Ingabe nawe uke waba nale nkinga ngemithambo yegazi yobuchopho bakho? (Cerebral Amyloid Angiopathy - CAA) Ake sixoxe ngalokhu!

Ngezinye izikhathi sizizwa sididekile kancane, akunjalo? Noma inkumbulo yethu ibonakala ibuthakathaka kancane. Abanye bangase bacabange ukuthi lokhu kuyinto evamile eyenzekayo njengoba sikhula. Kodwa-ke, ngezinye izikhathi lokhu kungaba okujulile kunalokho. Namuhla sizokhuluma ngento efana nale. Okusho ukuthi, ngesimo esibizwa ngokuthi `(Cerebral Amyloid Angiopathy)` noma `(CAA)`.

Kuyini `(Cerebral Amyloid Angiopathy - CAA)`?

Kalula nje, i-Cerebral Amyloid Angiopathy (CAA) yisimo lapho iphrotheni engajwayelekile inqwabelana khona emithanjeni yegazi emincane ebuchosheni bethu, okubangela ukuthi inciphe kancane kancane futhi ivuza igazi. Imbangela enkulu yalokhu ukunqwabelana kwephrotheni engajwayelekile ebizwa ngokuthi i-amyloid ezindongeni zemithambo yegazi ebuchosheni. Cabanga ngayo njengepayipi lamanzi elivalekile. Ngokuhamba kwesikhathi, le phrotheni ye-amyloid ibangela ukuthi izindonga zemithambo yegazi zibe mncane, zibe buthakathaka, futhi zonakale kalula.

Uma imithambo yegazi iba buthakathaka ngale ndlela, igazi liqala ukuvuza lingene ebuchosheni. Ngezinye izikhathi lokhu kuvuza kuncane kakhulu, njengokuthi "ama-microbleeds" . Okusho ukuthi, amaconsi amancane kakhulu egazi ayaphuma. Lawa mancane kakhulu kangangokuthi ngezinye izikhathi asiboni zimpawu. Kodwa ngezinye izikhathi lokhu kungafika "ekuphumeni kwegazi ngaphakathi kwekhanda" , okungukuthi, ukuphuma kwegazi okukhulu ngaphakathi ebuchosheni. Uma lokhu kuphuma kwegazi kwenzeka, kungalimaza izicubu zobuchopho futhi kubangele izinkinga ezinkulu.

Lesi simo, esibizwa ngokuthi "i-CAA", siphinde sabonakala njengembangela enkulu yesimo esibizwa ngokuthi "ukwehla kwengqondo" . "(Ukwehla kwengqondo)" kubhekisela ekwehleni kancane kancane kwamakhono ethu okucabanga, njengenkumbulo, ukunaka, ukucabanga, kanye namakhono okuxazulula izinkinga. Kufana nokuthi "iprosesa" yobuchopho bethu "iyehla." Ngokusho kochwepheshe, phakathi kuka-23% no-29% wabantu abaneminyaka engaphezu kuka-50 bangase babe nalesi simo "(i-CAA)" ezingeni eliphakathi noma elibi kakhulu. Lokho kusho ukuthi akuyona into engavamile kangako.

Yiziphi izimpawu ezingaba khona ze-`(CAA)`?

Izimpawu ezibonakala kulesi simo azifani kuwo wonke umuntu. Kuya ngokuthi lingakanani igazi elivuzayo ebuchosheni.

Cabanga ukuthi abanye abantu bangaba ne-"CAA" ngaphandle kwezimpawu. Isizathu ukuthi banokuvuza kwegazi okuncane kakhulu, okungabonakali ebuchosheni babo (''ukuphuma kwegazi okuthule''), okungabonakali. Kufana namanzi avuza kancane kancane emgodini omncane, kodwa hhayi ukuvuza okukhulu ngokwanele ukugcwalisa ibhakede.

Kodwa-ke, uma kukhona ukopha okukhulu ngaphakathi ebuchosheni, khona-ke izinkinga zezinzwa zingavela. Futhi, abanye abantu bathola ulwazi nge-"CAA" uma bethwetshulwa "i-MRI" ebuchosheni ukuze bathole enye inkinga.

Uma ukuphuma kwegazi kuba kubi kakhulu, kungase kube nezimpawu ezifana nalezi:

• Ikhanda Elibuhlungu Kakhulu: Akuyona ikhanda elivamile, libuhlungu kancane.
• Ukudideka : Izinto ezifana nendawo, isikhathi, nokuthi ubani okhona ziyadideka.
• Ubunzima bokukhuluma : Ukukhuluma amagama angacacile nobunzima bokusho lokho ofuna ukukusho.
• Ubuthakathaka obungazelelwe : Umuzwa osheshayo wobuthakathaka ohlangothini olulodwa lomzimba, ingalo noma umlenze.
• Ukukhubazeka kwengqondo : Inkumbulo iyawohloka, ukwenza izinqumo kuba nzima.
• Izimpawu zesifo sokuwa (Ukuquleka) : Kungafana nokukhubazeka.

