Ngaba ngamanye amaxesha uziva udiniwe ngendlela engaqhelekanga ngaphandle kwesizathu? Okanye umane uzikrwela nje ulusu lwakho? Uninzi lwethu aluzinaki kakhulu ezi zinto. Kodwa ezi zinokuba ziimpawu zokuqala zesifo esingathethi kakhulu ngaso, esichaphazela isibindi buthule. Namhlanje siza kuthetha ngesinye sezifo ezinjalo, `(Primary Biliary Cholangitis)`, okanye i-PBC ngamafutshane. Nangona eli ligama eloyikekayo, wakuba uliqonda ngokuchanekileyo , ukulilawula akunzima njengoko ucinga.
Kalula nje, yintoni i-PBC?
Cinga ngesibindi sethu njengomzi-mveliso omkhulu. Ngaphakathi kweli shishini, kuveliswa izinto ezininzi ezibalulekileyo emzimbeni, kwaye neetyhefu eziyingozi nazo ziyasuswa emzimbeni. Eyona nto ibalulekileyo enceda kulo msebenzi ibizwa ngokuba yi-"bile". Le nyongo iveliswa sisibindi. Ezi zifana nemijelo emincinci efana nemibhobho, oko kukuthi, imibhobho yenyongo. Le nyongo inceda ekunyibilikiseni amafutha ekutyeni esikutyayo, ifunxe iivithamini emzimbeni, kwaye isuse i-cholesterol enobungozi kunye neetyhefu emzimbeni.
Ngoku, kwimeko ebizwa ngokuba yi-PBC, iiseli zethu zomzimba ziqala ngempazamo ukuhlasela ezi ducts zincinci ze-bile esibindini. Kufana nemikhosi yethu yokuzikhusela ehlasela indawo ebalulekileyo yelizwe lethu. Olu hlaselo lonakalisa i-ducts ze-bile kwaye luyitshabalalise kancinci kancinci. Emva koko i-bile ayikwazi ukuhamba kakuhle kwaye ibambeke ngaphakathi kwesibindi. Le duct ibambekileyo iqala ukonakalisa iiseli zesibindi. Ekuhambeni kwexesha, lo monakalo unokubangela amanxeba esibindini. Oku sikubiza ngokuba yi-'(cirrhosis)'.
I-PBC iqhubeka njani?
I-PBC ayiphuhli ngequbuliso. Sisifo esiphuhla kancinci kwiminyaka emininzi. Yiyo loo nto kusenokungabikho zimpawu kwizigaba zokuqala. Usenokungaluboni utshintsho kangangeminyaka.
Abanye abantu banokufumana iimpawu ezifana nokudinwa kunye nokudumba kwesikhumba kwasekuqaleni kwesi sifo. Abanye banokufumana ezi mpawu kamva kwesi sifo. Ubunzima bezi mpawu buyahluka ukusuka kumntu ukuya komnye. Nangona kunjalo, oogqirha bafumanise ukuba ukuba iimpawu zinzima kwasekuqaleni kwesi sifo, oko kunokubonisa ukuba isifo sinokuqhubeka ngokukhawuleza.
Kodwa eyona nto ibalulekileyo kukuba ukuba esi sifo sifunyenwe kwangethuba kwaye kuqaliswe unyango olufanelekileyo , izinga lokuqhubela phambili kwesi sifo linokulawulwa kakhulu. Abantu abaninzi bayakwazi ukuphila ubomi obuqhelekileyo ngaphandle kokungena kwizigaba ezinzima zesifo.
Amanqanaba amane aphambili esifo se-PBC
Oogqirha nabaphandi bahlukanise i-PBC ibe ngamanqanaba amane aphambili, kuxhomekeke kubungakanani bomonakalo wesibindi. Makhe sijonge okwenzekayo kwinqanaba lokuqala.
Inqanaba 1: Inqanaba lePortal
Eli linqanaba lokuqala lesi sifo. Ngeli xesha, imibhobho yenyongo emincinci esibindini sakho iqala ukonakala.
- kuqhubekani?
Iiseli ze-T, okanye ii-T lymphocytes, luhlobo lweeseli ezimhlophe zegazi ezikhusela imizimba yethu kwizifo. Ngokwesiqhelo, zilwa neentsholongwane ezingena emzimbeni. Nangona kunjalo, kwi-PBC, ezi seli ze-T zichonga ngempazamo iiseli ze-bile duct ezisempilweni esibindini "njengotshaba" kwaye ziqala ukuzihlasela. Oku kubangela ukudumba okujikeleze imibhobho ye-bile. Lo monakalo wenzeka kwindawo ekhethekileyo yesibindi ebizwa ngokuba yi-portal area, apho imithambo yegazi kunye nemibhobho ye-bile idibana khona.
- Ngaba kukho naziphi na iimpawu?
Amaxesha amaninzi, usenokungabi nazimpawu kweli nqanaba lokuqala. Ngenxa yoko, usenokungazi nokuba unesi sifo. Eli nqanaba lokuthula lisenokuqhubeka iminyaka.
