Nazi iimpendulo zemibuzo yakho malunga nesi sifo singaqhelekanga esibizwa ngokuba yiParaganglioma!

Ngaba ngamanye amaxesha uziva ngathi ubila kakhulu, intliziyo yakho ibetha ngokukhawuleza, intloko yakho iyabetha ngamandla? Okanye uziva ngathi uxinzelelo lwakho lwegazi lunyuka ngequbuliso ngaphandle kwesizathu? Nangona unokucinga ukuba ezi zizinto nje ezingaqhelekanga, ngamanye amaxesha kunokubakho esinye isizathu emva koku. I-Paraganglioma yenye yeemeko ezingaqhelekanga kodwa ezibalulekileyo ekufuneka ziqwalaselwe.

Ngoko ke, yintoni le paraganglioma?

Ngamafutshane, iiparagangliomas ziithumba ezingaqhelekanga ezenzeka emzimbeni wakho. Zihlala zikhula kufutshane nomthambo we-carotid, umthambo wegazi omkhulu entanyeni yakho, ecaleni kwemithambo-luvo entlokweni nasentanyeni yakho, okanye kwenye indawo emzimbeni wakho. Ezi thumba zenziwe ngohlobo oluthile lweeseli ezibizwa ngokuba ziiseli ze-chromaffin . Ezi seli zivelisa iihomoni ezibizwa ngokuba zii-catecholamines kwaye zizikhuphele egazini lakho.

Ubusazi na ukuba amadlala e-adrenal, akwizintso zethu, avelisa iintlobo ezahlukeneyo zeehomoni? Ezi catecholamines ziihomoni ezilawula imisebenzi emininzi ebalulekileyo emzimbeni wethu. Uyazi ukuba ziyintoni na?

• Isantya sentliziyo yakho.
• Ifuthe legazi.
• Inqanaba leswekile egazini (`iglucose egazini`).
• Indlela umzimba wethu osabela ngayo kuxinzelelo.

Iintlobo eziphambili ze-catecholamines ezibalulekileyo zezi:

• I-Dopamine.
• I-Epinephrine (le yinto esiyibiza ngokuba yi-adrenaline).
• I-Norepinephrine (ekwabizwa ngokuba yi-noradrenaline).

Nangona ii-paragangliomas zingaphuhli kwi-adrenal glands, ezi thumba zenziwa kwizicubu ezikwi-adrenal glands. Ke ngoko, ukongeza kwezi paragangliomas, ii-catecholamine hormones nazo zinokuqokelelana egazini. Kulapho ke iimpawu ezahlukeneyo ziqala ukubonakala khona.

Yintoni umahluko phakathi kweParanglioma kunye nePheochromocytoma?

La magama mabini anokubhida kancinci, akunjalo? I-Paraganglioma kunye ne-pheochromocytoma zombini zii-tumor ezingaqhelekanga ezivela kwiiseli ze-chromaffin ezikhankanyiweyo apha ngasentla. Umahluko omkhulu phakathi kwezi zimbini kukuba zenzeka phi emzimbeni.

Ii-Pheochromocytomas zikhula kumbindi we-adrenal gland yakho, ebizwa ngokuba yi-adrenal medulla. Ii-paragangliomas zikhula ngaphandle kwe-adrenal gland. Zihlala zifumaneka ecaleni kwemithambo yegazi okanye kwimithambo-luvo entanyeni. Yiyo loo nto ii-paragangliomas ngamanye amaxesha zibizwa ngokuba 'zii-extra-adrenal pheochromocytomas'.

Ngaba iParaganglioma ngumhlaza?

Le yingxaki enabantu abaninzi. Ezi thumba, ezibizwa ngokuba yi-paragangliomas , zinokuba ngumhlaza (ezinobungozi) okanye ezingezizo umhlaza (ezingenobungozi).Ngokwenyani, malunga ne-20% yeeparagangliomas zinomhlaza.

