Ingaba kukho into engalunganga entliziyweni? Masifunde ngovavanyo lweTroponin.

Ngaba wakha weva ngovavanyo lweTroponin ? Mhlawumbi ukhe waya esibhedlele ngequbuliso esifubeni waza ugqirha wakho walwenza olu vavanyo. Okanye mhlawumbi ukhe walwenza kumhlobo wakho. Luyintoni kanye kanye uvavanyo lweTroponin? Makhe sithethe ngalo ngokufutshane.

Yintoni iTroponin? Kutheni ibalulekile?

Kulungile, masiqale sijonge ukuba yintoni le troponin. I-Troponin luhlobo lweproteni. Ukuchaneka, yiproteni ekhethekileyo engaphakathi kwiiseli zethu zemisipha yentliziyo. Ngokwesiqhelo, le troponin inamathele kwiiseli zemisipha yentliziyo. Kukho inani elincinci kakhulu layo egazini lethu, ngamanye amaxesha lincinci kangangokuba alibonakali.

Kodwa, khawucinge ukuba kukho into eyenzekayo entliziyweni, umzekelo , ukuba kukho into efana nokuhlaselwa yintliziyo, iiseli zemisipha yentliziyo zonakele. Emva koko i-troponin ebivaleleke ngaphakathi kwezo seli iqala ukuvuza egazini. Kufana nokuba i-Band-Aid iphuma, umxholo uyaphuma. Ngoko ke, ukunyuka kwenqanaba le-troponin egazini luphawu oluhle lokuba kukho umonakalo othile entliziyweni. Ngokuxhomekeke ekubeni inqanaba le-troponin liphezulu kangakanani, oogqirha banokufumana umbono wobungakanani bomonakalo entliziyweni.

Kukho iintlobo ezimbini ze-troponin, akunjalo?

Ewe, uchanekile. Kukho iintlobo ezimbini ze-troponins esinokuzifumana egazini, ingakumbi xa intliziyo yonakele. Nazi:

• I-Troponin I (iTroponin I okanye i-cTnI): Le ikhethekile kakhulu kuba olu hlobo lwe-troponin lufumaneka kuphela kwimisipha yentliziyo. Ke ngoko, ibaluleke kakhulu ekufumaneni iingxaki zentliziyo.
• I-Troponin T (iTroponin T okanye i-cTnT): Olu hlobo lwe-troponin lunokufumaneka ngobuninzi obuncinci kakhulu kwezinye izihlunu. Nangona kunjalo, ulwakhiwo lwe-troponin T entliziyweni lwahlukile kancinci. Loo mahluko usentliziyweni kuphela.

Uvavanyo olutsha lwe-troponin lunobuthathaka ngakumbi kuneemviwo zangaphambili. Oku kuthetha ukuba lunokubona nokuba yi -troponin encinci kakhulu egazini. Olu vavanyo lunokunceda ekuchongeni into efana nokuhlaselwa yintliziyo ngokukhawuleza, nokuba iimpawu azicacanga okanye ezinye iimvavanyo azikwazi ukuqiniseka.

Olu vavanyo lwe-troponin lwenziwa nini?

Amaxesha amaninzi, olu vavanyo lwe-troponin lwenziwa ukuqinisekisa ukuba kukho uhlaselo lwentliziyo okanye akunjalo . Nangona kunjalo, le troponin inokukhululwa egazini xa kukho umonakalo kwimisipha yentliziyo. Ke ngoko, oogqirha banokwenza olu vavanyo ngezinye izizathu.

Nazi ezinye iimeko ezinjalo:

• Isifo sezintso esingapheliyo`) Kwabo baye bakwenza oko.
• Ukuqhekeka kwegazi emiphungeni (i-pulmonary embolism).
• Kwabo bane-'Congestive heart failure' , uhlobo olubi lwesifo sentliziyo.
• Emva kotyando lwentliziyo.
• Kwabo banezifo zevalvu yentliziyo.
• Kwabo banentliziyo engaqhelekanga (`Arrhythmias`).
• Kwi-'Sepsis', usulelo olunzima oluye lwasasazeka emzimbeni wonke.
• Ngamanye amaxesha, ukuba uqhelisela umzimba ngokugqithisileyo, okanye ukuba ufumana uxinzelelo olungapheliyo okanye usizi.

Khumbula, nokuba amanqanaba e-troponin aphakanyisiwe kolu vavanyo, akuthethi ukuba uhlala unesifo sentliziyo. Oogqirha baza kwenza uvavanyo oluthe kratya ukuze bafumane unobangela.

Ndingenza njani olu vavanyo? Phi?

Olu vavanyo lwe-troponin ludla ngokwenziwa kwigumbi likaxakeka esibhedlele . Ukuba uneempawu zokuhlaselwa yintliziyo, ezinje ngeentlungu zesifuba okanye ukuphefumla kancinci, oogqirha baya kuyijonga ngokukhawuleza. Kwakhona, ukuba sele usesibhedlele, olu vavanyo lungasetyenziselwa ukujonga omnye umonakalo wentliziyo.