Iimpawu zisenokungabonakali de kube yiminyaka emi-5 okanye eli-10 kamva. Xa iimpawu ziqala, umntu oqhelekileyo unokuphila nesi sifo kangangeminyaka eli-10. Nangona kunjalo, ukuba kwenziwe utyando lwesibindi oluphumelelayo, izinga lokusinda leminyaka eli-10 linyuka liye kuma-65%.
Amanqanaba Amva (Amanqanaba Amva - 2, 3 kunye no-4)
Emva kwesigaba sokuqala, esi sifo siqhubeka kancinci kancinci siye kwinqanaba lesibini, lesithathu, nelesine.
- Inqanaba lesi-2: Ukonakala kwimibhobho yenyongo kuyanda.
- Inqanaba lesi-3: Kuqala ukuba nezibazi esibindini. Oku kukuqala kwemeko ebizwa ngokuba yi-fibrosis.
- Inqanaba lesi-4: Kuvela amanxeba amaninzi esibindini, nto leyo ekhokelela kwimeko enzima ebizwa ngokuba yi-cirrhosis. Ngeli xesha, isibindi asisakwazi ukusebenza kakuhle.
Ngugqirha wakho kuphela onokukunika ingcaciso engcono kakhulu kwimeko nganye kwezi, ngokusekelwe kwimeko yakho ethile.
Zeziphi iimpawu ekufuneka siziqwalasele?
Kukho iimpawu ezininzi ezinokwenzeka nge-PBC. Ezi azenzeki ngendlela efanayo kuye wonke umntu. Kodwa kubalulekile ukuba uzazi ezi mpawu.
| Uphawu | Inkcazo |
|---|---|
| Ukudinwa | Oku akukokudinwa nje okuqhelekileyo. Kukuvakalelwa kukudinwa nokuba ulala kangakanani na. Usenokuziva udiniwe kangangokuba awukwazi ukusebenza emini. |
| Ulusu olurhawuzelelayo | Ukurhawuzelela kunokwenzeka, ingakumbi ezintendeni zezandla nasezinyaweni. Ngamanye amaxesha oku kurhawuzelela akunakunyamezeleka. |
| Amehlo nomlomo owomileyo | Olu luphawu olunokwenzeka kunye nenye imeko yezonyango, i-Sjögren's syndrome. |
| Intlungu yamathambo namalungu | Ngokuhamba kwexesha, iimeko ezinje ngobuthathaka bamathambo (i-osteoporosis) zinokuvela. |
| Iimpawu zokuqala kamva | Ukutyheli kolusu namehlo (i-jaundice), ulwelo esiswini, ukudumba kwemilenze, kunye nokuchitheka kwamafutha phantsi kolusu (ii-xanthomas) kunokubonakala njengoko isifo siqhubeka. |
Ukuba uqhubeka ufumana enye okanye ngaphezulu kwezi mpawu, kubalulekile ukubona ugqirha wakho ngoko nangoko ukuze akunike icebiso. Musa ukucinga nje ukuba kukudinwa okanye ulusu olomileyo.
Ukuxilongwa kwangoko kunokutshintsha ubomi!
Xa sithetha nge-PBC, akufuneki soyike, kodwa kufuneka silumke. Kuba impilo yakho yexesha elizayo ixhomekeke ekubeni ukhawuleza kangakanani na ukufumanisa esi sifo kwaye uqale unyango lwaso.
Ngokufumanisa isifo kwangethuba nokuqala amayeza afanelekileyo, umonakalo kwisibindi unokulawulwa kakhulu. Oku kuthetha ukuba isifo sinokumiswa okanye sirhoxiswe de sifikelele kwinqanaba elibi. Emva koko ungaphila ubomi obusempilweni ngaphandle kwempembelelo ingako kwimisebenzi yakho yemihla ngemihla.
Kodwa ukuba isifo sifunyenwe emva kwexesha, okanye ukuba unesimo esibi kakhulu nesikhula ngokukhawuleza sesi sifo, isibindi sinokonakala kakhulu kwaye sinokuba buthathaka kwisibindi. Kwiimeko ezinjalo, ukufakelwa kwesibindi yindlela ekuphela kwayo yokusindisa ubomi bakho. Ke ngoko, ukuxilongwa kwangoko yeyona nto ibalulekileyo kule nkalo.
Umyalezo Wokuya Ekhaya
- I-PBC sisifo esiqhubekayo esonakalisa imibhobho yenyongo yesibindi.
- Kusenokungabikho zimpawu ekuqaleni, kodwa ukudinwa okungachazwanga kunye nokurhawuzelelwa lulusu zisenokuba zezona mpawu ziphambili zokuqala.
- Ukufunyanwa kwesi sifo kwangethuba kubaluleke kakhulu, kuba kunokunceda ukulawula ukuqhubela phambili kwaso.
- Ukuba uneempawu ezikrokrisayo, akukaze kube kudala ukuthetha nogqirha wakho ngazo.
- Ngonyango olufanelekileyo, uninzi lwabantu abane-PBC banokuphila ubomi obusempilweni nobuqhelekileyo.
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