Cabanga nje uya kudokotela wakho ukuze ayohlolwa igazi. Ngemva kokufunda umbiko, udokotela uthi, "Izinga lakho le-cholesterol ye-LDL (embi) liphezulu kancane." Umbuzo wokuqala ofika engqondweni yakho uthi, "O, ingabe kufanele ngithathe lo muthi wokwehlisa i-cholesterol manje?" Impendulo yalokhu ayilula njengoba yayinjalo ngaphambili. Sekuyinkimbinkimbi kancane manje. Ake sifinyelele emnyombweni wakho.
Unquma kanjani ukunikeza i-statin?
Esikhathini esidlule, kwakukhona imithetho ecacile yalokhu. Uma izinga lakho le-cholesterol egazini lingaphezu kwezinga elithile, udokotela wakho angakweluleka ukuthi wenze izinguquko endleleni yokuphila bese uqala ukuthatha umuthi we-statin.
Indlela yokuphila enempilo isabalulekile. Lokho kusho ukudla ukudla okunempilo, ukunciphisa amafutha agcwele, kanye nokuzivocavoca njalo . Kodwa impendulo yombuzo wokuthi kufanele yini uthathe ama-statin ihlukile kancane manje. Lokhu kushintshe ngemuva kokuba i-American Heart Association (AHA) kanye ne-American College of Cardiology (ACC) zibuyekeze iziqondiso zazo.
Okwamanje, kuphela uma izinga lakho le-cholesterol embi (LDL) liphezulu kakhulu (190 mg/dL noma ngaphezulu) lapho uzoqala khona umuthi ngokusekelwe kulelo zinga. Ngaphandle kwalokho, udokotela wakho uzocabangela ezinye izici eziningana. Isibonelo:
- Ingabe unesifo soshukela?
- Ngokusho kwe-calculator ethile yezingozi, ingabe ingozi yakho yokuba nesifo senhliziyo noma isifo sohlangothi eminyakeni eyi-10 ezayo ingu-7.5% noma ngaphezulu?
Izinto eziningi ezinjengalezi sezicatshangelwa lapho kwenziwa isinqumo. Kodwa into eyodwa okufanele uyikhumbule ukuthi abanye odokotela abazilandeli ngqo lezi ziqondiso ezintsha. Ngakho-ke, ngaphambi kokukunikeza umuthi, udokotela wakho uzokhuluma nawe ngazo zonke ezinye izinto eziyingozi ezithinta isifo senhliziyo.
Ekugcineni, isinqumo sokuthatha i-statin yisinqumo okufanele wena nodokotela wakho nisenze ndawonye, ngakho-ke kubalulekile ukuba nolwazi oluphelele ngalokhu.
Kwenzekani ngempela ngala ma-statin?
Kalula nje, i-statin uhlobo lomuthi onciphisa i-cholesterol. Uma uthatha owodwa, amazinga akho e-cholesterol embi (LDL) angancishiswa ngo-35% kuya ku-50% noma ngaphezulu, kuye ngohlobo kanye nomthamo owuthathayo. Lokhu kunganciphisa kakhulu ingozi yakho yokuba nesifo senhliziyo noma isifo sohlangothi.
Ama-statin asebenza esibindini sethu. Avimba i-enzyme emzimbeni wethu eyenza i-cholesterol. Ngaphezu kwalokho, enza enye into ebalulekile. Okungukuthi, aqinisa ama-cholesterol deposits (i-plaque) anamathele ezindongeni zemithambo yegazi yethu futhi anciphise ukuvuvukala okwenzeka ngawo. Lokhu kubaluleke kakhulu, ngoba uma la ma-cholesterol deposits (i-plaque) eqhuma ngokuzumayo, angakha i-blood clot futhi abangele ukuhlaselwa yinhliziyo noma isifo sohlangothi.
Akukho nkinga ekunikezeni ama-statin kumuntu osevele ehlaselwe yinhliziyo noma isifo sohlangothi, ngoba le mithi iye yafakazelwa ngokuqinile ukuthi iyasiza ekuvimbeleni ukuhlaselwa yinhliziyo noma isifo sohlangothi okwesibili.
Ingabe ama-statin anemiphumela emibi?
