Ko calcium yakawanda muropa rako here? Ngatitaurei nezveHypercalcemia nenzira iri nyore!

Dzimwe nguva unonzwa kuneta, kurwadziwa kwemuviri, kana kugara uine nyota here? Ungafunga kuti izvi zvinhu zvakajairika. Asi izvi zvinogonawo kuva zviratidzo zvehuwandu hwecalcium muropa rako. Ndizvo zvatinodaidza kuti hypercalcemia mukurapa. Usazvidya mwoyo, kazhinji izvi hazvisi dambudziko rakakura. Ngatitaurei nezvezvinhu zvese nenzira iri nyore uye yakajeka.

Zvichitaurwa zviri nyore, chii chinonzi Hypercalcemia?

Hypercalcemia inguva yekuti une calcium yakawanda muropa rako kupfuura yakajairika. Dzimwe nguva inogona kungova yakakwira zvishoma, dzimwe nguva inogona kuva yakakwira zvakanyanya. Zvakare, kune vamwe vanhu inguva pfupi uye inonyangarika, nepo kune vamwe inogona kuva yehupenyu hwese.

Zvino ungave uchifunga kuti, calcium yakanaka kumapfupa, saka chii chinoitika kana calcium iri muropa ikawedzera? Ichokwadi kuti calcium yakawanda mumuviri wedu iri mumapfupa edu. Asi, panofanira kunge paine calcium muropa futi. Unoziva here kuti nei?

• Kuti tsinga dzedu dzishande zvakanaka: Calcium inokosha pakutumira mameseji kuburikidza netsinga.
• Kushanda kwetsandanyama: Calcium inobatsira tsandanyama dzedu kusimba uye kuzorora, zvinoreva kuti tinofamba.
• Kugwamba kweropa: Kana paine kukuvara pane imwe nzvimbo uye ropa richiyerera, calcium inodiwa kuti ropa rigwambare kuti ropa rimire kubuda.
• Mashandiro emoyo: Calcium inoita basa rakakosha zvikuru mukuchengetedza moyo wedu uchirova zvakanaka.

Nekuti inoita zvinhu zvakawanda zvakakosha, muviri wedu unonyatso dzora huwandu hwecalcium muropa redu. Mahormone maviri anobatsira neizvi. Ndiwo parathyroid hormone necalcitonin . Pamusoro pezvo, vhitamini D inokoshawo kuti muviri utore calcium kubva muzvikafu zvatinodya.

Ndeupi musiyano uripo pakati peHypercalcemia neHypocalcemia?

Mazwi maviri aya anonzwika akafanana zvishoma, handiti? Asi ane zvazvinoreva zvakasiyana zvachose. Mukurapa, izwi rekuti "Hyper" rinoreva "zvakawandisa." "Hypo" rinoreva "zvishoma." Saka musiyano uripo pakati pemaviri aya uri nyore.

Ndiani angangonyanya kuva nechirwere ichi?

Hypercalcemia inogona kuitika chero pazera ripi zvaro, kune chero munhu. Zvisinei, inowanzoonekwa muvakadzi vanopfuura makore makumi mashanu , kunyanya mushure mekuguma kuenda kumwedzi. Kazhinji, inokonzerwa neparathyroid gland inoshanda zvakanyanya, yatakakurukura kare.

Zvinofungidzirwa kuti pakati pe1% ne2% yevanhu vose vane chirwere ichi. Pavanhu ava, 90% vanonzi vane hypercalcemia inokonzerwa nedambudziko reparathyroid glands (primary hyperparathyroidism) kana chirwere chegomarara.

Hypercalcemia inotyisidzira hupenyu here?

Zvisinei, kana calcium yakawanda zvakanyanya (hypercalcemia yakanyanya), zvinogona kukonzera matambudziko akakomba. Muchiitiko chakadaro, rubatsiro rwechiremba runodiwa nekukurumidza. Muchiitiko chakadaro chakakomba, zvinotevera zvinogona kuitika:

• Kukundikana kweitsvo
• Kurova kwemoyo kusina kurongeka (Arrhythmia)
• Kuvhiringidzika
• Kushaya simba

Saka, kunyange zvazvo izvi zvisingawanzove zvakakomba, hazvisi zvinhu zvekurerutsa.

