Uma udokotela wakho ekutshela noma othandekayo wakho ukuthi udinga ukuthola umjovo obizwa ngokuthi i-Blinatumomab ukuze welaphe i-leukemia, kuvamile ukuzizwa wesaba kancane, ukhathazekile, futhi unelukuluku. Luhlobo luni lomuthi? Lulwa kanjani nomdlavuza? Yini okudingeka siyazi? Ngibhala le ncazelo ukuze ngiphendule imibuzo eminingi efana nale ongase ube nayo engqondweni yakho. Ake sixoxe ngazo zonke lezi zinto ngayinye ngayinye.
Kalula nje, iyini i-Blinatumomab?
I-Blinatumomab (uzoyithola ingaphansi kwegama lomkhiqizo i-BLINCYTO) umuthi okhethekile osetshenziselwa ukwelapha i-leukemia , uhlobo lomdlavuza wegazi. Ayifani nomuthi ojwayelekile we-chemotherapy. Umuthi othuthuke kakhulu.
Kalula nje, lo muthi usebenza ngokukhuluma nesimiso somzimba wakho sokuzivikela , usivuse, futhi usisize sithole futhi sibhubhise amangqamuzana omdlavuza. Kufana nokubonisa izivikelo zomzimba wethu izitha ezifihliwe (amangqamuzana omdlavuza) bese sizitshela ukuthi, "Lalelani, bahlasele." Kwezokwelapha, sibiza lolu hlobo lwemithi ngokuthi ama-antibody e-monoclonal . Okusho ukuthi, iphrotheni eyenzelwe ukuhlasela isisulu esithile kuphela.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala ukwelashwa
Ukuze ukunikeze ukwelashwa okungcono kakhulu nokuphephile, kubalulekile ukuthi udokotela wakho azi umlando wakho wezempilo ophelele. Ngakho-ke, uma kukhona okulandelayo okukusebenzelayo, qiniseka ukuthi utshela udokotela wakho ngaphandle kokuzibamba .
- Uma uke welashwa ngemisebe ebuchosheni: Uma uke welashwa ngemisebe endaweni ethile yobuchopho bakho ngaphambili, qiniseka ukuthi uyakhuluma ngakho.
- Ukutheleleka Kwamanje: Uma okwamanje unesifo esithile , njengomkhuhlane, ukukhwehlela, umkhuhlane, noma ukutheleleka komgudu womchamo.
- Isifo sesibindi: Uma unesifo esihlobene nesibindi.
- Izinkinga zesimiso sezinzwa: Uma wake waba nokuxhuzula esikhathini esidlule, uma uzizwa sengathi ulahlekelwa yinkumbulo, uma unezinkinga ezifana nobunzima bokukhuluma, noma uma ulahlekelwa yibhalansi yakho lapho uhamba.
- Uma uhlelelwe ukuthola umuthi wokugoma: Uma uhlela ukuthola noma yimuphi umuthi wokugoma maduze.
- Ukungezwani komzimba: Uma une-allergy kulo muthi we-Blinatumomab noma yimuphi omunye umuthi, ukudla, noma idayi.
- Uma uzama ukukhulelwa noma ukhulelwe: Lokhu kubaluleke kakhulu uma ukhulelwe noma uhlela ukuba nomntwana. Lo muthi ungalimaza kakhulu ingane ngesikhathi sokukhulelwa.
- Uma uncelisa:Uma ungumama oncelisa ingane.
Ngingakunika kanjani lo muthi?
Leli akulona iphilisi oligwinyayo. I-Blinatumomab umuthi ofakwa emthanjeni . Ngokuvamile unikezwa esibhedlela noma emtholampilo, ngaphansi kokuqashwa okuseduze kwabasebenzi bezokwelapha.
Lokhu akuvamile ukujova kanye kuphela. Kunikezwa esikhwameni esincane (isikhwama sokufaka) futhi kunikezwa njengesixazululo sikasawoti esifakwa kancane kancane emzimbeni wakho esikhathini samahora angama-24. Ngale ndlela, ukwelashwa kungaqhubeka izinsuku eziningana.
Ngaphambi kokuthi uqale ukwelashwa ngakunye, uzonikezwa incwajana yolwazi ekhethekile (i-MedGuide) ngalo muthi. Kubaluleke kakhulu ukuwufunda nokuwuqonda ngokucophelela isikhathi ngasinye.
