Ukufakelwa amalungu omzimba kufana nobomi besibini, akunjalo? Ngokwenene ngummangaliso wezonyango. Nangona kunjalo, kukho ithuba elikhulu lokuba umzimba wakho uya kuyibona i-organ entsha (intliziyo, izintso, isibindi, okanye imiphunga) etyalwe ngale ndlela "njengeyangaphandle" kwaye iyihlasele. I-Tacrolimus liyeza elibaluleke kakhulu eliyekisa loo mpendulo (ukungavumi) kwaye lincede umzimba ukuba wamkele i-organ entsha njengenxalenye yayo. Ixhaphake kakhulu phantsi kwegama lophawu iPrograf. Ngoko ke, ukuba wena okanye umntu omaziyo unikwa le gonyo, kubaluleke kakhulu ukuba nolwazi olupheleleyo ngayo.
Kwenzeka ntoni ngokwenene kwiTacrolimus?
Ngamafutshane, iTacrolimus sisixhobo sokuthintela amajoni omzimba. Cinga ngomzimba wakho njengelizwe, kwaye inkqubo yakho yokuzikhusela komzimba ngumkhosi welo lizwe. Nantoni na evela ngaphandle - njengentsholongwane - ihlaselwa kwaye itshatyalaliswe ngulo mkhosi. Le yinto entle kakhulu.
Nangona kunjalo, isitho esitsha esisandul’ ukufakelwa sibonwa njengesitho "sangaphandle" ngumzimba. Ngoko ke, isitho somzimba (isitho somzimba) siqala ukuhlasela isitho esitsha nesixabisekileyo. Oku sikubiza ngokuba kukwaliwa sisitho. I-Tacrolimus isebenza ngokulawula kancinci umsebenzi wesitho sakho somzimba kwaye iyithintele ekuhlaseleni isitho esitsha. Ngale ndlela, isitho esitsha senziwe emzimbeni nakwindawo esiyifunayo ukuze sikhule kakuhle kwaye senze umsebenzi waso ngokufanelekileyo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqale i-tacrolimus, kubaluleke kakhulu ukuxelela ugqirha wakho ngembali yakho epheleleyo yempilo. Eli yeza linokuchaphazela iinkqubo ezininzi emzimbeni. Qiniseka ukuba uxelela ugqirha wakho malunga noku:
- Ezinye izifo onazo:
- Isifo seswekile okanye amanqanaba aphezulu eswekile egazini.
- Isifo sentliziyo okanye ukungasebenzi kakuhle kwesingqisho sentliziyo.
- Igazi elonyukayo.
- Isifo sezintso okanye sesibindi.
- Nasiphi na isifo esikhoyo ngoku (umkhuhlane, umkhuhlane, ukukhwehlela, njl.njl.).
- Ezinye iingxaki zomzimba ezibangelwa kukungasebenzi kakuhle.
- Ukukhulelwa nokuncancisa:
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa, kubalulekile ukuxelela ugqirha wakho ngale nto.
- Iingxaki zokunganyamezelani komzimba:
- Xelela ugqirha wakho ukuba une-allergies kwi-tacrolimus okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukugonywa:
- Ukuba usandul’ ukufumana ugonyo okanye ucwangciselwe ukulufumana kwixesha elizayo, sixelele ngalo.
Ukuxelela ugqirha wakho olu lwazi ngaphandle kokulifihla kubaluleke kakhulu kukhuseleko lwakho kunye nempumelelo yonyango lwakho.
Indlela yokunika ugonyo lweTacrolimus nezinye izinto
Eli asiloyeza onokulithatha ekhaya. I-Tacrolimus inikwa ngemithambo yegazi (IV). Inikwa esibhedlele okanye ekliniki ngugqirha okanye umongikazi oqeqeshiweyo. Ngoko ke akufuneki ukhathazeke ngokuphoswa yidosi.
Ukuba ucinga ukuba ngempazamo usele idosi engaphezulu, kuya kulawulwa ngabasebenzi besibhedlele. Ngaphandle koko, ukuba kukho ezinye iingxaki ezivelayo, kubalulekile ukwazisa ngokukhawuleza iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke okanye iYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
I-Tacrolimus liyeza elinokusebenzisana namanye amayeza amaninzi. Ngoko ke, kubalulekile ukwazisa ugqirha wakho malunga nawo onke amayeza owasebenzisayo (abhalwe ngabanye oogqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, iivithamini, amayeza esintu, kwaneemveliso zezityalo).