Ndezvipi zviratidzo zveHypercalcemia?

Sezvatakambotaura, vanhu vazhinji vanogona kusaona zviratidzo, kunyanya kana huwandu hwecalcium yavo hwakangokwira zvishoma. Zvisinei, kana huwandu hwecalcium hwakakwira zvakanyanya kana chirwere chikaramba chiripo kwenguva yakareba, zviratidzo zvinotevera zvinogona kuitika.

Sei calcium muropa ichiwanda seizvi? Ndezvipi zvinokonzera?

Kune zvikonzero zvakawanda zvinokonzera hypercalcemia. Zvimwe zvirwere, mishonga, uye kushaya mvura mumuviri zvinogona kukonzera izvi. Asi zvikonzero zvikuru zviviri ndezvekuti parathyroid glands inoshanda zvakanyanya uye kenza.

1. Dambudziko reParathyroid gland (Primary Hyperparathyroidism)

Fungidzira kuti kune vanamukoti vana vadiki mumuviri wedu vanodzora huwandu hwecalcium. Aya magland mana eparathyroid ari mumutsipa wedu, kuseri kwegland rethyroid. Basa rawo guru nderekugadzira parathyroid hormone (PTH), iyo inodzora huwandu hwecalcium muropa. Kana rimwe kana akawanda emagland aya akatanga kushanda zvakanyanya nekuda kwechimwe chikonzero, calcium yakawandisa inoungana muropa. Ichi ndicho chikonzero chikuru che hypercalcemia.

2. Gomarara

Mamwe marudzi egomarara anogonawo kukonzera calcium yakawanda muropa. Izvi zvinonzi hypercalcemia yekenza. Hypercalcemia inokonzerwa negomarara inowanzo kurumidza uye inogona kuva yakakomba. Mamwe marudzi egomarara anogona kukonzera izvi ndeaya:

• Kenza yemapapu
• Kenza yemazamu
• Multiple myeloma, kenza yemasero machena eropa
• Kansa yemasero eitsvo
• Leukemia neLymphoma
• Rhabdomyosarcoma

3. Mimwe mishonga

Dambudziko iri rinogonawo kukonzerwa nemimwe mishonga nemavhitamini atinotora.

• Thiazide diuretics: Mimwe mishonga yekukweva ropa (semuenzaniso, Hydrochlorothiazide) inoshandiswa kurapa BP yakakwira uye kuchengetedza mvura mumuviri.
• Lithium: Mushonga unoshandiswa kurapa zvimwe zvirwere zvepfungwa.
• Mavhitamini necalcium: Kutora vhitamini D yakawandisa, vhitamini A, kana zvimwe zvinowedzera calcium.
• Mishonga Inorwisa Asidhi: Kutora mapiritsi ecalcium carbonate akawandisa (akadai seTums® kana Rolaids®) atinowanzo nwa pakurapa chirungurira kunogona kuwedzera calcium kwenguva pfupi.

4. Zvimwe zvikonzero

Pamusoro peizvi, kune zvimwe zvikonzero zvisingawanzoitiki.

• Zvirwere zvemapapu zvakaita se sarcoidosis ne TB.
• Kukundikana kweitsvo.
• Hyperthyroidism (kuora kwehomoni yethyroid).
• Kugara pamubhedha kwenguva yakareba.
• Zvirwere zvine chekuita nemapfupa zvakaita sePaget's disease of the bone.

Ungaziva sei chirwere ichi?

Kazhinji kacho inowanikwa panguva yekuongororwa ropa nguva dzose kwaunoita nekuda kwechimwe chikonzero. Miedzo yakaita seComprehensive Metabolic Panel (CMP) kana Basic Metabolic Panel (BMP) inoyerawo huwandu hwecalcium muropa. Izvi zvinogona kubatsira kuiona zviratidzo zvisati zvaonekwa.

Chiremba wako achaona kuoma kwechirwere ichi zvichienderana nehuwandu hwecalcium muropa rako.

Kana calcium yakawanda muropa rako, chiremba wako achakuongorora, obvunza nezvemishonga yako uye nhoroondo yezveutano hwemhuri yako. Kana pasina chikonzero chakajeka chingawanikwa, unogona kutumirwa kuna chiremba we endocrinologist.

