Ingxaki yempilo eqhelekileyo uninzi lwethu olunayo luxinzelelo lwegazi oluphezulu , okanye " uxinzelelo " njengoko sonke sisazi. Ngamanye amaxesha, oku kunokulawulwa ngokuthatha amayeza achazwe ngugqirha. Kodwa kwabanye abantu, nokuba basebenzise hayi olunye, hayi ezimbini, kodwa iintlobo ezintathu okanye ezine zamayeza, olu xinzelelo alunakulawulwa kwaye baphantsi koxinzelelo olukhulu. Ngoko ke ukuba nawe unoxinzelelo lwegazi oluphezulu olunzima ukululawula, unobangela usenokuba yimeko ebizwa ngokuba yiHyperaldosteronism , esingakayiva kangako. Makhe sithethe ngale nto namhlanje.
Kulungile, ngoko ke yintoni iHyperaldosteronism?
Ngamafutshane, i-Hyperaldosteronism kukuveliswa ngokugqithisileyo kwehomoni ebizwa ngokuba yi-aldosterone yi -adrenal glands emzimbeni wethu.
Cinga nje, ii-adrenal glands zii-glands ezimbini ezincinci ezihlala njengesiciko phezu kwezintso zethu. I-hormone i-aldosterone eveliswa zezi glands ibaluleke kakhulu. Inceda ukugcina ulwelo olufanelekileyo, i-sodium ( ityuwa ) kunye ne-potassium emizimbeni yethu. Oko kukuthi, le hormone inceda umzimba ukuba ugcine i-sodium kunye namanzi owadingayo kwaye ikhuphe i-potassium engaphezulu kumchamo .
Ngoko ke, ukuba ngesizathu esithile le hormone ye-aldosterone ikhutshwa ngokugqithisileyo, siyibiza ngokuba yi-Hyperaldosteronism. Okwenzekayo ke kukuba umzimba ugcina i-sodium namanzi amaninzi, kwaye amanqanaba e-potassium ehla ngokuyingozi. Isiphumo esiphambili soku kukunyuka koxinzelelo lwegazi, okunzima kakhulu ukulilawula .
Kutheni le meko isenzeka?
I-Hyperaldosteronism inokwahlulwa ibe ziintlobo ezimbini eziphambili kuxhomekeke kwizizathu.
1. I-Hyperaldosteronism ePhambili
Ingxaki ikuyo i-adrenal gland ngokwayo. Oko kukuthi, i-adrenal gland ngokwayo ivelisa i-aldosterone hormone eninzi kakhulu ngaphandle kolawulo. Kukho izizathu ezahlukeneyo zoku.
| Isizathu | Inkcazo |
|---|---|
| I-Adenoma | Le yeyona nto ixhaphakileyo. Ithumba elingelomhlaza elikhula kwenye yeendlala ze-adrenal. Le meko ikwabizwa ngokuba yi-Conn's syndrome. |
| I-Bilateral Adrenal Hyperplasia | Ukwanda kwamadlala e-adrenal okanye ukukhula kakhulu kweeseli zawo. |
| Izimila ezinomhlaza | Kunqabile kakhulu, le meko inokubangelwa sisimila esinomhlaza kwi-adrenal gland. |
| Izizathu ezibangelwa lilifa | Ingabangelwa nasisifo semfuza esibizwa ngokuba yi-familial hyperaldosteronism. |
2. I-Secondary Hyperaldosteronism (I-Secondary Hyperaldosteronism)
Akukho nto imbi nge-adrenal gland koku. Nangona kunjalo, ngenxa yesinye isifo emzimbeni, i-adrenal gland iyakhuthazwa kwaye ivelisa i-aldosterone engakumbi. Oku kwenzeka ngokusebenzisa inkqubo ye-renin-angiotensin-aldosterone emzimbeni wethu.
| Iimeko zempilo ezinokwenzeka |
|---|
| I-stenosis yemithambo yezintso (ukuncitshiswa kwemithambo ehambisa igazi kwizintso) |
| Ukumelwa yintliziyo |
| Isifo sesibindi esingapheliyo |
| Ukukhulelwa |
| Ithumba elivelisa i-renin |
Zithini iimpawu zoku?
Khumbula, uphawu oluphambili noluqhelekileyo lwesi sifo luxinzelelo lwegazi oluphezulu, olunzima kakhulu ukululawula nokuba usebenzisa amayeza ambalwa aqhelekileyo.
Ukongeza kwiimpawu zoxinzelelo lwegazi oluphezulu, iimpawu zamanqanaba aphantsi e-potassium emzimbeni nazo zinokubonakala. Ngamanye amaxesha le meko inokubakho ngaphandle kweempawu.
| Udidi lweempawu | Iimpawu ezibonakalayo |
|---|---|
| Ngenxa yoxinzelelo lwegazi oluphezulu | Intloko ebuhlungu, isiyezi, ukubona izinto ezingaqondakaliyo, isifo sentliziyo. |
| Ngenxa yamanqanaba aphantsi e-potassium (i-Hypokalemia) | Iimeko ezinje ngokuba ndindisholo kwamalungu omzimba, ubuthathaka bemisipha, ukuqaqamba kwamalungu omzimba, kunye nokukhubazeka okwethutyana. |
| Ngenxa yokungalingani kolwelo kunye netyuwa | Ukusoloko ufuna ukuchama, ukuvuka ebusuku ukuze uchame, ukoma kakhulu, ukudinwa kakhulu. |
Ndingafumanisa njani ukuba oku kuyafumaneka?
