Ingabe uvame ukuthola amatshe ezinso? Noma ingabe ingane yakho iyawathola? Mhlawumbe isizathu salokhu ukuthi unekhemikhali eningi kakhulu ebizwa ngokuthi i-oxalate emchameni wakho. Lesi simo yilokho esikubiza ngokuthi i-hyperoxaluria kwisayensi yezokwelapha. Ungesabi uma uzwa leli gama, kulula kakhulu. Ake sixoxe ngalokhu ngokucacile nangendlela ongayiqonda.
Kalula nje, kuyini i-Hyperoxaluria?
I-Oxalate iyikhemikhali ekhiqizwa ngokwemvelo yimizimba yethu futhi itholakala nakwezinye zokudla esikudlayo. Ngokuvamile, izinso zethu zihlunga lawa ma-oxalate emzimbeni ngomchamo.
Kodwa-ke, kumuntu one-hyperoxaluria, inani le-oxalate emchameni wakhe liyanda kakhulu. Lokhu kungaba yingozi. Le oxalate eningi ihlangana ne-calcium emchameni ukuze kwakhiwe amatshe ezinso kanye namakristalu e-calcium oxalate .
Lawa matshe namakristalu kungalimaza izinso zakho futhi kunciphise ukusebenza kwazo. Ngokuhamba kwesikhathi, lokhu kungaholela nasekuhlulekeni kwezinso . Akukhona lokho kuphela, kodwa le oxalate eningi ingaqala nokufakwa kwezinye izicubu nezitho zomzimba.
Yiziphi izinhlobo eziyinhloko ze-Hyperoxaluria?
Kunezinhlobo ezintathu eziyinhloko kuye ngokuthi imbangela yalesi simo ibangelwa yini. Uma usuqonda lo mehluko, kulula kakhulu ukuwuqonda.
| Uhlobo lwe-hyperoxaluria | Incazelo elula |
|---|---|
| I-Hyperoxaluria Eyinhloko (PH) | Lesi yisifo esibangelwa ufuzo , okusho ukuthi sizuzwe njengefa. Okwenzekayo lapha ukuthi kukhona iphutha kuma-enzyme esibindini elibangela ukuthi umzimba ukhiqize i-oxalate ngokungalawuleki. Lesi yisifo esibi kakhulu kulezi zinhlobo ezintathu. |
| I-Enteric Hyperoxaluria | Lokhu kubangelwa yizifo zesimiso sokugaya ukudla (indlela yamathumbu).Isibonelo, abantu abanezimo ezifana nesifo sikaCrohn noma isifo samathumbu esivuvukalayo badonsa i-oxalate eningi emathunjini abo. Lesi simo singavela futhi ngemva kokuhlinzwa kokunciphisa isisindo (ukuhlinzwa kwe-gastric bypass). |
| I-Hyperoxaluria yokudla | Kulula kakhulu. Kubangelwa ukudla ukudla okuningi kakhulu okunama-oxalate amaningi . Izinto ezifana nesipinashi, ama-beet, isoya, ama-alimondi, namazambane zinama-oxalate amaningi. |
Ubani othola lokhu? Uneminyaka emingaki?
Izimpawu ze-hyperoxaluria zingavela kunoma yimuphi ubudala, kusukela ezinsaneni kuya kubantu abadala, kodwa izimpawu zivame ukuvela cishe eminyakeni emi-5.
- Abantu abane -Primary Hyperoxaluria (PH) bavame ukuba namatshe ezinso ngokuphindaphindiwe ngesikhathi sobuntwana noma sobusha (ngokuvamile ngaphambi kweminyaka engu-20). Uma lesi simo sikhula enganeni encane, singaba sibi kakhulu.
- Kuzo zombili izinhlobo zesisu kanye nezokudla , amatshe ezinso kanye nezinye izimpawu zivame ukuvela lapho umuntu ekhula.
Ziyini izimpawu zalesi simo?