Zvinogoneka kuti mimwe miedzo yakawanda ingaitwa kuti pave nechikonzero chaicho.

• Kuongororwa kweropa kunoongorora huwandu hwehomoni yeparathyroid (PTH).
• Kuongororwa ropa kuti uone huwandu hwevhitamini D.
• Kuongororwa kunoongorora huwandu hwecalcium muweti.
• Kuongororwa kweultrasound kana CT scan kuti uone kana paine bundu kana kuzvimba mumagland eparathyroid.

Inorapwa sei?

Kurapwa kwe hypercalcemia kunoenderana nechikonzero uye kuoma kwechirwere chacho.

Kune mamiriro ekunze asina kusimba

Kana calcium yako yakakwira zvishoma, chiremba wako anogona kukukurudzira kuti:

• Inwa mvura yakawanda: Izvi zvinoderedza kupera mvura mumuviri uye zvinobatsira kubvisa calcium yakawandisa kuburikidza neweti.
• Kuchinja mishonga: Kana uri kutora mishonga yerudzi rwethiazide yeBP yakakwira, unogona kukumbirwa kuti uchinje kune imwe mishonga.
• Kurega kushandisa mishonga yekuwedzera: Rega kutora mishonga yekuwedzera yecalcium kana vhitamini D, mapiritsi ekuderedza acid ane calcium, kana kuderedza huwandu hwemishonga.

Kurapa zvichienderana nechikonzero

• Kana paine dambudziko nemagland eparathyroid: Kazhinji, kurapwa kwakanakisa ndekwekuvhiya kubvisa gland kana magland anoshanda zvakanyanya.
• Kana chirwere ichi chakakonzerwa negomarara: Mishonga yakaita sebisphosphonates kana denosumab inogona kupihwa.

Kune zvirwere zvakakomba

Zvisinei, kana calcium yakawanda mumuviri wako uye zviratidzo zvako zvakanyanya, chiremba wako anogona kusarudza kukugamuchira kuchipatara uye kukupa mvura yemutsinga (IV fluids) nedzimwe nzira dzekurapa. Izvi zvinogona kuderedza calcium yako nekukurumidza uye kudzivirira matambudziko.

Ndezvipi zvinetso zvinogona kuitika nekuda kwechirwere ichi?

Matambudziko anotora nguva refu haawanzoitiki nekuti chirwere ichi chinowanzoonekwa nekukurumidza. Zvisinei, kana chikasarapwa kwenguva yakareba, matambudziko anotevera anogona kuitika:

• Kuwanda kwecalcium muitsvo (Nephrocalcinosis) uye kusashanda zvakanaka kweitsvo.
• Matombo eitsvo.
• Kukwira kweropa (BP).
• Kuora mwoyo.
• Osteoporosis uye kutyoka kwemapfupa kuri nyore.

Zvinogona kudzivirirwa here? Ndinofanira kuona chiremba riini?

Hazvisi zvese zviitiko zve hypercalcemia zvinogona kudzivirirwa. Zvisinei, pasina zano rachiremba wako,Kuchenjera kusatora mapiritsi ecalcium, mavhitamini, uye mishonga inorwisa asidhi ine calcium zvisina kufanira.

Paunofanira kuenda kuna chiremba:

• Kana mumwe munhu mumhuri yako ane nhoroondo ye calcium yakawanda, chirwere cheparathyroid, kana matombo eitsvo, taura nachiremba wako nezvazvo.
• Kana uine chimwe chezviratidzo zvatakakurukura munyaya ino (zvakaita senyota yakawandisa, kuita weti nguva nenguva, kurwadziwa mumuviri, kuda kurutsa), enda kuna chiremba nekukasika.

Zvakajairika kuti unzwe kutya uye kuzvidya mwoyo kana uchangobva kuongororwa kuti une chirwere. Asi yeuka, hypercalcemia chirwere chinorapika. Kana huwandu hwecalcium mumuviri wako hwadzoka pahwakajairika, zviratidzo zvako zvinopera. Usatya kubvunza chiremba wako chero mibvunzo yauinayo nezveizvi.