Ake sifunde ngomdlavuza ongajwayelekile ohlotshaniswa nokukhulelwa? (Choriocarcinoma)

Wake wezwa ngegama elithi Choriocarcinoma? Leli kungaba igama elisha kuwe. Empeleni lona umdlavuza ongavamile kakhulu futhi ongathi sína. Kodwa ungakhathazeki, ake sixoxe ngakho ngokuningiliziwe. Lesi simo sivame ukuhlotshaniswa nokukhulelwa. Ngakho-ke, kubaluleke kakhulu ukuqaphela lokhu.

Kuyini i-Choriocarcinoma?

Kalula nje, i-choriocarcinoma uhlobo lomdlavuza olwakheka esibelethweni sakho noma emaqanda futhi lungasakazeka ngokushesha okukhulu. Kunezinhlobo ezimbili eziyinhloko zalokhu futhi.

Uhlobo oluvame kakhulu lwe -choriocarcinoma oluvela ngesikhathi sokukhulelwa lubizwa ngokuthi i-Gestational Choriocarcinoma . Lokhu kungokweqembu elibizwa ngokuthi i-Gestational Trophoblastic Disease (GTD). I-GTD yisimo somdlavuza esikhula emaseli avela ku-placenta ngesikhathi sokukhulelwa. Njengoba wazi, i-placenta yingxenye ebaluleke kakhulu yomzimba enikeza umntwana umoya-mpilo kanye nokudla okunomsoco ngentambo yesisu.

I-Choriocarcinoma ivame ukubonakala kwabesifazane abake bakhulelwa i-molar . Ukukhulelwa kwe-molar yisimo lapho kuvela khona i-hydatidiform mole esibelethweni esikhundleni sengane ngenxa yephutha ekukhuleni kweqanda nesidoda. Kungavela futhi ngemva kokukhulelwa kwe-ectopic , ukuphuphuma kwesisu, noma ngisho nokubeletha okuvamile.

Into eyingozi kakhulu ngalo mdlavuza ukuthi ungasakazeka ngokushesha kwezinye izingxenye zomzimba. Isibonelo:

• Amaphaphu
• Ingqimba yemisipha yesibeletho
• Ama-lymph node
• Isibindi noma izinso
• Ubuchopho
• Imithambo yegazi

Kodwa izindaba ezinhle ukuthi ezimweni eziningi, lesi simo se-choriocarcinoma singelapheka ngokuphelele nge-chemotherapy .

Yiziphi izinhlobo ze-choriocarcinoma?

Njengoba sishilo ngaphambili, kunezinhlobo ezimbili ze-choriocarcinoma:

1. I-Gestational Choriocarcinoma: Lolu uhlobo oluvame kakhulu. Lungakhula ngesikhathi sokukhulelwa noma ngemva nje kokukhulelwa.

2. I-Choriocarcinoma Engeyona Eyokukhulelwa: Lokhu kungathinta kokubili abesilisa nabesifazane. Luhlobo lwesimila segciwane. Kwabesifazane, singavela ezinqeni noma olwelwesini lwesibeletho, kodwa asihlobene ne-placenta. Kwabesilisa, singavela emasendeni.

Sivame kangakanani lesi sifo?

I-Gestational Choriocarcinoma (GCT) ibangela cishe u-5% wamacala e-GTD. Ngisho nasezweni elifana ne-United States, amacala e-GTD ayenzeka cishe ku-0.1% wabo bonke ukukhulelwa. Ngakho-ke, cabanga ngalokhu: I-GCT ayivamile nakakhulu. Iyenzeka ngaphansi kokukhulelwa okungu-7 kwabangu-100,000 e-United States. Lokhu kusho ukuthi kuyisimo esingavamile kakhulu naseSri Lanka.

Ziyini izimpawu ze-Choriocarcinoma?

Umuntu one-choriocarcinoma, ikakhulukazi lowo osanda kukhulelwa, angase abe nezimpawu ezifana nalezi:

• Ukopha okungajwayelekile kwesitho sangasese sowesifazane
• Ubuhlungu be-pelvic

Uma umdlavuza usakazekela kwezinye izingxenye zomzimba, kungase kube nezinye izimpawu, njenge:

• Uma isakazekela emaphashini: ukukhwehlela, ubunzima bokuphefumula.
• Uma isakazekela esithweni sangasese sowesifazane: ukopha okukhulu, ukuphuma okungavamile, kanye namaqhubu esithweni sangasese sowesifazane.
• Uma isakazekela ebuchosheni: Ukuquleka, ikhanda elibuhlungu.
• Uma isakazekela ezinso noma esibindini: ubuhlungu besisu.

Yiziphi izizathu zalokhu?

