Kana chiremba akakuudza iwe kana mumwe munhu waunoda kuti une "kenza yemazamu ," zvakajairika kunzwa sekunge nyika yako yese yadonha. Pamwe chete nekutya nekuzvidya mwoyo zvinouya mupfungwa, unewo mibvunzo yakawanda nezvekurapa nemishonga inonyorerwa nachiremba. "Mushonga uyu wakanaka here mumuviri?", "Uchakonzera migumisiro yakaipa here?", "Izvi zvichashanda zvechokwadi here?" Zvinhu zvakadaro zvingangove zvichimhanya mumusoro mako. Ndizvo zvatichataura nezveTamoxifen, mushonga unokosha zvikuru unoshandiswa zvakanyanya mukurapa kenza yemazamu, nenzira iri nyore uye ine hushamwari nhasi.
Zvichitaurwa zviri nyore, chii chinonzi Tamoxifen?
Tamoxifen mushonga unoshandiswa kurapa kenza yemazamu ine hormone receptor-positive . Unouya sepiritsi (Nolvadex®) kana mvura (Soltamox®).
Zvino ungave uchifunga kuti, "Konza iyi inokonzerwa nemahormone chii?" Zviri nyore kwazvo. Mamwe masero ekenza mumuviri wedu akafanana nemuti mudiki. Kungofanana nemuti unoda mvura nekudya kuti ukure nekukura, masero aya ekenza anoda mahormone anonzi estrogen kana progesterone kuti akure nekupararira. Ndizvo zvatinodaidza kuti 'kenza inokonzerwa nemahormone.'
Zvinoitwa nemushonga we tamoxifen zvinodzivirira kushanda kwehormone yeestrogen inodiwa nemasero ekenza. Zvakafanana nekudzima pombi yemvura yemuti. Ipapo masero ekenza haanzwisisi zvaanoda kuti akure.
Uyewo, vanachiremba dzimwe nguva vanokurudzira mushonga uyu kudzivirira kenza kuvanhu vari panjodzi huru yekubatwa nekenza yemazamu (semuenzaniso, kana mumwe munhu mumhuri akambobatwa nekenza ).
Mushonga uyu unokurudzirwa kushandisirwa ani?
Tamoxifen haipiwi varwere vese vane kenza yemazamu. Chiremba wako achafunga nezvezvinhu zvakawanda, kusanganisira nhoroondo yako yehutano uye rudzi rwekenza, kuti asarudze kana mushonga uyu wakakunakira. Unonyanya kushandiswa muzviitiko zvinotevera:
- Avo vane nhoroondo yemhuri yekenza kana shanduko dzemajini eBRCASenzira yekudzivirira gomarara kune avo vari panjodzi huru yekubatwa negomarara remazamu nekuda kwezvinhu zvakaita se:
- Kudzivirira kudzoka kwekenza kumunhu akamborwara nekenza yemazamu uye akamborapwa zvakadai sekuvhiyiwa , chemotherapy , kana radiation therapy .
- Dzivirira kenza mune rimwe zamu rine hutano kune mumwe munhu ane kenza mune rimwe zamu.
- Kune munhu ane kenza iri padanho rekutanga, senge DCIS (ductal carcinoma in situ) , dzivirira kuti isapararire zvakanyanya uye ive kenza yakakomba.
Chinhu chinonyanya kukosha ndechekuti sarudzo yekuti mushonga uyu wotora here kana kuti kwete, uye kuti uchatora kwenguva yakareba sei, inofanira kuitwa nachiremba wako chete. Saka usatya kukurukura chero mibvunzo yaunayo nezveizvi nachiremba wako.
Ndezvipi zvakanakira zvikuru zveTamoxifen?
Tamoxifen mushonga wakabatsira kuponesa mamiriyoni evakadzi pasi rose kwemakumi emakore. Mabhenefiti eizvi haasi mashoma.
- Inoderedza kudzoka kwegomarara: Mushonga uyu unogona kuderedza njodzi yekudzoka kwegomarara mushure mekurapwa ne30% kusvika 50% .
- Inodzivirira zamu rechipiri: Kune munhu akambova nekenza mune rimwe zamu, njodzi yekubatwa nekenza mune rimwe zamu inoderedzwa neinenge 50% .
- Inodzivirira kenza: Kune munhu ari panjodzi huru, njodzi yekubatwa nekenza pakutanga inogona kuderedzwa neinenge 40% .
- Inosimbisa mapfupa: Mushonga uyu unobatsira kudzivirira osteoporosis , chirwere chekutetepa kwemapfupa chinoitika kunyanya mushure mekuguma kuenda kumwedzi.
- Inoderedza cholesterol: Tamoxifen ine simba rekuderedza huwandu hwecholesterol yakaipa mumuviri.
Ndezvipi zvimwe zvingakonzera migumisiro yekutora Tamoxifen?
Kufanana nemushonga upi zvawo, Tamoxifen inogona kukonzera mimwe migumisiro. Asi izvi hazvirevi kuti uchasangana nayo yese. Vamwe vanhu vangasanzwa zvachose. Vamwe vangasangana neimwe kana mbiri. Kuziva zvinhu izvi pachine nguva kuchakubatsira kurarama nazvo.
