Ngaba ugqirha wakho ukunike wena okanye umntu omthandayo iyeza elibizwa ngokuba yiClozapine? Ukuba kunjalo, kubalulekile ukuthetha ngale mayeza ngokweenkcukacha. Ngenxa yokuba oku akufani namayeza aqhelekileyo, kufuna ingqalelo ekhethekileyo, kwaye lunyango olusebenzayo kakhulu. Masithethe ngayo yonke into ngokulula nangokucacileyo.
Loluphi uhlobo lonyango oluyiClozapine?
Ngamafutshane, iClozapine liyeza elisetyenziselwa ukunyanga izifo zengqondo ezifana ne -schizophrenia . Nangona kunjalo, ayilokhetho lokuqala lomntu wonke. Oogqirha badla ngokunika eli yeza xa ezinye iindlela zonyango zingasebenzi kakuhle njengoko bekulindelwe, okanye xa iziphumo ebezingalindelekanga zezinye iindlela zonyango zinganyamezeleki.
Eli lilungu leqela lamayeza abizwa ngokuba yi -'Antipsychotic' . Eli yeza lisebenza ngokulinganisela umsebenzi weekhemikhali ezifana neDopamine kunye neSerotonin, ezinceda ekunxibelelaneni kwemithambo-luvo engqondweni yethu. Ngale ndlela, lizinzisa ingqondo kwaye lilawule iimpawu.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kuya kufuneka abe nomfanekiso opheleleyo wempilo yakho. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho ngazo.
- Ukuba wakha waba ne-allergy kwiClozapine okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba unesifo seswekile okanye ukuba kukho umntu kusapho lwakho onaso.
- Ukuba uneemeko ezifana nesifo sentliziyo , i-cholesterol ephezulu, uxinzelelo lwegazi oluphezulu/oluphantsi, okanye ukubetha kwentliziyo okungaqhelekanga.
- Ukuba ukhe wahlaselwa sistroke ngaphambili.
- Ukuba unesifo sesibindi okanye sezintso .
- Ukuba unesifo esifana nokubalwa kwegazi okuphantsi , iiseli ezimhlophe zegazi ezisezantsi, iiseli ezibomvu zegazi ezisezantsi, okanye iiplatelets ezisezantsi.
- Ukuba uhlala unesithukuthezi okanye uvalekile amathumbu akho.
- Ukuba unesifo sokuxhuzula okanye ukuxhuzula.
- Ukuba unesifo sikaParkinson .
- Ukuba unengxaki yokukhumbula efana ne-dementia.
- Ukuba unengxaki yeprostate okanye ubunzima bokuchama.
- Ukuba unesifo samehlo i-glaucoma.
- Ukuba unengxaki yokuginya into ethile.
- Ukuba ungumntu otshayayo. (Oku kubaluleke kakhulu, siza kuthetha ngako kamva).
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa.
Ukuba kukho nantoni na ekolu luhlu ehambelana nawe, musa ukuyifihla kugqirha wakho. Ibaluleke kakhulu kukhuseleko lwakho.
Ndingayisebenzisa njani kanye kanye le yeza?
- Sela idosi oyinikwe ngugqirha wakho, kanye njengoko uyalelwe, nangexesha elifanelekileyo. Ginya ipilisi ngeglasi yamanzi.
- Akunamsebenzi nokuba uyithatha ngaphambi okanye emva kokutya.
- Musa ukuthatha okungaphezulu koko ugqirha akuxelele kona, okanye ukuthathe ngaphambi kwexesha elimiselweyo.
- Eyona nto ibalulekileyo: Musa ukuyeka ukuthatha eli yeza ngequbuliso nangasiphi na isizathu ngaphandle kwengcebiso kagqirha. Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga ezibi kakhulu. Ukuba kufuneka uyeke ukuthatha eli yeza, yenza njalo kancinci kancinci, wehlise umthamo, kwaye kuphela phantsi kweliso likagqirha.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza angaphezu kwedosi emiselweyo, fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kuza kufuneka uyithathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini ukuze ubuyisele idosi oyiphosileyo.
Isilumkiso Esikhethekileyo: Ukuba awukwazi ukusela amayeza akho kangangeentsuku ezingaphezu kwezimbini (iiyure ezingama-48), musa ukuqala kwakhona ngedosi efanayo. Qiniseka ukuba ufowunela ugqirha wakho ukuze akunike ingcebiso.