I-Choriocarcinoma yenzeka lapho amangqamuzana akha i-placenta (abizwa ngokuthi ama-trophoblast) eba nomdlavuza. Ingakhula ekuqaleni kokukhulelwa noma kamuva. Cishe abantu abangu-50% abathola i-choriocarcinoma bake baba nokukhulelwa kwe-molar ngaphambilini. Ukukhulelwa kwe-molar kwenzeka lapho kukhula isikhwama esigcwele uketshezi ngaphakathi kwesibeletho esikhundleni sengane esanda kuzalwa.

Ku-choriocarcinoma engeyona eyesibeletho, amaseli kuma-ovari, amasende, noma esibelethweni aqala ukukhiqiza i-hormone ebizwa ngokuthi i-human chorionic gonadotropin (hCG) . Uma ibukwa ngaphansi kwe-microscope, la maseli abukeka afana namaseli e-trophoblast.

Ikhula ngokushesha kangakanani i-Gestational Choriocarcinoma?

Akukho sikhathi esibekiwe sokuthi lokhu kwenzeke. Kungavela ezinyangeni noma ngisho neminyaka ngemva kokukhulelwa. Kodwa-ke, kubhekwa njengohlobo lomdlavuza olusakazeka ngokushesha kakhulu futhi olunolaka.

Yiziphi izinto ezibangela lesi simo?

Noma ubani okhulelwe (kungakhathaliseki ukuthi ukukhulelwa kwesisu, ukukhulelwa okungavamile, ukukhulelwa okuqediwe, noma ukubeletha okuvamile) angathola i-choriocarcinoma. Kodwa-ke, usengozini enkulu uma uke waba nokukhulelwa kwe-molar.

Ezinye izinto eziyingozi yilezi:

• Ukuba ngaphansi kweminyaka engama-20 noma ngaphezulu kweminyaka engama-40 ngesikhathi sokukhulelwa.

Yiziphi izinkinga zalesi simo?

I-Choriocarcinoma ingaba yingozi uma ingelashwa, njengoba lolu hlobo lomdlavuza lusakazeka ngokushesha okukhulu.Kodwa ngokwelashwa, abantu abaningi bangaphumelela ekukhululweni noma ekwelapheni ngokuphelele. Njengakweminye imidlavuza, ukutholwa kusenesikhathi kanye nokwelashwa kuyindlela engcono kakhulu yokuthola imiphumela.

Itholakala kanjani i-Choriocarcinoma?

Udokotela usebenzisa lezi zivivinyo ukuxilonga i-choriocarcinoma:

• Ukuhlolwa kwesinqe noma ukuhlolwa ngokomzimba kwenziwa ukuze kuhlolwe noma yiziphi izigaxa.
• Kwenziwa ukuhlolwa kwegazi ukuhlola izinga le-hCG (i-human chorionic gonadotropin). Abantu abane-choriocarcinoma banamazinga aphezulu kakhulu e-hCG.
• Ukuhlolwa kwegazi ukuhlola ukusebenza kwesibindi nezinso.
• Inani Eliphelele Legazi (i-CBC).
• I-ultrasound yesitho sangasese sowesifazane.
• I-CT scan (i-Computed Tomography - i-CT scan).
• Ukuskena kwe-MRI (I-Magnetic Resonance Imaging - i-MRI).
• I-X-ray yesifuba.

Lezi zivivinyo zingasiza nodokotela ukuthola ukuthi umdlavuza ususakazeke yini.

Iphathwa kanjani i-Choriocarcinoma?

Odokotela belapha i-choriocarcinoma ngokuya ngesigaba sayo. Isigaba somdlavuza yindlela udokotela ahlukanisa ngayo umdlavuza, ngokusekelwe ezicini ezifana nobukhulu besimila nokuthi ngabe sisakazeke ngaphandle kwesibeletho. Impilo yakho iyonke kanye nezintandokazi zakho zomuntu siqu nazo ziyacatshangelwa lapho kwakhiwa uhlelo lokwelashwa.

Ukwelashwa okuyinhloko kwe-choriocarcinoma yi-chemotherapy. I-Chemotherapy uhlobo lomuthi obulala amangqamuzana omdlavuza.

Abanye abantu bangadinga ukuhlinzwa kwesisu, ukwelashwa ngemisebe, noma inhlanganisela yalezi zindlela zokwelapha.

Ngemva kokwelashwa, udokotela wakho uzoqhubeka nokukuhlola ukuthi ngabe kukhona yini ukuphindaphinda kwesifo (izivivinyo zokulandelela).

Ingabe umdlavuza we-choriocarcinoma ungelapheka?

