Xa wena okanye umntu omthandayo nifunyaniswa ukuba ninomhlaza, kuyinto eqhelekileyo ukuba nibe nomdla kakhulu, mhlawumbi nibe novalo, malunga nonyango oluza kunikwa. Ingakumbi xa unikwe iyeza elithile elifana ne-Ivosidenib (Tibsovo), kubaluleke kakhulu ukwazi ukuba liyintoni kanye kanye. Ke namhlanje, masithethe ngeli yeza libizwa ngokuba yi-Ivosidenib, ngokulula kakhulu, ngolwimi onokuluqonda.
Luhlobo luni lonyango i-Ivosidenib?
Ngamafutshane, olu luhlobo "lonyango olujoliswe kulo." Lujolise kwiiproteni ezithile kwiiseli zomhlaza kwaye luzithintele ekukhuleni kwazo. Eli yeza lisetyenziswa kakhulu ukunyanga izifo ezimbini.
1. I-Acute Myelogenous Leukemia (AML): Lo ngumhlaza okhula egazini nasemongweni wethambo.
2. I-Cholangiocarcinoma: Lo ngumhlaza okhula kwinkqubo ye-bile duct yomzimba wethu.
Ugqirha wakho angakunika eli yeza nakwezinye iimeko. Ukuba unemibuzo malunga noku, buza ugqirha wakho.
Ndimele ndimxelele ntoni ugqirha ngaphambi kokuba ndiqalise eli yeza?
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kufuneka umxelele ngokuqinisekileyo ukuba unayo nayiphi na kwezi meko. Olu lwazi lubaluleke kakhulu kukhuseleko lwakho.
- Ukuba unesifo senkqubo yemithambo-luvo esibizwa ngokuba yiGuillain-Barre syndrome .
- Ukuba unembali yesifo sentliziyo okanye ukubetha kwentliziyo okungahambelaniyo.
- Ukuba unesifo sezintso okanye isifo sesibindi.
- Ukuba uxelelwe ukuba amanqanaba akho e-sodium, potassium, okanye magnesium egazini aphantsi.
- Ukuba ukhe waba ne-allergy kwi-ivosidenib okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe okanye uzama ukukhulelwa. (Oku kubaluleke kakhulu)
- Ukuba ungumama oncancisayo.
Indlela yokusebenzisa amayeza ngokuchanekileyo?
Ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza kubalulekile ukuze unyango luphumelele.
- Le yipilisi oyisela ngomlomo. Yisele kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanayo yonke imihla .
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ipilisi. Ginya ipilisi yonke ngamanzi.
- Ungayithatha le nto ngaphambi okanye emva kokutya, kodwa ukuba uziva ukhathazekile sisisu, kungcono ukuyithatha kunye nokutya.
- Khumbula! Musa ukulisebenzisa eli yeza kunye nesidlo esinamafutha amaninzi.
- Enye into ebalulekileyo! Ungaze ulisebenzise eli yeza kunye nejusi yegrapefruit.
- Qhubeka usela amayeza de ugqirha akuxelele ukuba uyeke.
Wenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, ungalibazisi. Tsalela umnxeba iZiko loLwazi lwePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula, kuphela ukuba sele kudlule iiyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo. Ukuba sele kusondele ixesha lokuthatha idosi elandelayo (ngaphantsi kweeyure ezili-12), yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngexesha elinye.
Ukuba uyahlanza emva kokusela ipilisi, musa ukuyisela enye ipilisi. Thatha idosi yakho elandelayo ngexesha elicwangcisiweyo.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
I-Ivosidenib liyeza elinokusebenzisana namanye amayeza, ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu).
