Ngaba wakha wazibuza ukuba isibeleko, iityhubhu ze-fallopian, kunye nomlomo wesibeleko, amalungu akhethekileyo kubafazi, akhula njani ngexesha lokuqala kobomi bomntwana? Yinkqubo emangalisayo neyinkimbinkimbi ngokwenene. Konke kuqala ngeetyhubhu ezimbini ezincinci nezithambileyo ezenzeka ngexesha lesigaba sokukhulelwa. Kwizonyango, ezi sizibiza ngokuba yi-'Müllerian ducts'. Usenokuba awuzange ulive eli gama ngaphambili. Kodwa xa kufikwa kwimpilo yokuzala yomfazi, kubalulekile ukwazi ngale nkqubo yeetyhubhu. Ke namhlanje, masithethe ngayo ngokulula nangendlela onokuyiqonda.
Ngamafutshane, zithini ezi Müllerian Ducts?
Ii-Müllerian ducts ziityhubhu ezimbini ezidibeneyo ezikhula kwimveku njengoko ikhula ngaphakathi kwesibeleko sikanina. Ezi ducts zikwabizwa ngokuba zii-paramesonephric ducts. Nangona kunjalo, igama elithi Müllerian ducts lisetyenziswa kakhulu.
Umsebenzi wazo ophambili kukudala amalungu aphambili enkqubo yokuzala yebhinqa. Ngokukodwa, ezi tyhubhu zimbini zezona zikhula kamva zibe ngala malungu:
- Isibeleko: Lilungu elimangalisayo elithwala kwaye limondla umntwana kangangeenyanga ezilithoba.
- Iityhubhu zeFallopian: Iityhubhu ezimbini ezithwala iqanda ukusuka kwii-ovari ukuya kwisibeleko.
- I-Cervix: Inxalenye esezantsi yesibeleko edibanisa nelungu lobufazi.
- Icandelo elingaphezulu lelungu lobufazi.
Khawucinge nje, ezi tyhubhu zimbini zincinci zezona zikhula zibe ngamalungu abalulekileyo afunekayo ukuze ube ngumama kwaye uzale umntwana kwixesha elizayo.
Into emangalisayo kukuba la ma-Müllerian ducts akhona kuzo zonke iimbumba, nokuba zeziphi na isini, ngexesha lokukhula. Ngoko ke kwenzeka njani ukuba umntwana oyinkwenkwe angaphuhlisi isibeleko, kodwa abe ngumntwana oyintombazana kuphela?
Isizathu soku kukwahlukana ngokwesini, inkqubo apho amalungu esini akhula khona. Kwisibeleko sendoda, kukhutshwa ihomoni ekhethekileyo ebizwa ngokuba yi -anti-Müllerian hormone (AMH) . Le homoni iyayimisa inkqubela ye-Müllerian ducts kwaye iyawanciphisa kancinci kancinci. Ngenxa yoko, isibeleko sendoda asiphuhlisi amalungu anjengesibeleko.
Nangona kunjalo, kwimveku ekhulelweyo, le hormone ye-AMH ayikho. Ngenxa yoko, imibhobho ye-Müllerian ikhula ngaphandle kwengxaki, kwaye amalungu okuzala ebhinqa akhankanyiweyo ngaphambili ayakhiwa.
Ngoko ke zithini iiWolffian Ducts? Yintoni umahluko phakathi kwezi zimbini?
Kunye nemijelo yeMüllerian, enye inkqubo yemijelo ekhoyo kuyo yonke imveku yokuqala yimijelo yeWolffian. Ezi zikwabizwa ngokuba yimijelo ye-mesonephric. Imisebenzi yale mijelo mibini yahlukile ngokupheleleyo kwenye. Ukuze ukuqonde kakuhle oku, jonga itheyibhile engasezantsi.
| Uphawu | Imijelo yeMüllerian | Iipayipi zeWolfian |
|---|---|---|
| Umsebenzi ophambili | Uphuhliso oluya kumalungu omzimba wenkqubo yokuzala yabasetyhini. | Uphuhliso oluya kumalungu omzimba wenkqubo yokuzala yamadoda. |
| Kwisibeleko somfazi | Ikhula kakuhle kwaye yenza isibeleko, iityhubhu ze-fallopian, njl. | Ibola kancinci kancinci, ishiya amaqhekeza angenamsebenzi. |
| Kwisibeleko sendoda | I-Anti-Müllerian Hormone (AMH) ibangela ukuba ukukhula kume kwaye kuphele. | Ikhula kakuhle phantsi kwempembelelo yehomoni ye-testosterone. |
| Amalungu omzimba aphuhlayo nawakhayo | Isibeleko, iityhubhu ze-fallopian, umlomo wesibeleko, inxalenye engentla yesini. | IiVas deferens, i-epididymis, ii-seminal vesicles. |
Ngamafutshane, nangona zombini ezi nkqubo zemithambo yegazi zikhona kwi-embryo enye, phantsi kwempembelelo yeehomoni, enye iyakhula ngelixa enye i-atrophies. Olu lulungelelwano oluhle lwendalo.