Oku kwenziwa ngokulula kakhulu. Isampuli yegazi ithathwa kuwe. Amaxesha amaninzi, kuthathwa igazi elincinci kumthambo osengalweni yakho. Emva koko loo sampuli yegazi ithunyelwa kwilabhoratri kwaye inqanaba le-troponin liyajongwa.

Ukuba amanqanaba e-troponin aphezulu kunesiqhelo, oko kubonisa ukuba izihlunu zentliziyo zonakele. Olu vavanyo, kunye nezinye iimvavanyo (ezifana ne-ECG), zezona zisetyenziswa ngoogqirha ukufumanisa ukuba kukho uhlaselo lwentliziyo.

Ngamanye amaxesha olu vavanyo luphindaphindwa rhoqo emva kweeyure ezimbalwa. Isizathu kukuba ngokujonga indlela inqanaba le-troponin elitshintsha ngayo ngokuhamba kwexesha, linokubonelela ngolwazi oluthe kratya malunga nobungakanani bomonakalo kunye nohlobo lwesifo. Umzekelo, amanqanaba e-troponin adla ngokuqala ukunyuka ngokukhawuleza phakathi kweeyure ezi-3 ukuya kwezili-12 emva kokuhlaselwa yintliziyo. Afikelela kwincopho malunga neeyure ezingama-24 kamva. Amanqanaba e-Troponin I (cTnI) anokuhlala ephakanyisiwe kangangeentsuku ezimbalwa emva koko (malunga neentsuku ezi-5-7). Amanqanaba e-Troponin T (cTnT) anokuhlala ephakanyisiwe ixesha elide, ukuya kuthi ga kwiiveki ezintathu. Ngenxa yokuba uvavanyo olutsha, olunobukrelekrele obuphezulu lunokufumanisa i-troponin T, edla ngokufumaneka egazini, oogqirha bayaluphinda uvavanyo ukuze babone ukuba amanqanaba e-troponin anyukile na. Ukuba bayakwenza oko, kubonisa ukuba imisipha yentliziyo yonakele.

Ngaba kufuneka ndilungiselele olu vavanyo? Ndimele ndilindele ntoni?

Asinakwazi ngokwenene kwaye sizilungiselele ukuhlaselwa yintliziyo kwangaphambili. Ngoko ke akukho mfuneko yokulungiselela olu vavanyo. Nangona kunjalo, kukho into ebaluleke kakhulu ekufuneka uyixelele ugqirha wakho.

Ukuba uthatha i-vitamin B7, ekwaziwa ngokuba yi-biotin, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngayo kunye nomthamo owuthathayo. Oku kungenxa yokuba i-biotin inokuchaphazela iziphumo zovavanyo lwe-troponin. Ngokuxhomekeke kubungakanani be-biotin oyithathayo, kungathatha iiyure ezininzi ukuba umphumo uphele.

Amaxesha amaninzi, xa kurhanelwa ukuba kukho isifo sentliziyo, oogqirha baqala ukukunika amayeza afunekayo ngokusekelwe kwiimpawu zakho kunye nezinye iimvavanyo (ezifana ne-ECG ) endaweni yokulinda ingxelo yovavanyo lwe-troponin. Kuba umzuzwana ngamnye ubalwa ngexesha lokuhlaselwa sisifo sentliziyo. Ukuba amanqanaba akho e-troponin akanyukanga kwiiyure ezili-12 emva kweziphumo zakho ze-troponin, oogqirha bakho baya kulungisa unyango lwakho ngokufanelekileyo.

Uziva njani ngexesha lovavanyo?

Oku kuquka ukuthatha igazi elincinci. Ngoko ke, umntu oqeqeshiweyo (ingcali ye-phlebotomist okanye umongikazi) uza kufaka inaliti encinci emthanjeni osengalweni yakho aze atsale igazi elincinci kwityhubhu enye okanye ezingaphezulu zovavanyo. Ukuba sele unomgca we-IV emthanjeni wakho, ungathatha nesampulu yegazi kuloo nto. Uza kuziva urhawuzelelwa kancinci xa inaliti ifakwa. Ngaphandle koko, akukho nto ingako ekufuneka uyixhalabele.

Kuthatha ixesha elingakanani ukwazi iziphumo?

Ingxelo yovavanyo idla ngokubuya emva kweyure enye okanye ezimbini. Xa ifikile, ugqirha wakho uza kukufowunela ukuze axoxe ngeziphumo kunye nokuba zithetha ukuthini. Abanye abantu banokufuna iimvavanyo ezingaphezulu okanye baqhubeke nokufumana unyango esibhedlele. Abanye basenokuba baphilile ngokwaneleyo ukuba bagoduke. Okwenzekayo emva koko kuyahluka kumntu nomntu, ngoko ugqirha wakho uza kukuchazela oku.

Ngaba kukho naziphi na iziphumo ebezingalindelekanga ezivela kolu vavanyo?

