Kuqhelekile ukuba uzive usoyika kwaye unexhala xa uza kuqala unyango lomhlaza. Kodwa xa usazi kakuhle amayeza owasebenzisayo nendlela achaphazela ngayo umzimba wakho, olo loyiko lunokuncipha kakhulu. Namhlanje sithetha ngeyeza elibizwa ngokuba yiDacarbazine, elisetyenziselwa unyango lomhlaza olunjalo. Makhe sithethe ngale nto ngendlela elula ukuze uqonde.
Luhlobo luni lweyeza iDacarbazine?
Ngamafutshane, i-dacarbazine luhlobo lweyeza le-chemotherapy . I-Chemotherapy luhlobo lweyeza elinamandla elinikwayo ukunqanda ukukhula kweeseli zomhlaza okanye ukuzibulala.
Eli yeza lisetyenziswa kakhulu ukunyanga:
- Umhlaza wolusu
- Idityaniswe namanye amayeza okunyanga isifo sikaHodgkin
Eli yeza alinikwa wena ekhaya. Linikwa esibhedlele okanye ekliniki ngugqirha okanye umongikazi oqeqeshwe ngokukodwa ukulinika. Eli yeza linikwa emzimbeni ngokulifaka emthanjeni okanye ngokulifaka emthanjeni, njenge-saline .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Kubaluleke kakhulu ukuba ugqirha wakho azi kakuhle imeko yakho yempilo ngaphambi kokuba aqalise olu nyango. Ngoko ke, ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba uxelele ugqirha wakho .
| Imeko ekufuneka uyixele | Kutheni oko kubalulekile? |
|---|---|
| Usulelo lwangoku (umz., usulelo lwentsholongwane olufana ne-chickenpox, i-herpes) | Ngenxa yokuba eli yeza linciphisa amajoni omzimba, izifo ezikhoyo zinokuba mandundu. |
| Isifo sezintso okanye sesibindi | Ngenxa yokuba la malungu ebandakanyeka kwinkqubo yokususa iziyobisi emzimbeni, kubalulekile ukwazi umsebenzi wazo. |
| Iimeko ezifana neeseli ezibomvu zegazi ezisezantsi, iiseli ezimhlophe zegazi, okanye iiplatelets | I-Dacarbazine inokunciphisa ngakumbi inani lezi seli, ngoko ke kubalulekile ukuba uqaphele imeko yangoku. |
| Ukuba usandul' ukufumana unyango lwe-radiation | Ekubeni zombini unyango lwemitha kunye ne-chemotherapy zichaphazela umzimba, ugqirha kufuneka azi ngale nto. |
| Ukuba une-allergies kweli yeza okanye amanye amayeza okanye ukutya | Oku kubaluleke kakhulu ukuthintela ukusabela okunzulu kwe-allergy. |
| Ukuba ukhulelwe okanye uzama ukukhulelwa | Oku kubaluleke kakhulu. Eli yeza linokubangela ingozi enkulu kumntwana ongekazalwa. |
| Ukuba ungumama oncancisayo | Ukuncancisa kufuneka kuphetshwe xa usebenzisa unyango, kuba iyeza linokudlula kubisi lwebele kwaye lonakalise umntwana. |
Izinto ekufuneka siziqwalasele ngokukodwa xa sithatha eli yeza:
Udinga ukunyamekela umzimba wakho ngakumbi kulo lonke ixesha lonyango.
Uvavanyo lwegazi rhoqo
Ngelixa usela eli yeza, ugqirha wakho uya kuyalela uvavanyo lwegazi rhoqo. Olu lwenzelwe ukujonga indlela eli chiza elichaphazela ngayo umzimba wakho kunye neeseli zakho zegazi. Musa ukuliphosa eli vavanyo.
Ukungonwabi
Kuqhelekile ukuziva ungakhululekanga kwaye udiniwe xa usebenzisa i-chemotherapy. Oku kungenxa yokuba la mayeza achaphazela zombini iiseli zomhlaza kunye neeseli eziphilileyo ngandlela thile. Ngoko ke, musa ukuyeka unyango kuba nje ungaziva kakuhle. Kubalulekile ukugqiba umjikelo wonyango omiselweyo ngaphandle kokuba ugqirha wakho ekuxelela ukuba uyeke .
Lumka kwiintsholongwane.
Eli yeza linokunciphisa inani leeseli ezimhlophe zegazi emzimbeni ezilwa nezifo, nto leyo eyonyusa umngcipheko wokufumana usulelo .
Ukuba ubonakalisa iimpawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, okanye impumlo egobhozayo, musa ukuzinyanga kwaye utsalele ugqirha wakho umnxeba ngoko nangoko.Ngeli xesha, nciphisa ukuya kwiindawo apho kukho abantu abagulayo nakwiindawo ezixineneyo kangangoko unako.
Ukopha kunye nokudumba
Inani leeplatelet, ezinceda ekuqhekekeni kwegazi, linokuncipha. Oku kunokunyusa umngcipheko wokopha nokukrweleka . Xelela ugqirha wakho ukuba ubona naluphi na ukopha okungaqhelekanga, njengokukrweleka okungachazwanga, amabala amancinci abomvu eluswini, igazi kwindle yakho, okanye igazi kumchamo wakho.
Ziphephe ukukhulelwa!