Masicacise oku ngakumbi ngezi theyibhile zingasezantsi.
| Ungaze usebenzise iTacrolimus ngezi zinto! | |
|---|---|
| I-Cidofovir, i-Cisapride | IMesoridazine, iMifepristone |
| I-Cyclosporine, iDronedarone | I-Pimozide, iSaquinavir |
| I-Fluconazole | I-Thioridazine, i-Ziprasidone |
| Ijusi yegrapefruit | Izitofu zokugonya iintsholongwane eziphilayo |
| Lumka kakhulu nangezi zinto. | |
|---|---|
| Amanye amayeza okubulala iintsholongwane | Ezifana neClarithromycin, iErythromycin, neRifampin. |
| Amayeza e-HIV okanye i-Hepatitis | Amayeza okulwa neentsholongwane. |
| Izinto ezilwa nokungunda | NjengeKetoconazole, iItraconazole, neVoriconazole. |
| Amayeza oxinzelelo lwegazi oluphezulu | Ezifana neDiltiazem, iNifedipine, iVerapamil. |
| Amayeza e-gastritis | Ezifana ne-Omeprazole, iLansoprazole, iFamotidine. |
| Iimveliso zezityalo | Izinto ezifana ne-St. John's wort. |
| Amanye amayeza | Utywala, iiSteroids (ezifana nePrednisone), iSirolimus, iiDiuretics. |
Izinto ekufuneka ziqwalaselwe ngexesha lonyango
- Zikhusele kwiintsholongwane: I-Tacrolimus yenza amasosha omzimba wakho abe buthathaka, ngoko ke unokufumana iintsholongwane ezingafunyanwa ngumntu oqhelekileyo. Ngoko ke, hlala kude neendawo ezinabantu abaninzi, hlala kude nabantu abagulayo, kwaye uhlambe izandla zakho rhoqo. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, iintlungu zomzimba, umphimbo obuhlungu, okanye ukukhwehlela, musa ukuzinyanga kwaye wazise ugqirha wakho ngoko nangoko.
- Ukuthintela ukukhulelwa: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza.Abafazi namadoda kufuneka basebenzise uhlobo lokuthintela ukukhulelwa olusebenza kakuhle kakhulu. Eli yeza linokulimaza kakhulu usana olusesibelekweni.
- Umngcipheko womhlaza: Ukusela la mayeza okunciphisa amasosha omzimba ixesha elide kunokunyusa kancinci umngcipheko wakho weentlobo ezithile zomhlaza, njengomhlaza wolusu kunye ne-lymphoma. Thetha nogqirha wakho ngale nto.
- Ukukhusela ilanga: Eli yeza lingenza ulusu lwakho lube buthathaka ngakumbi ekukhanyeni kwelanga. Ngoko ke, ukuba uza kuba selangeni, sebenzisa isithinteli selanga esifanelekileyo, nxiba umnqwazi, kwaye unxibe impahla egquma umzimba wakho.
- Amanqanaba eswekile egazini: Eli yeza lisenokunyusa amanqanaba eswekile egazini. Ukuba unesifo seswekile, jonga amanqanaba eswekile egazini lakho rhoqo.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengayo nayiphi na iyeza, iTacrolimus inokubangela iziphumo ebezingalindelekanga. Ezinye zezi ziyingozi kwaye kufuneka zixelwe ngoko nangoko.
| Imiphumela | Inkcazo |
|---|---|
| Izinto ekufuneka uzixelele ugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Iingxaki zentliziyo | Intlungu esifubeni, ubunzima bokuphefumla, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, isiyezi. |
| Ukwanda kweswekile egazini | Indlala eyanda ngokungaqhelekanga, unxano, ukuchama rhoqo, ukubona okufipheleyo. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu, usulelo lomchamo. |
| Impembelelo kwizintso | Ukuncipha kokuphuma komchamo okanye ubunzima bokuchama. |
| Iingxaki zenkqubo yemithambo-luvo | Intloko ebuhlungu kakhulu, ukuxhuzula, utshintsho lombono, utshintsho lokuziphatha, ukungaziva mnandi kwamalungu omzimba. |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki zenkqubo yokugaya ukutya | Intlungu yesisu, ukuqhina kwesisu, urhudo. |
| Ukungalali | Ingxaki yokulala. |
| Ukudumba komzimba (i-Edema) | Ukudumba kwezandla, iinyawo, amaqatha, okanye ukunyuka kobunzima ngequbuliso. |
Umyalezo Wokuya Ekhaya
- I-Tacrolimus liyeza elibaluleke kakhulu elinikezelwayo ukuthintela umzimba ukuba ungalamkeli ilungu emva kokufakelwa ilungu.
- Oku kunikwa esibhedlele kuphela, phantsi kweliso likagqirha.
- Kubalulekile ukuxelela ugqirha wakho malunga nawo onke amanye amayeza, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Njengoko inciphisa amajoni omzimba, lumka ngokukodwa ukuze uzikhusele kwiintsholongwane. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, yazisa ugqirha wakho ngoko nangoko.
- Abafazi namadoda kufuneka basebenzise ucwangciso-nzala olusebenzayo ngexesha lonyango.
- Ukuba kukho naziphi na iingxaki okanye amathandabuzo, thetha nogqirha wakho kwaye ulandele imiyalelo yakhe ngokuchanekileyo.
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