Ngaba ngamanye amaxesha ukhe uzive ngathi imilenze yakho idumbile, ibuhlungu, okanye isifuba sakho siqinile? Ezi ayizozinto nje ezingaqhelekanga. Mhlawumbi isizathu soku kukungalingani okuncinci kwinkqubo yokuqina kwegazi emzimbeni wakho. Enyanisweni, ukuqina kwegazi emzimbeni wethu kubalulekile ukuze kusindiswe ubomi. Kodwa ukuba kwenzeka kakhulu, ngokungeyomfuneko, kukwayingozi kakhulu. Namhlanje sithetha ngovavanyo lwegazi olubalulekileyo olukhangela olo lungelelwaniso.
Yintoni iProtheyini S?
Ngamafutshane, iProtein S luhlobo olukhethekileyo lweproteyini eyenziwa sisibindi sethu. Umsebenzi wayo ophambili kukulawula inkqubo yokujiya kwegazi emizimbeni yethu.
Cinga ngenkqubo yakho yokuqina kwegazi njengenkqubo yokuqina kweebhuleki zemoto. Xa senzakele, ukuqina kwegazi kubalulekile ukuze kumiswe ukopha. Kufana nokuqina iibhuleki ukuze kumiswe imoto ngaphambi kokuba itshayise. Kodwa kwenzeka ntoni ukuba amahlwili egazi aqala emithanjeni yakho ngaphandle kwesizathu? Kufana nemoto eqhuba ngendlela eqhelekileyo endleleni kwaye ngequbuliso iibhuleki ziyavaleka kwaye onke amavili amane ayama.
Ngokufanayo, ukuba amahlwili egazi ayenzeka emithanjeni, anokuthintela ukuhamba kwegazi aze abangele iimeko eziyingozi. Iproteni S yinto elawula ukujiya kwegazi okungeyomfuneko, njengenxalenye ebalulekileyo yenkqubo yeebhuleki zomzimba wethu. Iproteni S yenza lo msebenzi ubalulekileyo kunye nezinye iiproteni ezifana neProteni C kunye ne-anti-thrombin.
Yintoni ukunqongophala kweProteni S?
Ukunqongophala kweProteni S kuthetha ukuba umzimba wakho awunayo eyaneleyo le protein ibalulekileyo. Xa oko kusenzeka, kuba ngathi inkqubo yeebhuleki endikhankanyileyo ngaphambili ibuthathaka. Oko kuthetha ukuba umngcipheko wokuqhekeka kwegazi kwimithambo yegazi uyanda ngokungeyomfuneko. Kwezonyango, le meko siyibiza ngokuba ngumngcipheko weVenous Thromboembolism (VTE).
Esi sisifo semfuza esidluliselwa kwizizukulwana ngezizukulwana. Kodwa asiqhelekanga kakhulu. Nangona kunjalo, kwezinye iimeko, umngcipheko wokuqhekeka kwegazi unokuba phezulu nangakumbi. Umzekelo:
- Ngexesha lokukhulelwa
- Xa usenza utyando
- Ukuba uthatha iipilisi zokulawula ukukhulelwa eziqulethe iihomoni
- Ukuba usebenzisa unyango lokutshintshwa kweehomoni (HRT)
- Xa uhlala kwindawo efanayo ixesha elide, njengakwiinqwelo moya.
Kodwa khumbula, ngamanye amaxesha amahlwili egazi anokwenzeka ngaphandle kwesizathu esithile. Le ngozi iyanda kancinci emva kweminyaka engama-55 ubudala.
Ziziphi iimeko eziyingozi ezenzekayo xa kungekho Protein S eyaneleyo?
Ukunqongophala kweProteni S kunokukhokelela kwiimeko ezimbini eziphambili eziyingozi. Masiziqonde ezi zinto ngetafile.
| Imeko | Ichazwe ngokulula kunye neempawu |
|---|---|
| I-Deep Vein Thrombosis (DVT) | Oku kwenzeka xa igazi liqhekeka (i-thrombus) livela kumthambo onzulu emzimbeni. Lidla ngokuvela emilenzeni. Iimpawu zingabandakanya ukudumba, iintlungu, imvakalelo efana ne-cramp emlenzeni omnye okanye engalweni, ukufudumala xa uchukunyiswa, kunye nokudumba komthambo. |
| Ukuxhuzula kweMiphunga (PE) | Oku kuyingozi nangakumbi. I-PE kuxa iqhekeza legazi elenziwe ngexesha le-DVT liqhekeka, lihamba ngegazi liye entliziyweni, lize libhajwe emthanjeni wegazi emiphungeni. Le yimeko engxamisekileyo, enokuba yingozi ebomini! Iimpawu ziquka ukuphefumla okukhawulezileyo, iintlungu ezibukhali zesifuba eziba mandundu xa uphefumla nzulu, ukubetha kwentliziyo ngokukhawuleza, kwaye ngamanye amaxesha ukhohlela igazi. Ukuba ufumana ezi mpawu, kufuneka uye kwicandelo likaxakeka lesibhedlele (ETU) ngoko nangoko. |
Yintoni uVavanyo lweProteni S?
