Zvakaoma kutaura zvaunonzwa paunoziva kuti une kenza. Asi kana chiremba akataura nezvekurapa uye ukanzwa mazwi akadai sekuti 'chemotherapy', zvakajairika kuti unzwe kutya, kuda kuziva, uye kuvhiringidzika. Imwe yemishonga yekemo inonyanya kushandiswa pakurapa kenza i'Taxane.' Nhasi, tichataura nezvazvo zviri nyore, nenzira yaunogona kunzwisisa, sekunge uri kutaura neshamwari yepedyo.
Chii chaizvo chinonzi Taxane?
Zvichitaurwa zviri nyore, taxanes imhando yemishonga yechemotherapy inouraya masero ekenza uye inomisa kukura kwemabundu. Chemotherapy inosanganisira kuwedzera mishonga iyi muropa redu, iyo inofamba mumuviri wese kuti iwane uye iparadze masero ekenza.
Chinoita kuti mishonga iyi yetaxane ive yakasiyana ndechekuti inobva mumiti. Yakatanga yatorwa kubva mumuti we'Yew' . Kutaura zvazviri, taxanes ndeimwe yemhando mbiri dzemishonga yechemo inobva mumiti. Imwe mhando iboka remishonga inonzi 'Vinca alkaloids', iyo inobva mumuti we'Mella'.
Mazuva ano, masayendisiti ari kudzidza nezvemagadzirirwo emakemikoro etaxanes anowanikwa kubva mumiti iyi uye ari kutoshanda kuti agadzire mumarabhoritari.
Mushonga uyu unouraya sei masero egomarara?
Kuti tinzwisise izvi, tinofanira kutanga tanzwisisa kuti masero ekenza anopararira sei. Gomarara rinopararira nekukamura sero rimwe regomarara kuita maviri, iro rinozokamura kuita mana, rozowanda nekukurumidza. Mukurapa, maitiro ayo sero rinokamura kuita maviri anonzi mitosis .
Zvinoitwa nemishonga yetaxane zvinokanganisa maitiro ekupatsanurwa kwemasero.
Fungidzira kuti kana sero rikapatsanuka, majini ari mukati mesero iroro anofanira kupatsanurwa kuita maviri chaiwo otumirwa kumasero maviri matsva. Kune maumbirwo ari mukati mesero anobatsira pabasa iri, setambo diki. Izvi zvinonzi ma microtubules . Izvi ndizvo zvinokwevera zvikamu zvinodiwa kumasero maviri matsva.
Kana mushonga wetaxane ukatorwa mumuviri, unoita kuti tambo idzi dzinonzi microtubules dziome zvisina kufanira . Zvadaro hadzikwanise kupetwa kana kuvhurwa zvakanaka. Saka, maitiro ekupatsanura sero kuita maviri anomira pakati. Kana kupatsanura uku kusingagone kuitwa, sero remubereki rinofa mushure mechinguva.
Mishonga yeTaxane inodzora kenza nekuparadza kugona kwemasero ekenza kupatsanurana nekukura.
Mishonga yegomarara inoshandiswa pamhando dzipi?
Mishonga yeTaxanes imhando yakakosha yemishonga inoshandiswa kurapa mhando dzakasiyana dzekenza. Mimwe yemishonga iyi inoshandiswa senzira yekutanga yekurapa dzimwe kenza, nepo mimwe inoshandiswa kune kenza dzakapararira.
| Mhando dzegomarara dzinorapwa neTaxane | |
|---|---|
| Gomarara rinoshandiswa zvakanyanya | |
| Kenza yemudumbu | Kenza yemazamu |
| Mamwe marudzi egomarara anorapwa | |
| Kenza yedundira | Kenza yemumuromo wechibereko |
| Kenza yemudumbu | Kenza yemusoro nemutsipa |
| Kenza yeprostate | Kenza yemapapu (Kenza yemapapu isiri masero madiki) |
| Kenza yechibereko | Lymphoma |
Mune zvimwe zviitiko, taxanes inopihwa pamwe chete nemimwe mishonga yechemotherapy. Chiremba wako ndiye achasarudza kuti ndeipi mishonga yakanakira chirwere chako.
Kurapwa uku kunopiwa sei? Uye ndeapi migumisiro yakaipa?
