Ngaba inkqubo yokuzikhusela yomzimba wakho iyadlala ngawe? Masifunde nge-Autoimmune Pancreatitis ngendlela elula!

Sinenkqubo yokuzikhusela emangalisayo emizimbeni yethu, akunjalo? Yiloo nto siyibiza ngokuba yinkqubo yokuzikhusela. Isikhusela ngokulwa neentsholongwane, iibhaktheriya, kunye neentsholongwane ezibangela izifo. Kodwa khawucinge, kuthekani ukuba ngamanye amaxesha le nkqubo yethu yokuzikhusela idideka neeseli ezilungileyo emizimbeni yethu ize iqale ukuzihlasela? Kulapho ke kwenzeka khona oku, okubizwa ngokuba yi-"Autoimmune Pancreatitis". Ngamafutshane, inkqubo yakho yokuzikhusela iqala ukusebenza nxamnye nepancreas yakho.

Yintoni "i-Autoimmune Pancreatitis"? Ngamafutshane...

Cinga ngenkqubo yomzimba wakho yokuzikhusela njengomkhosi okhusela ilizwe. Umsebenzi walo mkhosi kukukhusela ilizwe kwiintshaba zangaphandle (ezifana neentsholongwane kunye neentsholongwane). Kodwa kwi-`(Autoimmune Pancreatitis)`, lo mkhosi wenza impazamo kwaye uhlasele abemi abamsulwa belizwe lawo (oko kukuthi, iiseli ezisempilweni kwi-pancreas) becinga ukuba ziintshaba. Ngenxa yoko, i-pancreas iyavuvukala, yenzakale, kwaye umsebenzi wayo uyaphazamiseka. Oku sikubiza ngokuba yi-autoimmune pancreatitis .

Ixhaphake kangakanani le sifo?

Enyanisweni, `(Autoimmune Pancreatitis)` sisifo esingaqhelekanga . Sidla ngokuvela kumntu omnye kubantu abayi-1000. Ukuba sithatha iimeko zokudumba zepancreas ezihlala ixesha elide (`chronic pancreatitis`), zimalunga ne-2% kuphela eziwela kolu didi `(Autoimmune Pancreatitis)`. Ngoko ke, esi asisosifo esichaphazela wonke umntu.

Ngaba kukho iintlobo ze-`(Autoimmune Pancreatitis)`?

Ewe, kukho iintlobo ezimbini ze-`(Autoimmune Pancreatitis)`. Masibone ukuba zeziphi.

1. Uhlobo 1 lwe-Autoimmune Pancreatitis

Olu lolona hlobo luqhelekileyo . Kule, sineproteni eninzi ebizwa ngokuba yi-`(Immunoglobulin G4)` okanye `(IgG4)` emzimbeni wethu. Le `(IgG4)` luhlobo lwe-antibody. Xa kukho ukudumba okanye ukudumba naphi na emzimbeni, inqanaba lale `(IgG4)` liyakhula.

Kodwa kolu hlobo lokuqala, ingxaki ayipheleli nje kwi-pancreas. Ingachaphazela nezinye izitho zomzimba wethu. Umzekelo:

• Imibhobho yenyongo: Le yimibhobho efana neetyhubhu ezithwala inyongo ukusuka esibindini ukuya emathunjini amancinci.
• Iityhubhu zezintso: Iityhubhu ezikwizintso.
• Isibindi
• Imiphunga
• Inyongo
• Iindlala zamathe
• Indlala yegilo

Ukudumba kunye nomonakalo kunokwenzeka nakwiindawo ezinje.

2. Uhlobo lwesibini lwe-Autoimmune Pancreatitis

Olu hlobo luchaphazela kuphela ipancreas . Okwenzekayo apha kukuba uhlobo lweseli emhlophe yegazi ebizwa ngokuba yi-"neutrophils" yonakalisa ipancreas kunye nemijelo yepancreas. Le meko idla ngokubonakala kubantu abancinci.Kwakhona banokuba nesifo samathumbu esibangela ukuvuvukala (IBD).

Zithini izizathu ze-`(Autoimmune Pancreatitis)`? Ngaba kukho naziphi na izinto ezibangela umngcipheko?

