Uma abantu becabanga ngesifo sikashukela, abantu abaningi bacabanga ngokujova nge-insulin. Abanye abantu bakuthola lokhu kuyesabisa futhi kuyacasula ngoba kufanele bakujove izikhathi eziningana ngosuku. Kodwa bewazi ukuthi manje kunemithi eminingana emisha, engeyona i-insulin, ejovayo yesifo sikashukela sohlobo 2? Eminye yalena idinga ukujova kanye ngesonto. Ngakho-ke namuhla, ake sixoxe kafushane ngale mithi emisha, ethuthukisiwe.
Uyini lomuthi? Usebenza kanjani?
Uhlobo lomuthi oluyinhloko noluthandwa kakhulu kulesi sigaba lubizwa ngokuthi ama-GLP-1 Receptor Agonists . Nakuba igama lingase lizwakale liyinkimbinkimbi kancane, indlela elisebenza ngayo ilula kakhulu.
Cabanga nje, kukhona i-hormone ebizwa ngokuthi "i-GLP-1" ekhiqizwa ngokwemvelo emzimbeni wethu. Uma sidla, le hormone ithumela isignali ku-pancreas yethu, ithi, "Kulungile, manje ushukela uyanqwabelana egazini, ngakho-ke khiqiza inani elidingekayo le-insulin." Le nqubo ibuthakathaka kancane kubantu abanesifo sikashukela.
Lokho okwenziwa yile mithi ejovwayo esikhuluma ngakho namuhla ukusebenza njengaleyo hormone yemvelo futhi ilethe lesi signali esiqondile. Okungukuthi:
- Kusiza ama-pancreas ukuthi akhiqize i-insulin kuphela uma amazinga kashukela egazini enyuka .
- Ilawula ukukhiqizwa kukashukela okungadingekile yisibindi.
- Kunciphisa izinga lokugaya ukudla. Lokhu kukwenza uzizwe usuthi ngisho nangemva kokudla okuncane. Lokhu kusiza ukulawula ukudla ngokweqile futhi kusiza ekunciphiseni isisindo .
Manje ake sibheke izinhlobo eziningana ezahlukene zemithi kulesi sigaba.
| I-Dulaglutide (i-Trulicity) | |
|---|---|
| Kuyini lokhu? | Lona futhi umuthi we-GLP-1. Into ekhethekile ukuthi udinga ukujovwa kanye ngesonto . |
| Ubani ozoyithatha? | Odokotela bayincoma kubantu abadala abanesifo sikashukela sohlobo lwesibili abangakwazi ukulawula ushukela wabo wegazi kahle ngezinye izindlela zokwelapha. Ingasetshenziswa yodwa noma kanye neminye imithi yesifo sikashukela (njenge-metformin). |
| Imiphumela emibi evamile | Isicanucanu, ukuhlanza, ubuhlungu besisu, ukuqunjelwa, kanye nokulahlekelwa yisifiso sokudla kungase kwenzeke ezigabeni zokuqala. Esikhathini esiningi, lokhu kuzophela zingakapheli izinsuku ezimbalwa. |
| I-Semaglutide (i-Ozempic) | |
|---|---|
| Kuyini lokhu? | Lona futhi umuthi we-GLP-1 odumile kakhulu othathwa kanye ngesonto . Abantu abaningi eSri Lanka bawazi ngegama elithi Ozempic. |
| Ubani ozoyithatha? | Inikezwa abantu abadala abanesifo sikashukela sohlobo lwesibili. Kutholakale ukuthi inezinzuzo ezengeziwe, ikakhulukazi kulabo abasengozini enkulu yesifo senhliziyo noma isifo sezinso. Odokotela bayayincoma nakubantu abakhuluphele ngoba iyasiza nasekunciphiseni isisindo. |
| Imiphumela emibi evamile | Ukucanuzela okuncane kuya kokuphakathi, ukulahlekelwa yisifiso sokudla, ubuhlungu besisu, kanti kwabanye abantu, izinkinga zamehlo (i-diabetic retinopathy) zingase zande. Ngakho-ke qaphela lapho uhlolwa amehlo. |
| I-Tirzepatide (Mounjaro) | |
|---|---|
| Kuyini lokhu? | Lona umuthi omusha futhi othuthuke kakhulu. Usebenza njenge-GLP-1 kanye nenye i-hormone ebizwa ngokuthi i-GIP. Ngakho-ke umuthi 'osebenza kabili' . Uphinde uthathwe kanye ngesonto. |
| Ubani ozoyithatha? | Inikezwa abantu abadala abanesifo sikashukela sohlobo lwesibili. Ibonisa imiphumela emihle kakhulu ekulawuleni ushukela egazini kanye nokwehlisa isisindo. |
| Imiphumela emibi evamile | Njengeminye imithi, isicanucanu, isisu esibuhlungu, ukulahlekelwa yisifiso sokudla, ubuhlungu besisu, kanye nokuqunjelwa kungase kwenzeke. |
Okubalulekile: Ukwaziswa okukhethekile ngemithi yeklasi le-GLP-1
Izifundo zezilwane zibonise ukuhlangana phakathi kwale mithi kanye nengozi eyengeziwe yomdlavuza we-thyroid ezilwaneni, njengezimpuku. Kodwa-ke, akukacaci ukuthi lokhu kuzoba njalo yini kubantu . Kodwa-ke, njengesinyathelo sokuqapha, uma wena noma othile emndenini wakho enomlando womdlavuza we-thyroid, kufanele nakanjani utshele udokotela wakho ngaphambi kokuqala lo muthi.
