Unika igazi ukujonga i-cholesterol yakho uze ufumane ingxelo. I-LDL, i-HDL, ii-triglycerides... Kuyintuthuzelo enkulu ukubona ukuba yonke into iqhelekile, akunjalo? "Owu... andina-cholesterol, andizukuba neengxaki zentliziyo," unokucinga. Kodwa, ubusazi ngotshaba olufihlakeleyo olungabonakaliyo kule ngxelo ye-cholesterol eqhelekileyo, kodwa olunempembelelo enkulu kwisifo sentliziyo? Namhlanje siza kuthetha ngaloo nto.
Yintoni iLipoprotein(a) okanye iLp(a)?
Ngamafutshane, iLipoprotein(a) , okanye iLp(a) ngamafutshane, yintwana enamafutha egazini lethu, njenge-cholesterol. Kodwa le ikhethekile kancinci. Le ntwana ye-Lp(a) inokunamathela eludongeni lwemithambo yegazi yethu (imithambo yegazi) kakhulu kune -LDL cholesterol esiyaziyo sonke njenge "cholesterol embi", ize ivale kancinci kancinci. Khawucinge ngengxinano yezithuthi endleleni, xa le Lp(a) isanda, ukuhamba kwegazi ngaphakathi kwemithambo yegazi yethu kuyathinteleka. Kwizonyango, sibiza esi sifo sentliziyo esine-atherosclerotic (ASCVD) . Le meko yiyo ekhokelela kwizifo ezinzulu ezifana nokuhlaselwa yintliziyo kunye nestroke ngokuhamba kwexesha.
Eyona ngxaki inkulu ngale nto kukuba inqanaba le-Lp(a) liyanda ngaphezu koko sikutyayo okanye esikwenza umthambo, kodwa kungenxa yezakhi zofuzo zethu. Oko kukuthi, yinto esiyizuza njengelifa kubazali bethu. Nokuba uphila ubomi obunjani na, inqanaba lakho le-Lp(a) linokuba phezulu ngokwezakhi zofuzo. Yiyo loo nto, nokuba ingxelo yakho ye-cholesterol eqhelekileyo ilungile, kubalulekile ukuba uqaphele le ngozi ifihlakeleyo.
Kuqikelelwa ukuba umntu omnye kwabahlanu emhlabeni unezinga eliphezulu le-Lp(a) eliyingozi, kodwa abantu abaninzi abazi ngaloo nto.
Kutheni olu vavanyo lubaluleke kangaka? Ngubani osengozini enkulu?
Kude kube kutshanje, uvavanyo lwe-Lp(a) beluxoxwa kakhulu phakathi koogqirha bentliziyo. Kodwa oko kuyatshintsha. Imibutho yezonyango ephambili ehlabathini ngoku icebisa ukuba wonke umntu omdala kufuneka enze uvavanyo lwe-Lp(a) ubuncinane kube kanye ebomini bakhe .
Khawucinge nje, kukho abanye abaguli abaye bahlaselwa yintliziyo kabini okanye kathathu, bahlaselwa yi-stents, batyandwa nge-bypass, kodwa akukho sizathu sifumanekayo sokuba kutheni oku kusenzeka. Kwiimeko ezinjalo, xa inqanaba le-Lp(a) lijongwa, lifunyaniswa liphezulu kakhulu. Oko kuthetha ukuba, esi sisenokuba sisizathu esiphambili esifihliweyo ixesha elide.
Makhe sijonge umahluko phakathi kovavanyo lwe-cholesterol oluqhelekileyo kunye novavanyo lwe-Lp(a) kwitheyibhile engasezantsi.
| Uphawu | Uvavanyo lweCholesterol Jikelele (Iprofayili yeLipid) | Uvavanyo lwe-Lp(a) |
|---|---|---|
| Yintoni evavanywayo? | Ilinganisa izinto ezifana ne-LDL, i-HDL, i-Total Cholesterol, kunye ne-Triglycerides. | Kuphela lisuntswana elithile elibizwa ngokuba yiLipoprotein(a) elilinganiswayo. |
| Izinto ezinefuthe | Ukutya, umthambo, kunye nobunzima bomzimba kunokwenza umahluko omkhulu. | Ixhomekeka kakhulu kwiijini. Indlela yokuphila ayinampembelelo ingako. |
| Kujongwa kangaphi | Ngokucetyiswa ngugqirha, kufuneka uhlolwe rhoqo (umz. kanye ngonyaka). | Ukuhlolwa kube kanye ebomini kudla ngokwanela. |
Ngubani osengozini enkulu?
Nangona nabani na enokuba namanqanaba aphezulu e-Lp(a), amanye amaqela anokuba semngciphekweni omkhulu kancinci:
- Abantu abanembali yesifo sentliziyo kusapho: Ukuba isalamane esisondeleyo, esifana nomama wakho, utata, okanye abantakwenu, siye saba nesifo sentliziyo okanye isifo sohlangothi sisemncinci (ngaphantsi kweminyaka engama-55 kumadoda, ngaphantsi kweminyaka engama-65 kubafazi), kunokwenzeka ukuba ube namanqanaba aphezulu e-Lp(a).
- Amanye amaqela eentlanga: Izifundo zibonise ukuba abantu abazalwa eAfrika banokuba namanqanaba aphezulu e-Lp(a) kunamanye amaqela eentlanga.
