Ngaba uyazi nge-'happy hormone' i-Dopamine? Masixoxe ngayo ngokweenkcukacha - Nirogi Lanka

Ngaba wakha weva nge "hormone yokuziva kamnandi"? Ngaba uyayazi loo mvakalelo xa uziva wonwabile ngequbuliso, ukhuthazekile, okanye uchulumancile? Oko kunxulunyaniswa kakhulu nento ebizwa ngokuba yi-dopamine. Idlala indima ebalulekileyo kwimisebenzi emininzi ebalulekileyo yomzimba wakho. Ngoko ke, masingene ngaphakathi size sifunde ukuba yintoni kanye kanye i-dopamine kwiNirogi Lanka.

Yintoni kanye kanye iDopamine?

Ngamafutshane, i-dopamine sisithunywa seekhemikhali sendalo esiveliswa engqondweni yakho. Sikwiqela leekhompawundi ezibizwa ngokuba yi -monoamine neurotransmitters.Cinga ngeeseli zemithambo-luvo zobuchopho bakho njengezihlala zithetha; i-dopamine isebenza njenge "chemical courier" enceda ekudluliseni le miyalezo kwiindawo eziphakathi kweeseli. Idlala indima ebalulekileyo ekudluliseleni le miqondiso isuka engqondweni yakho iye emzimbeni wakho wonke.

I-Dopamine ikwasebenza njengehomoni . Kunye ne-epinephrine kunye ne-norepinephrine, ihlelwa njenge- catecholamine . Ezi homoni ziveliswa ikakhulu zii -adrenal glands zakho, ezihlala njengee-caps ezincinci phezu kwezintso zakho. Ukongeza, i-hypothalamus yengqondo yakho ikhupha i-dopamine njenge- neurohormone .

Yintoni eyenziwa yi-dopamine emzimbeni wakho? Apha eNirogi Lanka, sikunceda uqonde indima yayo ebalulekileyo.

I-Dopamine ibandakanyeka kwimisebenzi emininzi ebalulekileyo yomzimba. Makhe sijonge ngokusondeleyo ukuba isebenza njani.

I-Dopamine njenge-Neurotransmitter

Njenge-neurotransmitter, i-dopamine inegalelo kwezi zinto zilandelayo:

• Intshukumo: Inceda ukulungelelanisa nokulawula iintshukumo zomzimba wakho.
• Inkumbulo: Kubalulekile ekufundeni nasekugcineni ulwazi.
• Umvuzo Omnandi Nokukhuthaza: Xa uziva wonwabile ngumsebenzi othile, i-dopamine iyawuqinisa loo mkhwa, ikwenze ufune ukuwuphinda.
• Ukuziphatha kunye nokuqonda: Kuchaphazela indlela ocubungula ngayo ulwazi kwaye kubumba iipatheni zakho zokuziphatha.
• Ingqalelo: Ikunceda ugxile kwaye ugcine ingqondo yakho igxile.
• Ukulala Nokuvuka: Kudlala indima ebalulekileyo ekulawuleni imijikelo yakho yokulala nokuvuka.
• Imo Yengqondo: Ichaphazela kakhulu imeko yakho yeemvakalelo, ichaphazela iimvakalelo zolonwabo okanye zosizi.
• Ukufunda: Kubalulekile ekufumaneni izakhono nolwazi olutsha.
• Ukuncancisa: Kunceda ekulawuleni iinkqubo zehomoni ezibandakanyeka ekuncanciseni.

I-Dopamine njengeHormone

Xa isebenza njengehomoni, i-dopamine ingena egazini lakho. Inegalelo kwimpendulo yomzimba wakho "yokulwa okanye ukubaleka" ngexesha leemeko ezixinzelelekileyo. Ngokwenyani, ukuba udibana nosongelo olukhawulezileyo, i-dopamine inceda ekulawuleni indlela umzimba wakho osabela ngayo ngokwasemzimbeni kolo xinzelelo.

