Ingabe umzimba wakho uyakhula futhi ubuso bakho buyaphenduka njengenyanga egcwele? Ake sixoxe nge-'Cushing's Syndrome'!

Uke waphawula muva nje ukuthi isimo somzimba wakho sishintshile kancane, ikakhulukazi eduze komzimba wakho ongaphezulu nesisu, futhi ubuso bakho sebuyindilinga njengenyanga egcwele? Mhlawumbe unesigaxa esincane samafutha esikhula ngemuva kwentamo yakho. Lezi akuzona nje izinto ezingahleliwe. Ngemuva kwalezi zimpawu kungase kube nesifo samahomoni esibizwa ngokuthi i-Cushing's Syndrome . Ungakhathazeki, lesi yisimo esivame ukwelashwa. Ake sixoxe ngalokhu kalula, ngendlela wonke umuntu angayiqonda.

Kalula nje, iyini i-Cushing's Syndrome?

I-Cushing's Syndrome, noma i-hypercortisolism , yisimo esenzeka lapho imizimba yethu ikhiqiza i-hormone i-cortisol eningi kakhulu. Manje ungase uzibuze ukuthi iyini i-cortisol. I-Cortisol iyi-hormone ebaluleke kakhulu ekhiqizwa yizindlala ezimbili ezincane ezitholakala ngaphezu kwezinso zethu, izindlala ze-adrenal. Yenza umsebenzi omningi emizimbeni yethu.

• Ilawula umfutho wegazi .
• Ilawula amazinga kashukela egazini.
• Kunciphisa ukuvuvukala emzimbeni.
• Kuyasiza ukuguqula ukudla esikudlayo kube amandla.

Cabanga nje, konke lokhu kwenzeka uma kunesilinganiso esifanele se-cortisol. Kodwa uma le hormone iba ningi kakhulu, ukusebenza kwezinye izinhlelo emzimbeni kuqala ukuba yinkinga. Yilokho esikubiza ngokuthi i-Cushing's Syndrome. Lesi simo sivame kakhulu kwabesifazane kunabesilisa. Sivame kakhulu kubantu abaneminyaka ephakathi kuka-25 no-40.

Yiziphi izimbangela eziyinhloko ze-Cushing's Syndrome?

Kungaba nezizathu eziningana zalokhu. Ake sibheke eziyinhloko.

1. Ukusetshenziswa kwemithi (imbangela evame kakhulu)

Imbangela evame kakhulu yalesi simo ukusetshenziswa kwesikhathi eside kwemithi eningi ebizwa ngokuthi ama-glucocorticoids . Lawa avame ukubizwa ngokuthi ama-corticosteroids noma ama-steroid . Isibonelo, i-prednisoneUngathatha umuthi obizwa ngokuthi. Odokotela batusa le mithi yezimo ezifana ne-asthma, i-rheumatoid arthritis, i-lupus, noma ngemva kokufakelwa isitho. Le mithi inamandla kakhulu alawula ukuvuvukala. Kodwa-ke, uma isetshenziswa isikhathi eside, i-Cushing's Syndrome ingavela njengomphumela ongemuhle. Futhi, lesi simo singavela ngenxa yokujova okuqhubekayo kwe-steroid ezintweni ezifana nobuhlungu bamalunga kanye nobuhlungu bomhlane. Lesi simo asivamile kakhulu ngenxa yokhilimu be-steroid obusetshenziselwa izifo zesikhumba, kodwa kungenzeka.

2. Izimila ezenzeka emzimbeni

Amazinga e-cortisol anganda nasemizimbeni yethu. Isizathu salokhu izinhlobo ezahlukene zezimila ezikhula emzimbeni.

• Ama-Pituitary Tumors: Uma kuvela isimila esincane endlaleni ye-pituitary phansi kobuchopho bethu, siqala ukukhiqiza i-hormone ebizwa ngokuthi i-ACTH (i-Adrenocorticotropic hormone) . Le hormone ye-ACTH yiyo ekhombisa ukuthi ama-adrenal glands akhiqize i-cortisol . Ngakho-ke lapho i-ACTH ikhula, ukukhiqizwa kwe-cortisol nakho kuyanda ngokuzenzakalelayo. Lesi simo sibizwa nangokuthi i-Cushing's Disease .
• Izimila Zezinso: Ngezinye izikhathi isimila singakhula endlaleni ye-adrenal uqobo, engakhiqiza ngqo i-cortisol eningi.
• Izimila Ezivela Ebuchosheni: Akuvamile kakhulu ukuthi isimila sikhule endaweni lapho i-hormone ye-ACTH ingakhiqizwa khona, njengamaphaphu , i-pancreas , noma i-thyroid gland , bese siqala ukukhiqiza i-ACTH.

Lezi zimila zingaba umdlavuza noma zingabi umdlavuza.

Ziyini izimpawu zalesi sifo?

