Ingaba umzimba wakho uya ukhula kwaye ubuso bakho bujikeleza njengenyanga epheleleyo? Masithethe nge-'Cushing's Syndrome'!

Ngaba ukhe waphawula kutshanje ukuba imo yomzimba wakho itshintshile kancinci, ingakumbi emzimbeni wakho ongasentla nasesiswini, kwaye ubuso bakho buye baba ngqukuva njengenyanga epheleleyo? Mhlawumbi uneqhuma elincinci lamafutha elikhula ngasemva kwentamo yakho. Ezi ayizizo izinto ezingaqhelekanga nje. Emva kwezi mpawu kusenokuba kukho imeko yehomoni ebizwa ngokuba yiCushing's Syndrome . Ungakhathazeki, le yimeko enokunyangwa rhoqo. Masithethe ngale nto ngokulula, ngendlela wonke umntu anokuyiqonda.

Ngamafutshane, yintoni iCushing's Syndrome?

I-Cushing's Syndrome, okanye i-hypercortisolism , yimeko eyenzeka xa imizimba yethu ivelisa i-hormone cortisol eninzi kakhulu. Ngoku usenokuba uzibuza ukuba yintoni i-cortisol. I-Cortisol yi-hormone ebaluleke kakhulu eveliswa zii-glands ezimbini ezincinci ezikwi-adrenal glands zethu. Yenza umsebenzi omninzi emizimbeni yethu.

• Ilawula uxinzelelo lwegazi .
• Ilawula amanqanaba eswekile egazini.
• Inciphisa ukudumba emzimbeni.
• Inceda ekuguquleni ukutya esikutyayo kube ngamandla.

Khawucinge nje, konke oku kwenzeka xa kukho inani elifanelekileyo le-cortisol. Kodwa xa le hormone iba ninzi kakhulu, ukusebenza kwezinye iinkqubo emzimbeni kuqala ukuba buthathaka. Yiloo nto siyibiza ngokuba yiCushing's Syndrome. Le meko ixhaphake kakhulu kwabasetyhini kunamadoda. Ixhaphake kakhulu kubantu abaphakathi kweminyaka engama-25 ukuya kwengama-40 ubudala.

Ziziphi izizathu eziphambili zeCushing's Syndrome?

Kunokubakho izizathu ezahlukeneyo zoku. Makhe sijonge ezona ziphambili.

1. Ukusetyenziswa kwamayeza (eyona nto ixhaphakileyo)

Eyona nto ixhaphakileyo yale meko kukusetyenziswa ixesha elide kwamayeza abizwa ngokuba yi -glucocorticoids . La adla ngokubizwa ngokuba yi -corticosteroids okanye nje i-steroids . Umzekelo, i-prednisoneUngawathatha amayeza abizwayo. Oogqirha bacebisa la mayeza kwiimeko ezifana ne-asthma, i-rheumatoid arthritis, i-lupus, okanye emva kokufakelwa ilungu lomzimba. La ngamayeza anamandla kakhulu alawula ukudumba. Nangona kunjalo, xa la mayeza esetyenziswa ixesha elide, i-Cushing's Syndrome inokwenzeka njengesiphumo esibi. Kwakhona, le meko ingenzeka ngenxa yokujova rhoqo kwe-steroid kwizinto ezifana nentlungu yamalungu kunye nentlungu yomqolo. Le meko inqabile kakhulu ngenxa yee-steroid creams ezisetyenziselwa izifo zesikhumba, kodwa inokwenzeka.

2. Iithumba ezenzeka emzimbeni

Amanqanaba e-cortisol anokunyuka nasemizimbeni yethu. Isizathu soku ziintlobo ezahlukeneyo zeethumba ezikhula emzimbeni.

• IiTumors zePituitary: Ukuba kuvela ithumba elincinci kwi-pituitary gland esezantsi kwengqondo yethu, liqala ukuvelisa i-hormone ebizwa ngokuba yi-ACTH (i-Adrenocorticotropic hormone) . Le hormone ye-ACTH yiyo enika imiqondiso kwi-adrenal glands ukuba ivelise i-cortisol . Ngoko ke xa i-ACTH isanda, imveliso ye-cortisol nayo iyanda ngokuzenzekelayo. Sikwabiza le meko ngokuthi yiCushing's Disease .
• Ii-Adrenal Tumors: Ngamanye amaxesha i-tumor inokukhula kwi-adrenal gland ngokwayo, enokuvelisa ngokuthe ngqo i-cortisol egqithisileyo.
• Ii-Ectopic Tumors: Kunqabile kakhulu ukuba i-tumor ikhule kwindawo apho i-ACTH hormone ingaveliswanga khona, njengemiphunga , i-pancreas , okanye i-thyroid gland , ize iqale ukuvelisa i-ACTH.

Ezi thumba zinokuba ngumhlaza okanye zingabi ngumhlaza.

Zithini iimpawu zesi sifo?