Uninzi lwexesha, akukho ziphumo zimbi kakhulu ezivela kolu vavanyo. Indawo apho igazi litsalwa khona inokuba buhlungu kancinci, yiyo loo nto kuphela. Abanye abantu, ingakumbi abo bakrweleka lula, banokufumana ikrweleka elincinci. Kodwa oku kuza kuphela emva kweentsuku ezimbalwa.

Zithini iziphumo endizifumanayo? Zithetha ukuthini?

Ukuba iziphumo zakho ze-troponin zingaphakathi 'koluhlu lwereferensi', oko kuthetha ukuba olwakho lungaphakathi koluhlu olufanele ukuba lulo umntu ophilileyo. Nangona kunjalo, olu luhlu luqhelekileyo lunokwahluka kancinci ngokuxhomekeke ekubeni ufumana phi uvavanyo kunye nohlobo lovavanyo olusetyenzisiweyo.

Amaxabiso aqhelekileyo ovavanyo lwe-troponin

Amanqanaba e-troponin egazini lomntu omdala ophilileyo aphantsi kakhulu, ngamanye amaxesha awabonakali. Xa amanqanaba e-troponin enyuka ngaphezu kolu luhlu luqhelekileyo, oko kuthetha ukuba i-troponin ivuza egazini evela kwiiseli zemisipha yentliziyo ezonakeleyo.

Umlinganiselo osetyenziswa ngoogqirha yi-nanograms nge-milliliter (`ng/mL`). Ngoko ke, amaxabiso aqhelekileyo ngala alandelayo:

• I-Troponin I: 0 - 0.04 ng/mL
• I-Troponin T: 0 - 0.01 ng/mL

Khawuthelekelele, i-nanogram yi-1 billionth yegram!Isixa esincinci kakhulu. I-millilitre yi-1000 yelitha. Ezinye iilabhoratri zisebenzisa iiyunithi ezibizwa ngokuba zii-micrograms (`mcg` okanye `mcg` - i-1000 yegram) okanye ii-picograms (`pg` - i-1 trillionth yegram). Ukuba unemibuzo malunga neziphumo okanye iiyunithi, ungathandabuzi ukubuza ugqirha wakho ingcaciso.

Ngokwezonyango, inqanaba le-troponin lithathwa njengeliphezulu ukuba lingaphezulu kwe-99% yoko kulindelekileyo kumntu omdala osempilweni (nangona oku kunokwahluka kancinci ngokuxhomekeke ekuchanekeni kovavanyo). Ukuba iziphumo zakho zingaphezulu komda we-99%, oko kubonisa ukuba kukho umonakalo kwimisipha yentliziyo. Ugqirha unokufumanisa ukuba unesifo sentliziyo ngokujonga iimpawu zakho, ezinye iziphumo zovavanyo, kunye nembali yakho yezonyango.

Ezinye iimeko apho i-troponin inokuphakama ziquka:

• Utyando lwentliziyo.
• Iintsholongwane okanye izifo ezibangelwa kukudumba kwentliziyo.
• I-Cardioversion (oku kuquka ukwenza i-electric shock ukuze kulungelelaniswe ukubetha kwentliziyo okungaqhelekanga).

Ndifanele ndimtsalele umnxeba nini ugqirha?

Ekubeni olu vavanyo ludla ngokwenziwa esibhedlele, usenokungabi nanto yokuthetha nogqirha wakho ngalo. Nangona kunjalo, ungabacela ukuba babelane ngeenkcukacha kunye neziphumo zovavanyo lwakho lwe-troponin noogqirha oqhele ukubabona. Oku kubaluleke ngakumbi ukuba uhamba okanye ufumana unyango kwindawo apho iinkcukacha zakho zingagcinwanga khona rhoqo.

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Uvavanyo lwe-troponin sisixhobo esibaluleke kakhulu ekuxilongeni uhlaselo lwentliziyo. Nangona olu vavanyo lukho kangangeminyaka, luye lwaphucuka kakhulu ngeteknoloji ekhoyo namhlanje. Oku kuthetha ukuba iziphumo zingafunyanwa ngokuchanekileyo nangokukhawuleza kunangaphambili. Ngenxa yazo zonke ezi phuculo, olu vavanyo luluncedo olukhulu ekukunikeni unyango olufanelekileyo kwimeko efana nohlaselo lwentliziyo.

Ngoko ke, ukuba wena okanye umntu omaziyo kufuneka enziwe olu vavanyo, ungoyiki ukuluvavanya. Olu vavanyo lunokuba luvavanyo olusindisa ubomi olunika ulwazi oluxabisekileyo malunga nempilo yentliziyo yakho. Ukuba ufumana iimpawu ezifana neentlungu zesifuba okanye ukuphefumla kancinci, musa ukulibazisa kwaye funa ingcebiso kagqirha ngoko nangoko.

Uvavanyo lweTroponin , uhlaselo lwentliziyo, isifo sentliziyo, uvavanyo lwegazi, izihlunu zentliziyo, iTroponin I, iTroponin T