Eyona nto ibalulekileyo kukuphepha ukukhulelwa ngokupheleleyo ngexesha nasemva kolu nyango logama nje ugqirha wakho ekuxelele ukuba wenze njalo. Eli yeza linokulimaza kakhulu usana olungekazalwa. Kwakhona, oomama abancancisayo kufuneka baphephe ukuncancisa usana lwabo ngelixa bethatha olu nyango. Ukuba unemibuzo malunga noku, thetha nogqirha wakho ngokukhululekileyo.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, i-dacarbazine inokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Itheyibhile engasezantsi inika umfanekiso ocacileyo wezi zinto.
| Iziphumo ebezingalindelekanga ezinokubakho zeDacarbazine | |
|---|---|
| 🚨 Izinto ekufuneka uzixelele ugqirha wakho ngoko nangoko | |
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kwemilebe/ulwimi/ubuso, ubunzima bokuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu xa uchama. |
| Iimpawu zeplatelets ezisezantsi okanye ukopha | Ukudumba okungachazwanga emzimbeni, ubomvu, amabala amancinci eluswini, indle emnyama, kunye negazi emchameni. |
| Inani eliphantsi leeseli ezibomvu zegazi (i-anemia) | Ndiziva ndidiniwe ngendlela engaqhelekanga, ndingenabomi, ndibuthathaka, ndingenawo namehlo aluhlaza okwesibhakabhaka. |
| Ezinye iimpawu ezinzulu | Ubunzima bokuphefumla, iintlungu zemisipha, iintlungu apho iyeza lifakwe khona, ukuhlanza, ukutyheli kwamehlo okanye ulusu, utshintsho kubungakanani bomchamo owuvelisayo. |
| 🙂 Izinto eziqhelekileyo, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki zenkqubo yokugaya ukutya | Isicaphucaphu, isisu esibuhlungu, urhudo, ukungabi namdla wokutya. |
| Ezinye iziphumo ezincinci | Ukulahleka kweenwele, ulusu lunobuthathaka kwilanga. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, nceda wazise ugqirha wakho ngazo.
Kuthekani ukuba ndiphoswa yidosi ethile ndize ndithathe amayeza amaninzi kakhulu?
Kubaluleke kakhulu ukusela amayeza akho e-chemotherapy ngosuku olucwangcisiweyo nangexesha elicwangcisiweyo. Ukungaphumeleli ukwenza njalo kunokuchaphazela impumelelo yonyango. Ukuba awukwazi ukuya ngosuku olucwangcisiweyo, tsalela umnxeba ugqirha wakho ngoko nangoko .
Ekubeni eli yeza lingasetyenziswa ekhaya, umngcipheko wokusebenzisa kakhulu eli yeza uphantsi. Nangona kunjalo, ukuba ucinga ukuba ukhe wachaphazeleka yilo nangayiphi na indlela, kufuneka utsalele umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Umyalezo Wokuya Ekhaya
- I-Dacarbazine liyeza elinamandla lokulwa nomhlaza elinikwa ngemithambo yegazi ngabasebenzi abaqeqeshwe ngokukodwa esibhedlele.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo, amayeza owasebenzisayo, kunye nee-allergies.
- Soloko ujonge iimpawu ezinje ngomkhuhlane, ukopha okungaqhelekanga, kunye nokukrweleka. Ukuba ubona nayiphi na kwezi, bona ugqirha ngokukhawuleza.
- Kuphephe ukukhulelwa nokuncancisa ngokupheleleyo ngexesha lonyango.
- Nangona kuyinto eqhelekileyo ukuziva ungakhululekanga, yazisa ugqirha wakho ngayo nayiphi na imiphumo emibi eqatha okanye engapheliyo.
- Ukulandela imiyalelo kagqirha ngokuchanekileyo kubalulekile ukuze unyango luphumelele.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Isetyenziselwa ntoni iDacarbazine (DTIC-Dome)?
Le ayisiyopilisi eqhelekileyo! Eli liyeza elinamandla kakhulu le-chemotherapy (i-Alkylating agent) elifakwa ngqo emthanjeni wesigulane (IV Injection) kwisibhedlele somhlaza ukuze kutshatyalaliswe i-'Hodgkin's Lymphoma' enzima kwaye kusasazwe kakhulu umhlaza wolusu (iMetastatic Melanoma)!
💬 Olu gonyo lwekhemikhali (iDacarbazine / iChemo) luzitshabalalisa njani ngokupheleleyo iiseli zomhlaza xa lungena emizimbeni yethu?
Ukuze iseli yomhlaza yahlulwe/iphinde ivelise, kufuneka yenze i-'DNA' entsha. Eli yeza lingena egazini lethu, kwaye isibindi sivuselela inxalenye yalo (i-Active metabolite - MTIC). Emva koko lingena ngqo kwiiseli zomhlaza, lijikeleze uthotho olwenza i-DNA (ii-GC base pairs) kwaye liyivale (i-Alkylation / i-Cross-linking). Xa i-DNA ibethwa/isasazeka, iseli yomhlaza iyaqhuma ize ife kanye apho ngokungathi idutyulwe.
💬 Ukufa Komhlaza Zeziphi iingozi eziyingozi kakhulu (Izilumkiso zeBlack Box) ezijongene nomguli xa enikwa olu gonyo?
Eyona ngozi ibulalayo kwisigulana kukuba oku kubangela ukutshatyalaliswa kwe-100% yomongo odala igazi (Bone Marrow Suppression)! Xa iiseli zegazi zilahlekile, nokuba umkhuhlane omncinci unokukhokelela kwi-pneumonia/ukuhlanza igazi kwaye isigulana sinokufa. Enye ingozi enkulu kukuba oku kubangela ukuba imithambo yegazi esibindini ivaleke (Hepatic Necrosis / VOD) kwaye isibindi sibole. Kwakhona, ukuhlanza/isicaphucaphu esinganyamezelekiyo ngokuqinisekileyo kuya kwenzeka ngomhla wokufakwa kwesi sitofu.
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