Ukuba wena okanye umntu kusapho lwakho unesifo sikaParkinson, ugqirha wakho usenokuba uninike uhlobo olutsha lwamayeza. Lubizwa ngokuba yi-selegiline, ithebhulethi enyibilikayo elulwimini. Yahlukile kancinci kwiipilisi oqhele ukuziginya ngamanzi. Ngoko ke namhlanje, masithethe ngokuba yintoni kanye kanye le mayeza, indlela yokuwasebenzisa, kunye namanyathelo akhethekileyo omawuwathathe xa uwasebenzisa.
Lithini eli yeza libizwa ngokuba yiSelegiline?
Ngamafutshane, iSelegiline liyeza elisetyenziselwa ukulawula iimpawu zesifo sikaParkinson. Lidla ngokunikwa abantu abasebenzisa iLevodopa. Isifo sikaParkinson senzeka xa kukho ukwehla kwe-dopamine yekhemikhali engqondweni yethu. Le dopamine inceda ukulawula iintshukumo zomzimba wethu kunye nokulungelelana kwazo. Ngoko ke, into eyenziwa yile pilisi yeSelegiline kukunyusa inqanaba le-dopamine engqondweni. Emva koko, iimpawu zesifo sikaParkinson ezifana nokuqina kunye nokungcangcazela ziyehla kancinci kancinci. Eli yeza likwiqela lamayeza abizwa ngokuba yi-MAOIs.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ngaphambi kokuba akunike iSelegiline, ugqirha wakho uza kukubuza imibuzo ethile. Ukuba unayo nayiphi na kwezi meko zingezantsi, ngokuqinisekileyo kufuneka umxelele ugqirha wakho .
- Ukuba une-high blood pressure.
- Ukuba unesifo sesibindi.
- Ukuba uxinzelelo lwegazi luphantsi.
- Ukuba une-narcolepsy (imeko ebangela ukozela okungalawulekiyo emini).
- Ukuba unesifo semfuza esibizwa ngokuba yiPhenylketonuria (PKU).
- Ukuba une-sleep apnea.
- Ukuba une-allergy kwiSelegiline okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe okanye uzama ukukhulelwa.
- Ukuba ungumama oncancisayo.
Ndingayisebenzisa njani kanye kanye le pilisi?
Indlela esetyenziswa ngayo le nto yahlukile kancinci, ngoko ke nika ingqalelo.
1. Yisele kusasa: Eli yeza lidla ngokuselwa kusasa. Lisele ngexesha elifanelekileyo njengoko ugqirha wakho ekuyalele.
2. Indlela yokususa ithebhulethi: Musa ukuyikhupha ithebhulethi ngokucinezela ifoyile yealuminiyam kwithebhulethi. Ukwenza njalo kunokubangela ukuba ithebhulethi idilike. Endaweni yoko, yitsale kancinci ifoyile ekhoneni uze uyisuse ngononophelo ithebhulethi ngezandla ezomileyo .
3. Yigcine elulwimini lwakho: Wakuba nje usele ipilisi, yigcine elulwimini lwakho. Iya kunyibilika yodwa kwimizuzwana embalwa. Musa ukuyiginya ngamanzi.
4. Linda imizuzu emi-5 ngaphambi kokutya: Emva kokuba ipilisi inyibilikile, musa ukutya okanye ukusela nantoni na kangangemizuzu emi-5 .
5.Yithathe ngexesha: Thatha amayeza kanye njengoko ugqirha wakho ekuxelele, ngexesha elifanelekileyo. Ungaze uthathe ngaphezu komlinganiselo omiselweyo.
6. Musa ukuyeka ngequbuliso: Kuphephe ukuyeka eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
Okubaluleke kakhulu: Eli yeza limiselwe wena kuphela. Ungaze ulinike omnye umntu.
Kuthekani ukuba ndisebenzisa i-overdose?
Ukuba ucinga ukuba uthathe ngaphezu komlinganiselo omiselweyo, fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke ngoko nangoko. Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) kwisibhedlele esikufutshane.
Ezinye izinto ezinokusebenzisana nale mithi (Intsebenziswano)
I-Selegiline liyeza elinokunxibelelana namanye amayeza nokutya. Ngoko ke, kubalulekile ukuxelela ugqirha wakho ukuba usebenzisa amanye amayeza.
| Musa ukuthatha iSelegiline kunye nale yeza konke konke! | |
|---|---|
| I-Atomoxetine | Izithomalalisi zentlungu ezifana neMeperidine, iMethadone, neTramadol |
| I-Cyclobenzaprine (isiphumzi semisipha) | I-Rasagiline, i-Safinamide (ezinye iziyobisi zesifo sikaParkinson) |
| I-Dextromethorphan (equlethwe kwiisiraphu zokukhwehlela) | Amayeza okuvuselela ukuphazamiseka kwengqondo |
| Ezinye ii-MAOI ezifana neMarplan, iNardil, iParnate | I-St. John's Wort (amayeza esintu) |
| I-Viloxazine | Amanye amayeza aqulethe iSelegiline, njenge-Emsam okanye i-Eldepryl |
| I-Selegiline inokuthi isebenzise ezi zinto, ngoko ke lumka. | |
|---|---|
| Amanye amayeza eengqondo ezifana nokudakumba kunye nokuxhalaba | Amayeza anjengePhenylephrine kunye nePseudoephedrine okuthintela ukuxinana kwempumlo |
| Amayeza afana neCarbamazepine, iPhenobarbital, iPhenytoin, asetyenziselwa isifo sokuwa (i-fits) | I-Metoclopramide (iyeza lokulwa nokugabha) |
| I-Ephedrine, i-Epinephrine, i-Norepinephrine | Ii-antibiotics ezifana neRifampin kunye neNafcillin |
| Ezinye iintlungu eziqatha ezinamandla | Ezinye izinto ezikhuthazayo ezisetyenziswa ukuze wehlise umzimba okanye uhlale uphaphile |
Olu luhlu aluphelelanga. Ngoko ke xelela ugqirha wakho ngazo zonke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu). Mxelele nokuba uyatshaya okanye usela utywala.
