Ingaba iiseli ezibomvu zegazi ezikwigazi lakho ziyatshintsha imilo? Masithethe nge-(Poikilocytosis)!

Ngaba ngamanye amaxesha uziva udiniwe kwaye udiniwe ngaphandle kwesizathu? Okanye ngaba ugqirha wakhe wajonga ingxelo yakho yovavanyo lwegazi waza wathi into efana nale, "Kukho utshintsho oluncinci kwimo yeeseli zakho ezibomvu zegazi?" Ngamaxesha anjalo, elinye lamagama esiwavayo ngu-`(Poikilocytosis)` (elibizwa ngokuba yi-poi-ki-lo-say-to-sis). Musa ukoyika kakhulu xa usiva eli gama. Esi asisosifo, kodwa singaba luphawu lokuba kukho enye into eyenzekayo emzimbeni wethu. Ngoko ke, kubaluleke kakhulu ukuqaphela oku.

Yintoni kanye kanye `(iPoikilocytosis)`?

Ngamafutshane, "iPoikilocytosis" ithetha ukuba inani elikhulu (oko kukuthi, ngaphezulu kwe-10%) yeeseli ezibomvu egazini lethu zinemilo engaqhelekanga. Ngoku usenokuba ucinga, "Ngoko kutheni imo yeeseli ezibomvu zegazi ibalulekile?"

Khawucinge nje, zonke ezinye iiseli, izicwili, kunye namalungu omzimba wethu zidinga amandla ukuze ziphile kwaye zisebenze. Loo mandla anikwa yioksijini. Ngubani owaziyo, le oksijini, njengokuzisa isilinda segesi ekhaya, ithwalwa emzimbeni wonke? Ziiseli zethu ezibomvu zegazi ezo. Ngokwesiqhelo, ukuba uthatha iiseli ezibomvu zegazi eziphilileyo, zonke zilingana ngobukhulu kunye nemilo. Njengengqekembe engqukuva (njengediski) egobile kancinci kumacala omabini.

Ngoko ke, ukuba imo yezi seli zibomvu zegazi iyatshintsha (`(Poikilocytosis)`) okanye ubungakanani buyatshintsha (kukho enye ebizwa ngokuba yi`(Anisocytosis)`), azikwazi ukuthwala ioksijini ngokufanelekileyo. Kulapho ke sifumana khona iimeko ezifana ne -anemia (ukungabikho kwegazi egazini). Oko kuthetha ukuba iiseli zomzimba azifumani ioksijini eyaneleyo, oko kuthetha amandla.

Zithini iimilo ezingaqhelekanga zeeseli ezibomvu zegazi? (iiPoikilocytes)

Oogqirha bahlula la maseli abomvu egazi aneemilo ezingaqhelekanga (akwabizwa ngokuba yi-'Poikilocytes') ngokwembonakalo yawo. Ukuba une-'(Poikilocytosis)' kwisampulu yegazi, ungabona enye okanye ezingaphezulu kwezi zilandelayo:

• Ii-acanthocytes / ii-Spur cells : Ezi zifana nesebe elinameva. Zineeprotrusions ezinde, ezibanzi, ezifana neespike eziphuma kwi-membrane yeseli.
• IiCodocytes / Iiseli ezijoliswe kuzo : Ezi zifana nebhodi ekujoliswe kuyo. Kukho isangqa esimnyama embindini.
• IiDacrocytes / Iiseli zeTeardrop : Zimile okweTeardrop. Elinye icala leseli libhityile kwaye litsolo.
• Ii-Drepanocytes / Iiseli zeSickle : Ezi ziiseli ezibhityileyo, ezimile okwesickle ezinokubonwa kubantu abanesifo se-sickle cell.
• Ii-Echinocytes : Njenge-sea urchin, iseli igqunywe yi-spines kumgama olinganayo kuyo yonke indawo.
• Ii-Elliptocytes / ii-Ovalocytes okanye ii-Cigar cells : Ezi zimile okweqanda kwaye zinde ngokungaqhelekanga. Zinokwahluka ngobukhulu ukusuka kwiqanda ukuya kwi-cigar.
• I-Schistocytes : Ezi ziingceba zeeseli ezibomvu zegazi. Zihlala zinembonakalo erhabaxa nephukileyo, kodwa zinokuba nasiphi na isimo.
• Ii-spherocytes: Ziyi-spherical. Njengebhola encinci.

Ngalunye lwezi ntlobo lunokunxulunyaniswa neemeko ezithile zempilo.

Zithini iimpawu zale meko?

Iimpawu ze-``Poikilocytosis`` ziyahluka ngokuxhomekeke kwisizathu. Nangona kunjalo, iimpawu ezihlala zibonakala ziyafana nezo zibangelwa yi-anemia.

Nazi ezinye zeempawu ze-anemia:

• Ubuthathaka okanye ukudinwa kakhulu (ukuziva nje udiniwe).
• Ubunzima bokuphefumla (ukuphelelwa ngamandla) – ukuphefumla kancinci nokuba kukho imisebenzi emincinci.
• Ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo (arrhythmia).
• Ngamanye amaxesha uva isandi esithi "whooshing" ezindlebeni zakho (pulsatile tinnitus).
• Intloko ebuhlungu .
• Isiyezi .
• Ulusu oluphaphathekileyo .
• Iintlungu zesifuba .

Ukuba unenye okanye ngaphezulu kwezi mpawu, kungcono ukufuna ingcebiso kagqirha.

Kutheni oku kusenzeka? Zithini izizathu?

Izizathu zezi ntlobo zeeseli ezibomvu zegazi ezingaqhelekanga zinokwahlulwa zibe ziindidi ezimbini eziphambili: ezizuzwe njengelifa kunye nezifunyenweyo . Ezinye iimeko, ezifana neMyelodysplastic Syndrome, zinokubangela zombini ezi mpawu.

Iimeko Ezizuzwe Njengelifa

Kwiimeko ezininzi, izizathu zokuzalwa zibangelwa yimpazamo kulwazi lwemfuza (i-DNA) yokuba iseli ebomvu yegazi ifanele ukukhula, ukusebenza, nokusinda ngokufanelekileyo. Iiseli ezibomvu zegazi ezinezakhiwo ezingaqhelekanga ziyaqhekeka ngokukhawuleza ngaphambi kokuba umzimba ukwazi ukwenza iiseli ezintsha. Oku kubizwa ngokuba yi -hemolytic anemia .

Ezinye zeemeko zokuzalwa ezibangela `(iPoikilocytosis)`:

• `(I-Elliptocytosis Yelifa)`
• `(I-Spherocytosis Yelifa)`
• `(Isifo sikaMcLeod)`
• `(Ukungabikho kwePyruvate Kinase)`
• `(Isifo seSickle Cell)` (Isifo seSickle Cell)`
• `(Thalassemia)`

Ezi zizinto ezidla ngokudluliselwa kwizizukulwana ngezizukulwana.

Iimeko ezifunyenweyo

Ekuhambeni kwexesha, ezinye iimeko zonyango zinokubangela ukuba imo yeeseli ezibomvu zegazi itshintshe. Umzekelo, ukuba umzimba awufumani izakhamzimba ezaneleyo ezifunekayo ukuze wenze iiseli ezibomvu zegazi ezisempilweni, ezifana ne -vitamin B12, i-folate, kunye ne-iron, kukho i-anemia eyahlukeneyo. I-Poikilocytosis luphawu oluqhelekileyo lwale ngxaki yokutya. Ingabangelwa zizifo, ezifana neminye imihlaza, eziphazamisa ukuveliswa kweeseli ezibomvu zegazi.

Ezinye zeemeko zamva ezibangela `(iPoikilocytosis)` zezi:

• I-Autoimmune Hemolytic Anemia
• Ukutsha (ukuba kukhulu)
• `(Isifo seCeliac)`
• Iintsholongwane ezahlukeneyo
• I-anemia yokunqongophala kwe-iron
• Isifo sezintso
• I-Leukemia (umhlaza wegazi)
• Isifo sesibindi
• I-Megaloblastic anemia (ngenxa ye-vitamin B12 okanye ukungabikho kwe-folate)
• `(I-Myelofibrosis)`
• Ityhefu (umz. ilothe)
• Ukusabela xa utofelwe igazi
• Ukusabela kwi-splenectomy
• Ukuluma kwenyoka

Zeziphi iingxaki ezinokubangela oku?

Iimeko ezininzi ezibangela i-poikilocytosis zinokulawulwa ngonyango, kwaye ezinye zinokunyangwa ngokupheleleyo. Nangona kunjalo, ukuba azinyangwa, ezinye iimeko zinokuba zimbi kakhulu kwaye zibeke ubomi esichengeni. Umzekelo, ukuba une-anemia, unokuziva udiniwe kangangokuba awukwazi ukwenza imisebenzi yakho yemihla ngemihla. Ukuba ulahlekelwa ziiseli zegazi ezibomvu ezisempilweni ngokwaneleyo ngokuhamba kwexesha, oku kunokukhokelela kwiimeko ezifana nokungasebenzi kakuhle kwamalungu omzimba .

Ingakumbi kubantwana abancinci, ukuba kukho i-anemia enganyangwanga, inokuchaphazela ukukhula kwabo nophuhliso lwabo.

Ngoko ke, xa ugqirha wakho efumanise unobangela wePoikilocytosis yakho, uya kunika unyango olufunekayo ukuthintela iingxaki ezinje ngezi.

Uyixilonga njani le nto kanye? (Uxilongo)

Uvavanyo oluphambili ugqirha anokulusebenzisa ukufumanisa i-poikilocytosis yi -peripheral blood smear (PBS) . Oku kubandakanya ingcali yelabhoratri ethatha ithontsi lesampulu yegazi lakho aze alijonge phantsi kwe-microscope. Emva koko banokubona ukuba zingaphi iiseli zakho ezibomvu zegazi ezimile ngendlela engaqhelekanga kunye nokuba ziluhlobo luni lwemilo yazo.

Ezinye iintlobo zeeseli zixhaphake kakhulu kwiimeko ezithile zesifo. Nangona kunjalo, nokuba kwimeko yesifo esifanayo, kunokubakho iintlobo ezahlukeneyo zeeseli. Umzekelo, kwiimeko ezifana ne-`(Hemolytic Anemia)`, `(Megaloblastic Anemia)`, `(Myelofibrosis)`, `(Thalassemia)`, iintlobo ezininzi zeeseli ezingaqhelekanga zinokubonwa.

Oogqirha bakho banokufuna ukwenza ezinye iimvavanyo ukuze bafumane ukuba yintoni kanye kanye ebangela i-poikilocytosis yakho.

Uvavanyo olongezelelweyo lokufumana unobangela we-`(Poikilocytosis)`

Ukubalwa kwegazi okupheleleyo (i-CBC) kudla ngokwenziwa kunye ne-PBS. I-CBC inokubonelela ngolwazi oluninzi malunga neeseli ezisegazini lakho, kubandakanya amanqanaba kunye nobukhulu bazo. Amanye amaxabiso kwi-CBC anokubonelela ngolwazi oluthe kratya malunga neeseli ezibomvu zegazi, ezinokunceda ekufumaneni unobangela wePoikilocytosis. La maxabiso aquka:

• `Umlinganiselo weCorpuscular Volume (MCV)` : Ubungakanani obuqhelekileyo beeseli zakho ezibomvu zegazi.
• `I-Mean Corpuscular Hemoglobin (MCH)` : Umyinge we-hemoglobin kwiiseli zakho ezibomvu zegazi.
• ``Umlinganiselo weHemoglobin yeCorpuscular (MCHC)'': Ixabiso eliphakathi loxinzelelo lwe-hemoglobin kwiiseli zakho ezibomvu zegazi.
• `Ububanzi boSasazo lweeSeli eziBomvu (RDW)` : Indlela iiseli zakho ezibomvu zegazi ezahluka ngayo ngobukhulu.

Ukongeza, ugqirha wakho unokujonga amanqanaba akho e-vitamin B12, i-folate, kunye ne-iron, kwaye unokuyalela uvavanyo lokusebenza kwesibindi.

Zithini iindlela zonyango zoku?

Unyango luxhomekeke kwisizathu se-poikilocytosis yakho kunye nokuba iimpawu zakho zinzima kangakanani.

Cinga ukuba ukuba unobangela wale meko kukungabikho kwesondlo (umz. i-iron, ukunqongophala kwe-vitamin B12), ukuthatha izongezo zesondlo ezifanelekileyo, okanye ukutshintshela ekutyeni okutyebileyo kwi-vitamin B12 okanye i-folate, kunokuyisombulula le meko `(Poikilocytosis)`.

Iimeko ezininzi zokuzalwa nazo zifuna ukubekwa esweni ngononophelo . Usenokufuna utofelo-gazi rhoqo ukuqinisekisa ukuba uneeseli zegazi ezibomvu ezaneleyo ezisempilweni. Okanye unokufuna unyango kuphela ngokusekelwe ekubeni unazo na iimpawu.

Ngaba le meko ingathintelwa?

Asinakuthintela izizathu zokuzalwa ze-"Poikilocytosis." Nangona kunjalo, singayinciphisa ingozi yezinye izizathu eziqala kamva.

Enye yezona ndlela zibalaseleyo zokunyamekela iiseli zakho ezibomvu zegazi kukufumana izondlo ezifunekayo emzimbeni wakho ukuze uzivelise. Qinisekisa ukuba ufumana iivithamini ze-B ezaneleyo, i-folate, kunye ne-iron . Ezi zizithako ezibalulekileyo umzimba wakho ozidingayo ukuze wenze iiseli ezibomvu zegazi ezisempilweni. Ikwanceda ekunciphiseni ubuninzi botywala obuselayo . Utywala obuninzi bunokwenza kube nzima emzimbeni wakho ukufunxa ezi zondlo.

Liza kuba njani ikamva? (Imbono)

Ngokubanzi, ukuba unobangela we-`(Poikilocytosis)` yimeko eqala kamva, i-prognosis idla ngokuba ntle. Kwimeko yezizathu zokuzalwa, i-prognosis iyahluka ngokuxhomekeke kwimeko esisiseko. Umzekelo, nangona ixesha lokuphila kwabantu abane-`(Sickle Cell Disease)` lithathwa njengelifutshane, unyango olutsha ngoku lwenze ukuba kube nokwenzeka ukuphila iminyaka engaphezu kwama-50 ngelixa kulawula iimpawu.

Ufanele uye nini kugqirha?

Ukuba uneempawu ze-anemia (izinto esithethe ngazo ngaphambili, njengokudinwa nobuthathaka), qiniseka ukuba ubonana nogqirha.

Nokuba uzive uphilile kwaye ungenazo iimpawu, kubalulekile ukuba uhlolwe rhoqo ngonyaka. Ugqirha wakho angajonga neeseli zakho zegazi. Uvavanyo olulula lwegazi, olufana nokubalwa kwegazi elipheleleyo (i-CBC), lunokunceda ekufumaneni nasekunyangeni iingxaki zempilo ngaphambi kokuba zibe nkulu.

Ingaba le "Poikilocytosis" yimeko enzulu?

`(Poikilocytosis)` ngokwayo ayisiyongxaki. Nangona kunjalo, ayisiyongxaki.Inokuba luphawu lwengxaki yempilo engaphantsi enokubangela iingxaki ukuba ayinyangwa. Ke ngoko, kubalulekile ukuqonda kakuhle ukuba yintoni ebangela `(Poikilocytosis)` kwaye ufune unyango ukuba kuyimfuneko.

I-Poikilocytosis isenokuvakala ngathi yimeko enzima, kodwa akunjalo. Yinto nje ebonakaliswa ziiseli zakho ezibomvu zegazi ezisetyenziswa ngoogqirha ukuvavanya impilo yakho. Ukuba ufumanisa ukuba iiseli zakho ezibomvu zegazi aziqhelekanga, ungathandabuzi ukubuza ugqirha wakho ngayo. Angakuxelela ukuba iyayichaphazela na impilo yakho, kwaye ukuba kunjalo, into onokuyenza ukuphelisa le meko okanye ukulawula imeko engaphantsi kwayo.

Izinto ezibalulekileyo ekufuneka sizikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngoko ke, amanqaku aphambili ekufuneka uwakhumbule kwinto esithethe ngayo zezi:

• I-Poikilocytosis iyenzeka xa ngaphezulu kwe-10% yeeseli zakho ezibomvu zegazi zimile ngendlela engaqhelekanga.
• Esi asisosifo, kodwa sisenokuba luphawu lwemeko ethile efihlakeleyo.
• Iimpawu ze-anemia (ukudinwa, ubuthathaka, ukuphaphatheka) nazo zinokubonakala kule meko.
• Izizathu zinokuba zizinto ezizalwa nazo okanye ezifunyenweyo (ukungondleki kakuhle, izifo ezithile).
• Oku kunokufunyaniswa ngovavanyo lwegazi olulula (`PBS`, `CBC`).
• Unyango luxhomekeke kwisizathu, kodwa lunokulawulwa rhoqo.
• Ukutya okunempilo kunokunceda ukuthintela ezinye zezizathu zokuba isifo siqale kamva.
• Ukuba uneempawu okanye unamathandabuzo malunga noku, kungcono ukubona ugqirha ukuze akunike ingcebiso.

Ngoko ke, ndiyathemba ukuba olu lwazi luluncedo kuwe. Hlala usempilweni!

I- Poikilocytosis, Iiseli zegazi ezibomvu, Imilo yeeseli zegazi, i-Anemia, Uvavanyo lwegazi, Impilo, i-Anemia, Iiseli zegazi ezibomvu, Uvavanyo lwegazi