Ngaphezu koko, njengehomoni, i-dopamine yenza eminye imisebenzi ebalulekileyo:

• Inceda ukwandisa imithambo yegazi (kwiidosi eziphantsi) okanye ukuyinciphisa (kwiidosi eziphezulu).
• Ikhuthaza izintso zakho ukuba zikhuphe i-sodium (ityuwa) kunye nomchamo omninzi.
• Iyanciphisa ukuveliswa kwe-insulin kwi -pancreas yakho.
• Iyanciphisa isantya sokuhamba kokutya kwindlela yesisu (GI) , inceda ekukhuseleni ulwelo lwangaphakathi.
• Iyanciphisa umsebenzi wee-lymphocytes kwinkqubo yakho yokuzikhusela.

I-dopamine ikwenza njani uzive ulungile?

I-Dopamine idla ngokubizwa ngokuba yi-"hormone yokuziva kamnandi" kuba ivuselela iimvakalelo zolonwabo nolwaneliseko. Ikwakhuthaza inkuthazo yakho, ikukhuthaze ukuba uphinde iindlela zokuziphatha eziye zaphumela kumvuzo omhle.

Cinga nge-dopamine njengenxalenye ebalulekileyo "yenkqubo yomvuzo" yengqondo yakho. Le nkqubo yaphuhliswa ukuze inike ulwaneliseko olukhulu xa usenza izenzo ezifunekayo ukuze usinde—njengokutya, ukuhlala unamanzi emzimbeni, okanye ukusukela usukelo. Ingqondo yakho idityaniswe nokufuna imisebenzi ebangela ukukhululwa kwe-dopamine. Xa ubandakanyeka kwinto eyonwabisayo, ingqondo yakho ikhupha i-dopamine eninzi, ekwenza uzive ulungile kwaye ikukhuthaze ukuba ufune loo mava kwakhona.

Yiyo kanye le nto ezinye ukutya, ingakumbi "ukutya okungenamsebenzi" okucutshungulwe kakhulu kunye neziphuzo ezineswekile, kunokuba ngumlutha kangaka. Ukuzitya kubangela ukukhululwa okukhulu kwe-dopamine engqondweni yakho, okudala "ukutya okunesondlo" okwethutyana oziva unyanzelekile ukuba ukuphinde.

Injani inqanaba le-dopamine elilinganayo?

Xa amanqanaba akho e-dopamine elungelelene kwaye elungile, unokuziva:

• Ngokubanzi wonwabile kwaye wanelisekile.
• Ukhuthazwe kwaye uqhutywa.
• Isilumkiso kwaye ubandakanyekile.
• Ugxile kwaye uyakwazi ukugxila ngokufanelekileyo.

Kuthekani ukuba amanqanaba e-dopamine aphantsi?

Amanqanaba aphantsi e-dopamine anokubangela ukuba ufumane amava alandelayo:

• Ukudinwa rhoqo okanye amandla aphantsi.
• Ukungabikho kwenkuthazo okanye umdla.
• Iimvakalelo ezingapheliyo zokungonwabi okanye ukungakhathali.

Ukongeza, ungabona:

• Ubunzima ngenkumbulo.
• Ukuhamba kweemvakalelo.
• Ukuphazamiseka kokulala.
• Ukungakwazi ukugxila.
• Ukunciphisa inkanuko yobulili.

Kuthekani ukuba amanqanaba e-dopamine aphezulu kakhulu?

Amanqanaba aphezulu kakhulu e-dopamine anokubangela iimvakalelo ezifana nezi:

• Uvuyo olukhulu okanye ukuvuya kakhulu.
• Ukusebenza ngokugqithisileyo okanye amandla agqithisileyo.
• Ukukhulisa inkanuko yobulili.

Nangona kunjalo, amanqanaba aphezulu e-dopamine anokubangela iingxaki ezinkulu. Ukuba uziva uneempawu ezingathandekiyo, nceda ufumane unyango lobuchwephesha kwisibhedlele esikufutshane nawe okanye utsalele umnxeba ku-911 ukuba yingxaki.

• Ubunzima bokulala okanye ukulala.
• Ukulawula iminqweno engafanelekanga, okukhokelela ekwenzeni izigqibo ngokungxama okanye ngequbuliso.
• Ukwanda kobundlongondlongo.

Ziziphi iimeko zempilo ezinxulumene namanqanaba e-dopamine angalinganiyo?