Yebo, i-choriocarcinoma ingelapheka. Ngokuvamile ingelapheka nge-chemotherapy. Uma itholakala kusenesikhathi, ngaphambi kokuba isakazekele kwezinye izingxenye zomzimba, amathuba okwelashwa aphezulu kakhulu.

Ukuphulukiswa kungaba nzima kakhulu kulezi zimo:

• Uma uke waphathwa nge-chemotherapy ngaphambilini kodwa yehluleka.
• Uma lesi sifo sivela ngemva kokukhulelwa noma ukubeletha isikhathi esigcwele.
• Uma izinga le-hCG lingaphezu kuka-40,000 mIU/ml (amayunithi angama-milli-international nge-milliliter) ngaphambi kokuqala ukwelashwa. (i-hCG iyi-hormone ekhiqizwa yi-placenta ngesikhathi sokukhulelwa).
• Uma ube nezimpawu izinyanga ezingaphezu kwezine ngaphambi kokuqala ukwelashwa noma uma ukhulelwe.

Ingabe i-choriocarcinoma ingavinjelwa?

Cha, i-choriocarcinoma ayinakuvinjelwa. Kodwa-ke , uma uke waba nokukhulelwa kwe-molar, kubaluleke kakhulu ukukhuluma nodokotela wakho ngengozi yakho ye-choriocarcinoma.

Ungaphila isikhathi esingakanani ne-Choriocarcinoma?

I-Choriocarcinoma isesigabeni sayo sokuqala inombono omuhle. Izinga lokusinda kwabantu abane-choriocarcinoma yokukhulelwa esengozini encane cishe liyi-100%. Izinga lokusinda kwabantu abane-choriocarcinoma yokukhulelwa esengozini enkulu liyi-94%.

I-choriocarcinoma engeyona i-gestational (uhlobo olungahlobene nokukhulelwa okungavamile/izicubu ze-placenta) inesimo esibi kakhulu. Futhi ayizweli kakhulu kumakhemikhali kumakhemikhali, okusho ukuthi i-chemotherapy ingase ingasebenzi kahle ekubulaleni amangqamuzana omdlavuza.

Ingabe i-Choriocarcinoma yeSigaba sesi-4 ingelapheka?

Isigaba sesi-4 se-choriocarcinoma sisho ukuthi umdlavuza ususakazekele kwezinye izingxenye zomzimba wakho, njengobuchopho bakho noma isibindi. Odokotela bakho bazokhuluma nawe ngalokhu. Kodwa-ke , kusenethuba lokuthi lesi sifo sizophela.

Ngingaba nomunye umntwana uma ngine-choriocarcinoma?

Mhlawumbe. Abantu abaningi bakwazile ukuthola abantwana futhi ngemva kokwelashwa kwe-choriocarcinoma. Kuya ngokuthi uxilongwe yini. Uma ufuna ukuba nezingane, khuluma nodokotela wakho ngakho. Bangakunikeza ukwelashwa okungcono kakhulu.

Kufanele ngimbone nini udokotela?

Uma unesifo sokuphuma kwegazi esingavamile esithweni sangasese sowesifazane noma ubuhlungu besisu esingezansi, ikakhulukazi uma uke waba nokukhulelwa kwe-molar ngaphambili, qiniseka ukuthi ubona udokotela.

I-Choriocarcinoma umdlavuza ongavamile kodwa oyingozi. Kuvamile ukuzizwa ucindezelekile uma uthola ukuxilongwa okunje. Kodwa-ke, isibikezelo se-choriocarcinoma sivame ukuba sihle kakhulu. Khuluma nodokotela wakho nganoma yiziphi izinkinga noma imibuzo ongase ube nayo. Bakhona ukuphendula imibuzo yakho futhi bakunikeze ukwelashwa okungcono kakhulu.

Izinto ezibaluleke kakhulu okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

• I-Choriocarcinoma umdlavuza ongavamile futhi osakazeka ngokushesha ongahlotshaniswa nokukhulelwa.
• Labo abake bakhulelwa i-molar basengozini enkulu.
• Qaphela izimpawu ezifana nokopha okungajwayelekile kwesitho sangasese sowesifazane kanye nobuhlungu besisu esingezansi.
• Lesi simoIngelapheka kakhulu nge-chemotherapy.
• Ukutholwa kusenesikhathi kanye nokwelashwa kubaluleke kakhulu.
• Uma unemibuzo noma izimpawu, funa iseluleko sezokwelapha ngokushesha. Ungakhathazeki, odokotela bakulungele ukukusiza.

I- Choriocarcinoma, umdlavuza, ukukhulelwa, i-placenta, i-chemotherapy, ukukhulelwa kwe-molar, i-hCG