Kodwa umceli mngeni apha kukuba ngamanye amaxesha kunzima koogqirha ukuxelela ngokuqinisekileyo ukuba ithumba lingumhlaza okanye akunjalo. Oko kukuthi, nokuba ithumba lisusiwe ngotyando kwaye izicubu zalo zihlolwe phantsi kwe-microscope, ngamanye amaxesha akunakwenzeka ukutsho ngokuqinisekileyo. Ke ngoko, i-paraganglioma idla ngokuthathwa njengomhlaza kwiimeko ezilandelayo:

• Ukuba ithumba lisasazeke kwizicubu ezingqongileyo (oku kubizwa ngokuba yi-'regional spread of paraganglioma').
• Ukuba isasazeke kwizitho ezikude, njengemiphunga okanye amathambo akho (oku kubizwa ngokuba yi-'metastasized').
• Ukuba ibuye emva kokuba inyangiwe kwaye yanyangwa okokuqala (oku kubizwa ngokuba yi-'recurred').

Ukuba ngumhlaza, usasazeka njani?

Ukuba le paraganglioma ngumhlaza, akukho ndlela iqhelekileyo yokulinganisa i-paraganglioma. Endaweni yoko, ichazwa ngolu hlobo lulandelayo:

• I-paraganglioma ekwindawo ethile: Ithumba likwindawo enye kuphela.
• I-paraganglioma yengingqi: Umhlaza usasazeke kwi-lymph nodes okanye kwezinye izicwili kufutshane nalapho waqala khona.
• I-paraganglioma ekhula ngokukhawuleza: Umhlaza usasazeke nakwamanye amalungu omzimba wakho, njengesibindi sakho, imiphunga, amathambo, okanye ii-lymph nodes ezikude. Phakathi kwama-35% nama-50% e-paragangliomas anomhlaza anokusasaza (akhula ngokukhawuleza ngokukhawuleza) ngale ndlela.
• I-paraganglioma ephindaphindayo: Umhlaza ubuyile emva kokuba unyangiwe kwaye unyangiwe. Unokuba kwindawo efanayo naleyo wawuyiyo ngaphambili, okanye unokuba kwenye indawo yomzimba.

Zikhula ngokukhawuleza kangakanani ezi nati?

Ngokwesiqhelo, iiparagangliomas zikhula kancinci kakhulu. Nangona kunjalo, oku kunokwahluka kumntu nomntu. Abanye abantu banokukhula ngokukhawuleza.

Ngubani ochaphazeleka kakhulu yile meko?

Le meko, ebizwa ngokuba yiparaganglioma , inokukhula nakweyiphi na iminyaka. Nangona kunjalo, ixhaphake kakhulu kubantu abaphakathi kweminyaka engama-30 ukuya kwengama-50. Kwakhona, malunga ne-10% yamatyala axelwa ebantwaneni.

Ixhaphake kangakanani iParaganglioma?

Eli lithumba elingaqhelekanga kakhulu. Ngokwezibalo, kuqikelelwa ukuba ngabantu ababini kuphela kwisigidi abafumana iiparagangliomas. Ngoko ke ungacinga ukuba oku kunqabile kangakanani.

Zithini iimpawu zeParaganglioma?

Iimpawu ze-paragangliomas zibangelwa sisisu esikhupha i-adrenaline okanye i-noradrenaline eninzi kakhulu egazini lakho. Nangona kunjalo, ezinye ii-paragangliomas azivelisi le hormone eyongezelelweyo, ngoko ke azibangeli zimpawu (zibizwa ngokuba azinazimpawu).

Iimpawu ezibonakala kakhuluNgaba:

• Ukuqala ngequbuliso koxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu).
• Intloko ebuhlungu.
• Ukubila kakhulu ngaphandle kwesizathu.
• Ukubetha kwentliziyo okukhawulezayo nokungaqhelekanga okuvakala kakhulu kangangokuba intliziyo inokuvakala ibetha.
• Ukuziva ngathi umzimba wakho uyangcangcazela.