Ngokuvamile uphawu lokuqala kuba amatye ezinso. Kodwa akuwona wonke umuntu othola amatye ezinso. Ake sibheke izimpawu eziyinhloko.
| Izimpawu ezivamile | |
|---|---|
| Igazi emchameni | Ukutheleleka okuphindaphindiwe kwendlela yomchamo (UTIs) |
| Ukwehluleka ukuchuma ezinganeni ezincane | |
| Izimpawu ezibangelwa amatshe ezinso | |
| |
Okubalulekile: Amatshe ezinso enganeni encane avame ukuba uphawu lwalesi simo, i-Hyperoxaluria. Ngakho-ke, uma ubona into efana nale , yisa ingane yakho kudokotela ngokushesha.
Kungani lokhu kwenzeka? Ubani osengozini enkulu?
Njengoba sixoxile ngaphambili, kunezizathu ezintathu:
- Iphutha lofuzo (i-primary hyperoxaluria): Into ezuzwa njengefa kubazali ezinganeni.
- Izifo zamathumbu: Ukumuncwa ngokweqile kwe-oxalate ngenxa yezifo zesimiso sokugaya ukudla.
- Ukudla: Ukudla ngokweqile ukudla okune-oxalate eningi.
Kunezimo eziningana ezingandisa ingozi yalesi simo:
- Uma othile emndenini wakho ene-Primary Hyperoxaluria.
- Uma uvame ukuba namatshe ezinso.
- Uma wake waba namatshe ezinso ebuntwaneni (ngisho noma kanye).
- Uma udokotela ekutshelile ukuthi i-calcium ifakwa ezinso zakho.
Yiziphi izinkinga ezingabangelwa yilokhu?
Inkinga eyinhloko neyingozi kakhulu ye-hyperoxaluria ukulimala kwezinso kanye nokwehluleka kwezinso.
Uma izinso zihluleka, azikwazi ukukhipha i-oxalate eningi eqongelela emzimbeni. Ngemuva kwalokho, lawa makristalu e-oxalate aqala ukubekwa kwezinye izingxenye zomzimba, njengamathambo, igazi, imisipha, inhliziyo, namehlo. Lesi simo sibizwa ngokuthi i-Oxalosis .
I-Oxalosis ingabangela ezinye izinkinga zempilo:
- Isifo samathambo
- I-anemia
- Izinkinga zenhliziyo namehlo
- Izinkinga ezihlobene nokukhula nentuthuko yezingane
Ngingathola kanjani ukuthi lokhu kuyatholakala?
Udokotela wakho uzokubuza ngezimpawu zakho, umlando wezokwelapha womndeni, kanye nokudla kwakho. Uzobe eseyala ukuhlolwa okuningana ukuqinisekisa ukuxilongwa.
- Ukuhlolwa komchamo: Kala amazinga e-oxalate kanye nama-enzyme emchameni.
- Ukuhlolwa kwegazi: Hlola ukusebenza kwezinso kanye nenani le-oxalate egazini.
- Ukuhlolwa kwezithombe: Ama-X-ray, i-ultrasound, noma i-CT scan ingasetshenziswa ukuhlola amatshe ezinso noma amakristalu e-calcium oxalate.
- Ukuhlolwa kwezakhi zofuzo: Uma kukhona izinsolo ze-Primary Hyperoxaluria, lokhu kuhlolwa kwenziwa ukuqinisekisa ukuthi ukuguquka kwezakhi zofuzo okubangela lokhu kukhona yini.
Ngezinye izikhathi, kungadingeka ukuthi wenze izivivinyo ezikhethekile, njenge -echocardiogram , ukuhlolwa kwamehlo, noma ukuhlolwa komnkantsha wamathambo, ukuze ubone ukuthi i-oxalate ibekwe kwenye indawo emzimbeni wakho.
Iphathwa kanjani?
Umgomo oyinhloko wokwelashwa ukunciphisa amazinga e-oxalate emzimbeni nokuvimbela nokuvikela izinso nezinye izitho ekwakhekeni kwekristalu. Ukwelashwa kuncike ohlotsheni lwe-hyperoxaluria onayo kanye nobunzima besimo.