| Uhlobo lweziyobisi | Amanqaku kunye nemizekelo |
|---|---|
| Amayeza angafanele asetyenziswe | ICisapride, iDronedarone, iPimozide, iThioridazine |
| Amanye amayeza e-antiviral e-HIV okanye i-Hepatitis | Ezi zinokutshintsha iziphumo ze-Ivosidenib. |
| Amayeza osulelo lwefungus | Umzekelo: iFluconazole, iItraconazole, iKetoconazole |
| Amayeza okubetha kwentliziyo okungaqhelekanga | Umzekelo: i-Amiodarone, iQuinidine, iPropafenone |
| Amayeza okuxhuzula/ ukuxhuzula | Umzekelo: iCarbamazepine, iPhenobarbital, iPhenytoin |
| Iihomoni zabasetyhini kunye neepilisi zokulawula ukuzalwa | Ukusebenza kweepilisi zokulawula ukuzalwa kunokuncipha. |
| I-wort yaseSt. John | Nangona le yimveliso yemifuno, isenokudibana namayeza. |
| Amanye amayeza andisa ixesha le-QT lokubetha kwentliziyo | Oku kunokubangela utshintsho oluyingozi kwisigqi sentliziyo. |
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
- Iziphumo ebezingalindelekanga eziqhelekileyo: Kuqhelekile ukuba nentloko ebuhlungu okanye isiyezi ngelixa usebenzisa eli yeza. Oku kungenxa yokuba unyango lomhlaza lunokuchaphazela zombini iiseli zomhlaza kunye neeseli ezisempilweni. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, xelela ugqirha wakho. Qhubeka usela iyeza de ugqirha wakho akuxelele ukuba uyeke.
- Uvavanyo lwegazi: Ugqirha wakho uza kuyalela uvavanyo lwegazi rhoqo ngelixa usebenzisa eli yeza. Kubalulekile ukuba ungaluyeki.
- Ukukhulelwa kunye nokuzala: Le yingxaki ebaluleke kakhulu.
Kufuneka ukuphephe ukukhulelwa ngelixa usebenzisa eli yeza. Ukuba ungumfazi, uzama ukukhulelwa, okanye ukrokrela ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko. Ukuba uyindoda, kufuneka ukuphephe ukuba nguyise womntwana ngelixa usebenzisa eli yeza. Oku kunokubangela ingozi enkulu kumntwana ongakazalwa.
- Ulawulo lokuzala: Iipilisi zokulawula ukuzala zisenokungasebenzi kakuhle ngelixa usebenzisa la mayeza, ngoko ke qiniseka ukuba uthetha nogqirha wakho malunga nokusebenzisa olunye uhlobo lolawulo lokuzala (umz., iikhondom).
- Ukuncancisa: Kuphephe ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye kangangenyanga emva komthamo wokugqibela.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, i-Ivosidenib inokubangela iziphumo ebezingalindelekanga. Ezinye zincinci, ngelixa ezinye zifuna ingqalelo ekhawulezileyo.
| Uhlu lweziphumo ebezingalindelekanga | |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ukudumba | Ukutyeba ngequbuliso; ukudumba kwamaqatha, iinyawo, izandla; ubunzima bokuphefumla. |
| Utshintsho kwisantya sentliziyo | Ubunzima bokuphefumla, iintlungu zesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukuquleka. |
| Ezinye iimpawu ezinzulu | Umkhuhlane, utshintsho lombono, ubunzima bokuchama, izilonda zomlomo, iintlungu okanye ukungaziva mnandi kwimilenze, ukudinwa kakhulu. |
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza | |
| Iingxaki zenkqubo yokugaya ukutya | Ukuqhinwa, urhudo, isicaphucaphu, ukuhlanza, iintlungu zesisu. |
| Ezinye izinto ezincinci | Ukulahlekelwa ngumdla wokutya, iintlungu zamalungu, iintlungu zemisipha. |
Ugcina njani amayeza akho ekhuselekile?
- Gcina kude nabantwana kunye nezilwanyana zasekhaya.
- Gcina kubushushu begumbi (phakathi kwama-20-25 degrees Celsius).
- Lahla amayeza aphelelwe lixesha. Buza ugqirha wakho ngendlela echanekileyo yokuwalahla. Ungafumana ulwazi malunga neenkqubo zokubuyisela amayeza.
Umyalezo Wokuya Ekhaya
- Ginya ipilisi ye-Ivosidenib yonke, ungayiqhekezi, ungayityumzi, okanye ungayihlafuni. Yithathe ngexesha elifanayo yonke imihla.
- Kuphephe ukuthatha eli yeza kunye nejusi yegrapefruit kunye nokutya okunamafutha ngokupheleleyo.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza. Sebenzisa olunye uhlobo lokuthintela ukukhulelwa.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ufumana iziphumo ebezingalindelekanga ezinzulu ezifana neentlungu zesifuba, ubunzima bokuphefumla, okanye ukudumba.
- Eli yeza lelakho wedwa. Ungaze wabelane ngalo nabanye.
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