Kuqhelekile ukuziva uxinezelekile kwaye uxhalabile xa wena okanye umntu omthandayo efunyaniswa ukuba unomhlaza, ingakumbi i-acute leukemia. Ngamaxesha anje, ugqirha wakho uya kuthetha nawe malunga neendlela ezahlukeneyo zonyango. Olunye lonyango lugonyo olubizwa ngokuba yiClofarabine. Igama lophawu lwalo yiClolar. Namhlanje, masithethe ngeli yeza, into eliyenzayo, kunye nento ekufuneka uyiqaphele.
Loluphi uhlobo lonyango oluyiClofarabine?
Ngamafutshane, i-clofarabine liyeza elilwa neeseli zomhlaza. Eli yeza lisetyenziswa, ngakumbi, kwiimeko ze-leukemia ebukhali. Iiseli zomhlaza emzimbeni wethu ziyahlukana kwaye zikhule ngokukhawuleza. Eli yeza linciphisa ukukhula kwezo seli zomhlaza kwaye lilawula ukusasazeka kwazo . Eli licandelo lonyango lomhlaza (i-chemotherapy).
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ukuze iqela lakho lezonyango likunike unyango olungcono nolukhuselekileyo, kubalulekile ukuba bazi iinkcukacha ezipheleleyo zemeko yakho yempilo. Ngoko ke, ngaphambi kokuba uqale unyango nge-clofarabine, qiniseka ukuba uxelele ugqirha wakho ukuba unenye yezi meko zilandelayo:
- Ukuba unesifo sokopha okanye imeko apho igazi lakho lingajiyi lula.
- Ukuba okwangoku unentsholongwane efana nomkhuhlane, ukukhohlela, okanye umkhuhlane.
- Ukuba unesifo sezintso .
- Ukuba wakha waba ne-allergy kwi-clofarabine okanye naliphi na elinye iyeza, ukutya, okanye idayi .
- Ukuba ukhulelwe okanye uceba ukukhulelwa kungekudala .
- Ukuba ungumama oncancisayo .
Musa ukuyifihla le ngcaciso kugqirha, kuba yonke le ngcaciso ibaluleke kakhulu kukhuseleko lwakho.
Uza kunikwa njani eli yeza?
Le ayisiyo pilisi okanye isiraphu onokuyithatha uye nayo ekhaya. Inikwa esibhedlele okanye eklinikhi kuphela. Inikwa njengenaliti emthanjeni ngugqirha okanye umongikazi oqeqeshiweyo.
Ngamanye amaxesha oogqirha banika abantwana abaneminyaka eli-1 ubudala eli yeza, kodwa bakwenza oko ngononophelo olukhulu kunye nokhuseleko olukhethekileyo.
Yintoni omawuyenze ukuba umthamo weyeza unyusiwe?
Ekubeni oku kunikwa esibhedlele, amathuba okuba uphoswe yidosi aphantsi kakhulu. Nangona kunjalo, ukuba uziva ngathi usele kakhulu okanye ukuba ufumana naziphi na iimpawu, yazisa iqela lezonyango ngoko nangoko. Kwimeko engxamisekileyo, ungatsalela umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke eColombo . Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Kubaluleke kakhulu ukusela la mayeza ngemihla emiselweyo nangamaxesha amiselweyo. Ukuba awukwazi ukuya esibhedlele ukuze ufumane idosi yakho ngomhla omiselweyo, musa ukuyiphosa. Fowunela ugqirha wakho ngoko nangoko umxelele. Baza kukuxelela into omawuyenze emva koko.
Amanye amayeza anokusebenza kunye nale mayeza
Kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kungekuphela nje lawo amiselwe ngugqirha wakho, kodwa kunye namayeza okuphelisa iintlungu athengiswa ngaphandle kwemvume kagqirha, iivithamini, amayeza emifuno, kunye nayo nayiphi na enye into oyisebenzisayo. Amanye amayeza anokusebenzisana ne-clofarabine, nto leyo ebangela iziphumo ebezingalindelekanga okanye atshintshe indlela amayeza asebenza ngayo.
Nantsi imizekelo embalwa. Olu luhlu aluphelelanga.
| Udidi lweziyobisi | Imizekelo |
|---|---|
| Izithomalalisi zentlungu kunye nezokunciphisa umkhuhlane | Ii-NSAID ezifana ne-Acetaminophen, i-Aspirin, i-Ibuprofen, ne-Naproxen |
| Amayeza esifo sentliziyo kunye noxinzelelo lwegazi oluphezulu | I-Amiodarone, iMethyldopa, ii-diuretics ezahlukeneyo |
| Amayeza okwehlisa i-cholesterol | I-Atorvastatin, iSimvastatin |
| Amayeza osulelo olwahlukeneyo (amayeza okubulala iintsholongwane/amayeza okulwa nefungus) | I-Amphotericin B, i-Fluconazole, i-Ketoconazole, i-Acyclovir, i-Amoxicillin, i-Gentamicin, i-Tetracycline, i-Vancomycin, i-Rifampin |
| Amayeza okunyanga isifo sokuwa/ukuxhuzula | I-Carbamazepine, iPhenytoin, iValproic acid |
| Amanye amayeza okulwa nomhlaza kunye nokuthintela amajoni omzimba | ICisplatin, iCyclosporine, iMethotrexate |
Izinto ekufuneka uzilumkele xa usebenzisa iyeza
Iqela lezonyango liza kukubeka esweni ngokusondeleyo ngelixa usela eli yeza, kodwa kubalulekile nokuba unikele ingqalelo emzimbeni wakho.
