Ingabe udokotela wakho ukunike i-Glasdegib (Daurismo) wena noma othile emndenini wakho ngomdlavuza obizwa ngokuthi i-Acute Myelogenous Leukemia? Umuthi onamandla kakhulu onegama eliyinkimbinkimbi. Ngakho-ke, lena yindlela elula kakhulu futhi enobungane yokukhuluma ngalo muthi, indlela osetshenziswa ngayo, kanye nalokho okudingeka sikuqaphele kakhulu.
Uhlobo luni lomuthi iGlasdegib?
Kalula nje, i-Glasdegib umuthi ohlasela amangqamuzana omdlavuza futhi uwavimbe ekukhuleni kwawo. Amangqamuzana omdlavuza emzimbeni wethu adinga amaprotheni akhethekile ukuze akhule. Lo muthi okwenziwa yilo muthi ukuvimba ukusebenza kwalawo maprotheni. Ngale ndlela, lapho amangqamuzana omdlavuza engakwazi ukukhula, sithola usizo olukhulu ekulawuleni umdlavuza.
Lo muthi usetshenziswa kakhulu ukwelapha uhlobo lomdlavuza wegazi olubizwa ngokuthi i-acute myelogenous leukemia. Ngezinye izikhathi, udokotela wakho angase akunike lo muthi kwezinye izimo. Udokotela wakho uzokuchazela lokhu ngokuningiliziwe.
Izinto ezibaluleke kakhulu okufanele uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Njengoba i-Glasdegib ingumuthi onamandla kakhulu, kubaluleke kakhulu ukwazisa udokotela wakho nganoma yiziphi ezinye izimo zezokwelapha onazo. Uma unezinye zezimo ezingezansi, tshela udokotela wakho ngakho ngaphambi kokuqala umuthi.
- Uma unesifo senhliziyo.
- Uma uke waba nokushaya kwenhliziyo okungajwayelekile ngaphambilini.
- Uma unomlando wezifo ezihlobene nemisipha.
- Uma unesifo sezinso.
- Uma unesifo sesibindi.
- Uma izinga lama-electrolyte egazini (isib. i-potassium, i-magnesium) liphansi kakhulu noma liphezulu kakhulu.
- Uma uke waba nokusabela kokungezwani komzimba neGlasdegib, eminye imithi, ukudla, amadayi, noma izithasiselo.
- Uma ukhulelwe, noma uhlela ukukhulelwa maduze.
- Uma ungumama oncelisayo.
Ukufihla lolu lwazi kudokotela wakho kungabeka impilo yakho engozini engadingekile. Ngakho-ke ungesabi ukukhuluma ngokukhululekile ngakho konke.
Ungayisebenzisa kanjani imithi ngendlela efanele?
Kubaluleke kakhulu ukuphuza umuthi njengoba nje udokotela emyalile, ngesilinganiso esifanele, ngesikhathi esifanele.
- Gwinya leli philisi lonke ngengilazi yamanzi. Ungaliphuli, ulichoboze, noma ulihlafune.
- Ungakuthatha lokhu noma ungakudli. Kodwa into ebaluleke kakhulu ukuthi ukuthathe ngendlela efanayo nsuku zonke.Isibonelo, uma uqala ukuyithatha ngemva kokudla, yithathe nsuku zonke ngemva kokudla. Uma uqala ukuyithatha ngaphambi kokudla, yithathe nsuku zonke ngaphambi kokudla.
- Ungalokothi uyeke ukuthatha imithi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.
- Uma unikeza izingane lo muthi, khuluma nodokotela wezingane ngawo bese uwusebenzisa kuphela ngokwemiyalelo yakhe.
- Uma ngephutha uthatha umuthi omningi kakhulu: Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital , noma uye e-Emergency Treatment Unit (ETU) eseduze.
Wenzani uma uphuthelwa umthamo?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma kungaphansi kwamahora ayi-12 ngaphambi komthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
Yiziphi izithiyo zokusebenzisa lo muthi?
I-Glasdegib ingasebenzisana neminye imithi, ngakho-ke kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo.
Ungayithathi le mithi nge-Glasdegib:
- I-Cisapride
- i-dronedarone
- i-fluconazole
- i-pimozide
- i-posaconazole
- i-saquinavir
- i-thioridazine
Le mithi ingasebenzisana ne-Glasdegib:
- Imithi yokulwa negciwane lengculazi noma ingculazi
- Eminye imithi yokwelapha izifo zesikhunta (isib. i-itraconazole, i-ketoconazole)
- Amanye ama-antibiotic (isb. i-clarithromycin)
- Eminye imithi yokwelapha ukuxhuzula (isib. i-carbamazepine, i-phenytoin)
- Eminye imithi ebangela ukushaya kwenhliziyo okungajwayelekile (elula isikhathi se-QT)
- Imithi yendabuko efana ne-St. John's Wort
- Ijusi le-Grapefruit
Lolu hlu aluphelele. Ngakho-ke nikeza udokotela wakho uhlu oluphelele lwazo zonke izidakamizwa, amavithamini, imithi yamakhambi, kanye nezithasiselo ozithathayo. Ungakhohlwa ukumtshela uma ubhema noma uphuza utshwala.