Ngatikamurai migumisiro iyi kuita zvikamu zviviri.
| Rudzi rwemhedzisiro yakaipa | Tsananguro |
|---|---|
| Migumisiro yakajairika, isina kunyanya kuipa | |
| Zviratidzo zveKuenda Kumwedzi | Kupisa, kudikitira husiku, uye kuoma kwechikadzi ndezvimwe zvezvinhu zvinonyanya kushungurudza vanhu vazhinji. |
| Kuchinja kwekuenda kumwedzi pamwedzi | Kuenda kumwedzi kunogona kutadza kurongeka kana kumira zvachose. |
| Kuwedzera huremu kana kuzvimba | Vamwe vanhu vanogona kuwedzera huremu. Vamwe vanogona kuzvimba (edema) sekunge muviri wavo wazara nemvura. |
| Zvimwe zvidiki zvinokanganisa | Kubuda kwetsvina munhengo yekubereka, kuda kurutsa, mapundu paganda, kuneta, musoro, kuzvimba kwemakumbo, uye kusashanda zvakanaka kwenhengo dzekubereka muvarume zvinogona kuitika. |
| Njodzi dzisingawanzoitiki asi dzakakomba | |
| Kugwamba kweropa | Pane mukana mudiki wekuva nematambudziko akadai sekugwamba kweropa mutsinga dzemakumbo (deep vein thrombosis - DVT) kana sitiroko. |
| Kenza yechibereko | Tamoxifen inowedzera zvishoma njodzi yekenza yechibereko, inova jira riri mukati mechibereko. Ndosaka uchifanira kuudza chiremba wako nekukasika kana ukaona kubuda ropa kusingawanzoitiki muchizvaro. |
| Matambudziko emaziso | Njodzi yekubatwa nekatarakita inogona kuwedzera zvishoma. |
Zvakakosha kuyeuka kuti migumisiro iyi yakaipa haiwanzoitiki , asi kuchenjera kuiziva uye kuzivisa chiremba wako nekukasika kana paine chimwe chezviratidzo izvi chikaitika.
Ndinguva ipi yaunofanira kufonera chiremba nekukurumidza?
Kana uri kutora Tamoxifen uye ukaona chimwe chezviratidzo zvinotevera, unofanira kuzivisa chiremba wako nekukasika kana kuenda kuEmergency Department (ETU) yechipatara chiri pedyo newe.
- Kana uchinzwa kurwadziwa muchipfuva kana kufema zvakaoma .
- Kana ukanzwa fivha .
- Kana uine zviratidzo zvestroke - semuenzaniso, kutaura kusina kunyatsojeka, kuona zvisizvo, kana kuti kunzwa kusanzwa zvakanaka kamwe kamwe kune rumwe rutivi rwemuviri (ruoko, gumbo, kana kumeso).
- Kana makumbo ako, zvitsitsinho, kana tsoka zvikazvimba kamwe kamwe (kunyanya gumbo rimwe chete).
- Kana usingakwanise kurega kurutsa .
- Kana uine kubuda ropa kusingawanzoitiki kubva muchibereko .
Mimwe mibvunzo inowanzo bvunzwa nezveTamoxifen
Tamoxifen imishonga yekurapa chemotherapy here?
Kwete. Apa ndipo panovhiringidzika vanhu vazhinji. Tamoxifen mushonga wemahormone . Ndewemhando yemishonga inonzi Selective Estrogen Receptor Modulators (SERMs) . Chemotherapy mushonga unouraya masero anokamura nekukurumidza (masero ekenza pamwe nemasero ane hutano). Asi Tamoxifen inoshanda nenzira yakasiyana, padanho remahormone.
Zvinokwanisika here kutora Tamoxifen panguva yekuzvitakura?
Kwete zvachose. Kubata pamuviri paunenge uchitora tamoxifen kunogona kukonzera matambudziko makuru ekuzvarwa . Saka kana uri kutora mushonga uyu, unofanira kudzivirira kubata pamuviri . Kudzivirira pamuviri kwemahormone (senge mapiritsi ekudzivirira pamuviri) hakukodzeri panguva ino, saka taura nachiremba wako nezvekushandisa nzira yekudzivirira pamuviri isiri yemahormone (senge makondomu kana maIUD). Zvakakosha kushandisa nzira yekudzivirira pamuviri kwemwedzi miviri mushure mekumira kushandisa mushonga.
Ndezvipi zvekudya nezvinwiwa zvaunofanira kurega paunenge uchitora Tamoxifen?
Ehe. Zvimwe zvekudya nezvinwiwa zvinogona kuderedza kushanda kweTamoxifen. Saka, zvakanaka kudzivirira izvi:
- Muchero weGrapefruit
- Matangerine
- Doro remhando ipi zvayo
Migumisiro yakaipa inoitika pakarepo mushure mekutanga kutora mushonga here?
Izvi zvinosiyana kubva pamunhu nemunhu. Vamwe vanhu vanogona kutanga kuona shanduko diki kubva pazuva ravakatora piritsi rekutanga. Vamwe vanogona kusaona chero chinhu kwemwedzi yakati wandei.
Mushonga uyu unogara mumuviri kwenguva yakareba sei mushure mekumira?
Tamoxifen inoramba ichishanda mumuviri kwemavhiki maviri mushure mekunge watora piritsi rekupedzisira, asi zvinogona kutora mwedzi mitatu kuti ibude zvachose mumuviri wako.
Mharidzo Yekuenda Nayo Kumba
- Tamoxifen mushonga unoshanda zvikuru wekurapa kenza yemazamu inokonzerwa nemahormone.
- Mushonga uyu unoderedza zvakanyanya njodzi yekudzoka kwekenza uye kukura kutsva.
- Usazvidya mwoyo nezvemigumisiro yemishonga. Mizhinji yacho inogona kugadziriswa. Asi ziva zviratidzo zvakakomba uye taurira chiremba wako nekukurumidza kana zvikaitika.
- Zvakakosha kuti urambe uchitora mushonga uyu kwenguva yese yawakanyorerwa nachiremba wako.
- Sunungukai kukurukura chero mibvunzo kana zvinokunetsai nachiremba wenyu. Ikodzero yenyu.
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