Ingaba kukho indawo engaqhelekanga eluswini lwakho? Isenokuba yiDFSP (Dermatofibrosarcoma Protuberans)!

Ngaba wakha waphawula iqhuma elincinci okanye ukutshintsha kombala eluswini lwakho? Ngamanye amaxesha asiyihoyi kangako loo nto, akunjalo? Kodwa ngamanye amaxesha nento encinci njengale inokuba yinto ekufuneka ixhalatyelwe. Namhlanje, siza kuthetha ngohlobo lomhlaza wolusu olungaqhelekanga kodwa olubalulekileyo. Lubizwa ngokuba yiDermatofibrosarcoma Protuberans , okanye iDFSP ngamafutshane.

Yintoni i-DFSP (i-Dermatofibrosarcoma Protuberans)?

Ngamafutshane, i-DFSP luhlobo lomhlaza wolusu olukhula kancinci, kodwa olungaqhelekanga. Luqala kumaleko ophakathi wolusu lwethu, i-dermis . Usenokuva ugqirha eyibiza ngokuba yi-DFSP.

Ngenxa yokuba lo ngumhlaza okhula kancinci, awufane usasazeke kwamanye amalungu omzimba. Nangona kunjalo, ayilocebo lilungileyo ukuwutyeshela. Kubaluleke kakhulu ukufumana unyango olufanelekileyo nokususa eli tumor. Kulapho kuphela apho umhlaza ungayeki ukubuya (ukuphinda ubuye) okanye usasazeke kwamanye amalungu omzimba (umhlaza osasazekayo). Ngonyango olufanelekileyo, umntu one-DFSP unethuba elihle kakhulu lokuchacha.

Ingaba le DFSP yithumba nje? Okanye ngumhlaza?

Hayi, i-DFSP ayisiyonto nje ebangela isifo esingenabungozi. Yimeko embi kakhulu . Ukuchaneka, luhlobo lomhlaza wezicubu ezithambileyo, uhlobo lwe -sarcoma yezicubu ezithambileyo . Ii-Sarcomas ziinhlungu ezenzeka kwiindawo ezifana nezihlunu, amafutha, kunye nolusu. Ngamanye amaxesha, zinokuchaphazela namathambo.

Ngaba i-DFSP ingasasazeka (i-metastasize) kwezinye iindawo zomzimba?

I-DFSP ayisoloko iluhlobo lomhlaza olusasazeka ngokukhawuleza emzimbeni wonke. Nangona kunjalo, kunqabile kakhulu, malunga nomntu omnye kwabangama-20 abane -DFSP unokusasaza umhlaza ngaphaya kwendawo owaqala kuyo. Oku kubizwa ngokuba ngumhlaza osasazekayo .

Oku kunokwenzeka ukuba kusasazeka ukuba akunyangwa, okanye ukuba umhlaza usasazeke nzulu eluswini, kwizicubu ezinamafutha kunye nemisipha.

Enye into kukuba, nangona unobangela ungaziwa, ukuba i-DFSP ikhula ngexesha lokukhulelwa, inokuba mandundu ngakumbi.

Kwakhona, inani elincinci labantu abane-DFSP linokuba nohlobo olunamandla nolusasazeka ngokukhawuleza olubizwa ngokuba yi -fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS) . Nokuba ezi thumba ze-DFSP-FS zisusiwe ngotyando, zinokuphinda zibuye kwaye zinokusasazeka kwezinye iindawo.

Ixhaphake kangakanani le meko ibizwa ngokuba yi-DFSP?

I-DFSP luhlobo lomhlaza olungaqhelekanga kakhulu. Ehlabathini lonke, ichaphazela abantu abamalunga nesine kuphela kwisigidi sabantu ngonyaka. I-DFSP ibandakanya phakathi kwe-1% kunye ne-6% yazo zonke ii-sarcomas zezicubu ezithambileyo.

Lo mhlaza uxhaphake kakhulu kubantu abadala abaneminyaka ephakathi kwama-20 nama-50. Nangona kunjalo, abantwana abancinci nabo banokuba nalo mhlaza wolusu. Abanye abantwana banokuba ne-DFSP xa bezalwa. Uphando lubonise ukuba abantu abamnyama banamathuba amancinci okuba nawo kunabanye abantu bezinye iintlanga.

Ziziphi iintlobo eziphambili ze-DFSP?

