Ngaba nawe unengxaki yokuginya ukutya? Masifunde ngePlummer-Vinson syndrome?

Ngaba ukufumanisa kunzima ukuginya ukutya? Okanye uziva udiniwe ngalo lonke ixesha, uziva udiniwe? Ngamanye amaxesha ezi zinto zibonakala ziqhelekile, kodwa kusenokuba kukho esinye isizathu emva kwazo. Namhlanje siza kuthetha ngemeko yezonyango engaqhelekanga kodwa ebalulekileyo. Leyo yiPlummer-Vinson syndrome.

Yintoni iPlummer-Vinson syndrome?

Ngamafutshane, iPlummer-Vinson syndrome (PVS) yimeko apho iimpawu ezintathu ezinxulumeneyo zenzeka kunye. Oogqirha ngamanye amaxesha babiza oku ngokuthi "unxantathu," oku kuthetha "indibaniselwano yezintathu." Makhe sijonge ukuba zeziphi ezi meko zintathu:

1. I-anemia yokunqongophala kwe-iron: Oku kwenzeka xa umzimba wakho ungenayo i-iron eyaneleyo yokwenza iproteni ebizwa ngokuba yi-hemoglobin kwiiseli zakho ezibomvu zegazi. Uyazi, i-hemoglobin yiyo ethwala i-oksijini ukuya kwiseli nganye emzimbeni wakho. Ngoko ke, xa ungenayo i-iron eyaneleyo, i-hemoglobin ayiveliswanga kakuhle, kwaye umzimba wakho awufumani i-oksijini oyifunayo. Oku kubangelwa ziimpawu ezifana nokudinwa kunye nokuphaphatheka.

2. Iintambo zomqala: Oku kwenzeka xa izicubu ezincinci, ezingezizo eziqhelekileyo zisenzeka ngaphakathi komqala wakho, okanye kumbhobho wokutya. Cinga ngayo njengentambo yesigcawu eyenzeka kumqala wakho. Oku kubangela ukuba umqala ube mxinwa kwaye uvaleke. Oku kwenza kube nzima ukuba ukutya kudlule.

3. Ubunzima bokuginya (iDysphagia): Eli ligama abathi oogqirha balibiza ngokuba bunzima bokuginya ukutya neziselo ngenxa yemibhobho yomqala ekhankanyiweyo apha ngasentla. Abanye abantu banokuba nobunzima bokuginya kungekuphela nje ukutya okuqinileyo kodwa nolwelo.

Oku kubizwa ngamanye amagama. Elinye libizwa ngokuba yi-sideropenic dysphagia. Kwaye e-United Kingdom, oko kukuthi, eNgilane, kuthiwa yi-Paterson-Brown Kelly syndrome.

Nantsi into ekungafanele uyoyike. Abantu abane-Plummer-Vinson syndrome (PVS) kuthiwa banomngcipheko ophezulu kancinci wokuba nomhlaza womqala okanye umhlaza we-hypopharyngeal kamva ebomini. Nangona kunjalo, lo ngumngcipheko nje . Ugqirha wakho uza kukujonga rhoqo aze akujonge njengoko kufuneka ukuze abone naziphi na iimeko ezinjalo kwangethuba.

Zithini iimpawu zoku?

Kulungile, ngoku makhe sibone ukuba zeziphi iimpawu eziboniswa ngumntu one-Plummer-Vinson syndrome (PVS). Ezi mpawu azibonakali kubo bonke abantu ngendlela efanayo, kwaye abanye abantu banokuba nazo ezinye zeempawu.