Abaphandi basazama ukufumana unobangela ochanekileyo , kodwa ngokuqhelekileyo kwenzeka kubantu abaphakathi kweminyaka engama-50 nama-60 ubudala. Nangona kunjalo, inokwenzeka kwangethuba. Amadoda anamathuba aphindwe kabini okufumana esi sifo kunabafazi.

Ngamanye amaxesha, kucingelwa ukuba yindlela umzimba osabela ngayo kwisifo sebhaktheriya. Ukongeza, abantu abanezinye izifo zokuzikhusela komzimba basengozini enkulu yokuhlaselwa sisifo. Umzekelo:

• (Hashimoto's thyroiditis): Oku kubangela ukuba i-thyroid gland ingasebenzi kakuhle (hypothyroidism).
• (Isifo samathumbu esidumbileyo - IBD): Ingakumbi iimeko ezifana ne-`(ulcerative colitis)`.
• (I-cholangitis yenyongo yokuqala)
• I-Retroperitoneal fibrosis: Ukwakheka kwezicubu ezifana nezibazi kulwelo olungasemva kwesisu.
• I-rheumatoid arthritis: Ukudumba kwamalungu.
• (I-Sarcoidosis)
• (Isifo sikaSjögren)

Ukuba unezinye iimeko zokuzikhusela komzimba ezifana nale, kungcono ukuba ukhathazeke kancinci nge-Autoimmune Pancreatitis.

Zithini iimpawu ze-`(Autoimmune Pancreatitis)`?

Kwinqanaba lokuqala lesi sifo , kusenokungabikho zimpawu . Nangona kunjalo, njengoko isifo siqhubeka, imibhobho yepancreas iqala ukucutheka, nto leyo ethintela ii-enzymes ezikhutshwa yipancreas ukuba zingakwazi ukudlula ngokufanelekileyo.

Ukuvaleka kwendlela yokugaya i-pancreatic kunokubangela iimpawu ezifana nezi:

• Intlungu yesisu esingaphezulu
• Intlungu ephakathi komqolo
• Urhudo
• Isicaphucaphu/ukuhlanza
• Ukuhla ukusinda

Kubalulekile: Ezinye zezi mpawu zinokubonakala nakumhlaza wepancreatic. Ke ngoko, ukuba unazo ezi mpawu, kulungile ukuba ungoyiki kwaye ubone ugqirha ngokukhawuleza ukuze ufumane ukuba yintoni kanye kanye ingxaki . Ukuba ne-`(Autoimmune Pancreatitis)` akuthethi ukuba unomhlaza.

Ukongeza, i-autoimmune pancreatitis inokubangela ukudumba, ukukhula okungenamhlaza, kunye nee-cysts ezizaliswe lulwelo kwi-pancreas. Ukuba oku kudumba, amaqhuma, okanye ii-cysts zenzeka entlokweni ye-pancreas yakho, zinokuvala i-bile duct, enokuthintela i-bile ukuba ingangeni kakuhle emathunjini amancinci. I-Bile ine-pigment ebizwa ngokuba yi-bilirubin. Xa le bilirubin iqokelelana egazini, inokubangela i-jaundice.Ulusu kunye namhlophe emehlweni aba tyheli (i-jaundice), kwaye ungaziva udiniwe. Xa i-bilirubin isanda kumchamo , umchamo uba mnyama . Xa i-bilirubin ikhutshwa emathunjini , indle inokuba nombala okhanyayo .

Ziziphi iingxaki ezinokubakho ze-`(Autoimmune Pancreatitis)`?

Ukudumba okungapheliyo kwepancreas kunokubangela isicaphucaphu, ukwehla kobunzima, kunye nentlungu engapheliyo esiswini esingaphezulu nasemqolo. Kwakhona, ukuba iiseli ezivelisa i-insulin kwipancreas zonakele , isifo seswekile sinokuvela.