Iimeko ezininzi zempilo zinxulunyaniswa namanqanaba e-dopamine aphezulu kakhulu okanye aphantsi kakhulu. Nangona kunjalo, isayensi isatshintsha kule ndawo. Akucaci nokuba ukungalingani kwe-dopamine kubangela imeko, okanye ukuba imeko engaphantsi kwayo ibangela ukungalingani—kwaye rhoqo, yindibaniselwano yazo zombini. Ngaphezu koko, ingqondo yakho yinkqubo entsonkothileyo; i-dopamine ayisebenzi yodwa. Isebenza ngokuvumelana nezinye ii-neurotransmitters ezahlukeneyo, ii-hormones, kunye neekhemikhali, nto leyo eyenza olu nxibelelwano lube nzima kakhulu.

Nangona kunjalo, nazi iimeko ezininzi ezinxulumene nokungalingani kwe-dopamine:

Iimeko ezinxulumene ne-dopamine ephantsi:

• Ingxaki Yokungakwazi Ukuqwalasela Izinto Ngokupheleleyo (ADHD): Uphando lubonisa ukuba abantu abane-ADHD badla ngokuba namanqanaba aphantsi e-dopamine.
• Isifo sikaParkinson: Le meko yenzeka xa iiseli ezithile zobuchopho ezivelisa i-dopamine ziqala ukuwohloka.
• I-RLS (Restless Legs Syndrome): Imeko ebonakaliswa ziimvakalelo ezingathandekiyo emilenzeni, nto leyo edala umnqweno ongenakuthintelwa wokuyishukumisa.

Iimeko ezinxulumene ne-dopamine ephezulu:

• I-Mania: Imeko yengqondo ephawulwa kukuchwayita okukhulu, isimo sengqondo esiphezulu, kunye nomsebenzi ophezulu.
• Ukutyeba kakhulu: Izifundo ezininzi zibonise unxibelelwano olunokwenzeka phakathi kokulawulwa kwe-dopamine kunye nokutyeba kakhulu.
• Umlutha: I-Dopamine idlala indima ebalulekileyo kumjikelo wokuxhomekeka kwizinto ezibangela umlutha kunye nokuziphatha okufana nokungcakaza.

Iimeko ezinxulumene ne-dopamine ephantsi nephezulu:

• I-Schizophrenia: Le yimeko enzima yempilo yengqondo. Iimpawu ezithile, ezinje ngokubona izinto ezingekhoyo okanye ukuphupha izinto ezingaqhelekanga, zinokunxulunyaniswa ne-dopamine engaphezulu kwiindawo ezithile zobuchopho, ngelixa ezinye iimpawu, ezinje ngokungabikho kwenkuthazo okanye ukurhoxa eluntwini, zinokunxulunyaniswa namanqanaba aphantsi e-dopamine kwiindawo ezahlukeneyo.

Ngawaphi amayeza anxulumene ne-dopamine?

Kukho amayeza ahlukeneyo enzelwe ukulawula amanqanaba e-dopamine okanye ukulinganisa umsebenzi wayo. Masiwahlolisise phantsi kwesikhokelo sikaNirogi Lanka.

Zithini iiDopamine Agonists?

Ii-dopamine agonists zisebenza njenge-dopamine yendalo yomzimba wakho. Zibopha kwaye zivuselele ii-dopamine receptors engqondweni, zibangela impendulo efana naxa i-dopamine yakho isebenza kwiiseli zemithambo-luvo.

La mayeza asetyenziselwa ukunyanga izifo ezifana nesifo sikaParkinson, ukudakumba, i-Restless Legs Syndrome (RLS), i-ADHD, i-libido ephantsi, kunye ne-hyperprolactinemia (ukuveliswa okugqithisileyo kwehomoni evelisa ubisi).

Imizekelo ibandakanya:

• Kwi-Parkinson's: iPramipexole (Mirapex®), iRopinirole (Requip®), iRotigotine (Neupro®), iApomorphine HCl (KYNMOBI®).
• Kwi-Depression: IPramipexole (Mirapex®).
• Kwi-Libido Ephantsi: IPramipexole (Mirapex®).
• Kwi-Hyperprolactinemia: iBromocriptine (Parlodel®), iCabergoline (Dostinex®).

