Uzizwa ukhathele ngaso sonke isikhathi? Uzizwa ubuthakathaka ngisho nangemva kokuhamba isikhashana? Uzizwa sengathi awunaso isifiso sokudla, futhi ubukeka uphaphathekile? Isikhathi esiningi, asizinaki kakhulu lezi zinto, sicabanga ukuthi zivamile. Kodwa-ke, kungase kube nesizathu esingathi sína ngemuva kwalokhu. Namuhla, sikhuluma ngesimo esingathi sína kodwa esingelapheka esibangelwa ukuntuleka kwe-vitamin B12. Lokhu sikubiza ngokuthi i -Pernicious Anemia .
Kalula nje, iyini i-Pernicious Anemia?
I-Pernicious Anemia ingenye yezimbangela eziyinhloko zokuntuleka kwe-vitamin B12. Uma sikhuluma iqiniso, lesi yisimo sokuzivikela komzimba . Manje ungase uzibuze ukuthi siyini isimo sokuzivikela komzimba. Kalula nje, umsebenzi oyinhloko wesimiso sethu sokuzivikela komzimba ukulwa nabahlaseli bangaphandle nokusivikela ezifweni. Kodwa-ke, kulesi simo, isimiso sethu sokuzivikela komzimba siqala ngephutha ukuhlasela amaseli ethu aphilile.
Kwenzeka into efanayo ku-Pernicious Anemia. Amasosha ethu omzimba ahlasela amaseli athile emathunjini (esiswini). Lawa maseli akhiqiza iphrotheni ekhethekile ebizwa ngokuthi i-Intrinsic Factor esiza umzimba ukuthi umunce i-vitamin B12. Uma le phrotheni ingekho, kungakhathaliseki ukuthi sidla i-vitamin B12 engakanani, ayimuncwa ngumzimba futhi iyachithwa.
I-Vitamin B12 ibaluleke kakhulu emzimbeni wethu. Ikakhulukazi, ibalulekile ekukhiqizweni kwamangqamuzana abomvu egazi, athwala umoya-mpilo egazini. Ngakho-ke, uma i-vitamin B12 ingekho, ukukhiqizwa kwamangqamuzana abomvu egazi anempilo kuyancipha. Yilokhu esikubiza ngokuthi i-anemia .
Igama elithi Pernicious Anemia lisho ukuthi “kuyingozi.” Lithola igama lalo ngoba, uma lingelashwa, lesi simo singadala umonakalo omkhulu, ongenakuguqulwa ohlelweni lwethu lwezinzwa.
Lesi simo sithinta kanjani umzimba wami?
I-anemia eyingozi ingathinta izinhlelo eziningana zomzimba.
- Uhlelo lokugaya ukudla: Isicanucanu, ukuqunjelwa, kanye nokwehla kwesisindo kungenzeka.
- Isimiso sezinzwa: Lokhu kuyingozi kakhulu. Kungabangela ubuthakathaka bemisipha, ukungakhululeki ezithweni, ukulahlekelwa yinkumbulo, ngisho nokuwohloka komqondo.
- Inhliziyo: Ungase ube nokushaya kwenhliziyo noma ukushaya kwenhliziyo okungajwayelekile.
- Impilo ejwayelekile: Ukukhathala okuqhubekayo kanye nobuthakathaka yizimpawu eziyinhloko.
Lesi simo sivame ukubonakala phakathi kweminyaka engama-60 nama-80, ikakhulukazi kubantu abadabuka eNyakatho Yurophu.
Ziyini izimpawu ze-Pernicious Anemia?
Enye yezinto eziyingqayizivele ngalokhu ukuthi kungathatha iminyaka ukuthi izimpawu zivele. Lokhu kungenxa yokuthi umzimba wethu ugcina i-vitamin B12 esibindini futhi uyisebenzise kancane kancane. Lokhu kugcinwa kungathatha cishe iminyaka emi-3-5 ukuthi kuphele. Ngisho noma kunjalo, kuthatha isikhathi ukuthi izimpawu zivele.
Njengoba amazinga e-vitamin B12 ehla, izimpawu ziba zimbi kakhulu. Ungathola umbono omuhle ngalokhu kuthebula elingezansi.
| Uhlobo lwesibonakaliso | Izinto okufanele uzibone |
|---|---|
| Izimpawu zokuqala (ngokuvamile ziphanjaniswe nesinye isifo) | |
| Uhlelo lokugaya ukudla | Uhudo noma ukuqunjelwa, ukulahlekelwa yisifiso sokudla, isilungulela. |
| Ukubukeka komzimba | Isikhumba esikhanyayo, i-jaundice encane (ukuphuzi kwamehlo noma isikhumba). |
| Ukuphazamiseka okuvamile | Isiyezi, ubunzima bokuphefumula (ukuphelelwa umoya) lapho umi noma uzivocavoca, ulimi oluvuvukele, ukubomvu, noma izinsini eziphuma igazi. |
| Izimpawu zesistimu yezinzwa ezibangelwa amazinga aphansi e-B12 ngokuhamba kwesikhathi | |
| Ingqondo nokuziphatha | Ukudideka, ukulahlekelwa inkumbulo yesikhashana, ukucindezeleka, ubunzima bokugxilisa ingqondo, ukucasuka, ukubona izinto ezingekho. |
| Izinkinga zemizwa zomzimba | Ukulahlekelwa ibhalansi, ukuba ndikindiki noma ukulahlekelwa umuzwa ezandleni nasezinyaweni. |
| Umbono | Ukubona kuyathinteka ngenxa yokuwohloka kwemizwa yamehlo. |
Zikhona yini ezinye izimbangela ze-Pernicious Anemia?
Yebo. Ngaphezu kwesimo sokuzivikela komzimba esibizwa ngokuthi i-Pernicious Anemia, umzimba ungase ungakwazi ukumunca i-vitamin B12 ngezinye izizathu.
- Ukuhlinzwa kwesisu: Uma kwenziwa ukuhlinzwa ukuze kususwe ingxenye noma sonke isisu (isib. ukuhlinzwa kwesisu ngokudlula ekukhuluphaleni), amaseli asiza ekumunceni i-vitamin B12 ayalahleka.
- Ukuhlinzwa kwamathumbu amancane: Ukususa ingxenye yamathumbu amancane kunciphisa ikhono lokumunca i-vitamin B12.
- Amabhaktheriya Amancane Asemathunjini: Esimweni esibizwa ngokuthi i- Small Intestinal Bacterial Overgrowth (SIBO) , amabhaktheriya amabi akhula emathunjini amancane futhi adle i-vitamin B12 ngaphambi kokuba imuncwe umzimba.
- Eminye imithi: Eminye imithi yesifo sikashukela, isifo sokuwa, kanye neminye imithi elwa namagciwane ingathinta amazinga e-vitamin B12.
- Ukutheleleka Ngezikelemu Ezithwala Amathe: Ukudla izinhlanzi ezingaphekiwe kahle, ezinegciwane kungabangela ukutheleleka ngezikelemu ezithwala amathe. Lezi zikelemu zidla i-vitamin B12.
- Ukudla: Abantu abadla imifino kuphela noma abalandela ukudla okusekelwe ezitshalweni bangase bangabi ne-vitamin B12 eyanele ekudleni kwabo.
- Ezinye izifo: Izifo zesistimu yokugaya ukudla njengesifo se-Celiac noma isifo sikaCrohn zenza kube nzima ukumunca i-vitamin B12.
- Izifo zama-hormone: Abantu abanezimo zokuzivikela komzimba ezifana ne -hypoparathyroidism kanye nesifo sikaGraves basengozini enkulu yokuthola i-anemia eyingozi.
Ukuthola kanjani lokhu, Dokotela?
Uma unalezi zimpawu, kubalulekile ukubona udokotela wakho. Uzokuhlola, athathe umlando wakho wezokwelapha, bese eyala ukuhlolwa okuningana ukuqinisekisa isimo.
- Ukuhlolwa kwezinga le-Vitamin B12: Lokhu kulinganisa ukuthi ingakanani i-vitamin B12 egazini.
- Inani Eliphelele Legazi (CBC): Lokhu kunganquma uhlobo kanye nobunzima be-anemia.
- Okunye ukuhlolwa kwegazi okukhethekile: Ukuhlolwa okufana nenani lama-Reticulocyte, i-LDH, i-Serum bilirubin, i-MMA, izinga le-Homocysteine njll., kunikeza ulwazi olujulile mayelana nokuntuleka kwe-vitamin B12 kanye nokusebenza komnkantsha wamathambo.
- Ukuhlolwa kwe-antibody: Lokhu kuhlolwa kwama-antibodies egazini ahlasela amaseli esiswini kanye ne-intrinsic factor.
- I-Endoscopy Ephezulu:Ikhamera efana nethubhu (i-endoscope) ifakwa ngomlomo bese kuhlolwa ulwelwesi lwesisu.
Iphathwa kanjani? Ingabe izolulama?
Kukhona ukwelashwa kwalokhu, futhi lezo yizindaba ezinhle kakhulu! Njengoba umzimba wakho ungakwazi ukumunca i-vitamin B12, udokotela wakho uzoqala ngokukubhalela imijovo ye-vitamin B12 . Le mijovo inikezwa ngqo emisipheni, ngakho-ke ingena ngqo egazini lakho ngaphandle kokudlula esiswini.
Uma amazinga akho e-vitamin B12 esebuyele esimweni esijwayelekile, ungase welulekwe ukuthi uqhubeke nokuthatha amaphilisi e-vitamin B12 anesilinganiso esiphezulu (okuthathelwa indawo yi-B12 ngomlomo). Udokotela wakho uzoqhubeka nokuqapha isimo sakho futhi alungise ukwelashwa kwakho.
Uzoqala ukuzizwa ukhululekile kakhulu ezinsukwini ezimbalwa zokuqala ukwelashwa. Kodwa-ke, kungathatha amasonto ambalwa ukuthi izimpawu zakho ziphele ngokuphelele futhi uzozizwa ungcono.
I-anemia eyingozi ayisona isifo esingelapheki ngokuphelele. Kodwa-ke, ngokuthatha i-vitamin B12 impilo yakho yonke, ungalawula izimpawu futhi uphile impilo enempilo ngokuphelele.
Kodwa khumbula, umonakalo ohlelweni lwezinzwa ungase ungalungiseki ngokuphelele ngisho noma une-vitamin B12. Ngakho-ke, kubaluleke kakhulu ukuxilonga lesi sifo bese uqala ukwelashwa kusenesikhathi.
Ngizinakekela kanjani?
Uma une-Pernicious Anemia, kuzodingeka uphuze i-vitamin B12 impilo yakho yonke, njengoba udokotela wakho ekuyalele. Kuyinto edingekayo.
Uma unesifo sokuntuleka kwe-B12 ngenxa yezinye izizathu, ukushintsha indlela odla ngayo nakho kungasiza. Ukudla okucebile nge-vitamin B12 kufaka phakathi:
- Inyama efana nenyama yenkomo, isibindi, inkukhu kanye nenhlanzi
- Amaqanda nemikhiqizo yobisi (ubisi, iyogathi, ushizi)
- Okusanhlamvu kwasekuseni okune-vitamin B12 eyengeziwe
- Imikhiqizo yesoya ene-vitamin B12 eyengeziwe
Kungumqondo omuhle ukukhuluma nodokotela wakho bese uthola iseluleko mayelana nokudla okufanele.
Umlayezo Wokuya Nawe Ekhaya
- I-anemia eyingozi uhlobo lwe-anemia olubangelwa amasosha omzimba ethu futhi olubangelwa ukuntuleka kwe-vitamin B12.
- Izimpawu ezifana nokukhathala okuqhubekayo, ukuphaphatheka, kanye nokuphelelwa umoya zingase zibe zincane ekuqaleni, kodwa zingaba zimbi kakhulu ngokuhamba kwesikhathi.
- Uma lesi simo singalashwa, singadala umonakalo omkhulu, ongenakuguqulwa ohlelweni lwezinzwa.
- Uma uqhubeka nokuba nalezi zimpawu, qiniseka ukuthi ubona udokotela wakho ngaphandle kokuthatha esinye isizathu.
- Ukwelashwa kuhilela imijovo noma amaphilisi e-vitamin B12 impilo yakho yonke. Lokhu kukuvumela ukuthi uphile impilo enempilo nejwayelekile.
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