Konke malunga nehomoni ye-FSH: Ichaphazela njani inzala yakho? (Ihomoni evuselela i-Follicle - FSH)

Mhlawumbi ukhe waliva igama elithi "iihormone" kakhulu, akunjalo? Ezi hormone zilawula izinto ezininzi emizimbeni yethu, njengeemvakalelo, ukukhula, ukulala, kunye nendlala. Ngoko ke, namhlanje siza kuthetha ngehomoni ekhethekileyo ebaluleke kakhulu kuphuhliso lwesondo kunye nokukwazi ukuba nabantwana, oko kukuthi, ukuzala. Elo homoni yi-FSH, okanye iHormone evuselela iFollicle. Nangona igama lisenokubonakala linzima kancinci, umsebenzi walo kulula kakhulu ukuwuqonda.

Ngamafutshane, yintoni i-FSH?

I-FSH yihomoni eveliswa yi-pituitary gland, i-gland encinci engqondweni yethu. Umsebenzi wayo ophambili kukulawula ukusebenza kwama-ovari kubasetyhini kunye nama-testicles kumadoda.

Xa usiva eli gama, abanye banokucinga ukuba oku kunxulumene neefollicle zeenwele. Kodwa akunjalo. Elinye iqela leehomoni ezibizwa ngokuba yi-androgens lichaphazela ukukhula kweenwele. I-FSH ifumene igama layo kuba ivuselela iingxowa ezincinci ezizaliswe lulwelo ezibizwa ngokuba ziifollicle ze-ovarian kwii-ovari zabasetyhini. Ezi follicle ziqulathe amaqanda.

Zithini imisebenzi yehomoni ye-FSH?

I-hormone ye-FSH ibalulekile ngeendlela ezahlukeneyo kumanqanaba ahlukeneyo obomi bethu. Makhe sibone ukuba njani.

Ukukhulisa umntwana esibelekweni

Okumangalisayo kukuba, ngexesha leetrimester zesibini nezesithathu zokukhulelwa, ukususela kwiiveki ezili-13 ukuya ekuzalweni, i-pituitary gland yomntwana iqala ukuvelisa iihomoni ezibizwa ngokuba yi-FSH kunye ne-LH (i-Luteinizing Hormone). La manqanaba ehomoni afikelela kwinqanaba eliphakathi lokukhulelwa, njengoko i-ovarian follicle yokuqala okanye i-seminiferous tubule yomntwana ikhula.

Ngexesha lokufikisa

Ngexesha lobuntwana, amanqanaba e-FSH adla ngokuba phantsi kakhulu. Nangona kunjalo, njengoko ixesha lokufikisa lisondela, ngokuqhelekileyo phakathi kweminyaka eli-10 neli-14, i-hypothalamus esebuchotsheni ivelisa i-hormone ebizwa ngokuba yi-GnRH (i-Gonadotropin-releasing hormone). Le GnRH inika i-pituitary gland uphawu lokuba iqale ukuvelisa i-FSH kunye ne-LH. Kulapho kuqala khona ukuvuthwa ngokwesondo kunye notshintsho oluhambelanayo lomzimba.

• Abafana: I-FSH kunye ne-LH zisebenza kunye ukukhuthaza amasende ukuba avelise i-testosterone . Le hormone inoxanduva lotshintsho kumakhwenkwe ngexesha lokufikisa, njengokukhula kweenwele emzimbeni, ukujula kwelizwi, kunye nokuveliswa kwesidoda.
• Kumantombazana: I-FSH kunye ne-LH zisebenza kunye ukukhuthaza ama-ovari ukuba avelise i-hormone i-estrogen . Le hormone inoxanduva lokukhula kwamabele kunye nokuqala kokuya exesheni .

Abafazi abasexesheni

Umsebenzi oyintloko wehomoni ye-FSH kukulawula umjikelo wokuya exesheni kowesifazane osexesheni. Ngamafutshane, i-FSH ivuselela ukukhula kwee-follicles kuma-ovari, ilungiselela amaqanda ukuze alungele ukukhutshwa kweqanda. Njengoko ezi follicles zikhula, zikhupha i-estrogen kunye ne-progesterone encinci egazini.

Phakathi kweentsuku zesi-6 nese-14 zomjikelo wokuya esikhathini, i-FSH ibangela ukuba ii-follicles ezininzi kwi-ovary ziqale ukuvuthwa. Kodwa kwiintsuku ze-10-14, i-follicle enye kuphela kwezi ikhule yaba liqanda elivuthiweyo ngokupheleleyo. Malunga nosuku lwe-14, kukho ukunyuka ngequbuliso kwe-hormone ye-LH. Oku kubangela ukuba i-follicle evuthiweyo ngokupheleleyo iqhume kwaye ikhuphe iqanda. Oku sikubiza ngokuba yi-ovulation .

