Une bundu mumutsipa wako here? Ngatikurukurei nezvePapillary Thyroid Cancer (PTC)!

Wakamboona bundu diki mumutsipa wako here? Kana kuti chiremba akambokuudza nezvaro panguva yekuongororwa? Dzimwe nguva bundu diki rakadai rinogona kuva chiratidzo chekutanga chechirwere chinonzi Papillary Thyroid Cancer (PTC). Usazvidya moyo, tichataura nezvazvo zvakadzama uye zviri nyore.

Chii chinonzi papillary thyroid carcinoma (PTC)? Chii chinonzi thyroid gland?

Zvichitaurwa zviri nyore, kenza yemudumbu (PTC) imhando yekenza inokura mugland redu re thyroid. Inotangira mumasero e follicular egland re thyroid. Masero aya anogadzira puroteni inonzi thyroglobulin . Chinhu chakakosha kuziva ndechekuti PTC ndiyo mhando yekenza ye thyroid yakajairika .

Zvino ngatitarisei kuti thyroid gland chii. Fungidzira, pamberi pemutsipa wako, pasi peganda, nhengo diki yakaita seshavishavi. Ndiyo thyroid gland. Ichi chikamu che endocrine system yedu. Basa rayo guru nderekugadzira nekuburitsa mahormone anodzora mabasa akawanda akakosha mumuviri wedu.

Kana tichitaura nezvePTC, kazhinji igomarara rinokura zvishoma nezvishoma . Uyewo, rinowanzo buda parutivi rumwe chete rwegland re thyroid.

Kune mhando dzakasiyana dze `PTC` here?

Ehe, kune mhando dzakasiyana-siyana dze `PTC`. Pamhando idzi, mhando ye follicular ndiyo inonyanya kuzivikanwa. Dzimwe nguva inonzi `mixed papillary-follicular variant`. Dzimwe mhando hadzina kufanana. Zvisinei, dzinogona kukura nekupararira nekukurumidza . Mhando dzakadai ndeidzi:

• `Koramu`
• `Sero refu`
• `Zviri mukati`
• 'Diffuse sclerosis'

Dzimwe nguva `PTC` inonziwo `papillary thyroid carcinoma` .

Ndiani anowana kenza ye thyroid ye papillary?

Kutaura zvazviri, PTC inogona kuitika kune chero munhu. Zvisinei, inonyanya kuitika kune vanhu vakuru vane makore epakati nepakati . Uyewo, vakadzi vane mukana wekuwana chirwere ichi kupfuura varume.

PTC chirwere chisingawanzoitiki muvana. Zvisinei, ndiyo mhando yegomarara rethyroid rinowanzoonekwa muvana.

Iyi `PTC` yakajairika zvakadii?

Gomarara rethyroid chirwere chinowanzoitika. Zvisinei, sezvatakambotaura, 80% kusvika 85% yevanhu vane chirwere ichi vane rudzi rwePTC. Izvi zvinoreva kuti vanhu vasere pavanhu gumi vanobatwa negomarara rethyroid vane rudzi urwu.

Ko `PTC` chirwere chakakomba here?

Kenza yerudzi rupi zvarwo yakakomba. Inoda kurapwa uye inogona kupararira (metastasize) kune dzimwe nhengo dzemuviri. Zvisinei, fungidziro yePTC yakanaka kwazvo kana tichienzanisa nedzimwe mhando dzekenza yethyroid.

Kazhinji, PTC inogona kurapwa zvinobudirira. Hazviwanzoitiki kuti iuraye. Saka, zvakakosha kuti usatye uye utevedzere mazano akakodzera ekurapa.

`PTC` inotanga kupararira kupi?

Kana PTC ikapararira, inogona kutanga yapararira kuma lymph nodes ari mumutsipa . Ma nodes aya madiki akaita sebhinzi ari chikamu che lymphatic system yemuviri wedu uye immune system.

`PTC` inopararira kusvika papi?

Kunyange zvazvo PTC ichikura zvishoma nezvishoma, inogona kupararira kusvika kuma lymph nodes ari mumutsipa. Zvichitaurwa zviri pachena, vanhu vanosvika 30% vane PTC vanenge vapararira kune dzimwe nzvimbo (metastatic papillary thyroid cancer) panguva yekuongororwa .

Ndezvipi zviratidzo zve `PTC`?