Esinye isidakamizwa esisebenza ngendlela ehlukile kancane
Ngaphezu kwekilasi le-GLP-1, kukhona omunye umuthi wokugoma osebenza ngendlela ehlukile.
| I-Pramlintide (i-Symlin) | |
|---|---|
| Kuyini lokhu? | Lolu uhlobo lokwenziwa lwe-hormone ebizwa ngokuthi i-Amylin, ekhiqizwa yi-pancreas yethu kanye ne-insulin. |
| Ubani ozoyithatha? | Lokhu kunikezwa abantu abanesifo sikashukela sohlobo 1 nohlobo 2 abaphuza i-insulin ekudleni . Isetshenziswa kanye ne-insulin. |
| Indlela esebenza ngayo | Uma kuthathwa ne-insulin ngaphambi kokudla, lokhu kusebenza ndawonye ukulawula ushukela egazini. Njengeminye imithi, yehlisa ijubane lokugaya ukudla futhi ikwenze uzizwe usuthi. |
| Imiphumela emibi evamile | Umphumela oyinhloko ongemuhle ukucasuka. Ukuze anciphise lokhu, udokotela uzoqala ngomthamo ophansi bese enyusa umthamo kancane kancane. Ukulahlekelwa yisifiso sokudla, ukuhlanza, ukukhathala, kanye nesiyezi nakho kungase kwenzeke. |
Uma ucabanga ngalomuthi...
Le mithi ithuthuke kakhulu futhi iyasebenza. Kodwa ayifanele wonke umuntu. Udokotela wakho kuphela onganquma ukuthi lolu hlobo lomuthi lukufanele yini. Uzokhetha ukwelashwa okungcono kakhulu ngemva kokucabangela izici eziningi ezifana nesimo sakho sempilo, uhlobo lwesifo sikashukela sakho, ubudala, nezinye izifo.
Ikakhulukazi uma uhlela ukukhulelwa noma ukhulelwe njengamanje, kufanele wazise udokotela wakho ngaphambi kokusebenzisa noma yimuphi wale mithi, njengoba kungekho zifundo ezanele okwamanje mayelana nokuthi ibathinta kanjani abesifazane abakhulelwe.
Umlayezo Wokuya Nawe Ekhaya
- Akuzona zonke izijovo zesifo sikashukela ezisebenzisa i-insulin. Manje sekukhona imithi ethuthukisiwe ethathwa kanye ngesonto, njenge-Ozempic kanye ne-Trulicity.
- Le mithi ayilawuli ushukela egazini kuphela, kodwa ingakusiza futhi unciphise isisindo ngokwenza uzizwe usuthi.
- Imiphumela emibi efana nokucanuzela kwenhliziyo, ukuhlanza, nokulahlekelwa yisifiso sokudla ivamile uma uqala ukuthatha lo muthi. Esikhathini esiningi, iyaphela ngemva kwezinsuku ezimbalwa. Kodwa uma iqhubeka noma inzima, tshela udokotela wakho.
- Ngaphambi kokuqala noma yimuphi umuthi omusha, qiniseka ukuthi utshela udokotela wakho ngezimo zakho zezokwelapha zamanje kanye nomlando wezokwelapha womndeni (ikakhulukazi umdlavuza we-thyroid).
- Unganqumi ukuthi lo muthi ukulungele yini ngokubheka i-inthanethi. Udokotela okuxilongayo kuphela okufanele athathe leso sinqumo.
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