Ngaba nawe unevumba elibi leentlanzi? Masifunde ngeTrimethylaminuria (TMAU)!

Ngamanye amaxesha ebomini bethu, izinto ezingaqhelekanga ziyenzeka, akunjalo? Ngaba wakha weva ngemeko apho umzimba womntu, ukubila, umphefumlo, okanye umchamo unuka njengentlanzi ebolileyo? Kuvakala kungaqhelekanga, akunjalo? Kodwa, kukho imeko enjalo ngokwenene. Le yimeko esiza kuthetha ngayo namhlanje, iTrimethylaminuria, okanye `(TMAU)` ngamafutshane. Abanye abantu bayibiza ngokuba yi-`Fish Odor Syndrome``.

Yintoni i-trimethylaminuria (TMAU)?

Ngamafutshane, i-trimethylaminuria (TMAU) sisifo se-metabolic disorder . Ngoku usenokuba uzibuza ukuba yintoni isifo se-metabolic disorder. Ngaphakathi emizimbeni yethu, iinkqubo zeekhemikhali, okanye iinkqubo ze-metabolic , zenzeka ukuguqula ukutya esikutyayo kube ngamandla nokwenza izinto ezifunekayo emzimbeni wethu. Ii-enzymes emizimbeni yethu zinceda ezi nkqubo ukuba zenzeke ngokufanelekileyo. Ngoko ke, kule meko ibizwa ngokuba yi-trimethylaminuria, ngenxa yotshintsho kumsebenzi we-enzyme ethile, ezinye zeekhemikhali eziveliswa emzimbeni azinakwahlulwa ngokufanelekileyo. Yiyo loo nto ivumba elibi leentlanzi liphuma ekubileni, ekuphefumleni, ematheni, nakumchamo.

Usenokuba ukhe weva oogqirha bebiza le meko ngokuthi `(TMAU)` okanye `(Fish Odor Syndrome)`. Akukho nyango lupheleleyo lwale nto okwangoku . Kodwa, ungakhathazeki. Ungazinciphisa ezi mpawu ngokutshintsha into oyityayo noyiselayo, usebenzisa iisepha kunye ne-lotions ezithile, kunye nokulawula uxinzelelo lwakho.

Ziziphi iintlobo eziphambili ze-`(TMAU)`?

Kukho iintlobo ezimbini eziphambili ze-trimethylaminuria:

1. I-Trimethylaminuria ePhambili : Olu luhlobo lokuzalwa . Oku kuthetha ukuba le meko ibangelwa lutshintsho oluthile (`(uguquko lwezakhi zofuzo)`) kwiijini (`(iijini)`) ezizuzwe kumama nakutata.

2. I-Trimethylaminuria yesibini : Oku kwenzeka kamva ebomini . Eli vumba lifana nelentlanzi linokubangelwa ziimeko ezithile zonyango okanye izongezo zokutya.

Ixhaphake kangakanani le meko?

Enyanisweni, i-TMAU yimeko engaqhelekanga . Olunye uphando lubonisa ukuba ichaphazela umntu omnye kuphela kubantu abangama-200,000 ukuya kwisigidi esinye kwihlabathi liphela. Nangona kunjalo, kuthiwa abafazi banamathuba amancinci okuba nayo kunamadoda.

Nangona kunjalo, abanye abaphandi bakholelwa ukuba kusenokuba kukho abantu abaninzi abane `(TMAU)` kuluntu kunokuba ezi zibalo zibonisa. Kuba abantu abaninzi bacinga ukuba le yingxaki yokucoceka kwabo . Ngenxa yoko, abaxeleli mntu ngayo okanye baye kugqirha ngenxa yeentloni. Ngoko ke, abafumani kuxilongwa (`(Diagnosis)`).

Zithini iimpawu ze-trimethylaminuria?

Uphawu oluphambili nolucacileyo livumba elifana nelentlanzi elivela emzimbeni, emphefumlweni, nasekubileni . Eli vumba ngamanye amaxesha linokuba libi kangangokuba linokubangela isicaphucaphu. Kwabanye abantu, linokuhamba nomoya ombi (`(Halitosis)`) kunye nevumba elinamandla elivela kumchamo.