Kwezinye izimo ezinzima kakhulu, umuntu angaze afike e-coma ngenxa yokopha okukhulu.

Kwenzekani ngempela uma kukhona `(CAA)`?

I-cerebral amyloid angiopathy empeleni uhlobo lwesifo sohlangothi oluphuma igazi . Uma unalesi simo, iphrotheni engajwayelekile ebizwa ngokuthi i-amyloid isuke ihlangene futhi inamathele ngaphakathi kwemithambo yegazi ebuchosheni bakho.

Eminyakeni edlule, izindonga zemithambo yegazi yakho ziya ngokuya ziba buthaka, zakha imifantu emincane noma imifantu evumela igazi ukuthi livuzele ebuchosheni bakho. Lapho igazi livuza kule mithambo yegazi, lilimaza izicubu zobuchopho.

Esikhathini esiningi, lokhu kopha kuzwakala sengathi ithayi likhipha umoya kancane kancane. Ekuqaleni, ngeke uzizwe umehluko omkhulu.

Abantu abaningi abazithathi ngokungathi sína izinto ezifana nokulahlekelwa yinkumbulo nokudideka ekuqaleni. Bangase bacabange, "O, lokhu kuyinto eyenzekayo uma ukhula." Kodwa ngokuhamba kwesikhathi, njengoba iphrotheni ye-amyloid ilimaza imithambo yegazi futhi yandisa inani legazi elivuza ebuchosheni, izimpawu ziya ziba zimbi kancane kancane.

Ingabe `(CAA)` ingadalwa ngokuzumayo?

Ngokuvamile akusheshi lokho. Kodwa-ke, kungenzeka kuphela uma uzuza izinguquko ezithile zofuzo ezibangela lesi sifo. Isibonelo, uhlobo oluvame kakhulu lwesifo sofuzo semithambo yegazi (i-CAA) esidluliselwa ngofuzo yisifo sohlangothi esibi, esisongela ukuphila.

Lezi zimpawu zokuqala zokushaya kwenhliziyo ezinzima. Ngisho noma zisinda ekushayweni yisifo sohlangothi, kamuva zingaba ne -dementia , isifo sokuwa , kanye nokushaya kwenhliziyo okuphindaphindiwe okungalimaza ubuchopho. Iningi labantu abanalolu hlobo lwe-CAA oluzuzwe njengefa bafa zingakapheli iminyaka eyi-10 benazo izimpawu. Kodwa kufanele futhi ukhumbule ukuthi i-CAA ezuzwe njengefa ayivamile .

Yiziphi izizathu zokwakheka kwe-`(CAA)`?

Ochwepheshe abakayazi imbangela eqondile, kodwa ucwaningo luthole ukuthi izinto ezilandelayo zingandisa ingozi:

• Isifo sika-Alzheimer: Abantu abanesifo sika-Alzheimer banamathuba amaningi okuba nalesi sifo. Lokhu kungenzeka ngoba zombili lezi zifo zihilela iphrotheni i-amyloid.
• Isizwe:Ucwaningo lubonisa ukuthi lesi simo sivame kakhulu phakathi kwamaqembu athile ezinhlanga. Isibonelo, ezinye izifundo ziphakamisa ukuthi i-CAA ivame kakhulu kubantu abamhlophe. Kodwa-ke, lesi akusona isimo esivamile, futhi kudingeka ucwaningo olwengeziwe.
• Umfutho wegazi ophakeme: Umfutho wegazi ophakeme nawo uyisici esanda ingozi ye-CAA ngokubeka ingcindezi eyengeziwe kule mithambo yegazi.

Uyibona kanjani kahle `(CAA)`?

Lena yingxenye enzima kakhulu. Ayikho indlela yokuqinisekisa lesi sifo ngokuqiniseka okungu-100% ngesikhathi umuntu esaphila. Okuwukuphela kwendlela yokuqinisekisa lokhu ukuthatha izicubu zobuchopho ngemva kokufa bese uzihlola ngaphansi kwe-microscope. Okusho ukuthi, ngokuhlolwa kwesidumbu.

Kodwa-ke, yize kungenakwenzeka ukuqinisekisa i-"CAA" ngaphambi kokufa, odokotela bangenza "ukuxilongwa okucatshangelwayo" ukuthi kungenzeka ukuthi lesi sifo sikhona. Lokhu kwenziwa ngokusebenzisa:

• Ukuskena kobuchopho nge-Magnetic Resonance Imaging (MRI): Lokhu kungabona amahlule amancane egazi (ama-microbleeds) ebuchosheni.
• Ukuskena kwe-`(PET)` (i-Positron Emission Tomography scan) nge- (Amyloid tracer labeling) : Lokhu kungasetshenziswa ukubona ukuthi iphrotheni ye-`(amyloid)` ifakiwe yini ebuchosheni.

Kusekelwe olwazini olutholwe kulezi zivivinyo ukuthi odokotela banquma ukuthi bangaba yi-CAA noma cha.

Ingabe kukhona ukwelashwa kwe-`(CAA)`?

Ngokudabukisayo, ayikho ikhambi eliqinisekile lalokhu noma indlela yokukuvimbela ukuthi kungenzeki.

Ngakho-ke, uma ukuhlolwa kwakho kubonisa ukuthi ungase ube nalesi simo, udokotela wakho uzozama ukunciphisa amathuba akho okuphuma igazi ebuchosheni, ukuphuma kwegazi okuningi, noma ukuphuma kwegazi okukhona kube kubi kakhulu. Lokho kusho ukulawula izimpawu zakho nokulawula isimo ukuthi singabi sibi kakhulu.

Ukunikeza izibonelo ezimbalwa:

• Ukulawula umfutho wegazi ophakeme: Umfutho wegazi ophakeme ongapheli wandisa ingozi yokopha ebuchosheni. Uma ukuhlolwa kubonisa izimpawu ze-"CAA" futhi nawe unomfutho wegazi ophakeme, udokotela wakho uzoqapha impilo yakho iyonke kanye nomfutho wegazi. Bangase batuse nemithi kanye nezinguquko zendlela yokuphila (ukudla, ukuvivinya umzimba) ukuze wehlise umfutho wegazi lakho.
• Qaphela ngemithi yokunciphisa igazi: Uma une-CAA futhi uthatha imithi yokunciphisa igazi, njenge-warfarin noma i-aspirin, ngenxa yesifo sokujiya kwegazi, kungenza ubuchopho bakho buphume igazi kakhulu. Uma unalesi simo, udokotela wakho angakutshela ukuthi uyeke ukuthatha imithi yokunciphisa igazi futhi angaphakamisa ezinye izindlela eziphephile zokuvimbela ukujiya kwegazi. Yingakho kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo.

Ungaphila isikhathi esingakanani ne-`(CAA)`?

Lona umbuzo obuzwa abantu abaningi. Kodwa-ke, kunzima ukunikeza impendulo eyodwa. Uhluka kakhulu kuye ngesimo sakho.

Ubudala bakho, uhlobo lwezimpawu zakho zamanje, impilo yakho iyonke, kanye nezinye izimo zezokwelapha ezandisa ingozi yakho yokopha okukhulu kobuchopho (isib. isifo sikashukela, i-cholesterol ephezulu) konke kuthinta ukuthi uzophila isikhathi esingakanani.

Udokotela wakho ungumthombo ongcono kakhulu wolwazi mayelana nokuthi yini ongayilindela. Uzokwazi isimo sakho esithile futhi uzokwazi ukukweluleka ngokufanele.

Ngingazinakekela kanjani?

Uma uthola ukuthi une-CAA (i-CAA), kubalulekile ukuzinakekela. Ukuqonda ingozi yakho kuyinto engcono kakhulu ongayenza ukuze uzinakekele.

Isibonelo, uma ukuhlolwa kubonisa ukuthi une-"(CAA)" kodwa awunazo izimpawu ezinkulu, udokotela wakho angakweluleka ngezindlela zokuvimbela umfutho wegazi ophakeme noma ukugwema imithi yokunciphisa igazi engadingekile. Lokhu kufaka phakathi:

• Hlola umfutho wegazi lakho njalo bese uwulawula njengoba udokotela wakho encoma.
• Yidla ukudla okunempilo.
• Vivinya umzimba njalo.
• Uma ubhema, yeka.

Kufanele ngimbone nini udokotela?

Uma izimpawu zakho ziba zimbi kakhulu, bona udokotela wakho ngokushesha.

Isibonelo, i-CAA ingathinta amakhono akho okukhumbula nokucabanga. Uma wena noma othile omaziyo enezinkinga zokukhumbula (ukukhohlwa amagama, ukulahleka), noma uma uqala ukudideka noma unenkinga yokukhuluma kunangaphambili, udokotela wakho angase afune ukukuhlola ukuthi kukhona yini ukopha okusha kobuchopho. Ngakho-ke ungazinaki lezi zinguquko.

Kufanele ngiye nini egumbini lezimo eziphuthumayo?

Lokhu kubaluleke kakhulu. Uma izimpawu ziba zimbi ngokuzumayo, njengekhanda elibuhlungu, ukudideka, ubunzima bokukhuluma, noma ukulahlekelwa ukwazi, kufanele uye esibhedlela ngokushesha.

