Ukuqonda "Ukuvinjelwa Kwemibhobho Yenyongo" noma I-Cholestasis - Nirogi Lanka

Wake wezwa amagama anjengokuthi "i-bile evaliwe" noma "amatshe enyongo"? Kungenzeka ukuthi wake waqaphela abantu abanamehlo noma isikhumba esiphuzi. Wake wazibuza ukuthi lezi zimo empeleni ziyini noma ukuthi kungani zenzeka? Namuhla, sizokhuluma ngesimo esaziwa ngokwezokwelapha ngokuthi i-Cholestasis . Ungakhathazeki, sizokuchazela sona eNirogi Lanka.

Kuyini i-Cholestasis?

Kalula nje, i-cholestasis yenzeka lapho ukugeleza kwe-bile kusuka esibindini sakho kunciphisa noma kuyeka ngokuphelele. Cabanga ngesibindi sakho njengefektri ematasa emzimbeni wakho ekhiqiza i-bile . Lolu ketshezi lubalulekile enqubweni yakho yokugaya ukudla, ikakhulukazi ekugayweni kwamafutha.

Isibindi sithumela inyongo ohlelweni lwakho lokugaya ukudla ngenethiwekhi yamapayipi amancane abizwa ngokuthi ama-bile ducts ( ama-bile ducts ). Amanye ala ma-ducts atholakala ngaphakathi kwesibindi (intrahepatic), kanti amanye angaphandle (extrahepatic). Le nethiwekhi ixhumanisa isibindi sakho, ama-pancreas , kanye namathumbu amancane ukuze kwakheke uhlelo lwenyongo .

Manje, cabanga ukuthi kwenzekani uma kukhona ukuvaleka noma kuphi kule nethiwekhi. Njengombhobho wamanzi ovalekile, i-bile ayikwazi ukugeleza kahle. Iqala ukubuyela emuva emapayipini nasezithweni ezizungezile, okuhlanganisa nesibindi sakho. Lokhu kwakheka kungalimaza izicubu futhi kuphazamise imisebenzi ebalulekile. Ngaphezu kwalokho, i-bile engaguquki ingavuza egazini lakho, okuyinto enobuthi emzimbeni wakho. Lokhu kungaholela ezimpawini ezingakhululekile futhi, ngokuhamba kwesikhathi, ezinkingeni ezahlukene zempilo. I-Cholestasis ingaba inkinga yesikhashana noma isimo esingamahlalakhona, esiqhubekayo.

Lokhu kuthinta kanjani umzimba wakho?

I-Cholestasis ithinta umzimba wakho ngezindlela eziningana:

Imiphumela yesikhashana:

Umthelela osheshayo uba sezitho zomzimba ezingaphakathi kwesimiso sakho senyongo. Ukuqongelela kwenyongo kungabangela ukuthi isibindi sakho, inyongo, i-pancreas, noma imisele yenyongo ivuvuke futhi ivuvuke ( ukuvuvukala ). Lokhu kuvame ukuholela ebuhlungwini besisu kanye nesicanucanu. Ngaphezu kwalokho, ungase ube sengozini enkulu yokutheleleka.

Ngenxa yokuthi amathumbu amancane awatholi inyongo eyanele, umzimba wakho awukwazi ukugaya amafutha ngendlela efanele. Lokhu kungaholela ekuvuvukeni, ekugayeni ukudla okunamafutha amaningi kanye nohudo.

Imiphumela yesikhathi eside:

Uma lesi simo siqhubeka, kungase kuvele izinkinga ezinkulu kakhulu:

• Ukuqongelela kwenyongo egazini kungaholela ku -jaundice , ebonakala ngokuphuzi kwesikhumba namehlo, kanye nomchamo onombala omnyama.
• Ezinye iziguli zizwa ukulunywa okukhulu (i-pruritus) , okubangelwa usawoti we-bile ocasula imizwa esikhumbeni.
• Ukuvuvukala kwesibindi okungapheli kungaholela ekuqhekekeni okungapheli, isimo esaziwa ngokuthi i-cirrhosis .
• Ungase ube nobunzima bokumunca amavithamini ancibilika emafutheni, okungukuthi amavithamini A , D, E, kanye no-K . Lokhu kungaholela ekungondleki kahle, okungase kuphazamise ukukhula kwezingane kakhulu.

Inothi Elibalulekile:

Uma uhlangabezana ne-cholestasis ngesikhathi sokukhulelwa (i-Obstetric Cholestasis), ibeka izingozi ezinkulu kumama nakumntwana, okuhlanganisa i-preeclampsia, ukubeletha ngaphambi kwesikhathi, kanye nokuzalwa kwengane isishonile. Uma ukhulelwe futhi ubona lezi zimpawu, sicela ufune usizo lwezokwelapha oluphuthumayo noma uvakashele isibhedlela esiseduze nawe ngokushesha.

Yiziphi izimbangela eziyinhloko?

Kunezimbangela eziningi ze-cholestasis. Ngokuvamile, zingahlukaniswa ngezinhlobo ezimbili eziyinhloko:

Ziyini izimpawu ze-cholestasis?