Kazhinji, chiratidzo chikuru chePTC kuoneka kwebundu risingarwadzi mugland re thyroid . Zvimwe zviratidzo zvinogonawo kusavapo.

Zvisinei, kashoma, vamwe vanhu vanogona kurwadziwa mumutsipa, shaya, kana nzeve . Kana bundu rikakura zvakakwana kuti ridzvanyirire pahuro kana pagurokuro, zvinogona kukonzera kufema kana kumedza kunetseka .

Zvakakosha: Kana ukaona bundu idzva mumutsipa wako, kunyangwe risingarwadzi, unofanira kuona chiremba. Kana ukariona nekukurumidza, ndipo panobva pabudirira kurapwa.

Ndezvipi zvikonzero zve `PTC`?

Masayendisiti haasati aziva chikonzero chaicho chePTC, asi vakaona zvinhu zvakawanda zvinogona kuwedzera njodzi yekuva nechirwere ichi, kusanganisira kuratidzwa nemwaranzi uye mamwe mamiriro ezvinhu emumajini .

Kuratidzwa nemwaranzi uye `PTC`

Vanhu vakambosangana nehuwandu hwakawanda hwemwaranzi ionizing munhoroondo yavo vane mukana mukuru wekuwana PTC. Nzira idzo mwaranzi iyi inogona kusangana nadzo ndeidzi:

• Kurapwa nemwaranzi yekunze kwakanyanya kunopihwa kumutsipa kurapa kenza kana zvimwe zvirwere zvisina kenza, kunyanya muhudiki.
• Kuratidzwa nemwaranzi kubva mutsaona dzemagetsi enyukireya. Semuenzaniso, mushure metsaona yenyukireya yeChernobyl muna 1986, huwandu hwevarwere vePTC munzvimbo dzakapoteredza hwakawedzera kubva pa3-fold kusvika pa75-fold.

Mamiriro ezvemajini uye `PTC`

Kune mamiriro akasiyana-siyana ezvirwere zvemajini (zvakagarwa nhaka) anobatanidzwa nePTC:

• Familyal Adenomatous Polyposis (FAP / Gardner syndrome): Ichi chirwere chisingawanzoitiki, chinogara nhaka. Chinokonzera kuti munhu ave nemapolyps akawanda muura hwake nemurectum, izvo zvinogona kuita kenza. Vanhu vane FAP vari panjodzi yakakura yekuva nemamota mune dzimwe nhengo dzemuviri, kusanganisira thyroid gland. Chirwere ichi chinokonzerwa nekuchinja kwemuto weAPC gene.
• Werner syndrome : Ichi chirwere chisingawanzoitiki. Chinoratidza zviratidzo zvekukwegura nekukurumidza (progeria). Vanhu vane Werner syndrome vari panjodzi yakakura yekuwana kenza. Rudzi rwakajairika ikenza yethyroid. Kuchinja kwakasiyana-siyana kunopfuura makumi masere mujini reWRN kwakawanikwa muvanhu vane chirwere ichi.
• Carney complex type 1 : Dambudziko iri rinowedzerawo njodzi yekuve nemarudzi akasiyana-siyana emabundu, kusanganisira mabundu ethyroid. Rinowanzo kukonzerwa nekuchinja kwemajini ePRKAR1A.

Zvisinei, zvinofanira kurangarirwa kuti 5% chete yevarwere vese vePTC vanobatanidzwa nematambudziko akadaro emajini.

Nzira yekuziva sei `PTC`?

Kazhinji, PTC inoonekwa sebundu riri mugland re thyroid. Ungangove wakazvinzwa iwe pachako, kana kuti chiremba angariwana panguva yekuongororwa kwemutsipa nguva dzose. Dzimwe nguva, bundu rinowanikwa netsaona panguva yekuongororwa kwechimwe chirwere.

Chiremba wako anogona kuraira bvunzo dzinotevera kuti aongorore PTC:

• Kuongororwa kwemifananidzo : Kuongororwa uku kunogona kubatsira kuona thyroid nodule. Semuenzaniso, thyroid ultrasound , CT scan , uye/kana MRI scan zvinogona kuitwa.
• Kusveta tsono netsono zvishoma (biopsy yetsono ): Chiremba anowanzo tora tsananguro diki yenyama (biopsy) kubva mugono re thyroid uchishandisa tsono yakatetepa zvikuru. Nyanzvi yezvirwere ichatarisa nyama nemaikorosikopu kuti ione kana paine masero ekenza uye, kana zvakadaro, rudzii rwekenza ye thyroid.

