Kuvamile ukuzizwa ukhungathekile futhi ukhathazekile lapho wena noma othandekayo wakho etholakala enomdlavuza, ikakhulukazi i-acute leukemia. Ngezikhathi ezinjengalezi, udokotela wakho uzokhuluma nawe ngezindlela ezahlukene zokwelapha. Enye yalezo zindlela zokwelapha umuthi wokugomela obizwa ngokuthi i-Clofarabine. Igama lomkhiqizo wayo yi-Clolar. Namuhla, ake sixoxe ngalo muthi, ukuthi wenzani, nokuthi yini okudingeka uyiqaphele.
Uhlobo luni lomuthi oluyiClofarabine?
Kalula nje, i-clofarabine umuthi olwa namaseli omdlavuza. Lo muthi usetshenziswa, ikakhulukazi, ezimweni ze-leukemia ebukhali. Amaseli omdlavuza emzimbeni wethu ayahlukana futhi akhule ngokushesha kakhulu. Lo muthi ubambezela ukukhula kwalawo maseli omdlavuza futhi ulawula ukusabalala kwawo . Lokhu kuyingxenye yokwelashwa komdlavuza (i-chemotherapy).
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala lo muthi
Ukuze ithimba lakho lezokwelapha likunikeze ukwelashwa okungcono kakhulu nokuphephile, kubalulekile ukuthi bazi imininingwane ephelele yesimo sakho sempilo. Ngakho-ke, ngaphambi kokuqala ukwelashwa nge-clofarabine, qiniseka ukuthi utshela udokotela wakho uma unezinye zezimo ezilandelayo:
- Uma unesifo sokopha noma isimo lapho igazi lakho lingavimbi kalula.
- Uma okwamanje unegciwane elifana nomkhuhlane, ukukhwehlela, noma umkhuhlane.
- Uma unesifo sezinso .
- Uma wake waba nokusabela kokungezwani komzimba ne-clofarabine noma yimuphi omunye umuthi, ukudla, noma idayi .
- Uma ukhulelwe noma uhlela ukukhulelwa maduze .
- Uma ungumama oncelisayo .
Ungamfihli udokotela lolu lwazi, ngoba lonke lolu lwazi lubaluleke kakhulu ekuphepheni kwakho.
Uzonikezwa kanjani lo muthi?
Lokhu akulona iphilisi noma isiraphu ongayithatha uye nayo ekhaya. Inikezwa esibhedlela noma emtholampilo kuphela. Inikezwa njengomjovo emthanjeni ngudokotela noma umhlengikazi oqeqeshiwe.
Odokotela ngezinye izikhathi banikeza lo muthi ezinganeni ezincane njengonyaka owodwa ubudala, kodwa bakwenza ngokucophelela okukhulu kanye nezinyathelo zokuphepha ezikhethekile.
Yini okufanele uyenze uma umthamo wemithi ukhushuliwe?
Njengoba lokhu kunikezwa esibhedlela, amathuba okuthi umthamo ungathathwanga aphansi kakhulu. Kodwa-ke, uma uzizwa sengathi uphuze ngokweqile nganoma iyiphi indlela noma uma uhlangabezana nanoma yiziphi izimpawu, yazisa ithimba lezokwelapha ngokushesha. Esimweni esiphuthumayo, ungashayela iNational Poisons Information Centre eNational Hospital eColombo . Noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Kuthiwani uma ngiphuthelwa umthamo wemithi?
Kubaluleke kakhulu ukuthatha lo muthi ngezinsuku ezihleliwe nangezikhathi ezihleliwe. Uma ungakwazi ukuya esibhedlela ukuyothola umthamo wakho ngosuku oluhleliwe, ungaweqi. Shayela udokotela wakho ngokushesha umtshele. Bazokutshela ukuthi wenzeni ngokulandelayo.
Eminye imithi engase ihlangane nalo muthi
Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyithathayo, hhayi nje leyo oyinikezwe udokotela wakho, kodwa futhi nemithi yokunciphisa izinhlungu ethengiswa ngaphandle kwemithi kadokotela, amavithamini, amakhambi, nanoma yini enye oyisebenzisayo. Eminye imithi ingasebenzisana ne-clofarabine, ibangele imiphumela emibi engafuneki noma ishintshe indlela imithi esebenza ngayo.
Ngezansi kunezibonelo ezimbalwa nje. Lolu hlu aluphelele.
| Isigaba sezidakamizwa | Izibonelo |
|---|---|
| Ama-painkiller kanye nama-fever reduction | Ama-NSAID afana ne-Acetaminophen, i-Aspirin, i-Ibuprofen, ne-Naproxen |
| Imithi yesifo senhliziyo kanye nomfutho wegazi ophezulu | I-Amiodarone, i-Methyldopa, ama-diuretics ahlukahlukene |
| Imithi yokwehlisa i-cholesterol | I-Atorvastatin, i-Simvastatin |
| Imithi yokutheleleka okuhlukahlukene (ama-antibiotic/ama-antifungal) | I-Amphotericin B, i-Fluconazole, i-Ketoconazole, i-Acyclovir, i-Amoxicillin, i-Gentamicin, i-Tetracycline, i-Vancomycin, i-Rifampin |
| Umuthi wesifo sokuwa/sokuquleka | I-Carbamazepine, i-Phenytoin, i-Valproic acid |
| Eminye imithi yokulwa nomdlavuza kanye nemithi yokuvimbela amasosha omzimba | I-Cisplatin, i-Cyclosporine, i-Methotrexate |
Izinto okufanele uziqaphele lapho uthatha umuthi
Ithimba lezokwelapha lizokuqapha ngokucophelela ngenkathi uthatha lo muthi, kodwa kubalulekile futhi ukuthi unake umzimba wakho.
