Masero eropa rako haasi kuumbwa nemazvo here? Ngatidzidzei nezveMyelodysplastic Syndrome (MDS)!

Unonzwa kuneta uye kuneta nguva dzese here? Dzimwe nguva unomboomerwa nekufema kunyangwe mushure mekuita basa diki here? Kana kuti unoona mavanga uye kubuda ropa kwese kwese mumuviri wako here? Kunyangwe uchifunga kuti izvi zvinhu zvakajairika, dzimwe nguva panogona kunge paine chikonzero chiri shure kweizvi chaunofanira kunetseka nacho. Nhasi tichataura nezvechimwe chirwere chakadai, chinonzi myelodysplastic syndrome.

Chii chinonzi myelodysplastic syndrome (MDS)?

Iye zvino ngationei kuti iyi Myelodysplastic Syndrome (MDS) chii. Vamwe vanhu vanoidaidzawo kuti Myelodysplasia. Munguva pfupi yapfuura, inonziwo Myelodysplastic Neoplasm. Zvichitaurwa zviri nyore, imhando yekenza . Asi zvinoitika mune izvi ndezvekuti masero ekutanga anogadzira ropa mumuviri wedu - atinodaidza kuti (masero eropa) - haakure zvakanaka, kureva kuti, haakure zvakanaka. Masero aya ari mumongo wedu wemapfupa. Saka dambudziko rinotanga kana masero aya ekutanga asingakure zvakanaka uye ova masero matsvuku eropa ane hutano, masero machena eropa, uye maplatelet.

Kana muviri wako usina masero eropa akakwana ane hutano, unogona kuva nematambudziko akakomba akadai seanemia. Unogonawo kuwana hutachiona kakawanda uye kubuda ropa kakawanda. Mune vamwe vanhu, MDS inogona kuipa yozokura kuita kenza inonzi acute myeloid leukemia (AML) .

Chirwere ichi, chinonzi MDS, hachiwanzoitiki . MuUnited States, chinobata vanhu vanosvika vana pavanhu 100,000 vega vega gore rega rega. Kana ukaonekwa uine MDS, vanachiremba vako vachaedza kuderedza kufambira mberi kwechirwere, kudzora zviratidzo zvako, uye kurapa chero matambudziko angamuka.

Ndeapi marudzi eMDS aripo?

Vanachiremba vanopatsanura chirwere ichi cheMDS mumhando dzakasiyana-siyana. Vanotarisa mhedzisiro yebvunzo dzakasiyana-siyana. Ngatitarisei kuti bvunzo idzodzo dzinotsvagei:

• Masero eropa matsvuku nemachena ane hutano uye huwandu hwemaplatelet: Kana masero matsvuku eropa ako ari mashoma, tinoati anemia. Unganzwa kuneta zvakanyanya uye kushaya mweya.
• Masero eropa asati akura, kana kuti ma blasts: Ma blasts aya akafanana nemasero eropa asati akura. Anotora nzvimbo yakawanda mumongo wemapfupa, zvichiita kuti zviomere masero eropa ane hutano kuumbwa. Kana usina masero machena eropa ane hutano akakwana, unogona kuwana hutachiona kakawanda. Uye kana usina maplatelet akakwana ane hutano, zvinogona kuoma kumisa kubuda ropa.
• Sideroblasts:Aya masero matsvuku eropa asina kukura zvakanaka. Chinonyanya kukosha paari ndechekuti pachinzvimbo chekushandisa iron kugadzira hemoglobin, anochengeta iron. Unoziva, hemoglobin ipuroteni inobatsira masero edu matsvuku eropa kutakura okisijeni mumuviri wese. Iron inokosha pakuita izvi. Saka, kana vanachiremba vezvirwere vakaona aya ma sideroblasts, zvinoreva kuti hemoglobin yako haisi kushanda zvakanaka.
• Kusarongeka kwema chromosome: Ma chromosome ndiwo mativi emasero edu ane majini. Majini anoumbwa neDNA. Kana paine kusarongeka muma chromosome aya, zvinoreva kuti pane chakakanganisa DNA yako uye chakakonzera shanduko muma chromosome mumasero ako eropa.

Ndezvipi zviratidzo zve myelodysplastic syndrome?

Yeuka, dzimwe nguva unogona kuva neMDS usingaratidze zviratidzo. Muzviitiko zvakadaro, chirwere ichi chinowanikwa netsaona panguva yekuongororwa ropa nguva dzose. Chiratidzo chikuru chinowanikwa nevanhu vazhinji inhamba shoma yemasero matsvuku eropa, kana kuti anemia. Zvisinei, zviratidzo zveanemia nezvimwe zviratidzo zveMDS zvinogona kufanana nezvezvimwe zvirwere zvisina kunyanya kuipa.

Saka, kana ukaona chero shanduko dziri pazasi, kunyanya kana dzisingapere mushure memavhiki mashoma, iva nechokwadi chekuona chiremba.

• Kana uchinzwa seusingakwanise kufema (tinoti dyspnea).
• Kana uchinzwa usina simba kana kuti waneta zvakanyanya , uye kuneta kusingaderere kunyangwe mushure mekuzorora zvakakwana.
• Kana ukaona kuti ganda rako rachenuruka kupfuura zvawagara uchiita. Pamwe kana uine ganda rakasviba, chiremba achaongorora kana paine kurasikirwa kweruvara mukati memaziso ako ezasi, mukati memuromo wako, uye mukati memhino dzako.
• Kana mavanga kana kubuda ropa zviri nyore kupfuura zvakajairika.
• Kana ukaona madonhwe matsvuku madiki, ane pin-point paganda rako, aya anogona kunge ari petechiae, tsinga diki dzeropa dziri pasi peganda.
• Kana uchiwanzobatwa nezvirwere zvine fivha .

Chii chinokonzera MDS?

Zvinoita sekuti pane nzira mbiri huru dzekukura kweMDS. Imwe ndeyekuita zvimwe zvinhu zvinowedzera njodzi yekubatwa nechirwere ichi. Imwe ndeyekugara nhaka mamwe majini.

Mabasa anogona kusanganiswa neMDS

• Kana wakapihwa chemotherapy kana radiation therapy yekenza yawakambowana kare. Vanachiremba vanodana izvi kuti therapy-related MDS (tMDS). Kazhinji, zviratidzo zve tMDS zvinoonekwa makore mashanu kusvika manomwe mushure mekurapwa.
• Kusangana nezvimwe zvinhu zvinokonzera kenza, zvinosanganisira utsi hwefodya, mishonga yezvipembenene, uye zvinonyungudutsa zvakaita sebenzene.
• Kusangana nesimbi dzinorema dzakadai semercury kana lead.

Mamiriro ezvinhu enhaka anogona kunge akabatana neMDS

Pakati pe4% ne15% yevanhu vane chirwere ichi vane majini akatogara nhaka ayo anowedzera njodzi yavo yekubata chirwere ichi. Matambudziko akadaro anosanganisira:

• Fanconi anemia: Ichi chirwere chisingawanzoitika mumajini apo mupfupa wako haugadzi masero eropa ane hutano akakwana.
• Dyskeratosis congenita: Ichi chimwe chirwere chisingawanzoitiki chemajini. Pano zvakare, muro wemapfupa ako haugadzi masero eropa ane hutano akakwana.
• Diamond-Blackfan anemia: Ichi chirwere cheropa chisingawanzoitiki apo muromo wemapfupa haugadzi masero matsvuku eropa akakwana.

Chirwere chemyelodysplastic chinowanikwa sei?

Vanachiremba vanotevera matanho akati wandei ekuongorora chirwere ichi cheMDS:

• Kuverengwa Kweropa Kwakakwana (CBC) uye bvunzo yemhando dzakasiyana: Sample yeropa inotorwa kubva kwauri uye masero ako matsvuku nemachena anoongororwa. Inoverengawo huwandu hwerudzi rumwe nerumwe rwemasero machena eropa.
• Kuongororwa kweropa muropa: Izvi zvinoongorora shanduko muhukuru, mhando, chimiro, uye saizi yemasero eropa muropa rako, pamwe chete kana masero matsvuku eropa rako aine iron yakawandisa.
• Kuongororwa kweCytogenetic: Nyanzvi yezvirwere inotarisa ropa rakatorwa nemaikorosikopu kuti ione kana paine shanduko mumachromosome emasero eropa rako.
• Kuongororwa kwemapfupa emapfupa: Kuti aite bvunzo iyi, chiremba anoisa tsono isina chinhu mubhonzo rehudyu mako, otora sampuli yemapfupa emapfupa, ropa, nemapfupa, ozviongorora pasi pemaikorosikopu.

Ndezvipi zvikamu zve myelodysplastic syndrome?

Vanachiremba vanopatsanura chirwere ichi muzvikamu zvichienderana nenjodzi yekuti chirwere ichi chive acute myeloid leukemia (AML). Vanoshandisa nzira yekuongorora njodzi inonzi International Prognostic Scoring System (IPSS) . Heano mamwe maitiro avanachiremba vanofunga nezvawo:

• Ungave uine zviratidzo zvekushaya ropa, kubuda ropa, kana hutachiona.
• Uri panjodzi yekubatwa nechirwere cheleukemia.
• Kumwe kuchinja mumakromosomu ako.
• Ungave wakawana MDS mushure mekugamuchira chemotherapy kana radiation therapy yegomarara.
• Zera rako nehutano hwako.

Myelodysplastic syndrome inorapwa sei?

Vanachiremba vanofunga zvinhu zvakati wandei pavanenge vachironga kurapwa kweMDS:

• Rudzi rweMDS rwauinarwo.
• Ungave uine zvirwere zvakaita sekushaya ropa, kubuda ropa, kana hutachiona hunokonzerwa neMDS.
• Ungave wakawana MDS mushure mekugamuchira chemotherapy kana radiation therapy yegomarara.
• zera rako.
• Hutano hwako hwese.

Kurapa myelodysplastic syndrome kunogona kusanganisira rubatsiro rwekutsigira uye kurapwa kunoparadza masero eropa asina hutano .

Kutarisira Kunotsigira

Izvi zvinogona kusanganisira:

• Kuwedzerwa ropa kana kupa ropa: Kana uine anemia, unogona kuwedzerwa masero matsvuku eropa. Kana uine matambudziko ekubuda ropa, unogona kuwedzerwa platelet.
• Mishonga inosimudzira masero eropa (Erythropoiesis-stimulating agents) (ESA): Kurapa uku kunowedzera huwandu hwemasero matsvuku eropa akura.
• Mishonga inorwisa mabhakitiriya: MDS inogona kukanganisa masero machena eropa rako, zvichiwedzera njodzi yako yekubatwa nezvirwere. Saka, mishonga inorwisa mabhakitiriya inogona kupihwa.

Kurapa kubvisa masero eropa asina hutano

Izvi zvinogona kusanganisira:

• Kurapa nemakemikari: Mhando dzakafanana dzemishonga inoshandiswa pakurapa acute myeloid leukemia (AML) dzinogona kushandiswa pane izvi.
• Kurapa kwekudzivirira muviri: Kurapa uku kunoshandiswa kune mamwe marudzi eMDS. Kurapa uku kunoderedza kushanda kwemuviri zvakanyanya uye kunogona kubatsira kuderedza kudiwa kwekuwedzerwa ropa.
• Kuisirwa masero eropa: Izvi zvinosanganisira kutsiva masero ako anogadzira ropa nemasero eropa, kungave kubva kwauri kana kune anokupa. Masero aya anotorwa kubva muropa rako kana mumongo wemapfupa. Masero aya anochengetwa mufiriji paunenge uchigamuchira chemotherapy, obva anyungudika odzorerwa mumuviri wako kuburikidza nekuisirwa mutsinga. Masero aya anobvumirwa kukura mumuviri wako uye kugadzira masero matsva eropa.

Kurapa kwese uku kunogona kuva nemigumisiro yakasiyana uye matambudziko. Paunenge uchifunga nezvesarudzo dzekurapa, zvakakosha kubvunza chiremba wako nezvemigumisiro uye matambudziko enzira imwe neimwe.

Vanhu vane myelodysplasia vanogona kubatsirwa nekurapwa kwekuderedza kushushikana . Kurapwa uku kunogona kubatsira kudzora zviratidzo zveMDS nemigumisiro yekurapwa. Uye zvakakosha, kunogona kubatsira kudzora kushushikana kwekurarama nechirwere chisingaperi chakadaro.

Myelodysplastic syndrome inogona kurapwa here?

Nzira chete yekurapa MDS zvizere ndeyekuisirwa masero ekutanga . Zvinosuwisa kuti havasi vese vanogona kuwana kurapwa uku. Bvunza chiremba wako kana rudzi urwu rwekuisirwa rwakakunakira uye kana iri sarudzo yaunofanira kufunga nezvayo.

Munhu ane myelodysplastic syndrome anotarisira kurarama kwenguva yakareba sei?

Myelodysplastic syndrome idambudziko guru rehutano rinogona kukonzera matambudziko anotyisidzira hupenyu.Uyewo, iyi inyaya yehutano yakaoma zvikuru, uye munhu wese anobatwa nenzira dzakasiyana. Chiremba wako ndiye anonyanya kukupa ruzivo nezvemamiriro ako ezvinhu uye fungidziro yechirwere chako.

Myelodysplastic syndrome inogona kudzivirirwa here?

Kwete, asi kunzwisisa zvinhu zvinokonzera MDS kunogona kubatsira vanachiremba kuongorora nekurapa MDS nekukurumidza. Myelodysplastic syndrome inobatanidzwa ne chemotherapy ne radiation therapy, pamwe nekusangana nemamwe makemikari nesimbi dzinorema. Taura nachiremba wako nezvenhoroondo yako yezvekurapa uye chero kusangana kwako nemakemikari nesimbi dzinorema kwenguva refu. Vanogona kukubatsira kuongorora njodzi yako pachako.

Ndinozvitarisira sei?

MDS inobata munhu wese zvakasiyana. Vamwe vanhu vane MDS asi havana zviratidzo. Kana izvi zviri izvo kwauri, chiremba wako anogona kukurudzira kuongororwa ropa mwedzi mitatu yega yega kuti aongorore shanduko dziri mumasero ako eropa. Kana uine MDS uye uri kugamuchira rubatsiro rwekutsigira, senge kuwedzerwa ropa, ungangoda mamwe marapirwo ekuderedza kuwanda kwekuwedzerwa ropa. Heano mamwe matanho aunogona kutora kuti utsigire kurapwa kwako:

• Kana uchishandisa zvigadzirwa zvefodya (kusanganisira kuputa fodya uye kuputa fodya), edza kurega. Bvunza chiremba wako nezvezvirongwa zvekurega fodya.
• Ramba uine huremu hwakanaka.
• Tsvaga mitambo yekurovedza muviri yaunofarira uye ita kakawanda sezvinobvira.
• Yeuka kuti MDS chirwere chisingaperi, uye vanachiremba vanogona kuchirapa asi kwete kuchirapa. Havasi vese vanozonzwisisa zvauri kusangana nazvo. Kutaura nevamwe vakambosangana nezvinhu zvakafanana nezvaungabatsira. Chikwata chako chekurapa chinogona kukubatsira kuwana mapurogiramu nezvinhu zvakaita seizvi.

Kunyange hazvo MDS iri chirwere chisingaperi, hazvirevi kuti unofanira kurarama usina tariro. Kune mishonga inogona kubatsira kudzora chirwere ichi.

Ndinofanira kuenda kuchipatara riini?

Myelodysplastic syndrome inogona kukonzera kupererwa kweropa, matambudziko ekubuda ropa, uye hutachiona. Unofanira kuenda kuchipatara kana uine:

• Kana uine fivha inosvika 38.3 degrees Celsius (100.4 degrees Fahrenheit) kana kupfuura, fivha chiratidzo chekuti ungangove uine hutachiona.
• Kana uri kubuda ropa zvisingadzoreki.

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Nekuti myelodysplastic syndrome chirwere chisingawanzoitiki, ungave nemibvunzo yakawanda nezvacho. Heano mimwe mibvunzo yaunogona kubvunza chiremba wako:

• MDS igomarara here?
• MDS inondikanganisa sei?
• MDS yangu ichakonzera matambudziko makuru ehutano here? Kana zvakadaro, rudzii?
• Handina zviratidzo. Ndingaitei kuti ndinonotse kukura kwezvirwere zvine chekuita neMDS?

Mharidzo Yekupedzisira Yekuenda Kumba

Kana uine myelodysplastic syndrome (MDS), imhando yegomarara chirwere chisingaperi. Hapana chirwere chiri nyore, asi kurarama nechirwere chisingaperi zvinoreva kubata nekukanganiswa kwachinogona kuita mupfungwa. Asi kurarama neMDS hazvirevi kuti unofanira kurasa tariro. Kune mishonga inogona kubatsira kudzora MDS. Unogona kukodzera kuyedzwa kwekiriniki kuri kutsvaga mishonga mitsva yemyelodysplastic syndrome. Kunewo zvinhu zvaunogona kuzviitira. Bvunza chiremba wako nezvekuchinja mararamiro, zvakaita sekudya zvakanaka uye kurovedza muviri. Zvinhu izvi zvinogona kukubatsira kuti urambe uine hutano hwakanaka sezvinobvira. Usambofa wakatya, uye usatambura uri wega. Taura nachiremba wako nezvezvinhu zvese, uye uwane rubatsiro rwaunoda.

Myelodysplastic syndrome, MDS, myelodysplasia, kenza yeropa, muro wemapfupa, anemia, masero eropa