Ngisho nezingane ezincane (kusukela ezinyangeni ezi-1 ubudala) zinikezwa lo muthi kwezinye izimo ezikhethekile. Kodwa-ke, isinqumo senziwa udokotela wezingane.
Kuthiwani uma ngengozi uthatha umuthi omningi kakhulu?
Lokhu kunikezwa esibhedlela, ngakho-ke amathuba okuba lokhu kwenzeke mancane kakhulu. Kodwa-ke, uma ucabanga ukuthi kungenzeka ukuthi uphuze kakhulu lo muthi, shayela iNational Poisons Information Centre eColombo National Hospital ngokushesha . Noma, iya e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Kuthiwani uma ngiphuthelwa yiseshini yokwelashwa?
Kubaluleke kakhulu ukuqeda umjikelezo wakho wokwelashwa ngqo. Ungaphuthelwa yinoma yiziphi izikhathi zokwelashwa nganoma yisiphi isizathu. Uma ngesizathu esithile ungakwazi ukuza esibhedlela ngosuku oluhleliwe, shayela ithimba lakho lezokwelapha ngokushesha bese ubazisa.
Eminye imithi engase ihlangane nalo muthi
Kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini kanye nemithi yamakhambi), njengoba eminye imithi ingase ihlangane ne-Blinatumomab.
| Izidakamizwa/izinto ezingaba yinkinga | Incazelo elula |
|---|---|
| Imithi yokugomela igciwane ephilayo | Gwema ukuthola imijovo yegciwane eliphilayo (isib. isimungumungwane, ukhunta) ngenkathi uthatha lo muthi. Lo muthi ushintsha amasosha omzimba wakho, ngakho-ke ungase uthole izifo ezivela kule mijovo. |
| I-Cyclosporine | Lezi futhi ziyimithi evimbela amasosha omzimba. Iseluleko sezokwelapha siyadingeka ngaphambi kokuzisebenzisa ndawonye. |
| I-Warfarin | Uma uthatha lo muthi ovimbela ukujiya kwegazi, ukusebenza kwawo kungashintsha nge-Blinatumomab. |
Lolu hlu aluphelele, ngakho tshela udokotela wakho ngayo yonke imithi oyithathayo.
Izinto okufanele uziqaphele kakhulu ngesikhathi sokwelashwa
Ithimba lakho lezokwelapha lizokuqapha eduze ngenkathi uthatha lolu hlobo lokwelashwa, kodwa kubalulekile futhi ukuthi unakekele umzimba wakho.
Qaphela ngezifo ezithathelwanayo.
Lo muthi ungathinta ukusebenza kwesimiso sakho somzimba sokuzivikela, okungase kwandise ingozi yakho yokuthola izifo. Ngakho-ke, uma uba nezimpawu zomkhuhlane njengomkhuhlane , ukubanda, umphimbo obuhlungu, kanye nokukhwehlela , ungaziphilisi futhi wazise ithimba lakho lezokwelapha ngokushesha. Nciphisa ukuvakashela kwakho izindawo lapho abantu begula khona.
Ukuhlolwa kwegazi
Ngesikhathi sokwelashwa, kuzodingeka ukuthi uhlolwe igazi njalo (ukuhlolwa kwegazi) ukuze uhlole amazinga egazi lakho.
Ukushayela nokusebenzisa imishini
Lo muthi ungathinta ibhalansi yakho, isikhathi sokusabela, kanye nekhono lokwenza izinqumo . Ngakho-ke, gwema ukushayela noma ukusebenzisa imishini esindayo uze wazi kahle ukuthi lo muthi ukuthinta kanjani. Ukuze unciphise ingozi yokuba nesiyezi noma ikhanda elibuhlungu, sukuma ngokushesha, kungaba lapho uhleli noma ulele phansi. Ukuphuza utshwala kungenza le miphumela emibi ibe mibi kakhulu.
Ukukhulelwa nokuncelisa (okubaluleke kakhulu)
Kudingeka uqaphele kakhulu ngalokhu. Ukukhulelwa ngenkathi uthatha lo muthi futhi emahoreni angu-48 ngemuva komthamo wokugcina kungabangela ukukhubazeka okukhulu kokuzalwa komntwana.
- Ngaphambi kokuqala ukwelashwa, uzohlolwa ukuqinisekisa ukuthi awukhulelwe.
- Kubalulekile ukusebenzisa uhlobo lokuvimbela inzalo oluthembekile phakathi nesikhathi sonke sokwelashwa kanye namahora angu-48 ngemva kokwelashwa. Khuluma nodokotela wakho ngalokhu bese ukhetha indlela efanele kakhulu.