Ziphuhliswa njani ezi tyhubhu kwaye zibekwe phi?
Le nkqubo iqala kwasekuqaleni kakhulu xa ukhulelwe. Umntwana ukhulelwa esibelekweni emva kweeveki ezi-3-4 emva kokuzalwa.Eli bali liqala malunga nexesha lokukhulelwa. Ngelo xesha, la ma-Müllerian ducts aqala ukwakheka kwizintso zokuqala (izintso ze-mesonephric) ze-embryo. Ezi zintso zokuqala zezexeshana, kwaye izintso ezisisigxina zikhula kamva.
Ezi ducts zikhula ziyehla njengoko iiprojektha ezinde ezifana nezeminwe zibonakala. Phakathi kweeveki ezisi-8 nezili-12 zokukhulelwa, iincam zeeducts ezimbini zeMüllerian ezihlayo ziyadibana. Olu kudibana kwakha isiseko sezitho ezifana nesibeleko kunye nelungu lobufazi. Ezi ducts zenziwe ziintlobo ezimbini ezikhethekileyo zeeseli.
- Iiseli ze-Epithelial: Ezi zifana nesigqubuthelo sokukhusela amalungu ethu kwaye zikwanceda ekufunxeni nasekukhupheni izinto ezibalulekileyo.
- Iiseli zeMesenchymal: Ezi luhlobo lweeseli ezisisiseko. Oku kuthetha ukuba ezi seli zinokukhula zibe ziintlobo ezahlukeneyo zeeseli njengoko kufuneka.
Ngaba iingxaki ze-Müllerian duct zinokwenzeka?
Ewe, ngamanye amaxesha la ma-Müllerian ducts awaphuhli kakuhle okanye awadibani, nto leyo ebangela iziphene ezahlukeneyo kunye nokungahambi kakuhle. Ezi zidla ngokuba ziimeko zokuzalwa .
Into ebalulekileyo kukuba usenokungazi ukuba unale meko de ube ngumntu omdala okanye utshatile kwaye ulindele umntwana. Kuba kusenokungabikho zimpawu zangaphandle. Abanye abafazi bafumanisa ukuba banale meko kuphela xa bekhangela izizathu zokungazali.
Itheyibhile engezantsi idwelisa ezinye zezona ziphene zixhaphakileyo zeMüllerian duct.
| Igama le-anomaly | Kwenzeka ntoni nje? |
|---|---|
| I-Müllerian agenesis okanye i-hypoplasia | Isibeleko sisenokuba asikho ukususela ekuzalweni (agenesis) okanye sincinci kakhulu kwaye asikhulanga kakuhle (hypoplasia) . Umzekelo oqhelekileyo woku yimeko yemfuza yesifo seMayer-Rokitansky-Kuster-Hauser (MRKH) . |
| I-Vaginal septum (i-membrane kwi-vaginal) | Ukuba le mibhobho mibini ayidibani kakuhle xa idibana ezantsi, kuvela inwebu ejikeleze i-vagina. Oku kunokubangela ukuba i-vagina ivaleke kancinci okanye ngokupheleleyo, okanye kuvele ii-vagina ezimbini. |
| I-Persistent Müllerian duct syndrome (PMDS) | Esi sisifo esingaqhelekanga semfuza esichaphazela amakhwenkwe. Ngenxa yokuba i-AMH hormone ayisebenzi kakuhle, isibeleko kunye nemibhobho ye-fallopian ziyakhula kunye namalungu aqhelekileyo okuzala kwamadoda. La madoda anokuba neengxaki ezifana namasende angaphakamanga. |
| Ukungahambi kakuhle kwesibeleko | Iingxaki zophuhliso lwetyhubhu zinokubangela ukuba isibeleko sitshintshe imo. Imizekelo ibandakanya isibeleko esineembombo ezimbini, isibeleko esineembombo ezimbini, isibeleko esineembombo ezimbini, kunye nesibeleko esinomfanekiso ka-T. |
Abanye abantu abanezi ziphene banokuba neengxaki kwizintso zabo. Oku kungenxa yokuba la malungu mabini akhula ngokusondeleyo ngexesha lokukhulelwa, kwaye isiphene kwelinye sinokuchaphazela elinye.