Izimpawu zingase zihluke kumuntu nomuntu, kodwa kunezinye izimpawu ezivamile ezingabonakala uma isifo sesiqhubekele phambili. Ake sibheke lezi kuthebula. Ngaphezu kwalokho, abanye abantu bangase babone amamaki okwelula ansomi noma apinki esiswini sabo, emathangeni, ezingalweni nasesifubeni. Njengoba amathambo eba buthakathaka, bangase babe nobuhlungu emhlane noma izimbambo eziphukile, hhayi kuphela lapho begoba, bephakamisa izinsimbi, kodwa nalapho bevuka esihlalweni. Uma izingane ezincane ziba nalesi simo, ukukhula kwazo kuzohamba kancane kakhulu, futhi zingase zikhuluphale kakhulu.

Udokotela usithola kanjani lesi sifo?

Kungathatha ukuvakashelwa kaningana ngudokotela wakho ukuqinisekisa ukuthi unesifo. Okokuqala, uzokuhlola ngokomzimba bese ekubuza imibuzo embalwa.

• Ziyini izimpawu zakho?
• Uqale nini ukuzibona lezi?
• Yimiphi imithi oyithathayo? (Ikakhulukazi ama-steroid)
• Uzizwa ushintsho engqondweni yakho?

Ngokusekelwe kulolu lwazi, uma kusolwa ukuthi uCushing's Syndrome unezinsolo, udokotela uzoncoma ukuhlolwa okuningana.

• Ukuhlolwa kwe-cortisol engenayo umchamo kwamahora angama-24: Kukala izinga le-cortisol emchameni oqoqwe esikhathini samahora angama-24.
• Ukuhlolwa kokucindezela i-Dexamethasone: Iphilisi le-steroid elinomthamo ophansi linikezwa cishe ngo-11 ebusuku, bese kwenziwa ukuhlolwa kwegazi ngakusasa ekuseni ukuze kubonakale ukuthi umzimba usakhiqiza i-cortisol engakanani.
• Izinga le-cortisol yamathe ebusuku: Lilinganisa amazinga e-cortisol kusampula yamathe ethathwe ebusuku.

Uma lezi zivivinyo ziqinisekisa ukuthi une-Cushing's Syndrome, isinyathelo esilandelayo ukuthola imbangela . Ukuze wenze lokhu, uchwepheshe angenza ezinye izivivinyo eziningana. Isibonelo, izivivinyo zegazi ukuhlola amazinga e-ACTH hormone, ama-CT noma ama-MRI scan.

Yiziphi izindlela zokwelapha lokhu?

Indlela yokwelapha incike ekutheni yini ebangela isimo sakho.

• • Uma imbangela kuyimithi yama-steroid: Udokotela wakho uzoqala ukunciphisa kancane kancane umthamo wakho wama-steroid njengoba esinye isimo sakho sezokwelapha (isib. i-asthma, i-arthritis) silawulwa.

Okubaluleke kakhulu: Ungayeki ukuthatha ama-steroid ngokuzumayo ngaphandle kweseluleko sikadokotela wakho. Ukwenza kanjalo kungabangela imiphumela emibi kakhulu.

• Uma imbangela kuyi-tumor: Kungase kudingeke ukuhlinzwa ukuze kususwe i-tumor. Ngezinye izikhathi, ukwelashwa ngemisebe kungase kunikezwe ngaphezu kokuhlinzwa.
• Ezinye izindlela zokwelapha: Uma ukuhlinzwa noma ukwelashwa ngemisebe kungaphumeleli, imithi inganikezwa ukulawula ukukhiqizwa kwe-cortisol. Kodwa-ke, le mithi ingaba nemiphumela emibi, ngakho-ke kufanele ithathwe ngaphansi kokuqashwa ngudokotela.

Ungayishintsha kanjani indlela yokuphila kanye nokudla kanye nokwelashwa?

Ngesikhathi ulashwa, ukulungisa indlela ophila ngayo kanye nokudla kwakho kungakusiza kakhulu ekulawuleni izimpawu zakho.

• Yidla ukudla okuhle:
• Yidla ukudla okucebile nge -calcium kanye ne-vitamin D. Lesi simo senza amathambo abe buthaka. Ubisi, iyogathi, ushizi, imifino eluhlaza, kanye nenhlanzi encane (enamathambo) kuhle.
• Nciphisa ukudla okune- sodium eningi kanye namafutha/amafutha . Lokhu kungaholela ekucindezelekeni kwegazi okuphezulu kanye nokukhuluphala.
• Lawula ubuhlungu:Izinto ezinjengokugeza ngamanzi ashisayo, ukubhucungwa umzimba kancane, kanye nokwenza i-water aerobics kungasiza ekunciphiseni ubuhlungu bemisipha.
• Impilo yengqondo: Lesi simo singaba buthakathaka. Khuluma nomndeni wakho nabangani ngalokhu. Cela usizo lwabo. Uma kudingeka, funa usizo lomeluleki. Ungacela isiqondiso kudokotela wakho.

I-Cushing's Syndrome, i-cortisol, ama-steroid, ama-hormone, umfutho wegazi ophakeme, isifo sikashukela, ukuwohloka komzimba, ubuso benyanga, i-buffalo hump, i-pituitary gland, i-adrenal gland, izimpawu ze-Cushing's syndrome, ukwelashwa kwe-Cushing's syndrome