• Ukudinwa nokudinwa ngalo lonke ixesha: Olu luphawu olukhulu lokungabikho kwe-iron emzimbeni. Uziva udiniwe nasemva kokwenza imisebenzi emincinci kwaye uzive ulele imini yonke.
• Ubunzima bokuphefumla (ukuphelelwa ngamandla): Usenokuziva uphelelwa ngamandla, kungekuphela nje xa uhamba kancinci, unyuka izinyuko, kodwa ngamanye amaxesha naxa umile nje.
• Ubunzima bokuginya ukutya:Olu lolona phawu lubalaseleyo lwesi sifo. Ingakumbi xa uginya ukutya okuqinileyo, okufana nerayisi, isonka, inyama kunye nentlanzi, kukho imvakalelo yokuxinana emqaleni nasesifubeni. Abanye abantu kufuneka basele amanzi amancinci ukuze baginye ukutya. Nangona ukutya okuqinileyo kunzima ekuqaleni, kamva kunokuba nzima nokuginya ulwelo.
• Ulwimi luyavuvukala, ludumbe, lube bomvu (glossitis): Ulwimi luba bushelelezi, lube bomvu, kwaye ngamanye amaxesha lunokuziva ngathi luyatsha.
• Umlomo owomileyo (xerostomia): Ingaphakathi lomlomo livakala lomile ngalo lonke ixesha, kwaye kukho imvakalelo yokungabikho kwamathe.
• I-angular cheilitis: Iikona zomlomo ziyaqhekeka, zibe bomvu, kwaye zibe buhlungu.
• Iinzipho ziyaqina kwaye zithe tyaba njengeecephe: Iinzipho zibuthathaka kakhulu kwaye ziyaphuka lula. Ngamanye amaxesha iinzipho ziyatshona embindini, njengecephe (koilonychia).
• Ukudumba kwe-thyroid gland kunye namaqhuma (ii-thyroid nodules): I-thyroid gland, ekwindawo engaphambili entanyeni, inokukhula ize ivakale ngathi yiqhuma.
• I-Splenomegaly: I-spleen sisitho esikwicala eliphezulu lasekhohlo lesisu sethu. Ingadumba nakule meko, kodwa ayisoloko ibangela naziphi na iimpawu ezinkulu.

Yintoni isizathu soku?

Enyanisweni, abaphandi abakaqiniseki ngokupheleleyo ukuba yintoni ebangela iPlummer-Vinson syndrome (PVS). Kodwa kukho izinto ezimbalwa abazicingayo nabacinga ukuba zibalulekile:

• Ukunqongophala kwesinyithi yinto ebangela ukurhaneleka: Abantu abaninzi bacinga ukuba ukunqongophala kwesinyithi ixesha elide kubangela ukuba izihlunu ezikumphimbo zibe buthathaka kwaye zenze iintambo. Isinyithi siyafuneka kwii-enzymes ezininzi emzimbeni wethu.
• Ukunqongophala kwezondlo: Kukho inkolelo yokuba kungekuphela nje i-iron, kodwa nezinye iivithamini kunye neeminerali nazo zinokuchaphazela oku.
• Izifo ezichaphazela umzimba ngokwawo: Usenokuba ukhe weva ngezifo ezifana ne-rheumatoid arthritis kunye nesifo se-celiac. Ezi zizifo ezichaphazela umzimba ngokwawo ezenzeka xa umzimba wethu wokuzikhusela uhlasela iiseli zethu. Ngoko ke, ekubeni abanye abantu abane-PVS nabo benezi zifo, oogqirha bacinga ukuba oku kusenokuba kunxulumene nenkqubo yomzimba yokuzikhusela.
• Impembelelo yemfuza: Abanye bakholelwa ukuba le yimeko yemfuza, nto leyo ethetha ukuba ukuba umntu othile kusapho unayo, nabanye banokuba nayo.

Kodwa ezi ziseziingcamango nje. Kufuneka uphando olongezelelekileyo ukuze kufunyanwe unobangela ochanekileyo.

Ngubani osengozini enkulu yokuphuhlisa oku?

Isifo iPlummer-Vinson syndrome (PVS) sisifo esingaqhelekanga kakhulu . Asibachaphazeli bonke abantu. Nangona kunjalo, ngokwezibalo, sixhaphake kakhulu kubafazi abamhlophe. Sidla ngokuchaphazela abafazi abaneminyaka ephakathi, abaphakathi kweminyaka engama-40 nama-70.Le yeyona nto ixhaphakileyo. Nangona kunjalo, kunqabile kakhulu, oko kukuthi, kunqabile kakhulu, ukuba kuxelwe ukuba kwenzeka kubantu abancinci kwanakwiintsana ezincinci.