Ngoba kungenzeka ukuthi uke waba nesifo sohlangothi esibangelwa ukopha, isifo sohlangothi esibangelwa ukopha okungabangela ukulimala kobuchopho noma ukufa unomphela. Ukuthola ukwelashwa ngokushesha ngemva kwesifo sohlangothi kubaluleke kakhulu ukuze kusindiswe izimpilo futhi kuncishiswe ukukhubazeka kwesikhathi eside.

Nazi ezinye izimpawu eziyisixwayiso zesifo sohlangothi:

• Ukugoba kolunye uhlangothi lobuso: Uhlangothi olulodwa lobuso alukwazi ukuphakanyiswa kahle uma umomotheka.
• Ubuthakathaka engalweni eyodwa: Uma ucelwa ukuba uphakamise zombili izingalo phambili, enye ingalo iyehla.
• Ubunzima bokukhuluma: amagama ayaxaka, awukwazi ukuqonda okushiwoyo.
• Ikhanda elibuhlungu elinzima ngokuzumayo: Ikhanda elibuhlungu elingakaze libonwe empilweni yakho.

Uma ubona noma yiziphi zalezi zimpawu, ungachithi isikhathi uye esibhedlela ngokushesha.

Yimiphi imibuzo okufanele ngiyibuze udokotela?

Uma ukuhlolwa kwakho kubonisa ukuthi kungenzeka ukuthi unayo (i-CAA), kuvamile ukuba nemibuzo eminingi. Nansi eminye imibuzo ongayibuza udokotela wakho:

• Yini ngempela eboniswa yi-MRI noma ama-PET scan ami?
• Ingabe nginayo igazi ngaphakathi ebuchosheni bami? Lingakanani?
• Kungenzeka yini ukuthi lokhu kuphuma kwegazi kuzoqhubeka nokuba kubi kakhulu?
• Iyini ingozi yami yokuba nesifo sohlangothi?
• Lokhu kuzothinta kanjani inkumbulo yami kanye nekhono lami lokucabanga?
• Yiziphi izinguquko zendlela yokuphila okudingeka ngizenze?
• Yimiphi imithi engingayithatha? Ingabe inemiphumela emibi?
• Kufanele ngiphinde ngihlolwe futhi nini?

Ingabe i-`(CAA)` nayo i-`(Dementia)`?

Cha, azifani. Kodwa kukhona ukuxhumana phakathi kwalezi ezimbili. I-Cerebral Amyloid Angiopathy ingabangela ukushaywa yigazi . Lezi zishayo zilimaza amangqamuzana obuchopho, okungaholela ekuwohlokeni kwemithambo yegazi . I-Dementia yisimo esonakalisa imisebenzi yobuchopho efana nenkumbulo, ukucabanga, ulimi, kanye nokwahlulela. Ngakho-ke, i-CAA ingaba yimbangela eyodwa yokuwohloka kwemithambo yegazi.

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

I-Cerebral Amyloid Angiopathy (CAA) yisimo esingaba yingozi lapho iphrotheni i-amyloid ifakwa emithanjeni yegazi yobuchopho, okubangela ukopha.

• Izimpawu zokuqala zingaba zicashile kakhulu - njengokulahlekelwa inkumbulo okuncane, ukukhohlwa amagama. Kodwa lokhu kungaba kubi kakhulu ngokuhamba kwesikhathi.
• Akukho ukwelashwa okuqondile kwalokhu, kodwa izimpawu zingalawulwa futhi isimo singalawulwa. Ukulawula umfutho wegazi nokulandela indlela yokuphila enempilo kubaluleke kakhulu.
• Uma unezimpawu ezisolisayo (ikakhulukazi ukulahlekelwa yinkumbulo, ukudideka, izinguquko ezisheshayo zezinzwa), funa iseluleko sezokwelapha ngokushesha.
• Ukuqaphela i-(CAA) kuzokusiza wena nabathandekayo bakho ukuthi nibhekane nalesi simo.

Ngiyethemba ukuthi lolu lwazi luzokusiza. Uma unemibuzo, ungangabazi ukukhuluma nodokotela wakho.

i - angiopathy ye-cerebral amyloid, i-CAA, ukopha ebuchosheni, ukuphuma kwegazi okuncane, ukopha kwegazi ngaphakathi kwekhanda, ukwehla kwengqondo, isifo sohlangothi lokopha, iphrotheni ye-amyloid, i-dementia, i-Alzheimer's, umfutho wegazi ophakeme, i-MRI, i-PET scan, ukopha ebuchosheni, i-amyloid, ukulahlekelwa yinkumbulo, isifo sohlangothi