Ii-antibodies ze-IgG4 azinakuhlasela i-pancreas kuphela, kodwa nezinye izitho zomzimba, ingakumbi kwi-Type 1. Ezi zitho ziquka:

• Imibhobho yenyongo
• Iindlala zamathe
• Iindlala zeLacrimal
• Indlala yegilo (`Igilo`)
• Izintso
• Intliziyo
• Imiphunga kunye nepleura (ulwelo lwemiphunga)

Ifunyanwa njani i-Autoimmune Pancreatitis?

Ukuze uxilonge esi sifo ngokuchanekileyo kwaye uqiniseke ukuba asingomhlaza wepancreatic, kuya kufuneka uvavanyo oluninzi. Kuya kufuneka wenze uvavanyo olufana nolu:

• Uvavanyo lwegazi: Olu vavanyo lujonga amanqanaba aphezulu ngokungaqhelekanga e-IgG4, kunye nokusebenza kwesibindi kunye namanqanaba eentlobo ezithile zeeseli zegazi.
• Uvavanyo lokufota: Olu lujonga ubungakanani bepancreas, nokuba kukho amanxeba na, okanye ukuba imibhobho inciphile na. Imizekelo yezi vavanyo yi `(CT scan)` kunye `(MRI scan)`.
• I-Biopsy: Oku kuquka ukuthatha iqhekeza elincinci lesicwili kwi-pancreas yakho uze ulihlolisise phantsi kwe-microscope. Oku kudla ngokwenziwa ngenkqubo ye-endoscopic encinci ebizwa ngokuba yi-Endoscopic Ultrasound (EUS). Kule nkqubo, ugqirha wakho ufaka ityhubhu ende, eguquguqukayo (enesixhobo esikhanyayo nesine-ultrasound kwelinye icala) esiswini sakho nasemathunjini ukuze ajonge i-pancreas yakho. Emva koko kuthathwa isampuli ye-biopsy ngesisu sakho okanye emathunjini. Ngamanye amaxesha, ugqirha wotyando unokufuna ukwenza ukusika okuncinci eluswini lwakho (laparoscopy) ukuze athathe isampuli ye-biopsy.
• Uvavanyo lwe-corticosteroid: Oku kunceda ukuqinisekisa ukuxilongwa. Unikwa ii-steroids ixesha elifutshane ukuze ubone ukuba amanqanaba akho e-IgG4 ayancipha na kwaye iimvavanyo zakho zomfanekiso ziyaphucuka.

Inyangwa njani i-`(Autoimmune Pancreatitis)`?

Okumangalisayo kukuba, kubantu abambalwa kakhulu, esi sifo siphela ngokwaso ngaphandle konyango . Kodwa kwabaninzi, unyango luyadingeka .

I-Autoimmune Pancreatitis inyangwa kakhulu nge-corticosteroids.Uhlobo lwamayeza olubizwa ngokuba yi-steroid. Umzekelo, amayeza afana ne-`(prednisone)` okanye `(prednisolone)`. La mayeza asebenza ngokunciphisa ukudumba kunye nokuthomalalisa inkqubo yomzimba yokuzikhusela esebenza kakhulu. Unyango ludla ngokuqala ngedosi ephezulu yee-steroids. Emva koko idosi iyancipha kancinci kancinci (`inciphile`).

Ukuba awunazo iingxaki, awudingi naluphi na unyango olongezelelweyo. Unyango olufunekayo luxhomekeke kuhlobo lweengxaki. Ukuba kukho ukuncitshiswa komjelo wepancreas (`ukuncitshiswa komjelo`), inkqubo inokwenziwa ukuvula umjelo nokuwuqinisa ngesixhobo esine-hollow mesh (`stent`).

Ndingakuthintela na ukufumana `(Autoimmune Pancreatitis)`?

Enyanisweni, akukho nto unokuyenza ukuthintela esi sifo ukuba singabikho kuba siyinkinga kwinkqubo yethu yokuzikhusela komzimba.

Iyintoni imbono yabantu abane-`(Autoimmune Pancreatitis)`?

Uninzi lwabantu luyaphila kakuhle emva konyango lwe-corticosteroid , kwaye akukho ngxaki. Ukuba ne-autoimmune pancreatitis akuchaphazeli ubomi bakho .

Nangona kunjalo, `(Autoimmune Pancreatitis)` inokuphinda ivele (iphinde ivele) . Oku kuqhelekile ngakumbi kubantu abanohlobo lokuqala (`Uhlobo 1`). Esi sifo sinokuthi siphinde sivele kwiminyaka emithathu yokuqala emva kokufunyaniswa kwaso. Umntu onesifo siphinde sivele usenokuba neengxaki ezininzi.

Kuza kwenzeka ntoni ukuba esi sifo siphinda sibuye?

Ukuba ilawulwa ngempumelelo, nabo banesifo esiphindaphindayo banokuphila ubomi obusempilweni nobusebenzayo .

Kusenokufuneka uqale ukusebenzisa ii-corticosteroids kwakhona. Abanye abantu baqhubeka nonyango lwe-steroid iminyaka eliqela ukuthintela ukuba iimpawu zingabuyi. Oogqirha banokuzama nezinye iziyobisi zonyango olusebenza kakhulu kwinkqubo yomzimba yokuzikhusela (iziyobisi zokugonya kunye nezokuthintela amajoni omzimba).

Ndiza kuziva njani ngexesha lonyango?

Ezinye iziphumo ebezingalindelekanga zinokwenzeka xa usebenzisa ii-steroids. Umzekelo, ukuphazamiseka kwesisu, ukwanda kokutya, ukungazinzi, kunye nobunzima bokulala. Ezi ziphumo bezingalindelekanga zinokuphazamisa ubomi bemihla ngemihla, kodwa zezokwexeshana . Ukuze ufumane okuninzi kunyango lwakho lwe-Autoimmune Pancreatitis, kubalulekile ukuqhubeka nokusebenzisa ii-steroids njengoko ugqirha wakho ekuyalele .

Ukuba iziphumo ebezingalindelekanga zikhathaza kakhulu ukuba unganyamezela, qiniseka ukuba wazise ugqirha wakho ngaphambi kokuba uyeke unyango. Angakunika unyango olongezelelweyo ukukunceda ufumane isiqabu, okanye atshintshe isicwangciso sakho sonyango.

Ndingabuyela nini kwimisebenzi yam yesiqhelo emva konyango lwe-`(Autoimmune Pancreatitis)`?

Unyango lwe-steroid ludla ngokunceda kwiimpawu ze-`(Autoimmune Pancreatitis)` kwiiveki ezimbalwa.Abantu abaninzi babuyela kwimisebenzi yabo yesiqhelo emva kokuba iimpawu zabo ziphelile.

I-Autoimmune Pancreatitis yimeko engaqhelekanga yokuvuvukala enokuchaphazela ukusebenza kwepancreas. Ukubona ugqirha oqhelene nezifo zepancreas kunokukunceda ufumane unyango olufanelekileyo olufunekayo. Uninzi lwabantu luyachacha ngokupheleleyo emva kokuthatha ii-steroids . Abanye abantu banokufuna unyango olongezelelweyo lwe-Autoimmune Pancreatitis ukuze bafumane isiqabu sexesha elide.

Okokugqibela, khumbula oku (Umyalezo Wokuya Ekhaya)

• I-Autoimmune Pancreatitis yimeko engaqhelekanga apho inkqubo yakho yomzimba yokuzikhusela ihlasela i-pancreas yakho.
• Ukuba uneempawu ezifana neentlungu zesisu, ukwehla kobunzima, okanye i-jaundice , qiniseka ukuba ucela iingcebiso zonyango .
• Lo asingomhlaza wepancreatic, kodwa iimpawu ziyafana, ngoko ke ukuxilongwa ngokuchanekileyo kubalulekile .
• Unyango oluphambili yi-corticosteroids.
• Abantu abaninzi bayaphila kakuhle ngonyango, kodwa esi sifo sinokuphinda sibuye.
• Kubaluleke kakhulu ukulandela imiyalelo kagqirha ngqo ukuze uphile ngokukhawuleza .

Khumbula, awuwedwa. Kuqhelekile ukuba neengcinga ezininzi ezidlula engqondweni yakho kwimeko efana nale. Ngoko ke, vula ingqondo nogqirha wakho kwaye ubuze imibuzo yakho. Balapha ukukunceda.

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