Kwixesha elidlulileyo, oko kukuthi, ekuqaleni kweminyaka yoo-1900, esi sifo sasixhaphakile kumazwe aseScandinavia (umz., eSweden, eNorway). Nangona kunjalo, ngasekupheleni kweminyaka yoo-1900, oko kukuthi, kwiminyaka embalwa edlulileyo, besisele sinqabile kakhulu kuloo mazwe. Isizathu esiphambili soku kucingelwa ukuba kukuphucuka kwesimo sesondlo sabantu baloo mazwe ngelo xesha, ingakumbi ukufumaneka lula kokutya okutyebileyo kwi-iron.

Ziziphi iingxaki ezinokubakho ze-PVS?

Njengoko besikhe sathetha ngayo ngaphambili, abantu abane-Plummer-Vinson syndrome (PVS) bafunyenwe benomngcipheko ophezulu kancinci wokuba nomhlaza womqala kunye nomhlaza we-hypopharyngeal, umhlaza okwinxalenye esezantsi yomphimbo, obizwa ngokuba yi-hypopharynx, kunabantu abangenayo i-PVS.

Kodwa ungoyiki oku. Asinguye wonke umntu one-PVS oza kuba nomhlaza. Le yingxaki nje.

Ngenxa yokuba esi sifo sinqabile, akukho datha yophando eyaneleyo yokuchaza ukuba bangaphi abantu abane-PVS abafumana umhlaza.

Kodwa ukuba unale meko, ugqirha wakho uza kuzama ukubona nantoni na efana nomhlaza kwasekuqaleni , kuba kukho ithuba elikhulu lonyango nokunyangwa. Yiyo loo nto kubalulekile ukuya kuhlolwa rhoqo, njengoko ugqirha wakho esitsho.

Ifunyanwa njani iPlummer-Vinson syndrome (PVS)?

Ukuba uneempawu ezichazwe apha ngasentla, xa usiya kugqirha, uza kukubuza imibuzo aze akuhlole. Emva koko, baza kuyalela uvavanyo lwegazi kunye neenkqubo ezithile zokuthatha imifanekiso ukuqinisekisa ukuba unayo na i-PVS.

• Uvavanyo lwegazi: Olu vavanyo lujonga ikakhulu ukuba kukho i-anemia ebangelwa kukunqongophala kwe-iron.
• Ubalo lwegazi olupheleleyo (CBC): Oku kunokujonga izinto ezininzi ezifana neseli yakho ebomvu yegazi, iseli emhlophe yegazi, kunye namanqanaba e-hemoglobin.
• I-Peripheral Blood Smear (PBS): Oku kuquka ukujonga isampuli yegazi phantsi kwe-microscope ukujonga imo kunye nobukhulu beeseli ezibomvu zegazi. Xa zingenazo i-iron, iiseli ezibomvu zegazi zisenokuba zincinci kwaye zibe mthubi (microcytic, hypochromic).
• Uvavanyo lwenqanaba lesinyithi: Uvavanyo olufana ne-serum ferritin, i-serum iron, kunye ne-TIBC (Total Iron Binding Capacity) lunokunika umbono wobungakanani besinyithi emzimbeni.

• Uvavanyo lwemifanekiso: Olu lukhangela imingxunya yesisu kunye nesizathu se-dysphagia.
• I-endoscopy ephezulu (OGD - Oesophago-Gastro-Duodenoscopy):Kule nto, kufakwa ityhubhu enekhamera encinci eqhotyoshelweyo ngomlomo kwaye kuhlolwa umqala, isisu, kwaye inxalenye yokuqala yamathumbu amancinci. Oku kukuvumela ukuba ubone ngokuthe ngqo ukuba kukho iintambo. Ukuba kuyimfuneko, iqhekeza elincinci lesicwili (i-biopsy) lingathathwa ukuze lihlolwe.
• I-Barium swallow / I-Esophagram: Kolu vavanyo, usela into ebizwa ngokuba yi-barium kwaye uthathwe imifanekiso ye-X-ray. I-barium yenza i-esophagus ibonakale kwi-X-ray, ikuvumela ukuba ubone naziphi na iindawo ezivalekileyo okanye ezijiyileyo.
• I-Videofluoroscopy: Olu luvavanyo lwe-X-ray. Lurekhoda ividiyo yakho uginya iintlobo ezahlukeneyo zokutya. Oku kunokukunceda ubone ngqo indlela oginya ngayo kunye nendawo apho ingxaki ikhoyo.