Ezinye izinto ezinokubangela iingxaki ngale mithi
I-Clozapine liyeza elinokunxibelelana nezinye iziyobisi, ukutya, nezinto. Ngoko ke kufuneka uxelele ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza emifuno).
| Udidi lweziyobisi/iziyobisi | Imizekelo kunye neenkcazo ezilula |
|---|---|
| Izinto ongafanele uzithathe | |
| Amanye amayeza | Amayeza anje ngeCisapride, iPimozide, iThioridazine. Ugqirha wakho uza kukwazisa ngale nto. |
| Izinto ezinokubangela iingxaki kwaye kufuneka zithathwe phantsi kwengcebiso kagqirha | |
| Utywala | Kuphephe ukusela utywala ngelixa usebenzisa eli yeza. Linokunyusa ukozela kunye nesiyezi. |
| I-Caffeine | I-caffeine, efumaneka kwikofu, iti, nakwezinye iziselo ezibandayo, inokuchaphazela amanqanaba e-clozapine. Xelela ugqirha wakho malunga nobungakanani obuselayo. |
| Ukutshaya | Ukutshaya kunokunciphisa inqanaba le-clozapine egazini lakho. Ukuba uyatshaya okanye ucinga ngokuyeka, qiniseka ukuba uxelele ugqirha wakho. Umthamo wakho unokufuna ukulungiswa. |
| Amanye amayeza | Amanye amayeza omkhuhlane, i-allergies, ukudakumba, ukungalali, isifo sokuwa, usulelo lwefungus, kunye noxinzelelo lwegazi oluphezulu anokubangela le ngxaki. |
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
Ziqaphele ezi zinto ukuqinisekisa ukhuseleko lwakho xa usebenzisa i-clozapine.
Uvavanyo lwegazi olunyanzelekileyo
Le yeyona nto ibalulekileyo. Xa uqala ukuthatha i-clozapine, kufuneka uvavanye igazi kube kanye ngeveki kwiiveki ezimbalwa zokuqala. Oku kukujonga inani leeseli ezimhlophe egazini lakho. Ngamanye amaxesha eli yeza linokubangela ukuba inani leeseli ezimhlophe egazini lakho lehle ngendlela eyingozi. Oku kunokwenza kube nzima kuwe ukulwa nosulelo. Ukuba inani legazi lakho lilungile emva kweenyanga ezi-6, ugqirha wakho uya kucebisa ukuba wenze olu vavanyo rhoqo kwiiveki ezimbini.
Ukozela kunye nesiyezi
Eli yeza linokukwenza uzive ulele kwaye unesiyezi. Ngoko ke, ziphephe izinto ezifuna ulumke, njengokuqhuba okanye ukusebenzisa oomatshini, ude wazi ukuba eli yeza likuchaphazela njani. Musa ukuma okanye ukuhlala ngequbuliso.
Ukuqhinwa
Ukuqhina kwesisu kuqhelekile xa usebenzisa eli yeza, kodwa kunokuba nzima kakhulu. Ukuba awunayo intshukumo yokuhambisa isisu emva kweentsuku ezi-2-3, okanye ukuba ufumana iimpawu ezifana nokuqunjelwa, iintlungu zesisu, okanye isicaphucaphu, tsalela umnxeba ugqirha wakho ngoko nangoko. Sela amanzi amaninzi.
Ulawulo lobushushu bomzimba
Eli yeza lisenokunciphisa amandla akho okunyamezela ukubanda kakhulu kunye nobushushu. Ngoko ke, nxiba ngokufanelekileyo xa kubanda. Nciphisa ukuvezwa lilanga kunye nokuzibhokoxa xa kushushu. Sela amanzi amaninzi.
Iziphumo ebezingalindelekanga ezinokubakho zeyeza
Njengazo zonke amayeza, le inokuba nemiphumo emibi. Eminye yayo iyingozi, eminye yayo ixhaphakile.
