Usho ukuthini umbiko wakho wegazi we-AST? (Ukuhlolwa kwe-Aspartate Aminotransferase) Ake sikuchaze kalula!

Uke wahlolwa igazi muva nje? Uke wazizwa wesaba noma ukhathazekile lapho ubona ukuthi inani le-AST liphakeme kancane kunezinga elijwayelekile embikweni? Noma ingabe udokotela ukubhalele ukuthi wenze ukuhlolwa kwe-AST? Abantu abaningi bayasaba lapho bezwa igama elithi AST. Kodwa ungesabi, kuyinto evamile. Namuhla, sizoxoxa ngakho konke ngokuningiliziwe, ngendlela ongayiqonda, nangendlela elula.

Kalula nje, iyini le AST?

I-AST isifinyezo se- Aspartate Aminotransferase . Lena yi-enzyme emzimbeni wethu, okuwuhlobo lweprotheni. Le enzyme ikhiqizwa kakhulu yisibindi sakho. Kodwa-ke, ngaphezu kwesibindi, inhliziyo, izinso, ubuchopho, kanye nemisipha nakho kukhiqiza inani elincane lale enzyme ye-AST.

Cabanga nge-AST "njengesisebenzi" esihlala ngaphakathi kwamaseli esibindi. Ngokuvamile, lawa "basebenzi" angaphakathi kwesibindi. Kodwa kuvamile ukuthi inani elincane kakhulu lawo liqoqeke egazini. Kodwa-ke, uma isibindi sonakele ngesizathu esithile, njengalapho udonga endlini luphuka futhi okuqukethwe ngaphakathi kuphuma, lawa "basebenzi" be-AST ngaphakathi kwamaseli esibindi avuza egazini ngobuningi obukhulu. Yilapho ukuhlolwa kwegazi kukhombisa ukwanda kwamazinga e-AST.

Kodwa khumbula, izinga le-AST eliphakeme akusho njalo ukuthi kunenkinga yesibindi. Ngoba, njengoba sishilo ngaphambili, amazinga e-AST angakhuphuka uma ezinye izitho zomzimba, njengenhliziyo nezinso, zonakele. Yingakho odokotela bevame uku-oda ezinye izivivinyo eziningana kanye nokuhlolwa kwe-AST.

Umehluko phakathi kwe-AST ne-ALT

Uma udokotela enza ukuhlolwa kwe-AST, bavame ukwenza nokuhlolwa kwe -ALT (i-Alanine Transaminase) ngesikhathi esifanayo. I-ALT ingenye i-enzyme etholakala esibindini. Kodwa ngokungafani ne-AST, i-ALT incike kakhulu esibindini . Lokhu kusho ukuthi uma izinga le-ALT liphakeme, kungenzeka kakhulu ukuthi kube nenkinga esibindini.

Odokotela bathi ukuqhathanisa amazinga e-AST kanye ne-ALT ndawonye kunganikeza umbono ocacile ngesimo kanye nobunzima besifo sesibindi, kunokubheka izinga le-AST lodwa.

Kungani udokotela angakutshela ukuthi wenze ukuhlolwa kwe-AST?

Ukuhlolwa kwe-AST kungaba yingxenye yephaneli ephelele ye-metabolic eyenziwa udokotela wakho ukuhlola impilo yakho iyonke. Ngaphezu kwalokho, udokotela wakho angayala lokhu kuhlolwa uma unezimpawu ezibonisa ukulimala kwesibindi.

Ezinye izimpawu ezibonisa ukulimala kwesibindi:

• Ukuphuzi kwamehlo noma isikhumba (i-jaundice)
• Ukukhathala ngokweqile kanye nobuthakathaka ngaphandle kwesizathu
• Ukuqunjelwa noma ukuvuvukala kwesisu
• Isicanucanu nokuhlanza
• Isisu esibuhlungu
• I-Anorexia
• Isikhumba esilumayo
• Umchamo omnyama (njengombala wetiye)
• Isihlalo esinombala okhanyayo (njengompunga)
• Ukuvuvukala kwemilenze namaqakala
• Isikhumba esiphuka kalula ngisho nangemva kokulimala okuncane

Ngisho noma ungenazo lezi zimpawu, udokotela wakho angancoma lokhu kuhlolwa uma usengozini enkulu yokuthola isifo sesibindi.