- Uvavanyo lwegazi kunye nokubekwa esweni kwezonyango: Ngeli xesha lonyango, kuya kufuneka ukuba wenze uvavanyo lwegazi rhoqo ukujonga inani leeseli zegazi lakho, ukusebenza kwezintso kunye nesibindi. Musa ukulibaleka eli vavanyo.
- Umngcipheko wokopha: Eli yeza linokunciphisa inani leeseli emzimbeni wakho ezinceda ukujiya kwegazi (iiplatelets). Oku kunokwenza kube nzima nokuba kunqunyulwe kancinci ukuyeka ukopha. Xelela ugqirha wakho ngoko nangoko ukuba ubona nayiphi na imivumbo engaqhelekanga, amabala amfusa, iintsini eziphuma igazi, okanye ukopha impumlo .
- Umngcipheko wokosuleleka: Eli yeza linciphisa amajoni omzimba wakho, ngoko ke unokufumana usulelo ngokulula. Ukuba ufumana iimpawu ezinje ngomkhuhlane, ukugodola, umphimbo obuhlungu, okanye ukukhwehlela , musa ukuzinyanga kwaye utsalele umnxeba ugqirha wakho ngoko nangoko. Nciphisa ukutyelela kwakho iindawo apho abantu bagula khona.
- Iimpendulo ezinzulu zesikhumba: Ngamanye amaxesha, nokuba ziiveki emva kokuba uqalile amayeza, iimpembelelo ezinzulu zesikhumba zinokwenzeka. Ukuba ubona nantoni na efana namadyungudyungu abomvu okanye amfusa eluswini lwakho kunye nomkhuhlane, ukuxobuka kwesikhumba, okanye izilonda emlonyeni wakho, musa ukuyityeshela loo nto. Funa ingcebiso kagqirha ngoko nangoko.
- Ukukhulelwa nokuncancisa: Eli yeza linokubangela iingxaki ezinkulu zokuzalwa komntwana xa lithathwa ngexesha lokukhulelwa . Ngoko ke, kufuneka uphephe ukukhulelwa ngexesha lonyango kwaye kangangeenyanga ezi-6 emva kokuyeka unyango. Kwakhona, kuphephe ukuncancisa ngexesha lonyango kwaye kangangeeveki ezi-2 emva kokuyeka unyango.
- Ukuzala: Eli yeza linokuchaphazela ukuzala kwamadoda nabasetyhini. Oku kuthetha ukuba linokuchaphazela amandla akho okuba nabantwana kwixesha elizayo. Ukuba unenkxalabo malunga noku, thetha nogqirha wakho ngaphambi kokuba uqale unyango.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yale yeza
Njengalo naliphi na iyeza, i-clofarabine inokubangela iziphumo ebezingalindelekanga. Asinguye wonke umntu ozifumanayo. Nangona kunjalo, kubalulekile ukwazi ezo zinokwenzeka.
| Imiphumela | Oko ukuzivayo/ukubonayo |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla. |
| Ukopha okungaqhelekanga | Indle emnyama okanye enegazi, ukuhlanza okufana nekofu egayiweyo, umchamo obomvu/omdaka omnyama, amabala abomvu/amfusa eluswini. |
| Isifo sokuvuza kweCapillary | Intlungu esiswini okanye kwimisipha, ukudinwa kakhulu, ukuquleka, ukuncipha komchamo, ukudumba kwamaqatha, izandla, neenyawo, kunye nobunzima bokuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, amanxeba angapholiyo. |
| Ukulimala kwezintso | Ukuncipha kokuphuma komchamo, ukudumba kwamaqatha, izandla, neenyawo. |
| Ukulimala kwesibindi | Intlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya, isicaphucaphu, ukutyheli kolusu okanye amehlo, umchamo otyheli/omdaka omnyama. |
| Isifo seTumor Lysis (TLS) | Isicaphucaphu, ukuhlanza, urhudo, ukuncipha komchamo, ukubetha kwentliziyo okungahambelaniyo, ukuxhuzula kwemisipha, ukudideka. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Intloko ebuhlungu | - |
| Umnqweno wokutya | - |
| Isicaphucaphu nokuhlanza | - |
| Intlungu ezandleni nasezinyaweni | - |
Umyalezo Wokuya Ekhaya
- I-Clofarabine liyeza elinamandla elinikwa ngemithambo esibhedlele ukunyanga i-leukemia.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngokupheleleyo malunga nawo onke amanye amayeza, iivithamini, kunye nee-allergies ozisebenzisayo.
- Ngexesha lonyango, ukuba ubona naziphi na iimpawu zokopha okungaqhelekanga, usulelo (umkhuhlane, ukukhwehlela), okanye utshintsho olukhulu lolusu, funa ingcebiso kagqirha ngokukhawuleza.
- Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-6 uyekile. Kuphephe nokuncancisa.
- Thetha ngokukhululekileyo nogqirha wakho okanye iqela lezonyango malunga nayo nayiphi na imibuzo, uloyiko, okanye iinkxalabo onokuba nazo. Bakho ukuze bakuncede.
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