Iingcali zezifo, oogqirha abahlola izicwili zomzimba phantsi kwe-microscope, banokukuxelela ukuba loluphi uhlobo lwe-DFSP onayo ngokuhlola iiseli. Kukho iintlobo ezininzi eziphambili:

• Ii-tumor zaseBednar (ezaziwa ngokuba yi-DFSP enemibala): Ezi ntlobo zeeseli ziqulathe i-melanin eninzi, umbala onika ulusu umbala walo. Yingakho ezi tumor zinokubonakala ngemibala eyahlukeneyo, kuquka obomvu, omdaka, oluhlaza okwesibhakabhaka, nomfusa. Olu hlobo lubandakanya malunga ne-5% yokuxilongwa kwe-DFSP.
• I-Giant cell fibroblastoma: Olu hlobo lubonakala ngokubakho kwee-giant cells. Olu hlobo lukwabizwa ngokuba yi-juvenile DFSP kuba luhlala lusenzeka ebantwaneni nakubantu abadala abancinci.
• I-Fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS): Njengoko bekutshiwo ngaphambili, olu luhlobo lwe-sarcoma yezicubu ezithambileyo olunoburhalarhume, olusasazeka ngokukhawuleza.
• IiMyxoid DFSP: Ezi zenziwe ngohlobo olungaqhelekanga lwezicubu ezidityanisiweyo ezibizwa ngokuba yimyxoid stroma. Olu hlobo lweDFSP aluqhelekanga kakhulu.

Yintoni ebangela i-DFSP?

Okumangalisayo kukuba, abantu abali-9 kwabali-10 abafumana i-DFSP banotshintsho lwemfuza olubangela le meko . Olu tshintsho lwemfuza lwenzeka kwiiseli zethu emva kokuba sizelwe. Oku kuthetha ukuba i-DFSP ayibangelwa sisiphene semfuza esizuzwe kubazali bethu.

Ziziphi izinto ezibangela umngcipheko wokuphuhlisa i-DFSP?

Ukongeza kuhlanga, ukuba noluphi na uhlobo lokwenzakala kwesikhumba okanye amanxeba kunokunyusa umngcipheko wokuba ne-DFSP. Kukho iindlela ezahlukeneyo zokwenzakala kwesikhumba:

• Ukutsha
• Ufumana unyango lwemitha
• Ukusikwa ngotyando
• Iitattoos

Khawucinge nje, wakha watsha kakhulu kwaye waba nesilonda esikhulu. Okanye, wakha wafumana unyango lwe-radiation lwesinye isifo. Xa ulusu lonakaliswe zizinto ezinje, kukho ithuba elincinci lokuba imeko efana ne-DFSP ivele kwixesha elizayo, nangona kunqabile. Yiyo loo nto kufuneka sihlale siqaphela utshintsho eluswini.

Zithini iimpawu ze-DFSP?

Iimpawu zokuqala ze-DFSP azibonakali kangako kangangokuba sisenokungaziboni okanye sizibone. Ezi thumba zihlala zikhula esifubeni, emqolo, emagxeni, esiswini, okanye ezimpundu. Zinokuvela nakwiingalo, emilenzeni, entlokweni, nangaphakathi emlonyeni.

Ekuqaleni, ungabona indawo encinci efana nokudumba eluswini.Ithe tyaba kwaye ayibuhlungu. Isenokuvakala ngathi irhabaxa xa uyichukumisa, kwaye umbala ungatshintsha kancinci.

Kwiintsana nabantwana abancinci, i-DFSP inokubonakala ngathi luphawu lokuzalwa . La mabala adla ngokuba malunga nesiqingatha sesentimitha ukuya kwiisentimitha ezimbini (1 ukuya kwiisentimitha ezi-5) ububanzi.

Iimpawu ze-DFSP ziyabonakala njengoko umhlaza ukhula. Njengoko ithumba likhula, lityhala liye kumaleko ophezulu wolusu (i-epidermis). Oku kubangela ukuba kuvele amaqhuma aqinileyo (ii-nodules) kumphezulu wolusu . Igama elithi "protuberance" lithetha "ukuvela."

Ungazibona ezi mpawu kwezi ziqhuma:

• Ingaqhekeka okanye yophe igazi lula.
• Inamathele ngokuqinileyo eluswini (ayinakushukunyiswa).
• Njengoko ukhula, ulusu lwakho luyanwebeka.
• Ivakala inzima xa uyichukumisa, okanye ngathi yirabha.
• Umbala ungaba bomvu-mdaka, mfusa, luhlaza okwesibhakabhaka, okanye bomvu.
• Isenokuba thambile kancinci xa ichukunyiswa.