Ngamanye amaxesha ugqirha unokufuna ukwenza uvavanyo oluthe kratya ukuze afumane unobangela wokwenene wokungabikho kwesinyithi. Umzekelo, banokukhangela izilonda zesisu okanye ukopha emathunjini.

Iphathwa njani le nto?

Kukho iinjongo ezimbini eziphambili xa kunyangwa i-Plummer-Vinson syndrome (PVS). Enye kukulungisa ukungabikho kwe-iron , enye kukujongana nobunzima bokuginya ukutya .

• Unyango lokunqongophala kwesinyithi:
• Eyona nto iphambili kukubonelela umzimba wakho nge-iron oyifunayo. Ungathatha izongezo ze-iron koku. Ufanele uzithathe kanye njengoko ugqirha wakho ekuxelela, ixesha elide akuxelela lona.
• Kwabanye abantu, ukuba iipilisi zesinyithi ezithethwayo azifunxwa kakuhle, okanye ukuba isinyithi asifumaneki kakuhle, isinyithi ngamanye amaxesha sinokufakwa ngemithambo yegazi (IV - Intravenous iron).
• Ukuba unenye ingxaki yempilo ebangela ukungabikho kwesinyithi (umz., ukopha kakhulu exesheni, ii-hemorrhoids, izilonda zesisu), ngokuqinisekileyo kufuneka uyinyange loo nto.

• Unyango lobunzima bokuginya (i-Dysphagia):
• Kwiimeko ezininzi, xa olu nqongophala lwesinyithi lunyangwa, kwaye umzimba ufumana isinyithi, iintambo zomqala ziyanyamalala phantse ngokuzenzekelayo, kwaye ubunzima bokuginya ukutya buyancitshiswa kakhulu.
• Masithi unyango lwesinyithi lodwa aluyinyangi ngokupheleleyo ingxaki yakho yokuginya. Ukuba kunjalo, kukho inkqubo yokwandisa, okanye yokwandisa, umphimbo wakho. Ibizwa ngokuba kukwandisa umphimbo . Oku kwenziwa ngexesha le-endoscopy. Isixhobo esincinci esifana nebhaluni sifakwa kwindawo encinci yomphimbo kwaye sivuthelwe okanye sivuthelwe ukuze sandise umphimbo. Olu asilotyando olukhulu, kodwa yinkqubo elula, edla ngokungabangeli ntlungu equka ukungasikwa umphimbo. Abanye abantu banokufuna ukuba oku kwenziwe ngaphezu kwesihlandlo esinye.

Iyintoni ikamva lale meko?

Enyanisweni, umntu one-Plummer-Vinson syndrome (PVS) unokulindela iziphumo ezilungileyo kunye nokuchacha .

Kwabaninzi abantu, xa ukungabikho kwe-iron kulungisiwe, iimpawu ze-anemia (ezifana nokudinwa kunye nokuphefumla kancinci) ziyancipha kakhulu. Kwakhona, ubunzima bokuginya ukutya buyaphucuka kakhulu.

Ukuba ubunzima bokuginya abusonjululwa ngonyango lwesinyithi kuphela, unyango lokwandisa umqala olukhankanyiweyo ngaphambili ludla ngokuphucula ubunzima bokuginya. Abanye abantu banokufuna olu nyango lokwandisa umqala izihlandlo ezingaphezu kwesinye. Kodwa yinkqubo elula kakhulu kwaye ayinabungozi.

Ugqirha wakho usenokufuna ukwenza i-surveillance endoscopy ukujonga iimeko ezifana nomhlaza kumqala wakho okanye emqaleni. Kodwa khumbula, ukuba ne-PVS yinto ebangela umhlaza kuphela . Ukuba ne-PVS akuthethi ukuba ngokuqinisekileyo uza kuba nomhlaza.

Thetha nogqirha wakho malunga nendlela ukuba ne-PVS okuchaphazela ngayo umngcipheko wakho womhlaza, indlela yokuyinyamekela ukususela kwixesha elizayo, kunye nokuba kufuneka uvavanywe kangaphi.

Ngaba iPlummer-Vinson Syndrome (PVS) ingathintelwa?