- Abafazi abasele begqithile exesheni: Amanqanaba e-Lp(a) anokunyuka kancinci kubafazi emva kokugqithela exesheni.
- Izigulane ezinesifo seswekile: Ukudibana kwesifo seswekile kunye namanqanaba aphezulu e-Lp(a) kuyandisa kakhulu umngcipheko wesifo sentliziyo.
Senza ntoni ukuba inqanaba le-Lp(a) liphezulu?
Kulungile, ngoku mhlawumbi uyazibuza, "Kuthekani ukuba inqanaba lam le-Lp(a) liphezulu? Ngaba likho unyango loku?" Lo ngumbuzo obaluleke kakhulu.
Okwangoku, amayeza ajolise ngqo kwaye anciphise amanqanaba e-Lp(a) asekwinqanaba lokugqibela lophando. Kukho ithemba elikhulu ngamayeza afana nePelacarsen , eziphumo zawo kulindeleke ukuba zifumaneke ngo-2025.
Kodwa, awunakulinda nje ukuba kwenzeke. Eyona nto ibalulekileyo kukwazi ukuba inqanaba lakho le-Lp(a) liphezulu. Ngaleyo ndlela, wena nogqirha wakho ningathatha amanye amanyathelo okunciphisa umngcipheko wesifo sentliziyo sakho siphela.
Ukwazi inqanaba lakho le-Lp(a) kufana nokwazi kwangaphambili malunga nokugoba okuyingozi endleleni. Nokuba awukwazi ukuphepha ukugoba, ungacotha isantya kwaye uqhube ngononophelo.
Ukuba inqanaba lakho le-Lp(a) liphezulu, ugqirha wakho uya kucebisa oku kulandelayo:
1. Lawula ngokungqongqo i-cholesterol ye-LDL: Ukuba i-Lp(a) yakho iphezulu, kubaluleke kakhulu ukugcina amanqanaba e-LDL ("i-cholesterol embi") esezantsi kangangoko. Oku kungenziwa ngokunika amayeza anjengee -statins .
2. Ukulawula ezinye izinto ezinobungozi: Zonke ezinye izinto ezinobungozi ezifana noxinzelelo lwegazi oluphezulu, isifo seswekile, ukutshaya, kunye nokutyeba kakhulu kufuneka zilawulwe kakuhle.
3. Ukwazisa usapho: Ekubeni amanqanaba e-Lp(a) efuzo, ukuba amanqanaba akho e-Lp(a) aphezulu, kubaluleke kakhulu ukwazisa abantwana bakho, abantakwenu, kunye nabazali bakho ukuba nabo benze olu vavanyo.
Inqaku elikhethekileyo malunga namayeza e-statin
Kukho ingcamango ephosakeleyo phakathi kwabanye yokuba amayeza e-statin cholesterol anokunyusa kancinci amanqanaba e-Lp(a). Oku kunokuba yinyani. Nangona kunjalo, iingenelo ze-statins ekunciphiseni i-LDL cholesterol kunye nokunciphisa umngcipheko wesifo sentliziyo iyonke zingaphezulu kakhulu kwemiphumo emibi enokubakho yokunyuka okuncinci kwamanqanaba e-Lp(a). Ke ngoko, ungaze uyeke ukuthatha i-statin yakho ngaphandle kwengcebiso kagqirha.
Thetha nogqirha wakho malunga nokuvavanywa kwe-Lp(a) yakho. Nangona olu vavanyo lungelulo oluqhelekileyo, banokukuthumela kolu vavanyo emva kokuxoxa ngembali yosapho lwakho kunye nezinto ezinokuba yingozi. Eli linyathelo elibalulekileyo onokulithatha kwimpilo yakho yexesha elizayo.
Umyalezo Wokuya Ekhaya
- I-Lp(a) yingozi efihlakeleyo: Nokuba inqanaba lakho eliqhelekileyo le-cholesterol lilungile, inqanaba eliphezulu le-Lp(a) linokubeka esichengeni sesifo sentliziyo.
- Vavanywa kube kanye ebomini bakho: Ekubeni amanqanaba e-Lp(a) emiselwa kakhulu yimfuza, kudla ngokwanela ukuba olu vavanyo lwenziwe kube kanye ebomini bakho. Thetha nogqirha wakho ngale nto.
- Ungakhathazeki ukuba amazinga akho aphezulu: Ukwazi ukuba amanqanaba akho e-Lp(a) aphezulu kunokukunceda uthathe amanyathelo okunciphisa umngcipheko wesifo sentliziyo sakho siphela.
- Lawula ezinye iingozi: Ukuba i-Lp(a) iphezulu, kubalulekile ukulawula ngokungqongqo zonke ezinye izinto ezinobungozi, ezifana ne-LDL cholesterol, uxinzelelo lwegazi, isifo seswekile, kunye nokutshaya.
- Xelela usapho lwakho: Ekubeni esi sisifo semfuza, ukuba inqanaba lakho le-Lp(a) liphezulu, xelela amalungu osapho lwakho asondeleyo (abazali, abantwana, abantakwenu noodadewabo) kwaye ubakhuthaze ukuba nabo baye kuvavanywa.
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