- Ukuhlolwa kwegazi nokuqapha kwezokwelapha: Phakathi nalokhu kwelashwa, kuzodingeka ukuthi uhlolwe igazi njalo ukuze uhlole inani lamaseli egazi lakho, ukusebenza kwezinso kanye nesibindi. Ungakweqi lokhu.
- Ingozi yokopha: Lo muthi unganciphisa inani lamaseli emzimbeni wakho asiza ukujiya kwegazi lakho (ama-platelet). Lokhu kungenza kube nzima ngisho nokusikeka okuncane ukuyeka ukopha. Tshela udokotela wakho ngokushesha uma ubona noma yikuphi ukuklwebheka okungajwayelekile, amabala ansomi, izinsini eziphuma igazi, noma ukuphuma kwegazi ekhaleni .
- Ingozi yokutheleleka: Lo muthi wehlisa amasosha omzimba wakho, ngakho-ke ungase uthole kalula izifo. Uma uzwa izimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, noma ukukhwehlela , ungaziphilisi bese ushayela udokotela wakho ngokushesha. Nciphisa ukuvakashela kwakho izindawo lapho abantu begula khona.
- Ukusabela okukhulu kwesikhumba: Ngezinye izikhathi, ngisho namasonto ambalwa ngemva kokuqala umuthi, ukusabela okukhulu kwesikhumba kungenzeka. Uma ubona noma yini efana nama-blister abomvu noma onsomi esikhumbeni sakho kanye nomkhuhlane, ukuxebuka kwesikhumba, noma izilonda emlonyeni wakho, ungakushayi indiva. Funa iseluleko sezokwelapha ngokushesha.
- Ukukhulelwa nokuncelisa: Lo muthi ungabangela izinkinga ezinkulu zokuzalwa enganeni uma uthathwa ngesikhathi sokukhulelwa . Ngakho-ke, kufanele ugweme ukukhulelwa ngesikhathi sokwelashwa kanye nezinyanga eziyisithupha ngemuva kokuyeka ukwelashwa. Futhi, gwema ukuncelisa ngesikhathi sokwelashwa kanye namasonto amabili ngemuva kokuyeka ukwelashwa.
- Ukuzala: Lo muthi ungathinta ukuzala kwabesilisa nabesifazane. Lokhu kusho ukuthi ungathinta ikhono lakho lokuba nabantwana esikhathini esizayo. Uma unenkinga ngalokhu, khuluma nodokotela wakho ngaphambi kokuqala ukwelashwa.
Imiphumela emibi engase ivele ngenxa yalo muthi
Njenganoma yimuphi umuthi, i-clofarabine ingabangela imiphumela emibi. Akuwona wonke umuntu oyitholayo. Kodwa-ke, kubalulekile ukuqaphela imiphumela engaba khona.
| Umphumela ongemuhle | Lokho okuzwayo/okukubonayo |
|---|---|
| Imiphumela emibi okufanele uyibike kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi, nobunzima bokuphefumula. |
| Ukopha okungavamile | Indle emnyama noma enegazi, ukuhlanza okufana nekhofi eligayiwe, umchamo obomvu/onsundu omnyama, amabala abomvu/onsomi esikhumbeni. |
| Isifo Sokuvuza Kwe-Capillary | Ubuhlungu esiswini noma emisipheni, ukukhathala okukhulu, ukuquleka, ukwehla kokukhishwa komchamo, ukuvuvukala kwamaqakala, izandla nezinyawo, kanye nobunzima bokuphefumula. |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, amanxeba angapholi. |
| Ukulimala kwezinso | Ukwehla kokukhishwa komchamo, ukuvuvukala kwamaqakala, izandla nezinyawo. |
| Ukulimala kwesibindi | Ubuhlungu engxenyeni engenhla kwesokudla yesisu, ukulahlekelwa yisifiso sokudla, isicanucanu, ukuphuzi kwesikhumba noma amehlo, umchamo ophuzi/onsundu omnyama. |
| Isifo se-Tumor Lysis (TLS) | Isicanucanu, ukuhlanza, uhudo, ukuncipha kokuchama, ukushaya kwenhliziyo okungajwayelekile, ukudikiza kwemisipha, ukudideka. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Ikhanda elibuhlungu | - |
| Isifiso sokudla | - |
| Isicanucanu nokuhlanza | - |
| Ubuhlungu ezandleni nasezinyaweni | - |
Umlayezo Wokuya Nawe Ekhaya
- I-Clofarabine iwumuthi onamandla onikezwa ngemithambo esibhedlela ukwelapha i-leukemia.
- Ngaphambi kokuqala ukwelashwa, tshela udokotela wakho ngokuphelele ngayo yonke eminye imithi, amavithamini, kanye nokungezwani komzimba okuthathayo.
- Ngesikhathi sokwelashwa, uma ubona noma yiziphi izimpawu zokopha okungajwayelekile, ukutheleleka (umkhuhlane, ukukhwehlela), noma izinguquko ezinkulu zesikhumba, funa iseluleko sezokwelapha ngokushesha.
- Gwema ukukhulelwa ngenkathi uthatha lo muthi kanye nezinyanga eziyisithupha ngemuva kokuyeka. Gwema nokuncelisa.
- Khuluma ngokukhululekile nodokotela wakho noma ithimba lezokwelapha nganoma yimiphi imibuzo, ukwesaba, noma ukukhathazeka ongase ube nakho. Bakhona ukukusiza.
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