Izinto ekufuneka ziqwalaselwe xa usebenzisa iyeza
Ingqwalasela ekhethekileyo ekutyeni okuqulethe iTyramine
Oku kubaluleke kakhulu. Ukuba uthatha iSelegiline kwaye utya ukutya okune-tyramine eninzi, unokufumana ukunyuka ngequbuliso koxinzelelo lwegazi, iintloko ezibuhlungu, kunye nokubetha kwentliziyo okungaqhelekanga. Ngoko ke, kuphephe okanye unciphise ukutya okulandelayo:
- Itshizi ezigciniweyo
- Inyama neentlanzi ezigciniweyo, ezitshayiweyo, ezifakwe i-pickled (umz. iisoseji, i-salami)
- Iintlobo zeBhiya kunye neAle
- Iwayini (ingakumbi iwayini ebomvu)
- I-avokhado, ibhanana, umkhiwane, iirasentyisi
- Isosi yesoya, isuphu yemiso
- Isiqhamo esivuthiweyo kakhulu
Cela ugqirha wakho uluhlu olupheleleyo lwazo.
Amanye amanqaku abalulekileyo
- Ukozela kunye nesiyezi:Eli yeza lingakwenza uzive ulele okanye unesizungu. Ngoko ke, musa ukuqhuba okanye ukusebenzisa oomatshini ude wazi ukuba eli yeza likuchaphazela njani. Musa ukuma okanye ukuhlala ngequbuliso. Oku kunokunciphisa umngcipheko wokuwa nokuwa, ingakumbi ukuba sele ukhulile.
- Ukulala ngequbuliso: Abanye abantu banokulala ngequbuliso ngaphandle kwesilumkiso ngelixa besebenzisa eli yeza. Oku kunokwenzeka ngelixa beqhuba okanye bethetha. Ukuba oku kuyenzeka kuwe, xelela ugqirha wakho ngoko nangoko.
- Iminqweno engaqhelekanga: Ngelixa besebenzisa eli yeza, abanye abantu banokuba neminqweno enamandla yokungcakaza, ukulala ngesondo, ukutya kakhulu, okanye ukuchitha imali ngeendlela ababengenakuzenza ngokuqhelekileyo. Ukuba ufumana nayiphi na kwezi ndlela zokuziphatha ezingaqhelekanga, musa ukuba neentloni kwaye xelela ugqirha wakho.
- Umlomo owomileyo: Umlomo owomileyo uxhaphakile. Ungawulawula lo mbandela ngokuhlafuna itshungama engenaswekile nokusela amanzi amaninzi.
- Ukukhwehlela, umkhuhlane: Musa ukuthatha amayeza akho okukhwehlela, umkhuhlane, okanye i-allergies ngaphandle kokubonisana nogqirha wakho.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
| Ukuba ufumana ezi mpawu, bonana nogqirha ngokukhawuleza. | |
|---|---|
| Ii-aleji | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Igazi elonyukayo | Ukuqala ngequbuliso kwentloko ebuhlungu, isicaphucaphu, ukuhlanza, ukuqina kwentamo, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo. |
| Uxinzelelo lwegazi oluphantsi | Ukudinwa, ukuquleka, ukubona izinto ezingaqondakaliyo. |
| Utshintsho lwengqondo kunye nokuziphatha | Ixhala, ukungazinzi, ukuphazamiseka, ukubona izinto ezingekhoyo, iingcinga zokuzibulala, ukudakumba. |
| Iintshukumo ezingalawulekiyo | Iintshukumo ezintsha okanye ezikhulayo ezingalawulekiyo zobuso, umlomo, okanye umzimba ongasentla. |
| Okunye | Ukulala ngexesha lokusebenza emini, ufumana iminqweno engaqhelekanga. |
| Ukuba ezi mpawu ziyaqhubeka okanye ziyakukhathaza, xelela ugqirha wakho. | |
| Ukudinwa, ukozela | Umlomo owomileyo |
| Intloko ebuhlungu, isicaphucaphu | Ukungalali |
| Intlungu okanye ubuhlungu apho ipilisi ibekwe khona (emlonyeni) | |
Umyalezo Wokuya Ekhaya
- I-Selegiline yipilisi enyibilika phantsi kolwimi. Musa ukuyiginya ngamanzi. Musa ukutya okanye ukusela nantoni na imizuzu emi-5 emva kokuba ipilisi inyibilikile.
- Usenokuba nefuthe elibi kakhulu ekutyeni okuneTyramine (itshizi endala, inyama, iwayini) ngelixa usebenzisa eli yeza. Ngoko ke, kuphephe ukutya okunjalo.
- Eli yeza linokubangela ukozela ngesiquphe kunye nesiyezi. Ngoko ke, lumka kakhulu xa uqhuba okanye usenza imisebenzi efuna ukugxininiswa.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu, ezifana nokuziphatha okungaqhelekanga (njengokungcakaza), iintloko ezibuhlungu kakhulu, okanye utshintsho lwengqondo, xelela ugqirha wakho ngoko nangoko.
- Kubaluleke kakhulu ukwazisa ugqirha wakho malunga namayeza onke owasebenzisayo kunye nayo yonke imeko yempilo onayo.
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