Uziqonda kanjani izindinganiso ezisembikweni we-AST?

Ngokuvamile uzothola umbiko zingakapheli usuku olulodwa noma ezimbili. Amanani aqoshwa ngamayunithi ngelitha (amayunithi/L).

Into ebalulekile ukuthi awukwazi ukwenza isinqumo esiphelele mayelana nempilo yesibindi sakho ngokusekelwe ezingeni lakho le-AST kuphela. Udokotela wakho uzocabangela leli nani kanye nakho konke okunye, njengezinga lakho le-ALT, izimpawu zakho, kanye nomlando wakho wezokwelapha.

Izinga le-AST elijwayelekile

Akukho "uhla olujwayelekile" olulodwa olusebenzela wonke umuntu. Leli nani lingahluka kuye ngelebhu ehlola igazi lakho, iminyaka yakho, isisindo sakho, kanye nobulili. Kodwa ngokuvamile, inani lamayunithi angu-8 kuya kwangu-33/L libhekwa njengelijwayelekile. Kodwa ububanzi obujwayelekile embikweni wakho yibo obubalulekile kuwe.

Izinga le-AST eliphakeme (i-AST ephezulu)

Kungaba nezizathu eziningana zokuthi kungani amazinga e-AST ephakeme kunokujwayelekile.

• Izimbangela ezihlobene nesibindi:
• Isifo sesibindi esihlobene notshwala
• Isifo sesibindi esinamafutha (MASLD)
• I-hepatitis engapheli
• Ukuqina kwesibindi noma izibazi (i-Cirrhosis)
• Ukuncipha kokunikezwa kwegazi esibindini (i-ischemia yesibindi)
• Umdlavuza wesibindi
• Ezinye izimbangela ezingahlobene nesibindi:
• Isifo senhliziyo
• Ukulimala kwemisipha (isb. ngemva kokuvivinya umzimba okunzima)
• Ukukhulelwa
• I-Pancreatitis
• Ezinye izifo ezibangelwa amagciwane, njenge-mononucleosis
• Eminye imithi

Amazinga aphezulu kakhulu e-AST (angaphezu kwamayunithi angu-500/L) angabonakala ezimweni ezifana ne-hepatitis ebangelwa yigciwane, umonakalo omkhulu wesibindi obangelwa izidakamizwa noma ubuthi.

Izinga le-AST eliphansi (i-AST ephansi)

Izinga eliphansi le-AST ngokuvamile liyinto enhle. Kodwa-ke, ezimweni ezingavamile, njengokuntuleka kwe-vitamin B6, amazinga e-AST nawo angaba phansi. Lokhu akusikho okufanele ukhathazeke ngakho, udokotela wakho uzokuchazela.

Ingabe amazinga e-AST angancishiswa?

Yebo, kungenzeka ngempela! Ungabuyisela izinga lakho le-AST esimweni esijwayelekile ngokukhuluma nodokotela wakho ukuze uqonde imbangela yezinga lakho eliphezulu le-AST futhi uthathe izinyathelo ezifanele.

• Uma ukhuluphele kakhulu, yehlisa isisindo.
• Yeka ukuphuza utshwala ngokuphelele noma unciphise kakhulu.
• Yamukela ukudla okunempilo. Nciphisa ukudla okunamafutha, okunoshukela, nokunofulawa bese udla imifino, izithelo, namakhambi amaningi.
• Vivinya umzimba njalo. Ngisho nokuhamba imizuzu engama-30 ngosuku kungasiza.

Isibindi sethu siyisitho esimangalisayo. Ngaphandle kokuthi sibe nesifo esibi njenge-cirrhosis, uma sisusa imbangela yokulimala kwesibindi, sinekhono elimangalisayo lokuzelapha . Ngakho-ke, kubaluleke kakhulu ukuhlonza lesi simo kusenesikhathi bese sithatha izinyathelo ezifanele.