Zithini iiDopamine Antagonists?

Ii-dopamine antagonists zisebenza ngokuvala ii-dopamine receptors engqondweni, zithintela ngempumelelo i-dopamine ukuba ingafikeleli kwiseli yemithambo-luvo elandelayo. Amayeza amaninzi e-antipsychotic awela kolu didi.

Ezi zisetyenziselwa ukunyanga i-schizophrenia, isifo se-bipolar, kunye neempawu zesicaphucaphu nokuhlanza.

• Kwi-Schizophrenia-agitation: I-Aripiprazole (Abilify®), i-Risperidone (Risperdal®), i-Ziprasidone (Geodon®).
• Kwi-Bipolar Disorder: I-Risperidone, i-Olanzapine (i-Zyprexa®), i-Ziprasidone.
• Xa une-Nausea kunye ne-Garmiting: I-Metoclopramide (Reglan®), i-Droperidol (Inapsine®).

Zithini iiDopamine Reuptake Inhibitors?

Izithinteli zokuphinda kuthathwe i-dopamine zithintela iseli yemithambo-luvo ekhuphe i-dopamine ekubeni iphinde iyifunxe. Oku kushiya i-dopamine engaphezulu engqondweni ukuze isetyenziswe ziiseli zemithambo-luvo ezikufutshane.

La mayeza anceda ekunyangeni ukudakumba kunye ne-narcolepsy (ukozela kakhulu emini), kwaye anokunceda ekuchacheni kwimikhwa efana nokutshaya okanye ukutya kakhulu.

• Kwi-Depression: I-Bupropion (i-Wellbutrin®).
• Kwi-Narcolepsy: I-Modafinil (i-Provigil).
• Kwinkxaso yoKukhotyokiswa: iBupropion, iNomifensine, iBenztropine (Cogentin), iMazindol.
• Ukuyeka ukutshaya: I-Bupropion.

Yintoni iLevodopa?

ILevodopa yeyona iyeza liphambili elisetyenziselwa ukunyanga isifo sikaParkinson. Imingeni yokuhamba kwiParkinson ibangelwa kukulahlekelwa yidopamine. Ukuqinisekisa ukuba iLevodopa ifikelela ebuchotsheni ngokufanelekileyo, idla ngokudityaniswa neCarbidopa. Nje ukuba ingene ebuchotsheni, iguqulwa ibe yidopamine.

Iyintoni indima ye-dopamine kwiziyobisi?

Ukusetyenziswa kweziyobisi zokuzonwabisa kuphazamisa indlela iiseli zakho zengqondo ezithumela kwaye zifumana ngayo imiyalezo. Izinto ezithile ezifana ne-cannabis okanye i-heroin zifana nee-neurotransmitters zendalo. Ezinye, ezifana ne-amphetamines okanye i-cocaine, zibangela ukwanda okukhulu kokukhululwa kwe-dopamine okanye zithintele ukufunxwa kwayo kwakhona. Ukuba wena okanye umntu omaziyo uyasokola, nceda unxibelelane neenkonzo zongxamiseko zasekuhlaleni okanye uye esibhedlele esikufutshane ngoko nangoko.

Ezi zinto zivuselela kakhulu "iziko lembuyekezo" lobuchopho bakho. Xa usebenzisa iziyobisi rhoqo ngokuhamba kwexesha, iindawo ezithile zengqondo yakho ziyaphelelwa luvakalelo, nto leyo eyenza kube nzima ukuziva wonwabile nakweyiphi na enye into. Kwangaxeshanye, ufumanisa ukuba udinga izixa ezikhulu zale nto ukuze ufumane isiphumo esifanayo. Ngaphezu koko, ezinye iindawo zengqondo yakho ziba novakalelo olukhulu kwintlungu-efana nokuxhalaba nokungaphumli-okuvela xa le nto iphela. Oku kukukhokelela ekubeni uphinde uyisebenzise le nto ukuze ubalekele ezo mvakalelo zimbi. Ngokwenyani, umlutha ngumjikelo ombi ophuhliswa ngeendlela ezahlukeneyo ezintsonkothileyo.