Emva kokukhutshwa kweqanda, i-follicle eqhekekileyo iba yi-gland yexeshana ebizwa ngokuba yi-corpus luteum, evelisa inani elikhulu le-hormone progesterone. Le progesterone iyayimisa imveliso ye-FSH kwaye ilungiselela udonga lwesibeleko ukukhulelwa.

Zamadoda

Umsebenzi ophambili wehomoni yamadoda i-FSH kukukhuthaza ukuveliswa kwesidoda . I-FSH ikwanceda ukugcina ukuveliswa kwesidoda ngokusebenzisana ne-testosterone, eveliswa yi-LH.

Ilawulwa njani imveliso ye-FSH?

Le yinkqubo yokulawula entsonkothileyo. Ifana nendlela esebenza ngayo inkampani enkulu. Siyibiza ngokuba yi-hypothalamic-pituitary-gonadal axis. Iindawo zobuchopho (i-hypothalamus, i-pituitary gland) kunye ne-gonads (amaqanda/amasende) kule nkqubo zihlala zinxibelelana.

1. Isiqalo: Okokuqala, i-hypothalamus ivelisa i-hormone ebizwa ngokuba yi-GnRH.

2. Ukukhuthaza: Le GnRH iya kwi-pituitary gland ize iyixelele ukuba ivelise iihomoni ze-FSH kunye ne-LH.

3. Isenzo: I-FSH kunye ne-LH, eziveliswa yi-pituitary gland, zihamba ngegazi zize zibopheleleke kwii -ovari okanye kuma-testicles (gonads) ukulawula ukusebenza kwazo.

4. Ingxelo: Emva koko, iihomoni eziveliswa zii-ovari kunye nama-testicles (ezifana ne-estrogen kunye ne-testosterone) zithumela imiqondiso engqondweni ukuze ziyixelele ukuba ingakanani i-GnRH, i-FSH, kunye ne-LH ekufuneka ivelise. Oku kuyaqhubeka kumjikelo.

Ukuba kukho ukungasebenzi kakuhle okuncinci naphi na kule nkqubo, ibhalansi yonke yehomoni inokuphazamiseka.

Anjani amanqanaba aqhelekileyo e-FSH?

Amanqanaba aqhelekileyo e-FSH ayahluka ngokuxhomekeke kubudala, isini, kunye nosuku lomjikelo wokuya esikhathini kwabasetyhini. Okubalulekileyo kukuba, uluhlu oluqhelekileyo lunokwahluka kancinci phakathi kweelebhu. Ke ngoko, kubalulekile ukuthelekisa iziphumo zakho noluhlu oluqhelekileyo lwelebhu kwingxelo yakho. Ukuba unemibuzo malunga neziphumo zakho, qiniseka ukuba uthetha nogqirha wakho.

Apha ngezantsi kukho amaxabiso amkelekileyo ngokubanzi. Iyunithi yokulinganisa yi-mIU/mL (iiyunithi ze-milli-international nge-milliliter).

Ngaba kukho inqanaba elifanelekileyo le-FSH lokukhulelwa?

Lo ngumbuzo obaluleke kakhulu kwizibini ezinethemba lokuba nabantwana. Ukulinganisa amanqanaba e-FSH kubalulekile xa kuvavanywa ukuba ukhulelwe na. Ixesha elifanelekileyo lokwenza olu vavanyo lusuku lwesi-3 lomjikelo wokuya exesheni (usuku lokuqala lokuya exesheni luthathwa njengosuku loku-1).

Uphononongo lweziphumo zonyango lwe-IVF (In Vitro Fertilization) lubonise ukuba abo banamanqanaba e-FSH angaphantsi kwe-15 mIU/mL ngosuku lwesi-3 babenethuba eliphezulu lokukhulelwa kunabo banamanqanaba e-FSH aphakathi kwe-15 kunye ne-24.9. Abo banamanqanaba e-FSH angaphezu kwama-25 babenethuba eliphantsi lokukhulelwa.

Kuthetha ukuthini ukuba nenqanaba eliphezulu le-FSH?

Kwiimeko ezininzi, ukuba amanqanaba e-FSH aphezulu kunesiqhelo, oko kuthetha ukuba kukho ingxaki ngama-ovari okanye amasende .

