Wake wezwa ngomdlavuza wobuchopho? Empeleni kuyisimo esiyingozi kakhulu futhi esinzima ukwelapha. Ngoba ubuchopho bethu buyindawo evikelekile kakhulu emzimbeni. Akuzona zonke izinto ezingangena kalula lapho. Ngenxa yalesi sivikelo, ngisho nemithi esetshenziselwa umdlavuza (i-chemotherapy) ayikwazi ukufinyelela amangqamuzana omdlavuza ebuchosheni. Kodwa manje ososayensi bathole ikhambi elimangalisayo kulokhu.
Iyini le Blood-Brain Barrier?
Kalula nje, lokhu kufana nodonga oluvikelekile oluzungeze ubuchopho bethu. Cabanga ukuthi ubuchopho bethu buyisakhiwo esibaluleke kakhulu nesiphephile ezweni. Umnyango waleyo sakhiwo udlula esangweni eliqinile kakhulu. Leli sango livimbela amagciwane namakhemikhali angafuneki egazini lethu ukuthi angangeni ebuchosheni. Lokhu yilokho esikubiza ngokuthi i-Blood-Brain Barrier kwezokwelapha.
Lokhu kuvikelwa kubalulekile kithi. Kodwa inkinga iwukuthi, lolu hlelo lokuzivikela luphatha ngisho nemithi yokwelapha ngamakhemikhali 'njengezivakashi ezingafuneki' futhi aluvumeli ukuba ingene. Ngakho-ke, ukwelapha umdlavuza wobuchopho sekuyinselele yangempela kodokotela.
Isixazululo sakamuva sososayensi: I-implant encane encibilikayo!
Ithimba lososayensi selithole ikhambi elisha lale nselele: i-implant encane encibilika emzimbeni bese ifakwa ngaphakathi kogebhezi, eduze nendawo lapho kukhona khona isimila sobuchopho.
Le gajethi encane, ibhokisi elincane elingaba yisentimitha ububanzi ukuze kube nembile, yenziwe nge-amino acid ekhethekile. Ibizwa ngokuthi i-glycine . Okukhethekile ngayo ukuthi uma kusetshenziswa ugesi omncane kuyo, iyavevezela futhi ikhiphe amaza omsindo avame kakhulu, noma amaza e-ultrasound , angezwakali endlebeni yomuntu. Le nqubo ibizwa ngokuthi umphumela we-piezoelectric .
Manje cabanga ukuthi udokotela ufaka umuthi wokulwa nomdlavuza, njenge-paclitaxel, emzimbeni. Ngesikhathi esifanayo, idivayisi elawulwa ngaphandle inikeza ugesi kulowo mthambo omncane ebuchosheni. Bese kuthi, amaza e-ultrasound akhishwa yiwo abangele ukuthi amangqamuzana e-Blood-Brain Barrier esikhulume ngawo anyakaze kancane, adale izikhala ezincane phakathi kwawo. Ukuze kube sobala, kufana nokuthi isango elivalwe kahle livuleka kancane. Ngalezo zikhala, imithi yomdlavuza ingaya ngqo kumaseli omdlavuza. Akumangalisi yini?
Ake sibheke ezinye zezinzuzo zalobu buchwepheshe obusha kuthebula elingezansi.
| Isici | Incazelo |
|---|---|
| Ithagethi | Imithi iqondiswa ngqo emaseli omdlavuza wobuchopho. |
| Ukuphepha | Akulimazi izicubu zobuchopho ezinempilo. |
| Izinto | Yenziwe nge-glycine, ewusizo emzimbeni. |
| Okubolayo | Ngokuhamba kwesikhathi, iyancibilika emzimbeni ngaphandle kokulimaza. Asikho isidingo sokwenza olunye ukuhlinzwa ukuze isuswe. |
| Ukulawula | Odokotela bangalawula ukuthi le divayisi kufanele isebenze isikhathi esingakanani. |
Ukusetshenziswa kabanzi kobuchwepheshe be-ultrasound
Lobu buchwepheshe be-ultrasound abuyona into entsha emkhakheni wezokwelapha. Sivame ukuzwa ngabo kuma-scan ezinsana. Kodwa manje busetshenziswa okungaphezu kwalokho. Ngokusho kukaDkt. Neal Kassell, omunye wochwepheshe abasemuva kobuchwepheshe, kufana "nokusebenzisa ingilazi yokukhulisa ukuze ugxilise imisebe yelanga futhi ushise iqabunga." Lokho kusho ukuthi amandla angaqondiswa ngokunembile kakhulu, kuphela kulokho okufunwayo. Ngakho-ke akulimazi izicubu ezinempilo ezizungezile.
Odokotela manje sebeyazi izindlela ezingaphezu kuka-30 ezahlukene zokuxhumana nezicubu besebenzisa ubuchwepheshe be-ultrasound, uma kuqhathaniswa nezindlela ezi-5 kuphela eminyakeni eyishumi edlule.
Ngalolu lwazi, kunethemba lokuthi lobu buchwepheshe bungasetshenziswa hhayi ekwelapheni umdlavuza wobuchopho kuphela, kodwa futhi nasezifweni zezinzwa ezifana ne-Alzheimer's kanye ne-Parkinson's, umdlavuza we-pancreatic kanye ne-prostate okunzima ukuwulapha, ngisho nokulutha kwezidakamizwa.
Libukeka kanjani ikusasa lalobu buchwepheshe?
Kumelwe sikhumbule ukuthi lokhu kusesesigabeni socwaningo. Ososayensi bakuhlolile lokhu emagundwini futhi babone imiphumela ephumelela kakhulu. Lapho benikezwa umuthi, amathumba ancipha futhi isikhathi sokuphila kwezilwane saphindeka kabili. Ngisho nangemva kwezinyanga eziyi-6, akukho miphumela emibi ebikiwe. Okulandelayo, ithimba lihlela ukuhlola ukuphepha nokusebenza kwayo ezingulubeni.
Usosayensi oholayo owathola lokhu, uThanh Nguyen, unethemba lokudala into efana ne-patch ngeziningi zalezi zimila ezincane esikhathini esizayo. Ngemuva kwalokho kuzokwenzeka ukuqondisa nokwelapha izingxenye ezahlukene zobuchopho ngesikhathi esisodwa. Mhlawumbe le ndlela ingasetshenziswa ukubhubhisa noma yimaphi amangqamuzana omdlavuza asele ngemva kokususwa kwesimila sobuchopho ngokuhlinzwa.
Umlayezo Wokuya Nawe Ekhaya
- Ukufakelwa okungabola okuxoxwe ngakho kulesi sihloko kuwubuchwepheshe besimanje obuthembisayo kakhulu bokwelapha umdlavuza wobuchopho.
- Lokhu kuhilela ukusebenzisa amaza e-ultrasound ukuvula okwesikhashana isithiyo segazi nobuchopho , okuvimbela imithi yokulwa nomdlavuza ukuthi ingangeni ebuchosheni.
- Lokhu kusesesigabeni sokucwaninga , futhi kuzothatha isikhathi ngaphambi kokuba kusetshenziswe kubantu.
- Lokhu kungasetshenziswa esikhathini esizayo njengesengezo noma okunye kokwelashwa okukhona njengokuhlinzwa kobuchopho, i-chemotherapy, kanye nokwelashwa ngemisebe.
- Uma wena noma othile omaziyo enenkinga ngesimo somdlavuza, xoxa ngaso njalo nodokotela wakho.
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