Iyini i-DHT? Iyithinta kanjani umzimba wakho? (i-Dihydrotestosterone)

Wake wezwa nge-DHT noma i-Dihydrotestosterone ? Mhlawumbe yebo, mhlawumbe cha. Kodwa lokhu kuyinto ebaluleke kakhulu emzimbeni wethu, ikakhulukazi empilweni yamadoda. Ngakho-ke, namuhla sizokhuluma ngale DHT ngendlela elula ongayiqonda.

Kuyini i-DHT (i-dihydrotestosterone)? Kalula nje...

Kalula nje, i-DHT iyi-hormone ekhethekile esiza ekuthuthukiseni izici zobulili zesilisa . Uyazi, ama-hormone afana nezithunywa ezincane ezilawula yonke imisebenzi emzimbeni wethu. I-DHT iphinde ibe seqenjini lama-hormone abizwa ngokuthi i-Androgen. I-Androgen igama elinikezwa ama-hormone abangela izici zesilisa.

Cabanga ngakho, i-DHT iqala ukusebenza emzimbeni wowesilisa kusukela ngesikhathi esesibelethweni. Ngemuva kwalokho, indima ye-DHT iyashintsha ngezikhathi ezahlukene empilweni yakhe. Nakuba ososayensi bengaqiniseki kahle ukuthi i-DHT ibathinta kanjani abesifazane, bacabanga ukuthi ingathinta ukukhula kwezinwele emzimbeni nasezindaweni zangasese.

I-androgen eyinhloko kumuntu wesilisa omdala yi -testosterone . Cishe u-10% walesi testosterone uguqulwa ube yi-DHT nsuku zonke . Le nqubo yenzeka esikhumbeni esizungeze izitho zangasese kanye nase-prostate gland kwabesilisa. Kwabesifazane, lokhu kwenzeka esikhumbeni. Kwenzeka nasezindaweni ezifana nesibindi sethu. Ngenxa yokuthi amadoda ngokwemvelo ane-testosterone eningi emizimbeni yawo, amazinga awo e-DHT nawo aphezulu kakhulu.

Yini ngempela eyenziwa yi-DHT emizimbeni yethu?

I-DHT yenza izinto ezahlukene ezigabeni ezahlukene zokuphila kwendoda. Ibaluleke kakhulu ngesikhathi sokukhula kwengane kanye nokuthomba .

Nokho, ngokungafani ne-testosterone, i-DHT ayidlali indima enkulu ekugcineni imisebenzi yomzimba kumuntu wesilisa omdala. Lapho umuntu esemdala, i-DHT ibonakala kakhulu ezimweni ezifana nokukhula kwe-prostate kanye nokulahlekelwa izinwele ngendlela yabesilisa.

Indima ye-DHT ngesikhathi sesigaba sombungu

Ngesikhathi esesibelethweni, izitho zobulili zomntwana zikhula njengowesilisa noma owesifazane kuye ngendawo ethile yamahomoni. Endabeni yomfana, i-DHT isebenza namanye amahomoni (kufaka phakathi i-testosterone ) ukucindezela ukuthuthukiswa kwezici zobulili zowesifazane nokukhuthaza ukuthuthukiswa kwezici zobulili zowesilisa .

I-DHT ibalulekile ekukhuleni kwezitho zangasese zabesilisa, ipenisi namasende, embungwini. I-DHT iyasiza nasekukhuleni kwendlala ye-prostate.

I-DHT ngesikhathi sokuthomba

Njengoba umfana efika esikhathini sokuthomba, i-DHT isiza ipenisi namasende ukuthi akhule kakhulu. Akukhona lokho kuphela, kodwa i-DHT nayo inesibopho kakhulu salokhu:

• EbusweniUkukhulisa intshebe.
• Ukukhula kwezinwele emzimbeni.
• Ukukhula kwezinwele ezindaweni eziyimfihlo.
• Ukukhula kwe-prostate .

Kwenzekani uma amazinga e-DHT enyuka?