Njenganoma yimuphi umuthi, ama-statin angaba nemiphumela emibi. Kodwa-ke, akuwona wonke umuntu oyitholayo. Ake sibheke imiphumela emibi evame kakhulu nengavamile.
| Umphumela Ongemuhle | Incazelo |
|---|---|
| Ubuhlungu bemisipha | Lona umphumela ovame kakhulu. Ungathinta abantu abangu-5% kuya ku-20% abathatha umuthi. Uma lokhu kwenzeka, khuluma nodokotela wakho ngokushintshela ku-statin ehlukile, ukunciphisa umthamo, noma ukuzama ukuwuthatha njalo ngemva kwezinsuku ezimbili esikhundleni sansuku zonke. Ungalokothi uyeke ukuthatha umuthi wakho ngaphandle kokukhuluma nodokotela wakho kuqala. |
| Ukulimala kwesibindi | Lokhu akuvamile kakhulu. Udokotela wakho uzoyala ukuhlolwa kwegazi ukuze kuhlolwe ama-enzyme esibindi sakho uma kudingeka. Uma uthatha eminye imithi (isib. iPanadol), tshela udokotela wakho ngayo. |
| Ingozi yesifo sikashukela | Ezinye izifundo zikhombisile ukuthi ukuthatha ama-statin kungabangela ukwenyuka okuncane kwamazinga kashukela egazini. Kodwa-ke, lesi simo sivame ukwenzeka kubantu asebevele besengozini enkulu yokuthola isifo sikashukela (isb., ukukhuluphala ngokweqile, i-metabolic syndrome). |
| Eminye imiphumela engavamile | Ukulahlekelwa yinkumbulo, ukudideka, kanye ne-neuropathy kuye kwabikwa kaningi kakhulu. Lokhu kuvame ukuthinta kuphela labo abathatha imithamo ephezulu. |
Yini enye okufanele uyicabangele lapho uthatha imithi?
Kungakhathaliseki ukuthi unquma ukuthatha i-statin noma cha, izinguquko zendlela yokuphila ziyadingeka. Akukho ukubalekela lokho.
Khumbula, u-80% - 90% wesifo senhliziyo ubangelwa yizinto eziyingozi esingazishintsha. Lokho kusho ukuthi sinethuba elikhulu lokuvimbela lokhu.
Lokhu kusekelwe ekudleni okuhle okunomsoco (ushukela oncishisiwe), indlela yokuphila esebenzayo, ukugwema ukubhema, kanye nokulawula isisindo somzimba wakho. Ngezinye izikhathi, uma wenza izinguquko ezibalulekile endleleni yakho yokuphila, unganciphisa inani lemithi okudingeka uyithathe. Lokhu kunciphisa nengozi yemiphumela emibi.
Nokho, kunezinto esingenakuzishintsha, njengobudala bakho kanye nezakhi zofuzo. Ngakho-ke, abanye abantu bangadinga imithi ngisho noma benendlela yokuphila enhle.
Khuluma nodokotela wakho.
Uma usenokungabaza ngalokhu, into engcono kakhulu ongayenza ukukhuluma ngokukhululekile nodokotela wakho ngakho. Mcele ulwazi olwengeziwe ngalokhu. Xoxa ngezinto ezengeziwe njengokuthi noma ubani emndenini wakho unesifo senhliziyo (umlando womndeni), ukuthi izinga lakho le-C-reactive protein (CRP) liyini, nokuthi uke waba nesifo sikashukela sokukhulelwa.
Ngezinye izikhathi, ngaphambi kokunikeza umuthi, udokotela angenza ukuhlolwa okukhethekile ukuze ahlole ukuthi i-calcium ingakanani emithanjeni yegazi.
Nakuba ama-statins eyimithi ewusizo kakhulu, awafanele wonke umuntu. Uma ungatholi imiphumela eyanele kuma-statins, noma uma ungakwazi ukuwathatha ngenxa yemiphumela emibi, kunezinye izinhlobo zemithi yokwehlisa i-cholesterol.
Into ebaluleke kakhulu ukukhuluma nodokotela wakho ngalokhu njalo. Mtshele konke okuzwayo, imibuzo yakho, nokwesaba kwakho. Uzokulalela futhi akusize wenze isinqumo esikulungele wena.
Umlayezo Wokuya Nawe Ekhaya
- Ama-statin ayimithi ephumelela kakhulu yokwehlisa i-cholesterol. Kodwa awadingeki kuwo wonke umuntu. Isinqumo sokuthatha lo muthi noma cha yinto wena nodokotela wakho okufanele niyenze ndawonye.
- Kungakhathaliseki ukuthi uphuza imithi noma cha, ukugcina indlela yokuphila enempilo (ukudla okuhle, ukuvivinya umzimba, kanye nokungabhemi) kubalulekile. Leso yisisekelo sokwelashwa.
- Umphumela ovame kakhulu we-statins ubuhlungu bemisipha. Uma uhlangabezana nanoma yikuphi kwalokhu, tshela udokotela wakho ngokushesha. Ungalokothi uyeke ukuthatha umuthi noma ushintshe umthamo ngaphandle kweseluleko sikadokotela.
- Ingozi yakho yesifo senhliziyo ayinqunywa nje kuphela amazinga akho e-cholesterol egazini (i-LDL), kodwa futhi nangezici eziningi, njengobudala bakho, umlando womndeni, kanye nezinye izimo zempilo.
- Ukuze wenze izinqumo ezinhle kakhulu ngempilo yakho, xhumana nodokotela wakho ngokukhululekile nangokwethembeka.
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