Ukuthimla rhoqo, impumlo evuzayo, kwaye ngamanye amaxesha kunzima ukuphefumla... Ziyacaphukisa kangakanani ezi zinto? Abantu abaninzi banesifo se -allergies kunye ne-asthma. Ngoko ke namhlanje siza kuthetha ngodidi olutsha lwamayeza asetyenziswa ukulawula ezi meko. La abizwa ngokuba yi-'Leukotriene Modifiers'.
Zithini iiLeukotriene Modifiers? Zisebenza njani?
Ngaphambi kokuba siqonde eli yeza, masifunde ngento encinci eyenzekayo emizimbeni yethu.
Ngamafutshane, xa into ethile esinayo i-allergen, oko kukuthi, i-allergen - umzekelo, uthuli, i-pollen - ingena emzimbeni wethu, inkqubo yethu yomzimba yokuzikhusela iyasabela kuyo. Njengenxalenye yale mpendulo, umzimba wethu uvelisa iikhemikhali ezibizwa ngokuba yi -'leukotrienes' .
Le khemikhali, ebizwa ngokuba yi-leukotriene, ibangela uninzi lweempawu zethu ze-allergy kunye ne-asthma . Oku kungenxa yokuba:
- Iindlela zomoya eziya emiphungeni ziyancitshiswa, nto leyo eyenza kube nzima ukuphefumla (ukufuthaniseka).
- I-mucus kunye nezinye izinto eziphumayo ziveliswa ngakumbi ngaphakathi kwimigudu yomoya.
- Izicubu zempumlo ziyadumba kwaye impumlo iyavaleka.
Ngoko ke, into eyenziwa yiLeukotriene Modifiers kukuthintela isenzo sekhemikhali ebizwa ngokuba yi-leukotriene. Ngokuchanekileyo, zithintela le khemikhali ukuba ingasebenzisani neeseli emzimbeni. Kufana nokuvala ucango. Kwaye oko kulawula ukwenzeka kwezo mpawu zicaphukisayo esithethe ngazo ngaphambili. Kodwa khumbula, ezi aziqhelekanga ukuba lunyango lokuqala.
Eli yeza linceda njani ukulawula iimpawu ze-allergy?
Ukuthimla, impumlo egobhozayo, impumlo egobhozayo, kunye nempumlo exineneyo ziimpawu eziqhelekileyo ze-allergies (i-allergy rhinitis). Ukongeza, amehlo arhawuzelelwayo, avuvukileyo, anamanzi (i-allergy conjunctivitis) kunye nomqala obuhlungu nazo zinokubakho. Abo bahlangabezana nezi meko bayazi ukuba kunzima kangakanani ukuphila nazo.
Izifundo zibonisa ukuba malunga ne-85% yabantu abane-asthma nabo baneempawu ze-allergy. Ukongeza, i-allergies ezinganyangwanga zinokubangela iingxaki ezifana ne-sinusitis, umphimbo obuhlungu rhoqo, ukukhwehlela, iingxaki zokulala , kunye nokungakwazi ukusebenza kakuhle esikolweni okanye emsebenzini.
Ii-Leukotriene modifiers, ezithintela ukusebenza kwe-leukotrienes, ziluncedo kakhulu ekulawuleni ukuthimla nokurhawuzelela okwenzeka kwizigaba zokuqala ze-allergies, kunye nokuxinana kweempumlo okwenzeka emva kwexesha elithile.
Ungayisebenzisa njani le yeza kwi-asthma?
La mayeza asetyenziswa kakhulu ekuthinteleni nasekulawuleni isifo sesifuba ixesha elide. Akwacetyiswa nasekuthinteleni isifo sesifuba esibangelwa kukuzilolonga.
Nangona kunjalo, oku kubaluleke kakhulu : Eli yeza alinakusetyenziswa lodwa ukulawula uhlaselo lwe-asthma olukhawulezileyo. Oku kuthetha ukuba ukuthatha eli yeza akuyi kunceda xa i-asthma inzima kakhulu kwaye unengxaki yokuphefumla. Ngamaxesha anjalo, kufuneka usebenzise i-inhaler esebenza ngokukhawuleza, ekhulula umkhuhlane. Eli yeza le-Leukotriene Modifier libalulekile ukugcina isifo silawulwa.
Zeziphi iiLeukotriene Modifiers ezisetyenziswa kakhulu eSri Lanka?