Imithi
- Abantu abane-primary hyperoxaluria banikezwa imithamo ephezulu ye-vitamin B6 (pyridoxine) ukuze banciphise amazinga e-oxalate.
- Imithi efana ne-potassium citrate inikezwa ukuvimbela ukwakheka kwamakristalu e-calcium oxalate.
- Abantu abane-Enteric Hyperoxaluria belulekwa ukuthi bathathe izithasiselo ze-calcium ekudleni ngoba i-calcium inamathela ku-oxalate futhi isiza ukuthi ikhishwe kalula emzimbeni.
Izinguquko endleleni yokuphila kanye nokudla
- Phuza amanzi amaningi: Kubalulekile ukuphuza cishe amalitha amathathu amanzi ngosuku. Lokhu kuzosiza ekukhipheni i-oxalate eningi ngomchamo futhi kuvimbele ukwakheka kwamatshe. Lokhu kubaluleke kakhulu kuzo zonke izinhlobo.
- Ukudla: Nciphisa usawoti noshukela. Nciphisa amaprotheni ezilwane njengenyama, ubisi, namaqanda. Gwema ukudla okunama-oxalates amaningi (isipinashi, i-rhubarb, ama-beet, ushokoledi, itiye, amantongomane).
- Ukudla okune-calcium eningi: Ukwengeza ukudla okune-calcium eningi ekudleni kwakho kungasiza ekunciphiseni amazinga e-oxalate.
Kodwa khumbula, lokhu kudla akunakuba nomthelela omkhulu esimweni sofuzo esibizwa ngokuthi i-Primary Hyperoxaluria. Kudinga ukwelashwa ngemithi ngempela.
Ukuphathwa kwamatshe ezinso
Amanye amatshe ezinso azodlula ngokwawo uma uphuza amanzi amaningi. Uma engaphumi, udokotela wakho kungadingeka awasuse.
Ukufakelwa kwe-Dialysis noma ukufakelwa
Uma lesi sifo siba sibi kakhulu futhi izinso zihluleka ukusebenza, kungadingeka i-dialysis yezinso ukuze kuhlanzwe igazi. Uma isimo se-Primary Hyperoxaluria sibi kakhulu, kungadingeka ukufakelwa izinso noma isibindi.
Kufanele ubonane nini nodokotela?
Njengoba lokhu kuyisibonakaliso sokuqala samatshe ezinso, thintana nodokotela ngokushesha uma ucabanga ukuthi unamatshe ezinso, ikakhulukazi uma unalezi zimpawu:
- Ubuhlungu emhlane, ohlangothini, noma esiswini esingezansi.
- Umchamo obomvu, opinki, noma onsundu.
- Ushintsho ekuvameni noma enanini lokuchama.
- Ubuhlungu lapho uchama.
Kuvamile ukuzizwa wesaba futhi ukhathazekile uma uthola ukuthi unesifo esifana nalesi. Khuluma nodokotela wakho, umndeni wakho, nabangani bakho ngezinto ezikukhathazayo. Khumbula, ngokwelashwa okufanele, ungasiphatha kahle lesi simo futhi uhlale uphilile.
Umlayezo Wokuya Nawe Ekhaya
- I-Hyperoxaluria yisimo lapho amazinga e-oxalate aphezulu emchameni angaholela ematsheni ezinso kanye nomonakalo wezinso.
- Kunezinhlobo ezintathu eziyinhloko zalokhu: okuyinhloko, okungaphakathi, kanye nokudla.
- Uma uvame ukuba namatshe ezinso, ikakhulukazi enganeni encane, kungaba uphawu lwalesi simo. Bonana nodokotela ngokushesha.
- Ukwelashwa kuhlanganisa imithi, ukuphuza amanzi amaningi, kanye nokunciphisa ukudla okuthile.
- Ungavimbela ukulimala kwezinso ngokulandela imiyalelo kadokotela wakho ngqo.
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