Ukongeza kwezi, kukwakho neempawu ezingaqhelekanga :

• Ukuba mthubi kakhulu kunokuba uqhele ukubonakala.
• Isicaphucaphu kunye/okanye ukuhlanza.
• Urhudo.
• Ukuqhinwa.
• Amanqanaba aphezulu eswekile egazini (i-hyperglycemia).
• Ukwehla ngequbuliso koxinzelelo lwegazi okubangela isiyezi xa usukuma (oku kubizwa ngokuba yi-orthostatic hypotension).
• Ukuba mncane ngaphandle kwesizathu.

Abanye abantu basenokuzibona ezi mpawu rhoqo, okanye ngokugqabhuka. Khawucinge nje, ngamanye amaxesha akukho nto ingalunganga, emva koko ezi mpawu zivele ngequbuliso, zize zinyamalale emva kwexesha elithile. Yiyo loo nto ngamanye amaxesha kungade kube kudala ukuyiqonda le nto.

Yintoni ebangela i-paraganglioma?

Uninzi lwexesha, akukho sizathu sithile se-paragangliomas. Oko kukuthi, zenzeka ngengozi. Nangona kunjalo, malunga ne-25% ukuya kwi-35% yabantu bahlakulela i-paragangliomas ngenxa yemeko yemfuza eyenzeka kwiintsapho (imeko yelifa). Ezinye zezi meko ziquka:

• I-Multiple endocrine neoplasia 2 syndrome, iintlobo A kunye no-B (MEN2A kunye neMEN2B)).
• Isifo seVon Hippel-Lindau (VHL).
• Uhlobo lwe-Neurofibromatosis 1 (NF1).
• I-Hereditary paraganglioma syndrome.
• I-Carney-Stratakis dyad (apho i-paraganglioma inokuhamba kunye ne-gastrointestinal stromal tumor (GIST)).
• I-Carney triad (enokuquka i-paraganglioma, i-GIST, kunye nohlobo lwethumba lemiphunga elibizwa ngokuba yi-pulmonary chondroma).

Ifunyanwa njani iParaganglioma?

I-paraganglioma inokuba nzima ukuyifumanisa kuba yithumba elingaqhelekanga kwaye ngamanye amaxesha alibangeli zimpawu. Ngamanye amaxesha, oogqirha bafumana i-paragangliomas ngelixa besenza uvavanyo ngesinye isizathu.

Ugqirha unokurhanela ukuba i-paraganglioma ibangelwa kukubona ezi zinto zilandelayo:

• Imbali yakho epheleleyo yezonyango, ingakumbi nokuba kukho nabani na kusapho lwakho owakha waba ne-pheochromocytoma okanye i-paraganglioma.
• Uvavanyo olupheleleyo lomzimba nolwezonyango.
• Uhlobo lwezinye iimpawu. Umzekelo, ukuba une-high blood pressure engalawulwa ngonyango oluqhelekileyo.

Zeziphi iimvavanyo ezenziwayo koku?

Ugqirha wakho angasebenzisa ezi mvavanyo kunye neenkqubo ukuze abone ukuba unayo na i-paraganglioma:

• Uvavanyo lomzimba: Ugqirha wakho uza kukuhlola aze ahlole impilo yakho ngokubanzi, njengoxinzelelo lwegazi. Uza kubuza nangembali yakho yezonyango neyentsapho yakho, ingakumbi naziphi na iingxaki ezinxulumene namahomoni.
• Uvavanyo lomchamo lweeyure ezingama-24: Oku kuquka ukuqokelela isampuli yomchamo wakho kwixesha leeyure ezingama-24 kunye nokulinganisa ubungakanani beehomoni ze-adrenal ezibizwa ngokuba zii-catecholamines. Kukwakhangela nezinto eziveliswa xa ezi homoni ziqhekeka. Ukuba ezi catecholamines zikhona kumchamo wakho kumanqanaba aphezulu kunesiqhelo, oko kungaba luphawu lwe-paraganglioma.
• Uvavanyo lwe-catecholamine egazini: Olu vavanyo lulinganisa amanqanaba e-catecholamines egazini lakho. Njengoko bekutshiwo ngaphambili, lukwakhangela izinto eziveliswayo xa ezi hormone ziqhekeka. Ukuba ezi zifumaneka kumlinganiselo ophezulu kunesiqhelo egazini, inokuba luphawu lwe-paraganglioma.
• I-PET scan (positron emission tomography scan): I-PET scan ibandakanya ukufaka ikhemikhali ekhuselekileyo ene-radioactive (radiotracer) emzimbeni wakho kunye nokuthatha imifanekiso yamalungu akho kunye nezicubu usebenzisa isixhobo esibizwa ngokuba yi-PET scanner. Esi skeni sichonga iiseli ezisebenzayo kakhulu kunye neethumba ezifunxa ikhemikhali. Oku kunokunceda ekuqinisekiseni ukuba kukho ingxaki yempilo. Esi skeni silungile ngakumbi ekuchongeni indawo ye-paraganglioma.
• I-CT scan (i-computer tomography scan): I-CT scan yinkqubo ethatha uthotho lwee-X-rays kwiikona ezahlukeneyo ukuze idale imifanekiso eneenkcukacha zangaphakathi lomzimba wakho. Ugqirha wakho unokucebisa i-CT scan ukunceda ekufumaneni indawo yethumba (ngesiqhelo entanyeni).
• I-MRI scan (magnetic resonance imaging): I-MRI isebenzisa imagnethi, amaza erediyo, kunye nekhompyutha ukwenza uthotho lwemifanekiso eneenkcukacha zangaphakathi lomzimba wakho. Ugqirha wakho unokucebisa i-MRI ukuze ajonge kakuhle indawo apho ithumba likhoyo.

Emva kokuba ugqirha wakho ekufumanise ukuba une-paraganglioma, banokwenza olunye uvavanyo ukuze babone ukuba isasazeke na kwamanye amalungu omzimba wakho.

Ngaba Uvavanyo Lwemfuza Luyimfuneko?

Ukuba ufunyaniswe une-paraganglioma, ugqirha wakho uya kukucebisa ukuba ufumane ingcebiso nge-genetic ukuze ufumane ukuba unesifo esizuzwe njengelifa kwaye usemngciphekweni wokufumana eminye imingcipheko enxulumene naso.

Ugqirha wakho unokucebisa uvavanyo lwemfuza kwezi meko:

• Ukuba wena okanye umntu kusapho lwakho uneempawu ezinxulumene ne-pheochromocytoma okanye i-paraganglioma syndrome.
• Ukuba uneempawu zamanqanaba aphezulu kunesiqhelo ee-catecholamines egazini lakho okanye iimpawu ze-paraganglioma enomhlaza.
• Ukuba ukhe waba ne-paraganglioma ngaphambi kokuba ufikelele kwiminyaka engama-40.

Ukuba umcebisi wakho wezemfuza ufumana naluphi na utshintsho kwizakhi zofuzo kwiziphumo zovavanyo lwakho, mhlawumbi uya kucebisa ukuba amanye amalungu osapho lwakho (kwanabo bangenazo iimpawu kodwa abasengozini) nabo bavavanywe.

Iphathwa njani iParaganglioma?

Unyango lwe-paraganglioma luxhomekeke kwizinto ezininzi, kuquka:

• Ubungakanani bethumba.
• Nokuba ithumba linesifo somhlaza (elibi) okanye elingalunganga (elingenobungozi).
• Nokuba uneempawu ezibangelwa kukunyuka kwamanqanaba e-catecholamines.
• Ingaba ithumba likwindawo enye kuphela, okanye lisasazeke (lisasazeke) kwamanye amalungu omzimba?
• Nokuba ithumba lifunyenwe okokuqala, okanye ukuba lalikhe lanyangwa ngaphambili laza laphinda lavela.

Ukuba une-paraganglioma ebangela iimpawu ezibangelwa kukugqithisa kweehomoni, ugqirha wakho uya kukunika amayeza okulawula ezo mpawu. La mayeza angaquka:

• Amayeza alawula uxinzelelo lwegazi, umzekelo, ii-alpha-blockers .
• Amayeza okugcina isantya sentliziyo yakho sikwinqanaba eliqhelekileyo, umzekelo ii-beta-blockers .
• Amayeza athintela imiphumo yeehomoni ezikhutshwa ngokugqithisileyo yi-adrenal gland(s) yakho.

Iindlela zonyango lwe-paraganglioma zezi:

• Ukususwa kwesi sifo ngotyando.
• Unyango ngemitha.
• Unyango ngamachiza.
• Unyango lokukhupha isisu.
• Unyango olujoliswe kulo.

Kunye, wena kunye neqela lakho lezonyango niya kugqiba isicwangciso sonyango esifanela wena kunye nemeko yakho.

Ukususwa kwethumba ngotyando

Unyango oluphambili lwe-paraganglioma lutyando. Ngexesha lotyando lokususa ithumba, ugqirha wakho uza kujonga izicwili ezijikelezileyo kunye nee-lymph nodes ukuze abone ukuba ithumba lisasazekile na. Ukuba lisasazekile, ugqirha uza kususa izicwili ezichaphazelekayo, ukuba kunokwenzeka.

Uninzi lwee-paragangliomas zinokususwa kusetyenziswa iindlela ezingafunekiyo kangako, ezifana notyando lwe-laparoscopic . Oku kuquka ukwenza imingxunya embalwa eluswini lwakho kunye nokususa ithumba ngezixhobo ezikhethekileyo. Nangona kunjalo, iithumba ezinkulu zinokufuna utyando oluvulekileyo lwendabuko.

Emva kotyando, ugqirha wakho uza kujonga amanqanaba ee-catecholamines egazini okanye emchameni wakho. Ukuba amanqanaba ee-catecholamines abuyela esiqhelweni, olu luphawu lokuba zonke iiseli ze-paraganglioma zisusiwe.

Unyango lweMisebe

Unyango lwemitha lunyango lomhlaza olusebenzisa imisebe enamandla aphezulu yemitha ukubulala iiseli zomhlaza okanye ukuzithintela ukuba zingakhuli. Oku kwenziwa ngelixa kunciphisa umonakalo kwizicubu eziphilileyo ezingqongileyo.

Kukho iintlobo ezimbini zonyango lwe-radiation:

• Unyango lwemitha yangaphandle: Oku kuquka ukusebenzisa umatshini ongaphandle komzimba wakho ukuze uqondise imitha kwindawo apho umhlaza ukuyo.
• Unyango lwemitha yangaphakathi: Oku kubandakanya ukufaka into enemitha kwiinaliti, imbewu, iingcingo, okanye ii-catheters, ezithi emva koko zibekwe ngqo kwithumba okanye kufutshane nalo ngugqirha.

Uhlobo lonyango lwemitha olucetyiswa ngugqirha wakho luxhomekeke ekubeni umhlaza wakho ungowasekuhlaleni, ungowengingqi, ukude, okanye ubuyile. Oogqirha badla ngokusebenzisa unyango lwemitha lwangaphandle kunye/okanye unyango lwe-131I-MIBG ukunyanga ii-paragangliomas ezinomhlaza. Unyango lwe-131I-MIBG yindlela yokuhambisa into enemitha kwiintlobo ezithile zeeseli zomhlaza, ezithi emva koko zifakwe emzimbeni kwaye imitha eyikhuphayo ibulale iiseli.

Unyango ngamakhemikhali

Unyango oluqhelekileyo lwe-metastatic paraganglioma yi-chemotherapy. Oku kubandakanya ukusebenzisa amayeza okubulala iiseli zomhlaza, ukuzithintela ukuba zingahlukani, okanye ukuzithintela ukuba zingakhuli. I-chemotherapy idla ngokunikezelwa ngemithambo yegazi. Nangona olu lunyango olusebenzayo, lunokubangela iziphumo ebezingalindelekanga.

Unyango lwe-Ablation

Unyango lwe-ablation lukhetho lonyango olungenabungozi kangako olusebenzisa amaqondo obushushu aphezulu kakhulu okanye aphantsi kakhulu ukutshabalalisa iithumba. Unyango lwe-ablation olunceda ukubulala iiseli zomhlaza kunye neeseli ezingaqhelekanga luquka:

• Ukususwa kwee-radiofrequency: Oku kuquka ukusebenzisa amaza erediyo ukufudumeza nokutshabalalisa iiseli zomhlaza kunye neeseli ezingaqhelekanga. Amaza erediyo athunyelwa ngee-electrodes (izixhobo ezincinci eziqhuba umbane).
• I-Cryoablation: Olu nyango lusebenzisa i-nitrogen engamanzi okanye i-carbon dioxide engamanzi ukuze iqandiswe kwaye itshabalalise iiseli zomhlaza kunye neeseli ezingaqhelekanga.

Unyango olujoliswe kulo

Unyango olujoliswe ekujoliswe kulo lukhetho lonyango olusebenzisa amayeza okanye ezinye izinto ukuhlasela iiseli ezithile zomhlaza kuphela, ngaphandle kokulimaza iiseli eziphilileyo. Oogqirha basebenzisa unyango olujoliswe ekujongeni ukunyanga iiparagangliomas ezikude neziphindaphindayo.

Abaphandi okwangoku baphanda i-tyrosine kinase inhibitor ebizwa ngokuba yi-sunitinib.Kufundwa uhlobo oluthile lwesiyobisi ukuze kubonwe ukuba singanyanga njani ii-paragangliomas ezikude. Unyango lwe-Tyrosine kinase inhibitor luhlobo lonyango olujoliswe kulo oluthintela ukukhula kwethumba.

Ngaba uphuhliso lwe-paraganglioma lunokuthintelwa?

Ngelishwa, iiparagangliomas azinakuthintelwa. Nangona kunjalo, ukuba uneempawu ezithile ezizuzwe njengelifa kunye neejini ezikubeka emngciphekweni wokufumana iiparagangliomas, ingcebiso ngezofuzo inokukunceda ukuba uvavanyelwe iiparagangliomas kwaye mhlawumbi uzifumane kwangethuba.

Thetha nogqirha wakho ukuba izalamane zakho (abantakwenu nabazali) abakwinqanaba lokuqala baye baba ne-paraganglioma okanye i-pheochromocytoma, kunye/okanye ukuba unayo nayiphi na kwezi meko zemfuza:

• I-Multiple endocrine neoplasia 2 syndrome.
• Isifo seVon Hippel-Lindau (VHL).
• Uhlobo lwe-Neurofibromatosis 1.
• I-Hereditary paraganglioma syndrome.
• UCarney-Stratakis dyad.
• UCarney triad.

Ithini ingqikelelo kule meko?

Imbonakalo ye-paragangliomas, oko kukuthi, amathuba okuphila nokusinda, iyahluka ngokuxhomekeke kwizinto ezininzi. Phakathi kwazo:

• Apho ithumba likhona emzimbeni wakho kwaye likhulu kangakanani.
• Nokuba ngumhlaza okanye sele usasazeke kwamanye amalungu omzimba.
• Ingaba ithumba lisusiwe ngotyando, kwaye ukuba kunjalo, lingakanani ithumba elisusiweyo ngexesha lotyando?

Abantu abane-paraganglioma encinci engasasazekanga kwezinye iindawo zomzimba (engakhange isasazeke) banomlinganiselo wokusinda weminyaka emihlanu omalunga nama-95%. Nangona kunjalo, abantu abane-paraganglioma ephinde yavela emva konyango lokuqala okanye esasazeke kwezinye iindawo zomzimba (i-metastasized) banomlinganiselo wokusinda weminyaka emihlanu ophakathi kwama-34% nama-60% .