Ezinye izimo zempilo zihlotshaniswa namazinga aphezulu e-DHT. Ake sibheke ukuthi ziyini:

• I-Benign Prostatic Hyperplasia (BPH)
• Umdlavuza we-prostate
• I-Androgenetic alopecia (ukulahlekelwa izinwele kwabesilisa )
• I-Polycystic Ovarian Syndrome (PCOS) (kwabesifazane)

I-Benign Prostatic Hyperplasia (BPH) kanye ne-DHT

I-Benign Prostatic Hyperplasia (BPH) iwukukhula kwendlala yakho ye-prostate. Kuyisifo esivame kakhulu kwabesilisa abangaphezu kweminyaka engu-50 .

Indlala yakho ye-prostate ingakhiqiza inani elikhulu le-DHT. Le DHT ivuselela ukusebenza okuvamile kwendlala ye-prostate, futhi ivame ukubangela ukuthi indlala ye-prostate ikhule. Le BPH ingabangela izinkinga ezifana nobunzima bokuchama kanye nokungasebenzi kahle kocansi .

Umdlavuza we-prostate kanye ne-DHT

Abantu abanomdlavuza we-prostate bavame ukuba namazinga aphezulu e-DHT. Umdlavuza we-prostate ungabangelwa ukwanda komsebenzi we-DHT ku-prostate yakho, kuhlanganiswe nokuguqulwa kwezakhi zofuzo ezithile okubangela ukuba amangqamuzana e-prostate akhule ngokungalawuleki.

I-Androgenetic alopecia (ukulahlekelwa izinwele) kanye ne-DHT

I-Androgenic alopecia yilokho esivame ukukubiza ngokuthi i-pattern baldness yabesilisa . Kulesi simo, izinwele ziyawa kusukela phezulu nangaphambili kwekhanda. Ngokuhamba kwesikhathi, izinwele ziyaphela.

Esinye sezimbangela zalokhu kulahlekelwa izinwele ukwanda komsebenzi we-DHT kuma-follicle ezinwele zakho. Kunezinye izimbangela, njengethonya lezakhi zofuzo. Lapho amazinga e-DHT enyuka, ama-follicle ezinwele ayancipha, umjikelezo wokukhula kwezinwele uyafinyela, futhi ekugcineni izinwele ziyawa.

I-PCOS kanye ne-DHT

I-Polycystic Ovarian Syndrome (PCOS) ukungalingani kwama-hormone okuthinta abesifazane. Kwenzeka lapho ama-ovari abo ekhiqiza ama-hormone amaningi kakhulu e-androgen, kufaka phakathi i-testosterone. Lokhu kuholela emazingeni aphezulu e-DHT. Lokhu kungabangela izimpawu ezahlukahlukene, kufaka phakathi ukuya esikhathini okungajwayelekile, ukukhula ngokweqile kwezinwele zomzimba (i-hirsutism), kanye ne-acne .

Kwenzekani uma amazinga e-DHT ehla?

Ezinye izimo zihlotshaniswa namazinga aphansi e-DHT. Ake sibheke ukuthi ziyini:

• Ukuntuleka kwe-5-alpha reductase `(ukuntuleka kwe-5-alpha reductase)`
• I-testosterone ephansi / i-hypogonadism yabesilisa

Amazinga aphansi kunejwayelekile e-DHT athinta kakhulu amadoda. Abanye ososayensi bakholelwa ukuthi amazinga aphansi e-DHT emantombazaneni angase abambezele ukuthomba.

Ukuntuleka kwe-5-alpha reductase kanye ne-DHT

I-5-alpha reductase iyi-enzyme esiza ukuguqula i-testosterone ibe yi-DHT. Ukuguqulwa kwezakhi zofuzo okuthinta ukukhiqizwa kwale enzyme kungabangela amazinga e-DHT ukuba aphansi noma angabi khona. Lokhu kubizwa ngokuthi ukuntuleka kwe-5-alpha reductase. Lesi yisimo esizuzwa kubazali kubantwana (iphethini yokubuyisa i-autosomal) .

Ukuntuleka kwe-5-alpha reductase kuthinta ukukhula ngokocansi kwezingane zesilisa ezizalwa ngofuzo (lezo ezine-chromosomes ye-XY). Izingane zesilisa ezizalwa nalokhu kuntuleka zivame ukukhombisa izici ezilandelayo:

• Izitho zangasese zangaphandle azikakhuli ngokugcwele.
• Ukuba khona kwamasende asebenzayo emzimbeni (angaphumi).
• Indlala ye-prostate encane noma engekho.