Ukuba unoxinzelelo lwegazi oluphezulu olunzima ukululawula, ugqirha wakho unokurhanela le meko aze enze uvavanyo oluninzi.
- Uvavanyo lwegazi: Amanqanaba e-potassium, i-aldosterone, kunye ne-renin egazini lakho ayahlolwa. Kwi-primary hyperaldosteronism, i-potassium iphantsi kwaye i-aldosterone iphezulu. Kwi-secondary hyperaldosteronism, amanqanaba e-renin nawo aphezulu.
- Uvavanyo lomchamo: Umchamo oqokelelwe kwiiyure ezingama-24 uvavanywa ukuba unamanqanaba e-potassium.
- Uvavanyo lokufakwa kwetyuwa: Iipilisi zesodiyam zinikwa iintsuku ezi-3 okanye ityuwa inikwe emthanjeni iiyure ezi-4, emva koko amanqanaba e-aldosterone ajongwa egazini okanye emchameni.
- Uvavanyo lwemifanekiso: Uvavanyo olufana ne-CT scan lungasetyenziselwa ukujonga iithumba okanye ukwanda kwamadlala e-adrenal.
- Isampuli yemithambo ye-adrenal:Olu vavanyo lwenziwa ukuba iiskeni azinazo iziphumo ezipheleleyo. Oku kuquka ukuthatha iisampulu zegazi kwimithambo ye-adrenal glands zombini ukuze kuchongwe ukuba ingxaki ikwi-gland enye okanye zombini. Oku kudla ngokwenziwa ngaphambi kotyando.
- Uvavanyo lwemfuza: Ukuba umntu ongaphantsi kweminyaka engama-20 ubudala uba nale meko okanye ukuba kukho umntu kusapho lwakhe okhe waba nesi sifo, unokuthunyelwa kuvavanyo lwemfuza.
Iphathwa njani?
Iindlela zonyango zixhomekeke kwisizathu kunye nohlobo lwale meko.
- Utyando: Ukuba ingxaki yithumba kwi-adrenal gland enye, ugqirha wakho uya kucebisa utyando lwe-laparoscopic ukususa i-gland. Oku kubandakanya ukusikwa okuncinci okumbalwa, okunokukunceda uphile ngokukhawuleza kwaye kunciphise ukuhlala kwakho esibhedlele.
- Amayeza: Ukuba kukho ingxaki kuzo zombini ii-adrenal glands (bilateral hyperplasia), utyando alunakwenzeka. Endaweni yoko, kunikwa amayeza athintela ukusebenza kwehomoni i-aldosterone (umz., i-spironolactone, i-eplerenone). Nangona la mayeza engasinyangi isifo, anokuyilawula imiphumo yaso.
- Ezinye iindlela zonyango: Kwi-hyperaldosteronism yesibini, imeko engaphantsi (umz., isifo sentliziyo, i-renal artery stenosis) iyanyangwa.
- Utshintsho kwindlela yokuphila: Nokuba unyango lunjani na, kubalulekile ukwenza utshintsho oluthile kwindlela yokuphila ukuze ulawule uxinzelelo lwegazi oluphezulu.
- Ukuphepha utywala
- Ukuyeka ukutshaya
- Ukuzilolonga rhoqo
- Ukulawula ubunzima bomzimba
- Ukunciphisa ukutya ityuwa (i-sodium) ekutyeni
Zithini iingozi ukuba azinyangwa?
Ukuba i-hyperaldosteronism ayinyangwa ngokufanelekileyo, uxinzelelo lwegazi oluphezulu oluhlala ixesha elide kunye namanqanaba aphantsi e-potassium kunokukhokelela kwiingxaki ezinkulu.
- Uxinzelelo lwegazi oluphezulu lunokubangela: Ukuhlaselwa yintliziyo, istroke, ukungasebenzi kakuhle kwentliziyo, isifo sezintso, kwanokufa ngaphambi kwexesha.
- Amanqanaba aphantsi e-potassium anokubangela iimeko ezifana nobuthathaka bemisipha, ukukhubazeka, ukuqhina, iingxaki zokusebenza kwe-insulin, kunye nesifo seswekile.
Ngoko ke, ukuba uneempawu ezifana noxinzelelo lwegazi oluphezulu okunzima ukuzilawula, ukoma kakhulu, ukuchama rhoqo, okanye ubuthathaka bemisipha, qiniseka ukuba ubona ugqirha wakho uze uthethe ngayo. Musa ukoyika, le yimeko enokuxilongwa kwaye inyangwe.
Umyalezo Wokuya Ekhaya
- I-Hyperaldosteronism ibangelwa kukuba amadlala akho e-adrenal avelisa i-hormone eninzi kakhulu i-aldosterone.
- Uphawu oluphambili lwale nto luxinzelelo lwegazi oluphezulu olunzima ukululawula nokuba kusetyenziswe amayeza aliqela.
- Kwakhona, iimpawu ezinje ngamanqanaba aphantsi e-potassium emzimbeni, ubuthathaka bemisipha, kunye nokuqaqamba kwemisipha zinokubakho.
- Ukuba unale mpawu, thetha nogqirha wakho ngazo. Kubalulekile ukuba ungoyiki.
- Ngokuxhomekeke kwisizathu, le meko inokunyangeka ngempumelelo ngotyando, amayeza, kunye notshintsho kwindlela yokuphila.
I-Hyperaldosteronism, uxinzelelo lwegazi oluphezulu, ii-adrenal glands, i-aldosterone, i-potassium ephantsi, uxinzelelo, i-Conn's syndrome
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