Uvavanyo lwegazi olubaluleke kakhulu ukuze kuqinisekiswe ukuba usemngciphekweni na luvavanyo lweProtein S Activity. Olu vavanyo alulinganisi nje kuphela ubungakanani beProtein S egazini lakho, kodwa lukwalinganisa nokuba 'isebenza' kangakanani. Oko kukuthi, lulinganisa amandla ayo okuthintela ukujiya kwegazi. Lunokubona phantse zonke iintlobo zokungabikho kweProtein S.
Ukuba wenza olu vavanyo...
Ukuba ugqirha wakho ucela ukuba wenze olu vavanyo, ngokuqinisekileyo kufuneka uxelele ugqirha wakho malunga nawo onke amayeza owasebenzisayo (ingakumbi amayeza okunciphisa igazi kunye namahomoni). Kuba amanye amayeza anokutshintsha iziphumo zolu vavanyo. Kungoko ke, kubaluleke kakhulu ukuba uxele yonke into ngaphandle kokufihla nantoni na.
Ungaziqonda njani ixabiso kwingxelo yovavanyo?
Uluhlu oluqhelekileyo lomsebenzi weProtein S kwingxelo ludla ngokuba phakathi kwama -60% kunye nama-150% . Nangona kunjalo, oku kunokwahluka kancinci kwilabhoratri nganye. Ke ngoko, ugqirha wakho uza kuthelekisa iziphumo zakho noluhlu oluqhelekileyo kwingxelo yakho aze achaze kanye ukuba kuthetha ukuthini.
- Umsebenzi weProteni esezantsi: Oku kuthetha ukuba amandla omzimba wakho okulawula ukujiya kwegazi aphantsi. Oku kuthetha ukuba usemngciphekweni omkhulu wokufumana iimeko ezifana ne-DVT okanye i-PE.
- Ukuba ixabiso lomsebenzi weProtein S liphezulu (Phezulu): Eli xabiso liyanda kwabanye abantu, ingakumbi njengoko bekhula. Nangona kunjalo, akukafunyaniswa ukuba libangela naziphi na iingxaki ezinkulu zempilo. Oko kukuthi, ukunyuka kweli xabiso akonyusi umngcipheko wokopha.
Ngubani ofuna ukwenza olu vavanyo?
Ugqirha wakho angacebisa olu vavanyo ukuba ucinga ukuba usemngciphekweni wokuba nesifo sokujiya kwegazi, ingakumbi ukuba:
- Ukuba unegazi elijiyileyo emzimbeni wakho ngaphandle kwesizathu esicacileyo (umzekelo, utyando, uhambo olude, njl.njl.).
- Ukuba kukho umntu kusapho lwakho onembali yokuqhekeka kwegazi rhoqo (i-Venous Thromboembolism - VTE).
- Ukuba kukho umntu kusapho lwakho osele efunyenwe ukuba une-Protein S enqongopheleyo.
- Ukuba uphunyelwe sisisu izihlandlo ezingaphezu kwesinye.
Ngokusekelwe kwiziphumo zolu vavanyo, ugqirha wakho uya kukwazi ukukunika amayeza okukunceda uthintele ukuqhekeka kwegazi okungaqhelekanga.
Umyalezo Wokuya Ekhaya
- Iproteni S yiproteni ebalulekileyo elawula ukujiya kwegazi emzimbeni wethu, isebenza njenge "brake".
- Ukuba eli nqanaba leProtein S liyancipha, umngcipheko wokufumana iimeko eziyingozi ezifana ne-DVT (deep vein thrombosis) kunye ne-PE (pulmonary embolism) uyanda.
- Uvavanyo lweProtein S Activity luvavanyo olubalulekileyo lwegazi lokuvavanya lo mngcipheko.
- Ukuba uvavanywa olu vavanyo, kubalulekile ukwazisa ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
- Ukuba wena okanye usapho lwakho ninembali yokuqhekeka kwegazi okungachazwanga, thetha nogqirha wakho ngayo uze ufumane icebiso elifunekayo.
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