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho okanye kwi-ETU ngoko nangoko | |
|---|---|
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu, izilonda emlonyeni (ezi zisenokuba ziimpawu zokuba inani leeseli ezimhlophe zegazi liphantsi). |
| Iimpawu zentliziyo | Intlungu esifubeni, ubunzima bokuphefumla, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukudumba kwemilenze. |
| Ukuqhinwa okukhulu | Intlungu ebuhlungu esiswini, ukudumba, ukuhlanza. |
| Ukuxhuzula | Ukuba umzimba uyangcangcazela ngendlela engalawulekiyo. |
| Iimpawu ze-NMS | Umkhuhlane ophezulu, ukuqina kwemisipha, ukubila okugqithisileyo, kunye nokudideka. (Isifo se-Neuroleptic Malignant) |
| Ii-aleji | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi. |
| Ngokwesiqhelo ayisiyonto imbi kangako, kodwa xelela ugqirha wakho ukuba iyaqhubeka. | |
| Ukutyiwa kakhulu ngamathe | Oku kunokwenzeka ingakumbi ebusuku. |
| Ukozela, isiyezi | Oku kunokuncipha njengoko umzimba uqhelana namayeza. |
| Ukutyeba kwakho | Thetha nogqirha wakho malunga nokutya kunye nokuzilolonga. |
| Intloko ebuhlungu | Inokwenzeka kancinci. |
Umyalezo Wokuya Ekhaya
- I-Clozapine lunyango olusebenzayo kakhulu kwizifo zengqondo ezingasabelanga kwamanye amayeza, kodwa kufuneka ithathwe phantsi kweliso elingqongqo lezonyango.
- Ungaze uyeke ukuthatha amayeza okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha.
- Uvavanyo lwegazi lweveki nganye okanye lweveki ezimbini lubalulekile ukuze ukhuseleke. Musa ukuluphosa.
- Xelela ugqirha wakho ngazo zonke ezinye iindlela ozithathelayo, nokuba uyatshaya okanye awutshayi, kunye nazo zonke iimeko zakho zempilo.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ufumanisa iimpawu ezilumkisayo ezifana nomkhuhlane kunye nomphimbo obuhlungu, iintlungu eziqatha esifubeni, okanye ukuqhina okukhulu.
- Ukuba uphoswa ziinyanga ezingaphezu kweentsuku ezimbini usebenzisa amayeza, thetha nogqirha wakho ngaphambi kokuba uqale kwakhona.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Iipilisi zeClozapine (Clozaril) zezona ndlela zokugqibela zokuthintela isifo?
Eli liyeza lokuqala lesizukulwana esitsha (elingaqhelekanga) elinamandla kakhulu elenziwe ukulawula isifo sengqondo esinzima esibizwa ngokuba yi-'Schizophrenia'! Eli chiza alinikwa wonke umntu, lisetyenziswa kuphela kwizigulane ezinzima kakhulu (ezinganyangekiyo kunyango) kunye nezigulane ezizibulalayo/ezinobundlongondlongo, ezibonakala ngathi azikwazi ukuva amazwi angaqhelekanga esigulana nangona kukho amanye amayeza.
💬 Yintoni ekhethekileyo ngale (Clozapine) eyenza isebenze ngaphezu kwamanye amayeza?
Amanye amayeza engqondo avimba ii-receptors ze-dopamine (D2) engqondweni. Emva koko isigulane siba lukhuni njengerobhothi. Kodwa le Clozapine ayivali kangako ii-receptors ze-dopamine D2, endaweni yoko ivimba kakhulu i-serotonin (5HT2A) kunye nezinye ii-receptors ze-D4 engqondweni. Yiyo loo nto njengoko esi sifo siphucuka, asinaso eso siphumo siqinileyo (EPS) kwaphela!
💬 Kutheni kubalulekile ukujonga iiseli ezimhlophe zegazi zabantu abathatha le pilisi (iClozapine)?
Le yeyona ngozi iyingozi nebulalayo yale yeza! (Isilumkiso seBlack Box). Xa usela eli yeza, 'iiseli zegazi ezimhlophe (iiNeutrophils)' zezigulane ezithile ezilwa nezifo emizimbeni yazo zinokutshatyalaliswa nge-100% kwaye zincitshiswe ngokupheleleyo zibe yi-zero (i-Agranulocytosis)! Emva koko nentsholongwane encinci yomkhuhlane inokubulala isigulane. Ke ngoko, 'uvavanyo lwegazi lweveki (i-ANC)' kufuneka lwenziwe kwiinyanga ezintandathu zonke zokuthatha eli yeza!
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho