Ngamanye amaxesha izihlunu zethu zivakala ngathi azinabomi, akunjalo? Iinkophe zethu ziyagoba, sinengxaki yokuthetha nokuginya, kwaye amalungu ethu aziva engenamandla. Namhlanje sithetha ngonyango olukhethekileyo olunyanga imeko ebizwa ngokuba yiMyasthenia Gravis, eneempawu ezifana nezi. Elo yeza yiPyridostigmine.
Yintoni iPyridostigmine?
Ngamafutshane, iPyridostigmine liyeza elinceda izihlunu zakho ziphinde zifumane amandla alahlekileyo. Imithambo-luvo kunye nezihlunu zomzimba wethu zinxibelelana ngekhemikhali. Kwimeko ye-'Myasthenia Gravis', olu nxibelelwano luyaphazamiseka. I-Pyridostigmine isebenza ngokoyisa olo phazamiseko kwaye ibuyisele unxibelelwano phakathi kwemithambo-luvo kunye nezihlunu.
Ugqirha wakho angakunika eli yeza phantsi kwamagama eempawu ezifana neMestinon okanye iMestinon Timespan. Igama elithi 'Timespan' okanye elithi 'extended-release' libhekisa kuhlobo olungena emzimbeni kancinci kwaye luhlale lusebenza ixesha elide.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Kulungile, ngaphambi kokuba uqale eli yeza, kubaluleke kakhulu ukuba ugqirha wakho ayazi kakuhle imeko yakho yempilo. Ukuba unayo nayiphi na kwezi meko zonyango zingezantsi, qiniseka ukuba umxelele ngayo.
| Imeko yezonyango/ezinye izinto | Kutheni ufanele uxelele? |
|---|---|
| Isifuba | I-Pyridostigmine inokunciphisa iindlela zomoya kwaye yonyuse ubunzima bokuphefumla. |
| Isifo sentliziyo okanye ukubetha kwentliziyo kancinci | Eli yeza linokuthi linciphise isantya sentliziyo ngakumbi. |
| Ubunzima okanye ukuvaleka komchamo | Le meko isenokuba mandundu. |
| Izilonda zesisu okanye ukuvaleka kwamathumbu | Iintlungu zesisu kunye nezinye iingxaki zesisu zinokwanda. |
| Isifo sezintso | Ekubeni iyeza lisuswa emzimbeni zizintso, kunokufuneka ukuba umlinganiselo walo ulungiswe. |
| Izifo zesisu (umz. i-Peritonitis) | Iimpawu zinokuba zingabonakali kangako kwaye ukuxilongwa kunokuba nzima. |
| Ukukhulelwa okanye ukuzama ukukhulelwa | Ugqirha uza kugqiba ukuba umntwana uchaphazelekile na. |
| Ukuncancisa | Kubalulekile ukuqwalasela ukuba ingaba iyeza lidluliselwa ebantwaneni ngobisi lwebele. |
| Ukunganyamezelani kwamanye amayeza, ukutya okanye izinto | Oku kubalulekile ukuvavanya umngcipheko wokuba ne-aleji kwiyeza. |
Ndingayisebenzisa njani le yeza?
Khumbula la manqaku xa usebenzisa eli yeza:
- Ginya le pilisi yonke ngeglasi yamanzi.
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ipilisi, ingakumbi ukuba iluhlobo 'lokukhululwa ixesha elide' (iTimespan), kuba oku kunokubangela ukuba iyeza lingene emzimbeni ngokukhawuleza kwaye libangele iziphumo ebezingalindelekanga.
- Sela idosi echanekileyo, kanye njengoko ugqirha wakho ekuyalele. Ugqirha wakho uza kukuxelela ukuba kangaphi ngosuku kwaye uthabathe malini.
- Ungaze uyeke ukuthatha amayeza akho ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela ukuba iimpawu (umz., ubunzima bokuginya, ubunzima bokuphefumla) zibe mandundu ngequbuliso.
- Ukuba eli yeza linikwa abantwana, kufuneka unonophelo olukhethekileyo kwaye kufuneka lenziwe kuphela ngokweengcebiso zonyango.
Kubalulekile: Ukuba ucinga ukuba uthathe ngaphezu kwedosi ecetyiswayo, fowunela ugqirha wakho ngoko nangoko.Fowunela iZiko loLwazi lweTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) yesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Thatha idosi ephosiweyo ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kuza kufuneka uthathe idosi elandelayo, yitsibe idosi ephosiweyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Musa ukuthatha idosi ephindwe kabini nangasiphi na isizathu!
Ezinye izinto ezinokusebenzisana nale mithi
Kubaluleke kakhulu ukuxelela ugqirha wakho malunga nayo yonke imithi, iivithamini, kunye nesondlo osithathayo, njengoko iPyridostigmine inokunxibelelana namanye amayeza.
| Uhlobo lwengozi | Imizekelo (iintlobo zamayeza) |
|---|---|
| Musa ukuthatha iPyridostigmine kunye nale yeza. | |
| Ngenxa yokuba izenzo ziyafana, iziphumo ebezingalindelekanga zinokwanda. | Amanye amayeza e-myasthenia gravis (umz. i-neostigmine), i-Quinine. |
| Nceda wazise ugqirha wakho kuba oku kusenokuchaphazela amayeza akho. | |
| I-Pyridostigmine inokunciphisa okanye yonyuse ukusebenza kwayo okanye ibangele iziphumo ebezingalindelekanga. | i-atropine, i-bethanechol, i-disopyramide, i-edrophonium, i-guanethidine, i-mecamylamine, kunye namanye amayeza alawula iintlungu zezihlunu okanye zemithambo-luvo. |
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho ngayo nayiphi na into oyithathayo.