Izinto okufanele uziqaphele kakhulu lapho uthatha i-Glasdegib
- Ukuhlolwa kwegazi: Kuphoqelekile ukuthi kwenziwe ukuhlolwa kwegazi (umsebenzi wegazi) njengoba kunqunywe udokotela wakho ngenkathi uthatha lo muthi.
- Ukukhulelwa: Abesifazane kufanele bagweme ukukhulelwa ngenkathi bethatha lo muthi futhi okungenani izinsuku ezingu-30 ngemva kokuyeka umuthi. Amadoda kufanele futhi agweme ukuba nguyise wengane ngenkathi ethatha lo muthi futhi okungenani izinsuku ezingu-30 ngemva kokuyeka umuthi. Lo muthi ungabangela umonakalo omkhulu enganeni engakazalwa.
- Ukuncelisa: Ngesikhathi uthatha umuthi futhi okungenani izinsuku ezingu-30 ngemva kokuyeka.Gwema ukuncelisa umntwana.
- Ukunikela ngesidoda kanye negazi: Gwema ukunikela ngesidoda noma ngegazi ngenkathi uthatha umuthi futhi okungenani izinsuku ezingu-30 ngemva kokuyeka.
- Ukuzala: Lo muthi ungathinta ikhono lakho lokuthola abantwana. Uma unenkinga ngalokhu, khuluma nodokotela wakho.
Imiphumela emibi engase ivele ngenxa yemithi
Njenganoma yimuphi umuthi, i-Glasdegib ingaba nemiphumela emibi. Eminye idinga ukunakekelwa okusheshayo, kanti eminye ivamile.
| Umphumela ongemuhle | Incazelo |
|---|---|
| Izinto okufanele uzibike kudokotela wakho noma eMnyangweni Wezimo Eziphuthumayo (ETU) ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ubunzima bokuphefumula | Ubunzima bokuphefumula. |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, umphimbo obuhlungu, izilonda zomlomo. |
| Ubuhlungu bemisipha | Ubuhlungu obukhulu bemisipha obungachazeki. |
| Ukopha okungavamile | Indle emnyama noma enegazi; ukuhlanza into ebukeka njengekhofi elicwebezelayo; amabala abomvu esikhumbeni; ukuphuma kwegazi ekhaleni, ezinsinini, noma emehlweni; ukuphuka kwesikhumba okungavamile. |
| Izinguquko ekushayeni kwenhliziyo | Ubuhlungu besifuba, isiyezi, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuzizwa uphelelwe amandla, ukuquleka. |
| Ukukhathala okungavamile | Ukuzizwa ubuthakathaka kakhulu, ubuthakathaka noma ukhathele ngendlela engavamile. |
| Tshela udokotela wakho uma kuqhubeka noma kuyakhathaza. | |
| Shintsha ukunambitheka | Ukunambitheka kokudla kuyashintsha. |
| Ukuqunjelwa | Ubunzima bokukhipha indle. |
| Isicanucanu | Ukuzizwa sengathi uhlanza. |
| Ukuvuvukala | Ukuvuvukala kwamaqakala, izinyawo, noma izandla. |
| Ukukhathala okuvamile | Ukuzizwa ukhathele kancane. |
Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, sicela wazise udokotela wakho ngazo.
Umlayezo Wokuya Nawe Ekhaya
- Njalo thatha i-Glasdegib njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanele, nangomthamo ofanele.
- Ngaphambi kokuqala umuthi, tshela udokotela wakho ngayo yonke imithi, amavithamini, imithi yendabuko oyithathayo, kanye nanoma yiziphi izimo zezokwelapha onazo.
- Gwema ukukhulelwa, ukuncelisa, ukunikela ngegazi, kanye nokunikela ngesidoda ngenkathi uthatha lo muthi kanye nezinsuku ezingu-30 ngemva kokuyeka. Lokhu kusebenza kokubili kwabesifazane nabesilisa.
- Uma kuvela imiphumela emibi kakhulu (isib., ubunzima bokuphefumula, ukopha okungavamile, ubuhlungu besifuba), bona udokotela ngokushesha noma uye eMnyangweni Wezimo Eziphuthumayo (ETU).
- Lo muthi unikezwe wena kuphela. Ungawabelani nabanye nganoma yisiphi isizathu.
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