Ngamanye amaxesha, umntu one-`(TMAU)` uziva eli vumba kakhulu xa ebila okanye xa exinezelekile. Nangona kunjalo, kwabanye abantu, eli vumba linamandla kangangokuba nokuba baya kwigumbi abahlala kulo, bemi ngaphesheya kwekhawuntara evenkileni, okanye behleli kwelinye icala lebhasi okanye uloliwe, abanye basenokulivumba. Khawuthelekelele ukuba kunzima kangakanani oko.

Zithini izizathu ze-`(TMAU)`?

I-Trimethylaminuria yenzeka xa umsebenzi we-enzyme ebizwa ngokuba yi-`(FMO3)` emzimbeni wethu uphazamisekile. `(FMO3)` imele i-flavin- containing monooxygenase 3. Umsebenzi ophambili wale enzyme kukulawula ikhemikhali ebizwa ngokuba yi-`( Trimethylamine )` eveliswa emzimbeni wethu. Le trimethylamine yimbangela yelo vumba lentlanzi. Le trimethylamine iveliswa xa ukutya okuthile esikutyayo, umzekelo, intlanzi, iimbotyi, kunye namaqanda, kugaywa.

Okuqhele ukwenzeka kukuba: Xa i-trimethylamine iqokelelana emizimbeni yethu, i-enzyme `(FMO3)` iyafika ize iyiqhekeze, iyiguqule ibe yikhemikhali engenavumba. Emva koko, nangona idlula kwinkqubo yethu yokugaya iye egazini lethu, ayinuki.

Kodwa, kwenzeka ntoni ukuba loo enzyme `(FMO3)` ayisebenzi kakuhle? Loo trimethylamine ivumbayo iyaqokelelana emizimbeni yethu. Xa iqokelelana, ekugqibeleni iphuma ngokubila, umphefumlo, amathe, nomchamo, kwaye elo vumba lifana nelentlanzi liyaphuma. Uyaqonda?

Abantu abane -primary trimethylaminuria (`(Primary TMAU)`) bakhula nale meko kuba bafumana iikopi ezingaqhelekanga zezakhi zofuzo ezenza i-`(FMO3)` enzyme (`(Abnormal FMO3 genes)`) kumama notata wabo.

Kwi -trimethylaminuria yesibini (`(i-Secondary TMAU)`), i-enzyme yakho ye-`(FMO3)` ayikwazi ukuqhekeza i-trimethylamine ngesizathu esithile. Oku kunokubangelwa yile:

• Ukuba unesifo esithile, esifana nokungasebenzi kakuhle kwesibindi okanye i-viral hepatitis , oku kunokuphazamisana nomsebenzi we-enzyme kwaye kuyithintele ekuwohlokeni kwe-trimethylamine.
• Ukuba i-microbiome yamathumbu akho ayilungelelananga, nto leyo ethetha ukuba kukho ukungalingani phakathi kweebhaktheriya ezilungileyo nezimbi emathunjini akho, i-trimethylamine eninzi kakhulu inokuqokelelana. Emva koko i-enzyme (FMO3) ayinakukwazi ukususa lonke elo vumba.
• Ukuba uthatha izongezo ezine -choline okanye i-carnitine , ezi zondlo zinegalelo ekwakhiweni kwe-trimethylamine.

Zithini iingxaki zale meko?

Indlela imeko ebizwa ngokuba yi-trimethylaminuria echaphazela ngayo umgangatho wobomi bakho(`(Umgangatho wobomi)`) unokuba yingozi kakhulu. Uphando lubonisa ukuba abantu abanale meko badla ngokuphepha ubudlelwane, imisebenzi, kunye nemisebenzi yoluntu kuba besoyika ukuba abanye baya kuyiqaphela ivumba elibi. Ngenxa yoku, abantu abanale meko banokuba neengxaki ezahlukeneyo zempilo yengqondo. Umzekelo:

• Ixhala
• Uxinzelelo
• Ixhala kunye noloyiko olungenangqiqo (`(I-Paranoia)`)

Nangona kunqabile kakhulu, abanye abantu abane-TMAU baye baxelwa ukuba baneengcinga zokuzibulala (`(ukuziphatha kokuzibulala)`). Oku kubonisa indlela impembelelo yengqondo yale meko enokuba yingozi ngayo.

Ifunyaniswa njani i-trimethylaminuria?

Oogqirha baxilonga i-TMAU ngokulinganisa ubungakanani be-trimethylamine kumchamo wakho. Oku kudla ngokwenziwa ngovavanyo lomchamo . Ukongeza, ugqirha wakho unokucebisa uvavanyo lwemfuza ukuze abone ukuba unefomu yokuqala (oko kukuthi, yokuzalwa) okanye yesibini (oko kukuthi, efunyenweyo).

Ziziphi iindlela zonyango lwe-trimethylaminuria?

Ugqirha wakho unokucebisa izinto ezahlukeneyo ukunceda ukunciphisa iimpawu ze-TMAU.

• Ukutya: Kucetyiswa ukuba kupheliswe ukutya okuthile okwandisa imveliso yomzimba yekhemikhali ebangela esi sifo (TMAU).
• Iisepha kunye neeloshini ezikhethekileyo: Kucetyiswa ukuba kusetyenziswe iisepha kunye neeloshini ezikhethekileyo ezinceda ekunciphiseni ivumba leentlanzi eluswini.
• Amayeza: Ngamanye amaxesha amayeza anokunikwa.
• Inkxaso yempilo yengqondo: Ungacetyiswa nokuba ufumane iingcebiso zengqondo ukuze ukwazi ukumelana noxinzelelo olubangelwa yile meko.

Ziziphi iintlobo zokutya ekufuneka zisuswe?

Ukuba une-trimethylaminuria, oogqirha badla ngokukuxelela ukuba unciphise okanye uphephe ngokupheleleyo ukutya okulandelayo:

• Iintlanzi nezinye iintlobo zokutya kwaselwandle (ingakumbi iintlanzi zasemanzini anetyuwa)
• Amaqanda (ingakumbi amaqanda aqanda)
• Isibindi nezinye izitho zangaphakathi zesilwanyana
• Imifuno efana neesoya, iitshizi kunye neelentile
• Imifuno yeCruciferous efana nekhaphetshu, ibroccoli, ikholifulawa, kunye neBrussels sprouts
• Ipinati
• Ubisi kunye neemveliso zobisi (kwabanye)
• Ukutya kunye nezongezo zesondlo ezityebileyo kwi-choline kunye ne-L-carnitine

Kubalulekile: Asinguye wonke umntu omele ayeke konke oku kutya. Kungcono ukuthetha nogqirha okanye ingcali yesondlo ukuze ubone ukuba zeziphi ukutya ezikulungeleyo.

Ngawaphi amayeza anikwayo kwi-`(TMAU)`?

Ugqirha wakho angakunika amayeza afana nala ukunciphisa iimpawu zeTMAU:

• Ii-antibiotics kunye nee-probiotics : La mayeza anceda ekunciphiseni inani leebhaktheriya emathunjini akho, ngaloo ndlela enciphisa ukuveliswa kwe-trimethylamine.
• I-activated charcoal : Oku kufana nesiponji. Kufunxa i-trimethylamine emzimbeni kwaye kuyanceda ukuba ikhutshwe kwi-tube.
• Amayeza okudakumba kunye namayeza okulwa nokuxhalaba : La mayeza anikwa ukunyanga iingxaki zempilo yengqondo ezijongene nabanye abantu abane-TMAU.

Ugqirha wakho unokukuthumela kwinkxaso -mali yempilo yengqondo . Ukuthetha nogqirha wengqondo okanye umcebisi kubaluleke kakhulu ukuba unengxaki yokuzihlonipha kunye neengxaki zomfanekiso womzimba. Unyango lwengqondo lunokukunceda ufunde indlela yokujongana nemeko yakho kunye nokulawula uxinzelelo.

Yintoni enokulindelwa ngumntu one-trimethylaminuria?

I-Trimethylaminuria yimeko engapheliyo . Oku kuthetha ukuba ayinakunyangwa ngokupheleleyo okanye iphile yodwa. Nangona kunjalo, njengoko bekutshiwo ngaphambili, kukho unyango kunye nezinto onokuzenza ukunciphisa iimpawu ze-TMAU kunye nokunciphisa impembelelo yesi sifo ebomini bakho.

Ndingazinyamekela njani ?

Ukuzinyamekela kubaluleke kakhulu xa uhlala ne-TMAU. Nazi ezinye izinto ekufuneka uziqwalasele:

• Ucoceko lomntu : Ukusebenzisa isepha kunye neloshini ezinexabiso eliphantsi le-`(pH)` kunokunceda ukunciphisa ivumba lomzimba wakho. Buza ugqirha wakho ukuba leliphi ixabiso le-`(pH)` elifanelekileyo kuwe kunye nemveliso efanelekileyo.
• Lumka ngento oyityayo : Ukutya okuninzi kunokwenza i-trimethylaminuria ibe mandundu. Thetha nengcali yesondlo ukuze ucwangcise ukutya kwakho kunye nokukhetha ukutya ukuze ufumane izondlo ozifunayo.
• Lawula uxinzelelo : Uxinzelelo olongezelelekileyo lunokunyusa iimpawu ze-TMAU. Ngoko ke, buza ugqirha wakho ngeendlela zokunceda ukunciphisa amanqanaba akho oxinzelelo. (umz., ukucamngca, i-yoga, umthambo wokuphefumla)
• Fumana inkxaso : I-Trimethylaminuria yimeko engaqhelekanga, ngoko ke ungaziva unesizungu kwaye ulahliwe. Ke ngoko, kunokuba luncedo kakhulu ukunxibelelana namaqela enkxaso apho abanye abanemeko efanayo banokufumaneka khona .

Ndifanele ndimbone nini ugqirha wam?

Ukuba iimpawu zakho aziphucuki nasemva kokwenza utshintsho kwindlela otya ngayo kunye nokulawula uxinzelelo, qiniseka ukuba ubona ugqirha wakho. Angathetha ngezinye iindlela zonyango onokuziqwalasela.

Ndingayibuza yiphi imibuzo ugqirha wam?

Ngenxa yokuba i-trimethylaminuria yimeko engaqhelekanga, usenokungazi nto ingako ngayo. Nazi ezinye zemibuzo onokuzibuza ugqirha wakho:

• Kutheni ndingene kule meko?
• Zeziphi iindlela zonyango ezilungileyo ondicebisa zona?
• Ungacebisa iqela lenkxaso okanye inkqubo apho ndinokufumana khona uncedo?

Ngaba abantu abane-trimethylaminuria bangazivumba bona ngokwabo?

Oku kukwayingxaki kubantu abaninzi. Ewe, sidla ngokuva ivumba lokubila kwethu kunye nevumba lomzimba, kwaye abantu abane-`(TMAU)` banokuliva ivumba labo. Nangona kunjalo, ngamanye amaxesha, xa sele beqhelile ivumba labo, basenokungaliboni ngendlela enamandla njengabanye. Kwakhona, ayingabo bonke abantu abanokuthi abaliva; abanye abantu basenokungaqapheli nokuba imizimba yabo inevumba elingaqhelekanga.

Okokugqibela, umyalezo obaluleke kakhulu

I-Trimethylaminuria yimeko enokwenza umntu angakwazi ukuzinceda, kungekuphela nje ngokwasemzimbeni, kodwa nangokwengqondo . Nokuba ayibangeli ntlungu emzimbeni, inokubangela intlungu enkulu kunye namanxeba engqondweni. Abanye abantu abanale meko bayazahlula kuluntu baze bazame ukuhlala bodwa, besoyika ukuba baya kuba yingxaki kwabanye. Nokuba emva kokutshintsha indlela abatya ngayo baze balandele ezinye iingcebiso, abanye abantu abane-`(TMAU)` baziva ngathi kusafuneka bagcine ubomi babo kude nabanye. Olu hlobo lokuzahlula kuluntu lunokubangela ukuba uphuhlise izinto ezifana nokudakumba kunye noxinzelelo.

Khumbula, awuwedwa . Ukuba unengxaki yesi sifo, nceda ungabi neentloni okanye ungoyiki ukucela uncedo kugqirha wakho. Banokuqonda oko ukutyhubelayo kwaye banokukuxelela ngeenkqubo kunye neenkonzo ezinokukunceda. Impilo yakho yengqondo ibaluleke njengempilo yakho yomzimba. Ngoko ke qiniseka ukuba ucingisisa ngayo.

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