Oogqirha abakayazi kakuhle into ebangela iPlummer-Vinson syndrome (PVS), ngoko ke akunakwenzeka ukuqiniseka ukuba ikho na indlela ethile yokuyithintela.

Nangona kunjalo, ukuthintela ukunqongophala kwesinyithi kunye nokunyanga ngokukhawuleza ukuba unesifo esibangela ukunqongophala kwesinyithi kunokunciphisa umngcipheko wakho wokuba ne-PVS.

Ngoko ke, licebo elihle ukuqinisekisa ukuba ufumana i-iron eyaneleyo kwizinto ozityayo neziselayo. Faka ukutya okutyebileyo kwi-iron (umz. inyama ebomvu, ii-peas, ispinatshi, iilentile, i-soy) ekutyeni kwakho.

Ndifanele ndimbone nini ugqirha?

Ukuba uneempawu ze-anemia (umzekelo, ukudinwa okunganyamezelekiyo, ukuphefumla okunzima rhoqo, ulusu olukhanyayo), kwaye ukuba ezo mpawu aziphucuki emva kweeveki ezimbini, qiniseka ukuba ubona ugqirha.

Kwakhona, ukuba uziva ngathi unengxaki yokuginya ukutya, ingakumbi ukuba uziva ngathi ubambeke kukutya okuqinileyo , kwaye imeko ayiphucuki, kungcono ukubona ugqirha ukuze akunike iingcebiso kunokuba ungakunaki.

Ndingayibuza ntoni ugqirha?

Xa usiya kugqirha, mbuze ngezinto ezikuxhalabisayo nezoyikisayo. Umzekelo, ungabuza imibuzo efana nale:

• Yintoni enokuba yimbangela yokuba ndibe nale anemia?
• Zeziphi iimvavanyo ekufuneka ndizenze ukuze ndiqiniseke ukuba ndinayo na iPlummer-Vinson syndrome (PVS)?
• Luhlobo luni lonyango olundicebisayo?
• Ngaba kuya kufuneka ndenze utyando lokukhulisa umqala ukuze kulungiswe i-dysphagia yam? Kuza kufuneka ndenze utyando kangaphi?
• Ngaba ndifanele ndikhathazeke ngengozi yokuba nomhlaza kwixesha elizayo? Ndingenza ntoni ngayo?

Ukuba ucinga ukuba uneempawu zePlummer-Vinson syndrome (PVS), bona ugqirha ngoko nangoko. Akunyanzelekanga ukuba uphile nokudinwa okungapheliyo okubangelwa yi-anemia. Akunyanzelekanga ukuba uphile nentlungu yokuginya (i-dysphagia) eyenza ukutya kube ngumsebenzi onzima. Ngamanye amaxesha isisombululo silula njengeepilisi ezimbalwa zesinyithi. Ukuba akunjalo, unokufumana isiqabu ngokwandisa umphimbo wakho. Nangona kunjalo, kukho unyango olunokukunceda uzive ungcono .

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule

I-Plummer-Vinson syndrome (PVS) yimeko engaqhelekanga. Nangona kunjalo, iimpawu zayo eziphambili yi-iron deficiency anemia, ubunzima bokuginya (dysphagia), kunye ne-esophageal webs . Ukuba udinwa rhoqo, ubunzima bokuginya, okanye ulwimi olubuhlungu, kubalulekile ukubona ugqirha endaweni yokuyithatha njengento eqhelekileyo.

Kukho unyango olufanelekileyo lwe-PVS. Kwiimeko ezininzi, iimpawu ezininzi ziyaphucuka xa ukungabikho kwe-iron kulungisiwe kwaye umphimbo uvulekile ukuba kuyimfuneko.

Nangona sithetha ngomngcipheko womhlaza, khumbula ukuba ngumngcipheko nje kuphela. Ukuba uthetha nogqirha wakho, ufumane uvavanyo olufunekayo, kwaye ufumane unyango olufanelekileyo, ungahlala usempilweni. Ngoko ke ungoyiki nantoni na, kwaye ukuba unengxaki, funa ingcebiso yezonyango ngokukhawuleza. Impilo yakho ixabiseke kakhulu kuwe!

Isifo sePlummer -Vinson, i-PVS, ukungabikho kwesinyithi, i-dysphagia, ubunzima bokuginya, ii-varices zomqala, i-anemia