- Gwema ukuncelisa ngokuphelele ngenkathi uthatha lo muthi futhi emahoreni angu-48 ngemuva komthamo wokugcina.
Yimiphi imiphumela emibi engingayithola?
Njenganoma yimuphi umuthi onamandla, i-Blinatumomab ingabangela imiphumela emibi. Eminye iyingozi futhi kufanele ibikwe ngokushesha. Eminye ivame ukungabi yimbi kakhulu, kodwa uma iqhubeka, kufanele utshele udokotela wakho .
| Imiphumela emibi kakhulu okufanele uyibike kudokotela wakho ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo. |
| I-Cytokine Release Syndrome | Umkhuhlane, ukubanda, ukukhathala okukhulu, ukulahlekelwa yisifiso sokudla, isicanucanu, ikhanda elibuhlungu, isiyezi, ukuquleka, ubunzima bokuphefumula, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile. Lokhu kungaba ukusabela okunamandla emuthini. |
| Ukutheleleka | Umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, amanxeba angapholi, izifo zomgudu womchamo, kanye nobuhlungu bomzimba. |
| Ukulimala kwesibindi | Ubuhlungu ohlangothini olungaphezulu kwesokudla lwesisu, ukulahlekelwa yisifiso sokudla, isicanucanu, indle enombala okhanyayo, umchamo ophuzi noma onsundu omnyama, ukuphuzi kwesikhumba noma amehlo, kanye nokukhathala okukhulu. |
| Izinkinga zesistimu yezinzwa | Ubuhlungu ezithweni zomzimba, ukungazweli, ubuthakathaka, izinguquko zokubona, ukudideka, ubunzima bokukhuluma, ukulahlekelwa yibhalansi, ubunzima bokuhamba, ukuxhuzula. |
| I-Pancreatitis | Ubuhlungu obukhulu esiswini esingaphezulu, obuphuma emhlane. Ubuhlungu obuba bubi kakhulu lapho udla noma uthinta isisu, umkhuhlane, isicanucanu, nokuhlanza. |
| Isifo se-Tumor Lysis (TLS) | Isimo esibangelwa ukubhujiswa okusheshayo kwamangqamuzana omdlavuza. Isicanucanu, ukuhlanza, isifo sohudo, ukwehla kokukhishwa komchamo, umchamo omnyama, ukukhathala okukhulu, ukudideka, ukudikiza kwemisipha, ubuhlungu bamalunga, kanye nokushintsha kwesilinganiso senhliziyo. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Ikhanda elibuhlungu | Kungase kube khona ikhanda elibuhlungu elijwayelekile. |
| Ukuvuvukala komzimba | Ukuvuvukala kwamaqakala, izandla, noma izinyawo. |
| Ukuthuthumela | Ukuqhaqhazela okungalawuleki kwezitho zomzimba, njengezandla nezinyawo. |
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma uhlangabezana nanoma yini engavamile noma engakhululekile, khuluma nodokotela wakho ngayo.
Umlayezo Wokuya Nawe Ekhaya
- I-Blinatumomab umuthi othuthuke kakhulu ovuselela amasosha omzimba wakho ukuze alwe ne-leukemia.
- Ngaphambi kokuqala ukwelashwa, tshela udokotela wakho yonke imininingwane yakho yezempilo, imithi oyiphuzayo, kanye nanoma yikuphi ukungezwani komzimba okungenzeka ukuthi unakho.
- Ngesikhathi sokwelashwa, qaphela kakhulu izimpawu zokutheleleka njengomkhuhlane nokukhwehlela, kanye nezimpawu ezingavamile ezihlobene nohlelo lwezinzwa (ubunzima bokukhuluma, ukuxhuzula). Uma ubona noma yini, tshela udokotela wakho ngokushesha.
- Okubaluleke kakhulu:Gwema ukukhulelwa ngokuphelele ngesikhathi sokwelashwa kanye namahora angu-48 ngemuva kokwelashwa. Qiniseka ukuthi usebenzisa izindlela zokuvimbela inzalo ezithembekile. Gwema nokuncelisa ibele phakathi nalesi sikhathi.
- Lolu akulona uhambo oludlula wedwa. Khuluma ngokukhululekile nodokotela wakho kanye nethimba lezokwelapha nganoma yimiphi imibuzo noma ukukhathazeka ongase ube nakho.
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