Iimpawu zingahluka kumntu nomntu, kodwa kukho iimpawu eziqhelekileyo ezinokubonakala xa isifo siqhubela phambili. Makhe sijonge ezi kwitheyibhile. Ukongeza, abanye abantu banokubona amabala okolula amfusa okanye apinki esiswini, emathangeni, ezingalweni nasesifubeni. Njengoko amathambo esiya eba buthathaka, banokufumana iintlungu zomqolo okanye iimbambo ezaphukileyo, kungekuphela nje xa begoba, bephakamisa iintsimbi, kodwa naxa bephakama esitulweni. Ukuba abantwana abancinci bakhula nale meko, ukukhula kwabo kuya kucotha kakhulu, kwaye banokuba nokutyeba kakhulu.

Ugqirha usifumanisa njani esi sifo?

Kungathatha utyelelo olude ukuze ugqirha wakho aqinisekise ukuba unesifo. Okokuqala, uza kukuhlola ngokwasemzimbeni aze akubuze imibuzo embalwa.

• Zithini iimpawu zakho?
• Uqale nini ukuzibona ezi zinto?
• Ngawaphi amayeza owasebenzisayo? (Ingakumbi ii-steroids)
• Ngaba uziva utshintsho engqondweni yakho?

Ngokusekelwe kolu lwazi, ukuba kukho urhanelwa ukuba uCushing's Syndrome, ugqirha uya kucebisa iimvavanyo ezininzi.

• Uvavanyo lwe-cortisol olungenamchamo oluthatha iiyure ezingama-24: Lulinganisa inqanaba le-cortisol kumchamo oqokelelweyo kwixesha leeyure ezingama-24.
• Uvavanyo lokuncitshiswa kweDexamethasone: Ipilisi ye-steroid enesilinganiselo esiphantsi inikwa malunga nentsimbi ye-11 ebusuku, kwaye uvavanyo lwegazi lwenziwa kusasa olulandelayo ukuze kubonwe ukuba ingakanani na i-cortisol eveliswa ngumzimba.
• Inqanaba le-cortisol yamathe ebusuku: Lilinganisa amanqanaba e-cortisol kwisampuli yamathe ethathwe ebusuku.

Ukuba ezi mvavanyo ziqinisekisa ukuba uneCushing's Syndrome, inyathelo elilandelayo kukufumana unobangela . Ukuze wenze oku, ingcali ingenza ezinye iimvavanyo ezininzi. Umzekelo, iimvavanyo zegazi ukujonga amanqanaba e-ACTH hormone, ii-CT okanye ii-MRI scans.

Zithini iindlela zonyango zoku?

Indlela yonyango ixhomekeke kwinto ebangela imeko yakho.

• • Ukuba unobangela ngamayeza e-steroid: Ugqirha wakho uza kuqala ukunciphisa kancinci idosi yakho ye-steroid njengoko esinye isifo sakho (umz. i-asthma, i-arthritis) silawulwa.

Okubaluleke kakhulu: Musa ukuyeka ukuthatha ii-steroids ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga ezibi kakhulu.

• Ukuba unobangela sisimila: Kusenokufuneka utyando ukuze kususwe isimila. Ngamanye amaxesha, unyango lwemitha lunokunikwa ukongeza kutyando.
• Ezinye iindlela zonyango: Ukuba utyando okanye unyango lwemitha aluphumelelanga, amayeza anokunikwa ukulawula ukuveliswa kwe-cortisol. Nangona kunjalo, la mayeza anokuba nemiphumo emibi, ngoko ke kufuneka athathwe phantsi kweliso likagqirha.

Ungayitshintsha njani indlela yokuphila kunye nokutya kunye nonyango?

Ngelixa unyangwa, ukulungisa indlela ophila ngayo kunye nokutya okutyayo kunokukunceda kakhulu ukulawula iimpawu zakho.

• Yitya ukutya okunempilo:
• Yitya ukutya okutyebileyo kwi -calcium kunye ne-vitamin D. Le meko yenza amathambo abe buthathaka. Ubisi, iyogathi, itshizi, imifuno eluhlaza, kunye nentlanzi encinci (eneethambo) zilungile.
• Nciphisa ukutya okune- sodium eninzi kunye neoyile/amafutha . Oku kunokukhokelela kuxinzelelo lwegazi oluphezulu kunye nokunyuka kobunzima.
• Lawula iintlungu:Izinto ezinje ngokuhlamba ngamanzi ashushu, ukuphululwa umzimba kancinci, kunye nokwenza i-water aerobics zinokunceda ekunciphiseni iintlungu zemisipha.
• Impilo yengqondo: Le meko inokuba yingozi. Thetha nosapho lwakho kunye nabahlobo ngale nto. Cela inkxaso yabo. Ukuba kuyimfuneko, funa uncedo kumcebisi. Ungacela ulwalathiso kugqirha wakho.

I-Cushing's Syndrome, i-cortisol, ii-steroids, iihomoni, uxinzelelo lwegazi oluphezulu, isifo seswekile, ukuwohloka komzimba, ubuso benyanga, i-buffalo hump, i-pituitary gland, i-adrenal gland, iimpawu ze-Cushing's syndrome, unyango lwe-Cushing's syndrome