Dzimwe nguva, chiremba wako anogona kukutumira kuti uwane mazano ezvemajini kuti aone kana uine chirwere chemajini chinokonzera PTC, pamwe nemamwe marudzi emabundu.

PTC inorapwa sei?

Kurapwa kwePTC kunoenderana nehukuru hwebundu uye kana kenza yapararira.

Kuvhiya ndiyo nzira huru uye inonyanya kushandiswa yekurapa PTC.Zvichienderana nehukuru nenzvimbo yebundu, chiremba wako anogona kubvisa chikamu chegland re thyroid (lobectomy) kana gland rese (thyroidectomy). Kana kenza iri mumagland e thyroid, chiremba anogona kubvisa magland akakanganiswa panguva imwe chete nekuvhiyiwa kwegland re thyroid kana mukuvhiyiwa kwechipiri.

Zvakakosha: Kana gland rako rese re thyroid rikabviswa (kubviswa kwegland rese re thyroid), uchafanira kunwa mapiritsi e thyroid hormone kweupenyu hwako hwese .

Mamwe marapirwo ePTC ndeaya:

• Kurapa neRadioiodine : Masero ethyroid nePTC masero anotora mineral iodine (inowanikwa mune zvimwe zvekudya). Nekuda kweizvi, vanachiremba dzimwe nguva vanoshandisa radioactive form ye iodine kuparadza chero thyroid tishu yasara mushure mekunge thyroid gland yabviswa, pamwe nechero thyroid tishu yekenza inogona kusara.
• Kurapa nemwaranzi : Kurapa nemwaranzi kunouraya masero egomarara uye kunoamisa kukura. Mukurapa nemwaranzi yekunze, muchina unotungamidza mwenje yesimba ine simba zvakananga pagomarara. Mukurapa nemwaranzi yemukati, mbeu dzinoiswa mukati kana kutenderedza gomarara.
• Kurapa nemakemikari : Mishonga yemakemikari inopihwa netsinga (IV) kana nemuromo (nemuromo) inouraya masero ekenza uye inomisa kukura kwekenza. Zvisinei, vanhu vashoma chete vane kenza yethyroid vanoda chemotherapy.

Ndezvipi migumisiro nematambudziko ekurapwa kwe'PTC'?

Zvimwe zvinogona kuitika kana munhu abviswa thyroid uye abviswa radioiodine therapy imhaka yekuti thyroidectomy haishande zvachose. Saka, kana ukashandisa imwe yemishonga iyi kana yese, unofanira kunwa mapiritsi emahormone ethyroid kweupenyu hwako hwese.

Pane matambudziko akawanda anogona kuitika panguva yekuvhiyiwa kwe thyroid:

• Utachiona.
• Kubviswa netsaona kana kukuvara kweparathyroid glands , izvo zvinodzora huwandu hwecalcium muropa rako.
• Kukuvadzwa kwetsinga yegurokuro inodzokororwa, iyo inomhanya kuseri kwegland re thyroid. Izvi zvinogona kukonzera kuti inzwi rive rakashoshoma uye risina simba.

Migumisiro inogona kuitika yekurapwa ne radioactive iodine:

• Kusvotwa nekurutsa.
• Sialadenitis - kuzvimba kweganda remate.
• Thyrotoxicosis yenguva pfupi.
• Pulmonary fibrosis chirwere chinokonzera mavanga mumapapu.
• Kushaya mbereko kwenguva pfupi kana kuti zvachose.
• LeukemiaNjodzi diki yekubatwa neleukemia, kenza yemazamu, kana kenza yedundira.

`PTC` inogona kudzivirirwa here?

Vanhu vazhinji vanorwara negomarara rethyroid havana zvinhu zvinovaisa panjodzi. Saka, nyaya zhinji dzePTC hadzigone kudzivirirwa.

Kusangana nemwaranzi, kunyanya panguva yehudiki, chinhu chinozivikanwa chine njodzi yePTC. Nekuda kweizvi, vanachiremba havachashandisi mwaranzi pazvirwere zvisina kunyanya kuoma. Vana vanosanganawo nemwaranzi kubva mukuongororwa kwemifananidzo senge X-rays neCT scans, asi muhuwandu hwakaderera. Hazvizivikanwe kuti vanowedzera sei njodzi yePTC.