Ngaba kukho ezinye iimeko ezibangela iimpawu ezifana neze-DFSP?

Ewe, kukho imeko yesikhumba engeyoyomhlaza ebizwa ngokuba yi- cellular dermatofibroma . Oku kunokufana kakhulu ne-DFSP, ingakumbi kumanqanaba ayo okuqala. I-Cellular dermatofibromas zii-tumor zezicubu ezithambileyo ezingenabungozi. Zihlala zivela emilenzeni. Ngamanye amaxesha zinokurhawuzelela kwaye zibe buhlungu. Uninzi lwe-dermatofibromas aludingi unyango. Nangona kunjalo, kububulumko ukungazidibanisi zombini ezi zinto, ngoko ke bubulumko ukubona ugqirha ukuba ubona nantoni na entsha eluswini lwakho.

Ifunyanwa njani i-DFSP (i-Dermatofibrosarcoma Protuberans)?

I-DFSP ixilongwa ngoogqirha besikhumba , abangoogqirha abaqeqeshwe ngokukodwa kumhlaza wolusu kunye nezifo zolusu. Ugqirha wakho uza kuqala athathe isampuli encinci yeqhuma okanye ibala lesikhumba aze alithumele kwilebhu ukuze livavanywe (i-skin biopsy) . Iqhuma lonke linokususwa lize lithunyelwe kwilebhu. Iingcali zezifo ziya kujonga izicubu phantsi kwe-microscope ukuze zibone ukuba zinazo na iiseli zomhlaza.

Ukuba i-biopsy yesikhumba iqinisekisa ukuba une-DFSP, ungacelwa ukuba wenze i-MRI scan . Oku kuya kunceda ekuqinisekiseni ubungakanani obuchanekileyo bethumba kunye nokuba lisasazeke kangakanani eluswini. Olu lwazi lubaluleke kakhulu ekucwangciseni unyango.

Ziziphi iindlela zonyango ze-DFSP (Dermatofibrosarcoma Protuberans)?

Olona nyango luphambili nolungcono lwe-DFSP kukususa ithumba ngotyando. Iingcali zesikhumba zihlala zisebenzisa inkqubo ekhethekileyo ebizwa ngokuba yi-Mohs surgery ukususa ithumba le-DFSP. Nantsi into eyenzekayo ngeli xesha lotyando:

• Okokuqala, kufakwa i-anesthetic yendawo kwindawo yonyango, ukuze ungeva ntlungu.
• Emva koko, ugqirha uyasinqumla aze asisuse ithumba elinomhlaza. Kodwa kungekuphela nje ithumba, kodwa nendawo encinci yolusu olusempilweni olujikelezileyo. Oku kubizwa ngokuba yi-margin .
• Okulandelayo, imiphetho (imida) yezicubu ezisusiweyo ihlolwa phantsi kwemakroskopu ukuze kubonwe ukuba kukho iiseli zomhlaza eziseleyo na.
• Ukuba kusekho iiseli zomhlaza emaphethelweni, ugqirha uza kususa ezinye izicwili kwindawo apho utyando lwenziwe khona kwakhona.
• Ngale ndlela, ukususwa kwezicubu kuyaqhubeka de kungabikho ziseli zomhlaza ezifumanekayo emaphethelweni.
• Emva kokuba umhlaza ususiwe ngokupheleleyo, kwenziwa utyando lokwakha kwakhona ukuba kuyimfuneko.

Ngaba kukho ezinye iindlela zonyango ze-DFSP ngaphandle kotyando?

Nokuba iithumba zeDFSP zisusiwe ngotyando, ngamanye amaxesha zinokubuya. Emva kokususwa okuqhelekileyo okubanzi, kukho ithuba eliyi-20% ukuya kwi-30% lokuba ziya kuphinda zibuye kwiminyaka emithathu. Emva kotyando lweMohs, le ngozi yehla iye kwi-4% ukuya kwi-5%. Nangona kunjalo, kubalulekile ukuhlala ulumkile, njengoko iithumba zinokuphinda zibuye nokuba emva kweminyaka eli-10 nangaphezulu.

