sezvatakambotaura, huwandu ihwohwo hunoramba huchichinja mukati mezuva, zvichienderana nezvatinodya nezvatinoita.
Zvisinei, kana zviratidzo zvako zvichiratidza dambudziko nekushanda kwemuviri wako kweglycogen, chiremba wako anogona kukurudzira mimwe miedzo yekutarisa mamiriro akaita seGSD.
| Bvunzo | Uri kuonei? |
|---|---|
| Kuongororwa kweRopa | Mapaneru ekushanda kwechiropa neitsvo anoongororwa. Mazinga eshuga muropa anoongororwawo. Vanhu vane GSD vanowanzova nemazinga eshuga muropa akaderera. |
| Ultrasound yedumbu | Izvi zvinobatsira kutarisa kana chiropa chakura. Kana glycogen isingashandiswe nemazvo, inogona kuungana muchiropa yozvimba. |
| Kuongororwa kweTishu | Kanyama kadiki kanotorwa kubva muchiropa kana tsandanyama uye huwandu hweglycogen kana ma enzyme hunoyerwa. |
| Kuedzwa kwemajini | Kuongororwa uku kunogona kuitwa kuti kusimbiswe kana paine shanduko dzemajini dzine chekuita neGSD. |
Kana muine kusava nechokwadi nezvezviratidzo izvi, chinhu chakanakisa chekuita ndechekuona chiremba wemhuri yenyu motaura nezvazvo.
Mharidzo Yekuenda Nayo Kumba
- Glycogen ndiyo nzira huru yekuchengetedza simba mumuviri wedu. Yakafanana ne'simba remagetsi' remuviri wedu.
- Izvi zvinonyanya kuchengetwa muchiropa netsandanyama.
- Glycogen iri muchiropa inobatsira kudzora huwandu hweshuga muropa uye kupa simba kumuviri wese.
- Glycogen iri mutsandanyama inoshandiswa kupa simba kutsandanyama idzodzo, kunyanya panguva yekurovedza muviri.
- Kuti urambe uine glycogen yakawanda mumuviri, kunyanya kana uri mutambi, zvakakosha kudya chikafu chine makabhohaidhiretsi akakwana zuva nezuva.
- Matambudziko ane chekuita neGlycogen haawanzoitiki, uye zvakakosha kutaura nachiremba wako kana uine zvinokunetsa.
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