Kana mumwe munhu mumhuri mako akamborwara negomarara remudumbu, ungangoda kupiwa mazano ezvemajini. Izvi zvichakubatsira kuona kana uine chirwere chemajini chinokuisa panjodzi huru yekubatwa nechirwere chePTC. Kana ukadaro, chiremba wako anogona kukurudzira kuvhiyiwa kwekudzivirira kubvisa gomarara remudumbu rako risati ratanga.

Chii chinonzi fungidziro yePTC?

Kazhinji, fungidziro yePTC yakanaka kwazvo , kunyanya kana uri pasi pemakore makumi mana ekuberekwa uye bundu racho riri diki. PTC inogona kurapwa zvinobudirira. Kunyangwe kana yakapararira kusvika kuma lymph nodes mumutsipa, haiwanzo kuuraya.

Zvinhu zvinogona kuderedza mwero wekupora zvinosanganisira:

• Kuva nemakore anopfuura 55 ekuberekwa pakuongororwa chirwere.
• Bundu riri kukura .
• Kenza yapararira kusvika kunzvimbo dziri kure dzemuviri .
• Kuva nerudzi rusingawanzoitiki rwe'PTC' (semuenzaniso 'tall cell variant', 'diffuse sclerosis variant', 'solid variant').

Unogona kurarama `PTC` here?

Huwandu hwevanhu vane PTC vanorarama nechirwere ichi hwakakwira zvikuru . Vanhu vakuru vanopfuura 90% vane PTC vanorarama kwemakore angangoita gumi kusvika makumi maviri mushure mekurapwa.

Ndirini pandinofanira kuona chiremba nezve `PTC`?

Kana ukaonekwa uine PTC, uchafanirwa kusangana nechikwata chako chekurapa nguva nenguva kuti utarise kufambira mberi kwekurapwa kwako. Uchafanirwawo kuva nenguva refu yekutevera mushure memwedzi mitanhatu kusvika gumi nemiviri kweinenge makore mashanu kuti utarise kana chirwere chacho chichidzoka zvakare.

Kana thyroid gland yako yakabviswa uye/kana kurapwa ne radioactive iodine kwakapihwa sechikamu chekurapwa kwako, uchafanirwa kunwa mapiritsi e thyroid hormone kweupenyu hwako hwese . Chiremba achaongorora huwandu hwe thyroid hormone yako muhupenyu hwako hwese kuti ave nechokwadi chekuti mushonga wako wakakunakira.

Kuonekwa uine kenza, zvisinei nerudzi rwechirwere, kunogona kushamisa. Zvisinei, mashoko akanaka ndeekuti fungidziro yePTC inowanzova yakanaka kwazvo. Chikwata chako chekurapa chichashanda newe kuti chisarudze nzira yakanakisa yekurapa.

## Zvinhu zvakakosha zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, saka, kubva pane zvatataura nezvazvo, izvi ndizvo zvinhu zvakakosha zvaunofanira kurangarira:

• Kenza yethyroid yePapillary (PTC) ndiyo mhando yekenza yethyroid yakajairika uye ine fungidziro yakanakisisa.
• Chiratidzo chikuru ibundu risingarwadzi mumutsipa. Kana ukaona chimwe chinhu chakadai, bvunza chiremba.
• Kuvhiyiwa ndiwo mushonga mukuru. Kurapa ne radioactive iodine kunogonawo kudiwa.
• Kana thyroid gland ikabviswa zvachose, uchafanira kutora mahormone ethyroid kweupenyu hwako hwese .
• Kana chirwere ichi chikaonekwa nekukurumidza, kurapwa kwacho kunobudirira zvikuru. Saka, kugara uchiongororwa nachiremba uye kutevedzera mazano kwakakosha zvikuru.
• Usatya. Hausi wega. Kune vanachiremba, mhuri, neshamwari kuti vakubatsire.

Ndinovimba ruzivo urwu ruchakubatsira. Kana uine mibvunzo, usazeza kubvunza chiremba wako. Ramba uine hutano hwakanaka!

Gomarara re thyroid , kenza ye thyroid yepapillary, PTC, mapundu emutsipa, kuvhiyiwa kwe thyroid, kurapwa nemwaranzi, kurapwa nemahormone