Izimpawu ezivame kakhulu ongase uzibone zifaka:

• I-Jaundice: Ukuphuzi kwesikhumba sakho kanye nokumhlophe kwamehlo akho kuvame ukuba uphawu lokuqala lokuthi isibindi sakho asisebenzi kahle. Lokhu kwenzeka ngenxa yokuqongelela kwe-bilirubin, umbala otholakala ku-bile, egazini lakho. Ungase futhi uqaphele umchamo wakho uba phuzi noma nsundu njengoba uzama ukukhipha i-bilirubin eningi.
• Indle enombala okhanyayo: Njengoba indle ingakwazi ukufinyelela emathunjini akho, indle yakho ingashintsha ukubukeka kwayo. Ngenxa yokuthi indle iyadingeka ukuze igaye amafutha, amafutha angadluliselwa esithweni, okwenza sibukeke siphuzi, sinombala wobumba, noma simhlophe. Ngaphandle kwe-bilirubin ukuze sinikeze umbala waso onsundu ojwayelekile, indle ibonakala ilula futhi ingase intante noma ibe nephunga elibi elinamandla ngendlela engavamile.
• Ukuqunjelwa (Ukuluma): Uphawu oluvame kakhulu lwe-cholestasis. Lokhu kulunywa okukhulu kubangelwa usawoti we-bile oqoqana egazini lakho futhi uvuselele uhlelo lwakho lwezinzwa oluseceleni. Okuphawulekayo ukuthi lokhu kulunywa kwenzeka ngaphandle kokuqubuka okubonakalayo. Ukuzwela kuyahlukahluka kumuntu nomuntu; kungase kugxile ezintendeni nasematheni akho, noma ungase ukuzwe kuwo wonke umzimba wakho.

Ngaphezu kwezimpawu eziyinhloko, ungase ubhekane nezinye izimpawu kuye ngokuthi imbangela eyinhloko ye-cholestasis ibangelwa yini:

• Ubuhlungu besisu
• Isicanucanu nokuhlanza
• Ukukhathala

Kutholakala kanjani?

Uma ubhekene nezimpawu ze-cholestasis, udokotela wakho cishe uzoqala ngokuhlola isampula yegazi lakho.

• Ukuhlolwa kwegazi: Lokhu kuhlola amazinga aphezulu e-bilirubin kanye nosawoti we-bile. Udokotela wakho uzolinganisa nama-enzyme esibindi, okuhlanganisa i-alkaline phosphatase (ALP), i-gamma-glutamyl transferase (GGT), kanye namazinga e-cholesterol, ukusiza ekutholeni imbangela eyinhloko.
• Ukuhlolwa kwezithombe: Uma ukuhlolwa kwegazi kubonisa inkinga, udokotela wakho uzosebenzisa izithombe ukuhlola uhlelo lwakho lwe-biliary. Ukuhlolwa okulula, okungangenisi ukungcola okufana ne-ultrasound yesisu noma i-CT scan kuvame ukuba yisinyathelo sokuqala sokubheka ukuvinjelwa ngokomzimba emigudwini ye-bile noma ukuvuvukala kwezitho zomzimba.
• Ukuhlolwa kokuhlola: Ukuze kutholakale imbangela eqondile futhi kutholakale ukwelashwa okungcono kakhulu, kungadingeka uphenyo oluningiliziwe. Lokhu kungafaka phakathi i-biopsy yesibindi, lapho kuthathwa khona isampula encane yezicubu ukuze kuhlaziywe elebhu, noma i -ERCP (Endoscopic Retrograde Cholangiopancreatography) , evumela odokotela ukuthi babone, baxilonge, futhi baphathe izinkinga ezingaphakathi kwe-bile duct yakho ngesikhathi esisodwa.

Iphathwa kanjani?

Ukwelashwa kwe-cholestasis kuncike ngokuphelele emsukeni wembangela.

• Izimbangela ezibukhali: Ezinye izimo kulula ukuzilawula. Isibonelo, udokotela wakho angase ashintshe imithi ebangela inkinga, anikeze ama-antibiotic noma ama-antiviral ezifo, noma asebenzise izinqubo ze-endoscopic njenge-ERCP ukuze asuse ukuvaleka kwe-bile duct.
• Izimbangela Ezingamahlalakhona: Izimo ezihilela isifo sesibindi sesikhathi eside zingaba nzima kakhulu. Nakuba ezinye izimo zesibindi ezingamahlalakhona zingenakwelashwa noma ziguqulwe (njenge-cirrhosis), unganciphisa kakhulu ukuqhubeka kwesifo ngokudla okunempilo, ukuzivocavoca njalo, nokugwema ngokuphelele utshwala. Ithimba lakho lezokwelapha lizogxila ekuphatheni izimpawu zakho nokuvimbela ezinye izinkinga.

Izinhlelo zokwelapha zingafaka:

• Ukudla Okunomsoco: Ukulungiswa kokudla kanye nezithasiselo zokudla ukuze kulungiswe ukungondleki kahle noma ukuntuleka kwamavithamini.
• I-Ursodeoxycholic acid: Nakuba ivame ukusetshenziswa ukuncibilikisa amatshe enyongo, lo muthi ungasiza futhi ngokwandisa ukukhiqizwa kwenyongo nokunciphisa umthelela wosawoti wenyongo ongaphezulu egazini lakho.
• I-Naltrexone: Lo mphikisi we-opioid ngezinye izikhathi unqunyelwe ukuphatha ukulunywa okukhulu ngokuvimbela izindlela zemizwa ezivuselelwa yi-bile acid.
• I-Cholestyramine: Lo muthi usebenza ngokubopha kusawoti we-bile emathunjini, okusiza ekuwususeni ngendle yakho.