Izazinzulu ngoku zikholelwa ukuba indima ye-dopamine ayikokuvelisa nje uvuyo; endaweni yoko, isebenza njengophawu lokuqinisa olunceda ingqondo yakho ikhumbule amava amnandi ukuze uqhutywe ukuwaphinda. Xa iziyobisi zibangela ukwanda okukhulu kwe-dopamine, ingqondo yakho "iyafunda" ngokufanelekileyo ukufaka loo mava. Ingqondo yakho iqala ukudibanisa ukusebenzisa kwakho iziyobisi nayo yonke imikhwa, uphawu lokusingqongileyo, kunye nesiqhelo owawunaso ngelo xesha. Yiyo loo nto kanye, nokuba ucocekile ixesha elide, ukubuyela kwindawo apho wawusebenzisa iziyobisi khona kunokubangela iminqweno enamandla.

Ungawanyusa njani amanqanaba e-dopamine ngokwendalo?

Ungazama ukubandakanya imikhwa enceda ekuxhaseni amanqanaba e-dopamine asempilweni. Nangona kunjalo, nceda uqaphele ukuba uphando oluthe kratya luyadingeka ukuze uqonde ngokupheleleyo indlela ukhetho oluthile lokutya oluchaphazela ngayo ngokuthe ngqo ii-neurotransmitters ezifana ne-dopamine.

• Yitya ukutya okutyebileyo kwi-magnesium kunye ne-tyrosine. Ezi zezona zinto zibalulekileyo zokwakha i-dopamine. I-Tyrosine yi-amino acid efunxwa ngumzimba wakho kwaye iyithuthele engqondweni, apho iguqulwa ibe yi-dopamine. Ukutya okuhlala kukhankanywa ukuxhasa ukuveliswa kwe-dopamine kubandakanya: inkukhu, ii-almond, ii-apile, ii-avokhado, iibhanana, ii-beet, itshokholethi (ingakumbi itshokholethi emnyama), imifuno eluhlaza enamagqabi, iti eluhlaza, iimbotyi zelima, i-oatmeal, ii-orenji, i-okra, imbewu yesesame kunye nethanga, iitumato, i-turmeric, i-watermelon, kunye ne-wheat germ.
• Zibandakanye kwimisebenzi ekwenza uzive wonwabile kwaye ukhululekile. Le misebenzi kukholelwa ukuba ixhasa amanqanaba e-dopamine. Imizekelo ibandakanya: ukuzilolonga rhoqo, ukucamngca, i-yoga, ukufumana imassage, ukudlala nesilwanyana sasekhaya, ukuchitha ixesha kwindalo, okanye ukufunda incwadi elungileyo.

Umyalezo Wokuya Ekhaya

I-Dopamine isebenza njenge-neurotransmitter kunye ne-hormone. Idlala indima ebalulekileyo kwimisebenzi emininzi ebalulekileyo yomzimba wakho, ngakumbi kwintshukumo, inkumbulo, ulonwabo kunye nokukhuthaza. Ukuguquguquka kwamanqanaba e-dopamine kunxulunyaniswa neemeko ezahlukeneyo zempilo yengqondo kunye neengxaki ze-neurological.

I-Dopamine iyinkimbinkimbi kakhulu. Abaphandi basafumanisa indlela esebenzisana ngayo nezinye ii-neurotransmitters, ii-hormones, kunye neekhemikhali engqondweni, kunye nendlela ezi ntsebenziswano ezichaphazela ngayo impilo yakho iyonke.

Ukuba ukrokrela ukuba uneempawu ze-dopamine ephantsi okanye ephezulu, nceda udibane nogqirha wakho. Ugqirha wakho unokuvavanya iimpawu zakho, enze uvavanyo olufunekayo, kwaye anikezele ngesicwangciso sonyango esilungiselelwe wena ukuba kukho imeko yempilo. Khumbula, ungaze uzame ukuzixilonga okanye ukuzenza ngokwakho unyango, ingakumbi malunga nemisebenzi enzima ye-neurological.

Amagama angundoqo: iDopamine, iNeurotransmitter, iHormone, ubuchopho, impilo yengqondo, isifo sikaParkinson, umlutha