Ngezinye izikhathi lapho udokotela ekutshela ukuthi wenze ukuhlolwa kwegazi, awukwazi ukuthola ukuthi kusho ukuthini noma ukuthi ufunani, akunjalo? Ukuhlolwa kwe-ANCA kungenye yamagama angajwayelekile. Kodwa asikho isizathu sokwesaba noma sokukhathazeka ngoba nje uzwa leli gama. Namuhla, sizoxoxa ngalokho elikufunayo, ukuthi kungani lenziwa, nokuthi imiphumela isho ukuthini ngendlela elula kakhulu ongayiqonda.
Kalula nje, luyini lolu vivinyo lwe-ANCA?
Ukuhlolwa kwe-ANCA kuwukuhlolwa okuthatha isampula yegazi lakho. Kuhlola kakhulu ukuthi kukhona yini into ebizwa ngokuthi ama-antineutrophil cytoplasmic antibodies ( i-ANCA ngamafuphi) egazini lakho.
Manje ungase uzibuze ukuthi liyini lelo gama. Ake silichaze kalula futhi siqonde.
Cabanga nje ukuthi imizimba yethu ifana nezwe. Kukhona ibutho lokuvikela leli lizwe. Lelo butho liyisimiso sethu somzimba sokuzivikela . Uhlobo olukhethekile lwesosha kuleli butho lubizwa ngokuthi ama-neutrophils . Umsebenzi wabo ukulwa nezitha ezifana namagciwane namagciwane angena emizimbeni yethu futhi asivikele ezifweni.
Kodwa ngezinye izikhathi amasosha ethu omzimba ayaphazamiseka. Amasosha ethu omzimba aqala ukuhlasela amangqamuzana ethu amahle. Yile ndlela esibiza ngayo ama-autoantibodies , amaprotheni akhiqizwa ngokumelene nemizimba yethu.
I-ANCA ingenye yama-autoantibody anjalo. Lokho okwenziwa yi-ANCA ukuhlasela amangqamuzana amhlophe egazi abizwa ngokuthi ama-neutrophils asivikelayo. Ngakho-ke ukuhlolwa kwe-ANCA kulinganisa ukuthi kukhona yini ama-autoantibodies egazini lakho asebenza ngokumelene nemizimba yethu, futhi uma kunjalo, mangaki awo akhona.
Kungani udokotela angakutshela ukuthi wenze lokhu kuhlolwa kwe-ANCA?
Udokotela uvame uku-oda lokhu kuhlolwa uma esola isimo esibizwa ngokuthi i-vasculitis .
Kalula nje, i-vasculitis ukuvuvukala kwemithambo yegazi (imithambo yegazi) emzimbeni wethu. Njengoba nje ipayipi lamanzi livuvukala, kuba nzima ngamanzi ukugeleza kulo. Lapho imithambo yegazi ivuvukala, ukugeleza kwegazi kuyavaleka futhi izitho ezahlukahlukene emzimbeni wethu zingalimala. Lesi yisifo esibangelwa ukuzivikela komzimba, okusho ukuthi sibangelwa ukusebenza kwesimiso sethu somzimba sokuzivikela.
Kunezinhlobo eziningana eziyinhloko ze-vasculitis ezihlotshaniswa nama-autoantibodies abizwa ngokuthi i-ANCA. Uma unezinye zalezi zimpawu, lokhu kuhlolwa kungasiza ekuqinisekiseni lokho.
| Izinhlobo ze-Vasculitis ehlobene ne-ANCA | Igama langaphambilini |
|---|---|
| I-granulomatosis ene-polyangiitis | I-granulomatosis kaWegener |
| I-Microscopic polyangiitis | - |
| I-granulomatosis ye-eosinophilic ene-polyangiitis | I-Churg-Strauss syndrome |
Ukuvuvukala kwemithambo yegazi kungaphazamisa ukuhlinzekwa kwegazi ezithweni ezibalulekile njengenhliziyo, amaphaphu nezinso. Ngakho-ke, kubaluleke kakhulu ukuxilonga nokwelapha lezi zimo kusenesikhathi.
Ingabe zikhona izinhlobo ze-ANCA?
Yebo, kunezinhlobo ezimbili eziyinhloko ze-ANCA. Lezi zingashiwo embikweni wakho wokuhlolwa.
1. i-cANCA: Lokhu kuhlasela iphrotheni ebizwa ngokuthi i-proteinase 3 (PR3) .
2. i-pANCA: Lokhu kuhlasela iphrotheni ebizwa ngokuthi i-myeloperoxidase (MPO) .
Ukwazi ukuthi yiluphi kulezi zinhlobo ezimbili onalo emzimbeni wakho kuzosiza udokotela wakho ukuthi athole ukuthi hlobo luni lwe-vasculitis onalo.