Maitirwo ekurapwa
Taxanes inopihwa netsinga (IV) . Inopihwa kuburikidza ne cannula (catheter), yakafanana ne saline solution. Kurapa uku kunogona kutora awa imwe kana maawa akati wandei. Ungangoda kurapwa uku kamwe chete pasvondo, kana kamwe chete pamavhiki mashoma. Chiremba wako ndiye achasarudza nguva yekurapwa zvichienderana nemamiriro ako ezvinhu.
Migumisiro inowanzoonekwa
Kunyange hazvo mishonga yechemotherapy ichinyanya kupatsanura masero egomarara nekukurumidza, dzimwe nguva inogona kukanganisawo masero ane hutano, anopatsanura nekukurumidza mumiviri yedu. Semuenzaniso, zvinhu zvakaita semasero edu ebvudzi, masero eganda, uye masero eropa. Ndosaka migumisiro yakaipa ichiitika.
| Mhedzisiro Yepadivi | Tsananguro iri nyore |
|---|---|
| Neutropenia | Kuderera kwehuwandu hwema neutrophils, rudzi rwemasero machena eropa anorwisa hutachiona mumuviri, izvo zvinowedzera njodzi yekubatwa nehutachiona. |
| Neuropathy yemudumbu | Kukuvadzwa kwetsinga mumaoko nemakumbo. Izvi zvinogona kukonzera kusanzwa, kurwadziwa, kana kushaya simba mumaoko nemakumbo . |
| Kudonha kwebvudzi | Izvi zvinowanzokonzera migumisiro yakaipa, asi bvudzi rinokura zvakare mushure mekunge kurapwa kwapera. |
| Kurutsa uye kuda kurutsa | Zvinoitika kakawanda panguva yekurapwa. Mishonga inopihwa kudzora izvi. |
| Kurwadziwa kwetsandanyama nemajoini | Panogona kuva nekurwadziwa mumuviri uye kuomarara kwemajoini. |
| Kuchinja kweropa | Kumanikidzwa kweropa kunogona kukwira kana kudzika. |
| Kuderera kwemasero eropa | Kuderera kwemasero matsvuku eropa kunogona kukonzera anemia uye kudzikira kwemaplatelet (thrombocytopenia) kunogona kukonzera njodzi yekubuda ropa. |
Migumisiro iyi haiitike kune wese munhu. Zvakare, mizhinji yacho inogona kudzorwa. Zvakakosha kuzivisa chiremba wako kana vashandi vekuchengeta varwere nezvekusagadzikana kwaunonzwa.
Pane njodzi dziripo here pakurapwa uku?
Mishonga yeTaxanes inoshanda zvikuru uye yakawedzera hupenyu hwevarwere vegomarara. Zvisinei, sekurapa kwese, kune dzimwe njodzi.
Dzimwe nguva, migumisiro yakaipa yataurwa pamusoro apa inogona kuva yakakomba. Muzviitiko zvakadaro, chiremba wako anogona kusarudza kuchinja purogiramu yako yekurapwa kana kuimisa kwenguva pfupi.
Chimwe chinhu chakakosha ndechekuti nekufamba kwenguva, masero egomarara anogona kutanga 'kujaira' mushonga uyu. Kureva kuti, anotanga kuramba mishonga . Zvadaro simba remushonga uyu rinogona kudzikira. Asi kana izvozvo zvikaitika, chiremba wako achashandisa nzira dzakadai sekuyedza musanganiswa wemushonga wakasiyana kana kukurudzira nzira yakasiyana yekurapa.
Mharidzo Yekuenda Nayo Kumba
- Taxane iboka rine simba remishonga yechemotherapy inobva mumiti inomisa masero ekenza kuti asapatsanuke.
- Izvi zvinobudirira kurapa mhando dzakawanda dzegomarara, kusanganisira rezasi, remazamu, neremapapu.
- Migumisiro yakadai sekudonha kwebvudzi, kusanzwa kunzwa, uye kurwadziwa kwemuviri zvinogona kuitika, asi mizhinji yacho inogona kudzorwa.
- Zvakakosha zvikuru kuudza chiremba wako kana mukoti nezve chero kusanzwa zvakanaka kwaunonzwa panguva yekurapwa.
- Kurapwa kwegomarara rwendo. Gara uchiyeuka kuti hausi wega parwendo urwu uye kuti une timu yevanachiremba vane hunyanzvi kuti vakubatsire.
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