Kwakhona, kukho iiparagangliomas ezinzima, nokuba azikasasazekanga kakhulu, ezingenakususwa ngokupheleleyo ngotyando kuba zisasazeke ngokwaneleyo kwizicwili ezingqongileyo. Kwiimeko ezinjalo, ukukhutshwa kakhulu kwe-adrenaline kunye ne-noradrenaline kunokuba yingozi kwaye kube nzima ukunyanga.

Okubaluleke kakhulu, ii-paragangliomas, nokuba zinomhlaza okanye azinawo, ukuba azinyangwa, zinokubangela iingxaki ezinkulu, ezisongela ubomi ngenxa yobuninzi be-adrenaline kunye ne-noradrenaline ezikhuphayo.

Ezinye zezi ngxaki zezi:

• Isifo sentliziyo (cardiomyopathy).
• Ukudumba kwemisipha yentliziyo yakho (`myocarditis`).
• Ukopha okungalawulekiyo engqondweni yakho (ukuvaleka kwegazi ebuchosheni).
• Ukwanda kolwelo emiphungeni yakho (i-pulmonary edema).
• Uhlaselo lwentliziyo (`i-myocardial infarction`).
• Istroke.
• I-Coma.
• Ukufa.

Ndifanele ndimbone nini ugqirha?

Ukuba ufunyaniswe une-paraganglioma kwaye ufumana iimpawu ezikrokrisayo, bonana nogqirha wakho ngoko nangoko.

Ukuba ufumana iimpawu ze-paraganglioma, ezinje ngoxinzelelo lwegazi oluphezulu kunye nentloko ebuhlungu, thetha nogqirha wakho. Ekubeni i-paraganglioma ingaqhelekanga, kusabalulekile ukunyanga uxinzelelo lwegazi oluphezulu, nokuba akunakwenzeka ukuba unalo.

Ukuba ufumanisa ukuba omnye wezalamane zakho ezikwinqanaba lokuqala (abantakwenu, abazali) une-genetic syndrome efana ne-"Multiple endocrine neoplasia 2 syndrome" okanye i-"Von Hippel-Lindau (VHL) disease", buza ugqirha wakho malunga novavanyo lwe-genetic, njengoko oku kunokunyusa umngcipheko wakho wokuba ne-paraganglioma.

Yeyiphi imibuzo omele uyibuze ugqirha wakho?

Ukuba ufunyaniswe une-paraganglioma, kunokuba luncedo ukubuza ugqirha wakho le mibuzo:

• Kutheni ndibe ne-paraganglioma?
• Ngaba abantwana bam kunye/okanye izalamane zam zingaba ne-paraganglioma?
• Ziziphi iindlela zonyango endinazo?
• Zithini iziphumo ebezingalindelekanga zonyango olwahlukeneyo?
• Ndingazilawula njani iimpawu zam?

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

I-Paraganglioma yimeko engaqhelekanga, kodwa kubalulekile ukuba uyiqaphele. Ukuba uneempawu ezingapheliyo ezinzima ukuziqonda, ingakumbi uxinzelelo lwegazi oluphezulu ngequbuliso, ukubila, okanye ukubetha kwentliziyo ngokukhawuleza, kububulumko ukufuna ingcebiso kagqirha kunokuzithatha njengento eyenzekayo nje.

Nangona unobangela we-paraganglioma ungaziwa rhoqo, kukho izinto ezithile ezinokubangela i-genetic. Ngoko ke, ukuba kukho umntu kusapho lwakho oye waba ne-paraganglioma okanye i-pheochromocytoma, uvavanyo lwe-genetic lunokukunceda ufumane umngcipheko wakho kunye nokuba unokuba nezinye iingxaki zempilo. Ukuba unemibuzo malunga noku, ungathandabuzi ukuthetha nogqirha wakho. Bakho ukukunceda.

I - Paranglioma, i-Paranglioma, i-Pheochromocytoma, iiseli zeChromaffin, iiCatecholamines, iiHormones, iiTumors, umhlaza, iimpawu, uxinzelelo lwegazi oluphezulu, izifo zemfuza