Indlela yokwenza isivivinyo nokulungiselela
Lena inqubo elula kakhulu. Awudingi ukwenza lutho olukhethekile ukuze ulungiselele lokhu. Kodwa-ke, ngezinye izikhathi udokotela wakho uzoyala ezinye izivivinyo eziningana zegazi kanye nalokhu kuhlolwa. Ezimweni ezinjalo, ungase ucelwe ukuba uzile ukudla amahora angu-8 kuya kwangu-12, ngaphandle kokudla namanzi kuphela. Udokotela wakho uzokunikeza imiyalelo eqondile ngalokhu.
Kwenzekani ngesikhathi sokuhlolwa?
Lokhu kufana nje nokuhlolwa kwegazi. Kuqedwa ngemizuzu embalwa.
- Umhlengikazi noma udokotela uzokhetha umthambo ofanele engalweni yakho eduze kwendololwane yakho ukuze akhiphe igazi.
- Leyo ndawo ihlanzwa ngesibulali-magciwane.
- Inaliti encane ibe isifakwa emthanjeni bese inani legazi elidingekayo liqoqwa lifakwe epayipini. Ungase uzizwe umuzwa omncane wokuhlaba lapho inaliti ifakwa, kodwa kungokwesikhashana.
- Uma igazi selikhishiwe, inaliti iyasuswa, ucezu lwekotini lubekwa phezu kwendawo bese kufakwa ingcindezi. Bese kufakwa iplasta encane endaweni.
Kwenzekani ngemva kokuhlolwa?
Ngemva kokukhipha igazi, ungenza imisebenzi yakho evamile. Kodwa udokotela uzokutshela ukuthi ugcine iplasta amahora ambalwa. Angase futhi akutshele ukuthi ugweme ukuzivocavoca okunzima ngalolo suku.
Ukukhishwa kwegazi lakho kuphephile kakhulu. Esikhathini esiningi, indawo lapho inaliti ifakwe khona ingase ibe luhlaza okwesibhakabhaka kancane, okuvame ukunyamalala ngokwayo ngosuku olulodwa noma ezimbili. Akuvamile kakhulu, umthambo ungavuvukala kancane. Uma lokhu kwenzeka, ungathola impumuzo ngokuwufaka emanzini afudumele.
Kuthatha isikhathi esingakanani ukuthi umbiko ufike? Ithini imiphumela?
Ngenxa yokuthi ukuhlolwa kwe-ANCA kuwukuhlolwa okukhethekile, kungathatha izinsuku ezimbalwa noma isonto ukuthola imiphumela. Uma umbiko usufikile, udokotela wakho uzochaza ukuthi kusho ukuthini kuwe.
- Uma umphumela ungemuhle:
Lokhu kusho ukuthi awunawo ama-autoantibodies e-ANCA egazini lakho. Lokho kusho ukuthi cishe akunakwenzeka ukuthi ube ne-ANCA-associated autoimmune vasculitis. Lezi yizindaba ezinhle.
- Uma umphumela uwukuthi Ulungile:
Lokhu kusho ukuthi unama-autoantibodies abizwa ngokuthi i-ANCA egazini lakho. Lokhu kusho ukuthi ungase ube nesifo se-autoimmune vasculitis.
Kodwa into ebaluleke kakhulu okumele uyikhumbule lapha ukuthi ukuthi ukuhlolwa kwe-ANCA kuveze ukuthi kune-positive akuqinisekisi ngokuphelele ukuthi une-vasculitis.
Ukuze athole ukuxilongwa okunembile, udokotela uzocabangela ezinye izici eziningana:
- Ziyini izimpawu zakho?
- Yini etholakale ngesikhathi sokuhlolwa ngokomzimba?
- Iyini imiphumela yokuhlolwa kwegazi nomchamo okunye?
- Ngezinye izikhathi, ungase ucelwe ukuba wenze i-biopsy, ehilela ukuthatha ingxenye encane yezicubu esithweni esithintekile bese uyihlola.
Ngakho-ke, ungesabi ukucabanga ngombiko wedwa. Umuntu ongcono kakhulu ongawuqonda lo mbiko udokotela wakho. Uzohlanganisa konke futhi afinyelele esiphethweni esinembile kakhulu ngesimo sakho.
Umlayezo Wokuya Nawe Ekhaya
- Ukuhlolwa kwe-ANCA ukuhlolwa kwegazi okukhethekile okuthola izifo ezithile ezibangelwa amasosha omzimba ethu, njenge-vasculitis.
- Lokhu ukuhlolwa okulula nokuphephile, njengokuhlolwa kwegazi okuvamile. Akudingi ukulungiswa okukhethekile.
- Ungakhathazeki uma imiphumela yokuhlolwa 'ibonisa ukuthi unesifo'. Yona yodwa ayikwazi ukunquma ukuthi unesifo yini.
- Khuluma nodokotela wakho ngokukhululekile mayelana nombiko wakho, ukuthi usho ukuthini, nokuthi yini okufanele uyenze ngokulandelayo. Uzokuchazela konke.
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