Nangona amayeza e-asthma afana ne-`zafirlukast (Accolate)` kunye ne-`zileuton (Zyflo)` eliqela eli, amayeza asetyenziswa kakhulu eSri Lanka, avunyiweyo kwi-rhinitis ye-allergy kunye ne-asthma, yi -`montelukast` . Usenokuba uyazi ngegama lophawu lwe-`Singulair`.
Nantsi indlela esebenza ngayo i-montelukast njengoko ifunyenwe kuphando:
| Uthelekiso | Iziphumo zeMontelukast |
|---|---|
| Nge-placebo (into engeyoyeza) | Ilawula iimpawu ngcono kune-placebo. |
| NgeLoratadine (efana neLoratadine - Claritin) | Ibonisa iziphumo eziphantse zifane nezo ze-loratadine. |
| Ngee-steroids ezifunxwayo ngeempumlo | Akukho siphumo sinamandla njenge-spray ye-steroid yempumlo. |
Ngoko ke, oogqirha badla ngokucebisa ukuba bazame i-intranasal steroid spray ngaphambi kokuba banike i-Leukotriene Modifier, njengoko imiphumo yayo inokuba namandla ngakumbi.
Ngaba kukho naziphi na iziphumo ebezingalindelekanga?
Njengakweyiphi na iyeza, abanye abantu banokufumana iziphumo ebezingalindelekanga. Ezona zixhaphakileyo ziquka:
- Uziva ngathi unomkhuhlane
- Intloko ebuhlungu
- Isisu esibuhlungu
- Isicaphucaphu okanye ukuhlanza
- Ukuxinana kwempumlo
Into ekufuneka uyilumkele ngokukodwa!
I-FDA ikhuphe isilumkiso malunga nomngcipheko weziphumo ebezingalindelekanga zempilo yengqondo ezibangelwa liyeza elithi `Montelukast`. Nangona ezi zinqabile kakhulu , kubalulekile ukuba uzazi.
Ukuba wena okanye umntwana wakho nifumana naziphi na ezi mpawu ngelixa nisela eli yeza, yekani ukulisela ngoko nangoko nize nazise ugqirha wenu:
- Ukungazoli, ukuphazamiseka
- Amaphupha angaqhelekanga okanye awoyikisayo
- Uxinzelelo
- Iingcinga zokuzibulala
Ukuba ubona into efana nale, musa ukulibazisa. Funa ingcebiso kagqirha ngoko nangoko.
Ngubani ongafanele asebenzise eli yeza?
- Abantwana abancinci: Ukhuseleko lwala mayeza e-asthma kwiintsana ezingaphantsi kweenyanga ezili-12 ubudala kunye ne-perennial allergy rhinitis kwiintsana ezingaphantsi kweenyanga ezi-6 ubudala alukaqinisekiswa. Ngoko ke, musa ukunika abantwana abancinci la mayeza ngaphandle kwengcebiso kagqirha.
- Oomama abakhulelweyo nabancancisayo: Ukuba ukhulelwe, uceba ukukhulelwa, okanye uncancisa, ngokuqinisekileyo kufuneka uthethe nogqirha wakho ngaphambi kokuba usebenzise eli yeza.
Eli yeza liza ngohlobo lweepilisi, iipilisi ezihlafunwayo, kunye neegranules. Kungathatha naphi na ukusuka kwiintsuku ezintathu ukuya kwiiveki ezimbini ukufumana inzuzo epheleleyo yeli yeza. Ngoko ke ungayeki ukulithatha kuba nje ungaziva ngcono kwiintsuku ezimbini okanye ezintathu. Lisebenzise lonke ixesha njengoko ugqirha wakho ekuyalele.
Umyalezo Wokuya Ekhaya
- IiLeukotriene Modifiers luhlobo lwamayeza asetyenziselwa ukunyanga i-allergies kunye ne-asthma ixesha elide.
- Ezi azinakusetyenziswa njengonyango olungxamisekileyo lokuhlaselwa sisifo sesifuba ngequbuliso.
- Iyeza elisetyenziswa kakhulu eSri Lanka yi
montelukast. - Ukuba ubona naluphi na utshintsho olungaqhelekanga (uxinzelelo, ukudakumba, amaphupha angaqhelekanga) ngelixa usebenzisa eli yeza, ingakumbi ngokwempilo yengqondo, xelela ugqirha wakho ngoko nangoko.
- Njengakweminye imithi, le mithi ifanele isetyenziswe kuphela phantsi kwengcebiso kagqirha. Ugqirha wakho uya kugqiba unyango olulungele wena.
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