Okubalulekile: Ezimweni ezimbi kakhulu zokuntuleka kwe-5-alpha reductase, izingane zesilisa ezizalwa ngofuzo ezinama-chromosome e-XY zingase zibe nezitho zangasese zabesifazane zangaphandle. Kodwa-ke, i-DHT encishisiwe ayithinti ukukhula kwama-testicles (asengakhiqiza isidoda) kanye nezitho zangasese zangaphakathi. Lokhu kuhlukile esimweni esibizwa ngokuthi i-Androgen Insensitivity Syndrome. Abantu abanalesi simo banama-testicles ajwayelekile kanye namazinga e-testosterone ajwayelekile noma aphezulu, kodwa abanawo ama-receptor e-androgen, ngakho-ke abathuthukisi izici zocansi zesibili, futhi futhi abavundi kakhulu.

Abafana abanesifo sofuzo sokuntuleka kwe-5-alpha reductase abakhi izinwele ebusweni lapho befika esikhathini sokuthomba. Kodwa-ke, imizimba yabo isakhiqiza i-testosterone, okuholela ezintweni ezifana nezwi elijulile, ukukhula kwemisipha, kanye nokukhula kwepenisi.

Amazinga aphansi e-testosterone kanye ne-DHT

I-Testosterone emzimbeni wakho yiyo eguqula ibe yi-DHT. Ngakho-ke, uma amazinga akho e-testosterone ephansi, amazinga akho e-DHT nawo azoba ngaphansi kunokuvamile. Elinye igama lamazinga aphansi e-testosterone yi-hypogonadism yabesilisa.

Kunezinhlobo ezimbili eziyinhloko ze-hypogonadism yabesilisa: eyakudala (ekhona lapho uzalwa noma kamuva ekuphileni) kanye neyokuqala sekwephuzile. Kuye ngeminyaka yakho, i-hypogonadism yabesilisa ingabangela izinkinga ezahlukahlukene.

Ingabe kufanele ngibone udokotela mayelana namazinga ami e-DHT?

Uma ucabanga ukuthi wena noma ingane yakho ningaba nesifo esibangelwa yi-DHT ephansi noma ephezulu, qiniseka ukuthi ukhuluma nodokotela.Ngemuva kwalokho angenza izivivinyo ezidingekayo noma akuthumele kumuntu ochwepheshe ohlelweni lwe-endocrine, njengodokotela we-endocrinologist.

I-Dihydrotestosterone, noma i-DHT, ibalulekile ekukhuleni kobulili kwabesilisa. Kodwa uma amazinga ayo ephezulu kakhulu noma ephansi kakhulu, ingabangela izinkinga ezifana nokungakhuli kahle kwezitho zangasese zangaphandle, ukwanda kwe-prostate, kanye nokulahlekelwa izinwele. Uma unenkinga ngamazinga akho e-DHT, ungangabazi ukukhuluma nodokotela wakho. Bangenza izivivinyo futhi batuse ukwelashwa okungakusiza.

Izinto ezibaluleke kakhulu okufanele uzikhumbule kulesi sihloko (Umyalezo Wokuya Ekhaya)

• I-DHT iyi-hormone ye-androgen esiza kakhulu ekuthuthukiseni izici zobulili zabesilisa .
• I-DHT ibalulekile ekuthuthukisweni kwezitho zangasese zabesilisa ngesikhathi sesigaba sokukhulelwa kanye nasekukhuleni kwezinwele zobuso nezinwele zomzimba ngesikhathi sokuthomba.
• Amazinga aphezulu e-DHT angaholela ezimweni ezifana ne-benign prostatic hyperplasia (BPH), umdlavuza we-prostate, ukulahlekelwa izinwele kwabesilisa, kanye ne-PCOS kwabesifazane.
• Uma amazinga e-DHT ephansi, izimo ezifana nokuntuleka kwe-5-alpha reductase zingathinta ukukhula kobulili kwabesilisa.
• Uma unemibuzo noma ukukhathazeka ngamazinga akho e-DHT, kungcono ukufuna iseluleko sezokwelapha .

Ngithemba ukuthi usuyaqonda kangcono i-DHT. Ukuqaphela izinto ezinjengalezi kubaluleke kakhulu empilweni yakho!

I- DHT, i-dihydrotestosterone, ama-hormone, impilo yamadoda, i-testosterone, i-prostate, ukulahleka kwezinwele, i-PCOS