Ngaba ezi ntlobo zeempazamo ziqhelekile?
Hayi. Akufuneki ukhathazeke ngale nto. Ezi ziimeko ezingaqhelekanga kakhulu. Ngokwezibalo, olu hlobo lwesiphene lwenzeka kwipesenti encinci kakhulu yokuzalwa okuphilayo, phakathi kwe -0.1% kunye ne-3.0% . Oku kuthetha ukuba amathuba okuba into efana nale yenzeke aphantsi kakhulu.
Yeyiphi imibuzo omele uyibuze ugqirha?
Ukuba ugqirha ufumanisa ukuba wena okanye umntwana wakho une-Müllerian duct defect, kuyinto eqhelekileyo ukuba nemibuzo emininzi engqondweni yakho. Ngelo xesha, ngaphandle kokuzibamba, buza ugqirha wakho le mibuzo.
- Ngaba le meko iya kuyichaphazela inzala yam (amandla am okuba nabantwana)?
- Ngaba oku kuya kuzichaphazela iihomoni zam?
- Ziziphi iindlela zonyango zoku? Ngaba utyando luyimfuneko?
- Ngaba ukufikisa kwam kunye nokuya exesheni kwam kuya kwenzeka ngesiqhelo?
Ugqirha wakho uza kunika iimpendulo ezicacileyo kuyo yonke le mibuzo aze akunike ulwalathiso olufunayo.
Ngaba ezi ntlobo zeempazamo zingathintelwa ngexesha lokukhulelwa?
Le yingxaki abantu abaninzi abanayo. Inyaniso kukuba, akukho ndlela yokuthintela ngokupheleleyo iziphene zendlela yokuhambisa amanzi emzimbeni (Müllerian duct defects).Kuba ezi zinto zihlala zibangelwa zizizathu zemfuza okanye impazamo eyenzeka ngokungacwangciswanga ngexesha lokukhula komntwana ongekazalwa.
Kodwa, oko akuthethi ukuba akukho nto sinokuyenza. Njengomama okhulelweyo, ungalandela indlela yokuphila enempilo ukunciphisa umngcipheko wakho wokuzalwa uneziphene ngokubanzi. Oku kubalulekile kungekuphela nje kwezi ntlobo zeziphene, kodwa nakwimpilo iyonke yomntwana wakho.
- Ziphephe ngokupheleleyo iziyobisi ezingekho mthethweni kunye nentsangu.
- Kuphephe ukutshaya notywala ngokupheleleyo. Ezi zinto ziyingozi kakhulu kumntwana ongekazalwa.
- Qiniseka ukuba ufumana iingcebiso zonyango ezifanelekileyo kunye nonyango lokukhulelwa ngexesha lokukhulelwa.
- Ukuba unezifo ezingapheliyo ezifana nesifo seswekile okanye uxinzelelo lwegazi oluphezulu, zilawule kakuhle ngaphambi kokuba ukhulelwe.
- Sela iivithamini zokukhulelwa ezine- folic acid kanye njengoko ugqirha wakho ekucebisile.
- Gcina ubunzima bakho busempilweni.
- Yitya ukutya okunesondlo kwaye wenze umthambo yonke imihla.
Ngezi zinto zilula, ungadala indawo efanelekileyo yokukhula kakuhle komntwana wakho ongekazalwa.
Umyalezo Wokuya Ekhaya
- Ii-Müllerian ducts yinkqubo yee-ducts ezakha ngexesha lokukhula komntwana kwaye zibalulekile ekuphuhlisweni kwamalungu okuzala ebhinqa, njengesibeleko kunye neetyhubhu ze-fallopian.
- Ezi ziphene zophuhliso zikhona ekuzalweni kwaye zisenokungabonwa de kube mdala okanye xa kulindeleke ukuba abantwana babe ngabantwana.
- Ezi ziphene azixhaphakanga kakhulu, kwaye uninzi lwazo luneendlela zonyango kunye neendlela zokulawula.
- Ukuba uneengxaki okanye amathandabuzo malunga noku, kubaluleke kakhulu ukuthetha ngokukhululekileyo nogqirha wakho ngayo kwaye ufumane ingcebiso efanelekileyo.
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