Khawuthelekelele ukuba ama-ovari okanye ama-testicles awenzi i-estrogen okanye i-testosterone eyaneleyo. Emva koko, i-pituitary gland esebuchotsheni iyakuqonda oku ize icinge, "Kulungile, kufuneka ndithumele i-FSH engaphezulu ukuze ezi zinto zisebenze," kwaye ikhupha i-FSH eninzi egazini. Kodwa ngenxa yengxaki ngee-gonads, azikwazi ukuphendula ngokufanelekileyo kubungakanani be-FSH obungenayo. Le meko siyibiza ngokuba yi-primary hypogonadism . Oku kulandelayo kunokubangela oku:

• Iziphene zokuzalwa:
• Isifo seKlinefelter kumadoda
• I-Turner syndrome kubasetyhini
• Izizathu ezilandelayo:
• I-radiation okanye i-chemotherapy yomhlaza
• Ukulimala kwamaqanda okanye amasende
• Ukwehla kwamanqanaba e-hormone ngokuguga
• Ezinye iimeko zokuzikhusela komzimba
• Izifo ezifana ne-mumps

Kwakhona, ukuyeka ukuya exesheniAmanqanaba e-FSH kwabasetyhini ayanda ngokwemvelo xa bekhupha amaqanda. Oku kuqhelekile. Ukuba amanqanaba e-FSH kubantwana aphezulu kuneminyaka yabo kwaye iimpawu zesondo ziyakhula, oko kusenokuba luphawu lokufikisa kwangethuba .

Kuthetha ukuthini ukuba nenqanaba eliphantsi le-FSH?

Ukuba amanqanaba e-FSH aphantsi kunesiqhelo, oko kudla ngokubonisa ingxaki kwi-pituitary gland okanye kwi-hypothalamus . Ngenxa yokuba ingqondo ayibonisi ukuveliswa kwe-FSH, ama-ovari okanye amasende awasebenzi kakuhle. Le meko ibizwa ngokuba yi -hypogonadotropic-hypogonadism .

Oku kusenokuba kungenxa yezi zinto zilandelayo:

• Iingxaki ze-pituitary gland: Izinto ezifana ne-pituitary adenomas zinokubangela ukuba i-gland icinezelwe okanye yonakale, nto leyo enokuphazamisa ukuveliswa kweehomoni.
• Iingxaki zeHypothalamic: Iimeko ezingaqhelekanga zemfuza ezifana neKallmann syndrome zinokubangela ukwehla kwemveliso yehomoni iGnRH, nto leyo enokubangela ukwehla kwamanqanaba e-FSH.

Ziziphi iimpawu zamanqanaba e-FSH angaqhelekanga?

Nokuba amanqanaba e-FSH aphantsi okanye aphezulu, iimpawu zihlala zifana nezo ze -hypogonadism , oko kukuthi, ii-gonads ezingasebenzi kakuhle. Ezi mpawu ziyahluka ngokweminyaka kunye nesini.

Amanqanaba e-FSH alinganiswa njani?

Inqanaba lakho le-FSH linokulinganiswa ngovavanyo lwegazi olulula . Kunye nolu vavanyo, ugqirha wakho unokucebisa ezinye iimvavanyo ezininzi zehomoni ukuze afumane umfanekiso opheleleyo wemeko yakho.

• I-hormone ye-Luteinizing (LH)
• I-Testosterone
• I-Estradiol kunye/okanye i-progesterone

Olu vavanyo ludla ngokwenziwa:

• Ukufumana unobangela wokungabi nabantwana
• Ukuchonga iingxaki ngama-ovari okanye amasende
• Ukuchonga iingxaki nge-pituitary gland okanye i-hypothalamus
• Ukufumana izizathu zokuya exesheni ngendlela engaqhelekanga
• Ukwazi ukuba i-menopause isondela na
• Ukufumana izizathu zokubala isidoda esiphantsi
• Ukufumanisa izizathu zokuba kutheni ukufikisa kwabantwana kulibaziseka okanye kwangethuba.

Ndifanele ndimbone nini ugqirha?

Ukuba wena okanye umntwana wakho unenye okanye ngaphezulu kwezi meko zilandelayo, kubaluleke kakhulu ukubona ugqirha ukuze akunike ingcebiso.

• Ukuba uneempawu ze-hypogonadism ezikhankanywe apha ngasentla (ezifana nokuncipha komnqweno wesondo, ukudinwa kakhulu, ukungazali).
• Ukuba umntwana wakho ungena ebuntwini ngaphambi okanye emva kwexesha eliqhelekileyo .
• Ukuba ukhulelwe umntwana kodwa unengxaki yokukhulelwa .

I-FSH yi-hormone ebalulekileyo ekukhuleni ngokwesondo nasekuzaleni emzimbeni wethu. Ngenxa yokuba idibene ngokunzulu nezinye ii-hormone ezininzi, ngamanye amaxesha amanqanaba ayo anokuba angaqhelekanga. Kodwa ungakhathazeki ngayo. Ukuba ucinga ukuba wena okanye umntwana wakho ninengxaki ngale nto, thetha nogqirha. Bahlala bekulungele ukukunceda.