Xa uninzi lwethu lusiva igama elithi isifo seswekile, silicinga njengesifo esichaphazela amanqanaba eswekile emzimbeni, intliziyo, izintso kunye namehlo. Yiyo loo nto. Kodwa ubusazi, uphando lwakutshanje lufumanise ukuba isifo seswekile sinokuchaphazela ngqo ingqondo kunye nenkumbulo yethu. Abanye oogqirha basebenzisa negama elitsha lale meko, eliyi-'Type 3 Diabetes'. Ke namhlanje, masithethe ngale nto.
Yintoni kanye kanye isifo seswekile 'sohlobo lwesithathu'?
Ngamafutshane, igama elithi 'isifo seswekile sohlobo lwesithathu' ligama elicetywe ziingcali ezithile kwisifo sika-Alzheimer. Isizathu kukuba zikholelwa ukuba unobangela oyintloko wezinye iintlobo zesifo sika-Alzheimer kukulimala okunokwenziwa sisifo seswekile engqondweni ngokuhamba kwexesha.
Kangangexesha elide, izazinzulu bezicinga ukuba i-hormone ye-insulin ayinanto yakwenza nokusebenza kwengqondo. Kodwa ngoku siyazi ukuba akunjalo. I-insulin ikwahamba iye kwiiseli zethu zengqondo. Kwaye le insulin ibaluleke kakhulu ekucingeni nasekukhumbuleni kwethu.
Ngoko ke, xa ingqondo yakho ingafumani i-insulin eyaneleyo, okanye xa ingakwazi ukuyisebenzisa i-insulin, iyifumana ngokufanelekileyo (siyibiza ngokuba yi-insulin resistance), ukusebenza kwemihla ngemihla kweeseli zengqondo kuqala ukuwohloka. Oku kwenzeka kwisifo sika-Alzheimer.
Kodwa kukho into enye ebalulekileyo ekufuneka uyikhumbule. 'Isifo seswekile sohlobo lwesithathu' asikabi sisifo esamkelekileyo kwezonyango. Sisekwinqanaba lophando. Ngenxa yoko, akukho gqirha uza kukuxelela ngokusesikweni ukuba unesifo seswekile sohlobo lwesithathu.
Kutheni oku kusenzeka? Zithini izizathu?
Uphando lubonise ngokucacileyo ukuba abantu abanesifo seswekile sangaphambi kwexesha okanye isifo seswekile sohlobo lwesibini basengozini enkulu yokufumana isifo se-Alzheimer kunye nezinye izifo zengqondo kamva ebomini. Oku kungenxa yezizathu ezahlukeneyo.
1. Ukonakala kunye nokudumba kwemithambo yegazi
Isifo seswekile sinyusa umngcipheko wesifo sentliziyo kunye nesifo sohlangothi. Kwakhona, xa amanqanaba eswekile egazini enyuka, ukudumba kwenzeka emzimbeni. Oku akulunganga kwimithambo yegazi yethu. Xa imithambo yegazi ebuthathaka engqondweni yonakele ngale ndlela, inokubangela isifo se-Alzheimer.
2. Ukuphazamiseka konxibelelwano phakathi kweeseli zemithambo-luvo
Xa amanqanaba eswekile egazini enyuka, ii-protein clumps ezibizwa ngokuba yi-beta-amyloid ziyaqokelelana engqondweni. Ezi -clumps ziyahlangana kwaye zibambeke phakathi kwee-nerve cells engqondweni. Njenge-traffic jams endleleni, ezi protein clumps zithintela ii-nerve cells ukuba zinxibelelane. Olu luphawu oluphambili lwesifo sika-Alzheimer.
3. Ukuxinana kweproteni yeTau
Khawuthelekelele ukuba ingqondo yethu inenkqubo yeetyhubhu ezincinci (ii-microtubules) ezithutha izondlo zibuyela umva ngaphakathi kwiiseli zemithambo-luvo. Iproteni ebizwa ngokuba yi-tau isebenza 'njengomlindi' ukugcina le nkqubo yeetyhubhu ihlelekile kwaye ingaphambuki. Engqondweni yomntu onesifo sika-Alzheimer, le protein ye-tau iyabhideka. Emva koko inkqubo yeetyhubhu iyavalwa, iiseli azikwazi ukuthutha oko zikudingayo, kwaye iiseli ziyafa. Ezinye izifundo zifumanise ukuba kukho ezinye zeeproteni ze-tau ezibhidekileyo kwiingqondo zabantu abanesifo seswekile.
4. Ukumelana ne-insulin
Le yeyona nto iphambili kwingcamango 'yesifo seswekile sohlobo lwesithathu'. Njengeeseli emzimbeni, xa iiseli zengqondo zingaphenduli kakuhle kwi-insulin, ezo seli azifumani amandla (amafutha) eziwadingayo. Emva koko ukusebenza kwengqondo kuyaphazamiseka. Kwakhona, ukumelana ne-insulin engqondweni kwandisa imeko enobungozi ebizwa ngokuba yi-oxidative stress.
| Ezinye izinto ezonyusa umngcipheko | |
|---|---|
| Izinto ezibangela i-genetic | Ngaphezulu kwesiqingatha sezigulane ze-Alzheimer's zine-gene ebizwa ngokuba yi-APOE4. Le gene ifunyenwe isenza kube nzima kwingqondo ukusebenzisa i-insulin. |
| Indlela yokuphila | - Uxinzelelo olungapheliyo - Ukungazilolongi - Ukutya okuneekhalori ezininzi, iswekile namafutha, kunye nefayibha ephantsi |
Zingaba yintoni iimpawu zale meko?
Iimpawu ezinxulumene nengcamango 'yesifo seswekile sohlobo lwesithathu' ziyafana nezo zesifo sika-Alzheimer. Ezi zinokubonakala kwizigaba zokuqala.
| Udidi lweempawu | Imizekelo |
|---|---|
| Iingxaki ngenkumbulo nokucinga | - Ukulibala iintsuku okanye iziganeko ezibalulekileyo. - Ukubuza umbuzo ofanayo ngokuphindaphindiweyo. - Ubunzima bokulandela into enamanyathelo aliqela, njengeresiphi. - Ukulibala into obufuna ukuyithetha ngelixa uthetha. |
| Utshintsho kwimisebenzi yemihla ngemihla | - Ukulibala indlela yokusebenzisa isixhobo ebesisetyenziswa ixesha elide (umz. i-remote yeTV). - Ukushiya izinto zakho kwiindawo ezingaziwayo. - Ukulahlekelwa ngumdla kucoceko. - Ukwenza izigqibo ezingalunganga malunga nemali. |
| Utshintsho kwindlela yokuziphatha kunye neemvakalelo | - Kancinci kancinci uzihlukanise nabahlobo kunye nosapho. - Ukungafuni ukuphuma kwindawo 'yokuzithuthuzela'. - Ukuba nomsindo okanye ukuxhalaba lula. |
Ukuba wena okanye umntu omthandayo unezinye zezi mpawu, ingakumbi ukuba nawe unesifo seswekile, nceda uthethe nogqirha wakho ngazo. Ungazityesheli.
Masifunde ngokuxilongwa kunye nonyango.
Njengoko besitshilo ngaphambili, akukho kuxilongwa ngokusesikweni kwesifo seswekile sohlobo lwesithathu, ngoko ke ugqirha akanakwenza uvavanyo lokuqinisekisa oko. Nangona kunjalo, ukuba uneengxaki ngenkumbulo yakho, ugqirha wakho uza kukuvavanya ukuba awunaso isifo sengqondo esixhalabisayo.
Oku kungabandakanya imibuzo yesimo sengqondo, iiskeni zobuchopho (ii-MRI okanye ii-CT scans), kwaye ngamanye amaxesha uvavanyo lolwelo lomqolo.