Ngamanye amaxesha, ukuba umhlaza usasazeke kwamanye amalungu omzimba (i-metastatic DFSP), okanye ukuba ithumba likhulu kakhulu okanye likwindawo ethile ukuba lingasuswa ngotyando, oogqirha basebenzisa iyeza elibizwa ngokuba yi-Imatinib . Eli yeza linokucutha ithumba, okwenza kube lula ukulisusa ngotyando.

Kwakhona, ukuba utyando alunakuwususa ngokupheleleyo umhlaza, okanye ukuba utyando alunakwenzeka kwaphela, unyango lwemitha lungasetyenziswa.

Injani imbono yomntu one-DFSP?

Ezi ziindaba ezithuthuzelayo ngokwenene. Ekubeni i-DFSP ingumhlaza okhula kancinci, ongasebenzi kakuhle, xa unyango lufanelekile, abantu abangaphezu kwama-99% baya kuphila iminyaka eli-10 nangaphezulu. Ngoko ke, eyona nto ibalulekileyo kukungaxhalabi uze ulandele icebiso likagqirha wakho.

Yintoni endinokuyenza ukuphucula indlela endizibona ngayo izinto?

Kukho izinto ezininzi onokuzenza ukuze uphucule indlela ocinga ngayo:

• Zihlole rhoqo ulusu lwakho. Khangela naluphi na utshintsho olutsha, amabala, okanye amaqhuma eluswini lwakho. Ukuba ubona nantoni na, xelela ugqirha wakho ngoko nangoko.
• Emva konyango, bona ugqirha wakho ukuze ahlolwe ulusu ubuncinane rhoqo kwiinyanga ezintathu ukuya kwezintandathu kwiminyaka emithathu yokuqala. Emva koko yiya kuhlolwa kube kanye ngonyaka, okanye njengoko ugqirha wakho eyalele.
• Nciphisa ukuvezwa lilanga. Imitha ye-UV evela elangeni inyusa umngcipheko weminye imihlaza yolusu. Ngoko ke, nxiba i-sunscreen xa uphuma elangeni, nxiba impahla yokuzikhusela , kwaye unciphise ixesha lakho ngaphandle ngexesha elishushu kakhulu emini.

Ndifanele ndimbone nini ugqirha?

Ukuba ubona naluphi na utshintsho olutsha eluswini lwakho, ingakumbi ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba ubona ugqirha:

• Amaqhuma okanye amabala amatsha, ahlala ekho, okanye ukukhula kolusu olutsha.
• Utshintsho kwiintsumpa, ii-birthmarks, amanxeba amadala, okanye ii-tattoos.
• Ukuba amaqhuma eluswini opha ngokulula.

Khumbula, utshintsho lolusu ludla ngokuba yingozi. Nangona kunjalo, ezinye iinguqulelo zinokuba luphawu lomhlaza wolusu. Ngoko ke, ukuba unamathandabuzo, kungcono ukubona ugqirha ukuze alungise ingxaki.

Ndimele ndibuze ntoni kugqirha wam?

Ukuba ufunyaniswe une-DFSP, ungabuza ugqirha wakho imibuzo efana nale:

• Kutheni ndifumene lo mhlaza wolusu?
• Ngaba ndisengozini yokufumana ezinye iintlobo zomhlaza wolusu?
• Yeyiphi indlela engcono yonyango kum?
• Ingaba kukho umngcipheko wokuba lo mhlaza usasazeke nakwamanye amalungu omzimba?
• Ndifanele ndiye kangaphi ukuze ndihlolwe umhlaza?

Ukwazi iimpendulo zale mibuzo kuya kukunceda uqonde ngcono imeko kwaye kunokukunceda ucacise unyango lwakho kunye nezicwangciso zakho zexesha elizayo.

Okokugqibela, izinto ekufuneka uzikhumbule

Nangona i-DFSP ingumhlaza wolusu ongaqhelekanga, akunakwenzeka ukuba isasazeke kwezinye iindawo zomzimba. Nangona kunjalo, unyango lotyando lubalulekile ukuze kumiswe ukukhula. Ukufunyanwa kwangoko kunye nonyango olufanelekileyo kunokuphucula kakhulu indlela ojonga ngayo izinto. Ngoko ke, lumka ulusu lwakho kwaye ubone ugqirha ukuba ubona nantoni na engaqhelekanga. Awuwedwa, kwaye kukho oogqirha abanokukunceda kolu hambo.

I- DFSP, umhlaza wolusu, umhlaza wolusu, amaqhuma olusu, utyando lwe-Mohs, iimpawu zomhlaza, izifo zolusu