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
- Bona ugqirha wakho ngexesha elicwangcisiweyo ukuze ujonge imeko yakho. Ukuba iimpawu zakho ziyaqhubeka okanye ziya zisiba mandundu, xelela ugqirha wakho.
- Kubaluleke kakhulu ukuba nesazisi sezonyango esichaza ukuba uneMyasthenia Gravis kunye namayeza owasebenzisayo kunye nemilinganiselo yawo. Oku kunokuba luncedo kakhulu xa kukho imeko engxamisekileyo.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, iPyridostigmine inokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Makhe sijonge ukuba zeziphi ezi.
| Imiphumela | Kwenziwe ntoni |
|---|---|
| Ukuba kukho nayiphi na kwezi zinto, xelela ugqirha wakho ngoko nangoko. | |
| Iimpendulo ze-allergy (ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso/imilebe/ulwimi) | Funa ingcebiso yezonyango ngoko nangoko. |
| Ubunzima bokuphefumla | |
| Utshintsho lombono | |
| Iintlungu ezinkulu zemisipha, ukuqaqamba, okanye ukuqhwalela | |
| Ukubetha kwentliziyo okucothayo kakhulu okanye okungaqhelekanga | |
| Intlungu ebuhlungu yesisu, ukuhlanza | |
| Ukudinwa okanye ubuthathaka obungaqhelekanga | |
| Ezi azinabungozi, kodwa ukuba ziyaqhubeka, xelela ugqirha wakho. | |
| Urhudo (ingakumbi ekuqaleni konyango) | Ukuba imeko iyaqhubeka, yazisa ugqirha. |
| Ukutyiwa kakhulu ngamathe | |
| Ukubila okwandileyo, isicaphucaphu | |
Ufanele uwagcine njani amayeza akho?
- Yigcine kwindawo ekhuselekileyo kude nabantwana.
- Gcina kubushushu begumbi (phakathi kwe-15-30 Celsius). Khusela kubushushu obugqithisileyo okanye kubanda.
- Khusela ekufumeni nasekukhanyeni kwelanga ngqo. Gcina ibhotile yamayeza ivaliwe kakuhle.
- Lahla amayeza aphelelwe lixesha ngaphandle kokuwasebenzisa.
Umyalezo Wokuya Ekhaya
- I-Pyridostigmine liyeza elisetyenziselwa ukunyanga isifo sobuthathaka bemisipha iMyasthenia Gravis.
- Ngaphambi kokuba uqale eli yeza, xelela ugqirha wakho ngazo zonke ezinye iimeko zempilo onazo (ingakumbi isifuba, isifo sentliziyo, isifo sezintso).
- Ginya ipilisi yonke, ungakhange uyiqhekeze okanye uyityumze. Yisele ngexesha elimiselweyo.
- Musa ukuyeka ukuthatha amayeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, ezinje ngobunzima bokuphefumla, iintlungu eziqatha zemisipha, okanye ukubetha kwentliziyo kancinci, qhagamshelana nogqirha wakho ngoko nangoko.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo. Oku kubaluleke kakhulu kukhuseleko lwakho.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Isetyenziselwa ntoni iPyridostigmine / Mestinon?
Le yipilisi ebaluleke kakhulu neyintloko enikwa isifo esibi se-neuromuscular esibizwa ngokuba yi-'Myasthenia Gravis'! Xa imiqondiso evela engqondweni yethu ingasafikeleli kwimisipha, imisipha yethu iyafa (asikwazi ukuvula amehlo ethu, ukuthetha, okanye ukuhamba). Into eyenziwa yile pilisi kukubuyisela amandla ezo zihlunu zilahlekayo nokubuyisela isigulana kwimeko yesiqhelo.
💬 Eli yeza (iPyridostigmine / iMestinon) lizivuselela njani izihlunu?
Umyalezo oya kwisihlunu uthunyelwa usuka engqondweni yethu ngemithambo-luvo yikhemikhali ebizwa ngokuba yi-'Acetylcholine'. Kodwa kwizigulane ezineMyasthenia, ezi zitshatyalaliswa ngokukhawuleza (yi-enzyme yeCholinesterase). Emva kokuthatha eli yeza, i-enzyme etshabalalisayo iyavalwa (i-Cholinesterase inhibitor), kwaye i-acetylcholine engaphezulu ivunyelwe ukuba iqokelelene kufutshane nezihlunu. Emva koko izihlunu zinokusebenza/zinciphe ngokuqhelekileyo/ziqine kwakhona.
💬 Zeziphi iziphumo ebezingalindelekanga ezicaphukisayo ezinokubakho xa usebenzisa eli yeza?
Oku akugcini nje ngokuvuselela izihlunu, kodwa kwandisa kakhulu ukusebenza kwamalungu angaphakathi afana namathumbu/isinyi! Ngoko ke, ukusela oku ngokuqinisekileyo kunokubangela iziphumo ebezingalindelekanga ezicaphukisayo ezifana 'norhudo olukhulu, iintlungu zesisu ezinzima, ukuvuza/ukukrazuka emlonyeni/emehlweni, kunye nokuchama rhoqo'. (Kwakhona, ukuba idosi inyusiwe, izihlunu zinokuwa/zingasebenzi!)
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