Xa kufikwa kunyango, akukho nyango luthile lwe-'Type 3 Diabetes'. Kodwa kukho izinto ezimbini ezibaluleke kakhulu onokuzenza:
1. Ukuba unesifo seswekile, silawule kakuhle. Kubalulekile ukusebenzisa amayeza owanikwe ngugqirha wakho ngokuchanekileyo kwaye ulawule amanqanaba eswekile egazini lakho.
2. Fumana unyango lwangoku lwesifo sika-Alzheimer. Nangona olu nyango lungenakusinyanga ngokupheleleyo esi sifo, lunokunceda ekunciphiseni izinga apho iimpawu ziba mandundu khona.
Olunye uphando lukwacebise ukuba amanye amayeza esifo seswekile, anjenge-metformin kunye ne-pioglitazone, anokunciphisa umngcipheko wokuba ne-dementia kamva ebomini. Uphando olongezelelweyo luyaqhubeka.
Ungayikhusela njani impilo yengqondo yakho kwaye unciphise le ngozi?
Ukuze sihlale sikhuselekile kule ngozi, kukho izinto ezibalulekileyo esinokuzongeza kwindlela esiphila ngayo. Ezi zilungile kakhulu kwimpilo yengqondo yakho, kunye nomzimba wakho wonke.
- Hlala usempilweni: Zilolonge imizuzu engama-30 ngosuku, ubuncinane iintsuku ezi-5 ngeveki. Khetha into oyithandayo. Ingaba yinto nayiphi na, njengokuhamba, ukudanisa, okanye ukukhwela ibhayisekile.
- Kuphephe ukutshaya: Ukuba uyatshaya, cela uncedo kugqirha wakho ukuze uyeke.
- Gcina ubunzima obusempilweni: Yitya iziqhamo, imifuno, ukutya okuziinkozo (njengerayisi emdaka), inyama engenamafutha amaninzi, kunye neemveliso zobisi ezinamafutha aphantsi. Nciphisa iswekile kunye namafutha agcweleyo.
- Lumka noxinzelelo lwakho lwegazi: Ukuba ugqirha wakho ubhale amayeza, thatha kanye njengoko eyalelwe.
- Lala kakuhle: Zama ukulala kakuhle iiyure ezisi-7-8 yonke imihla.
- Yiba nobudlelwane nabantu: Chitha ixesha nabahlobo kunye nosapho. Ukuba wedwa kunye nokwahlukaniswa nabantu akulunganga engqondweni.
- Funda izinto ezintsha: Izinto ezinje ngokufunda ulwimi olutsha, isixhobo somculo, okanye ukusombulula iiphazili zakha unxibelelwano olutsha phakathi kweeseli zobuchopho.
Umyalezo Wokuya Ekhaya
- Igama elithi 'isifo seswekile sohlobo lwesithathu' lisetyenziswa ukuchaza umonakalo wengqondo obangelwa sisifo seswekile onokukhokelela kwisifo se-Alzheimer. Nangona kunjalo, oku akukabikho sizathu sokuba umntu afumane isifo esisemthethweni.
- Amanqanaba aphezulu eswekile egazini kunye nokunganyamezelani ne-insulin kungonakalisa kakhulu iiseli zobuchopho bakho kwaye kuphazamise inkumbulo.
- Ukuba unesifo seswekile, ukugcina amanqanaba eswekile egazini lakho elawulwa kakuhle kubaluleke kakhulu kwimpilo yomzimba wakho kunye nengqondo yakho.
- Ukuba ubona naluphi na ulahleko okanye utshintsho kwinkumbulo yakho, ingakumbi ukuba unesifo seswekile, musa ukulibala kwaye uthethe nogqirha wakho ngoko nangoko.
- Ngokulandela indlela yokuphila enempilo (ukutya okunempilo, ukuzilolonga, ukunxibelelana nabantu) unokukhusela umzimba wakho kunye nengqondo yakho.
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