Ingabe unamazinga aphezulu e-hormone prolactin emzimbeni wakho? Ake sixoxe nge-hyperprolactinemia!

Wake wazibuza ukuthi kungakanani okungenzeka ngoshintsho oluncane kwamanye ama-hormone emzimbeni wakho? Leso yisimo esizokhuluma ngaso namuhla, esibizwa ngokuthi i-hyperprolactinemia. Kalula nje, lokhu kwenzeka lapho igazi lakho line-hormone eningi kakhulu ebizwa ngokuthi i-prolactin. Le hormone ibangela kakhulu ukukhula kwebele kanye nokukhiqizwa kobisi. Lesi simo asisongeli impilo, kodwa ngezinye izikhathi singadala izinkinga ezifana nokungazali futhi siphazamise ikhono lakho lokuphila impilo evamile. Kodwa izindaba ezinhle ukuthi kukhona ukwelashwa kwaso.

Sivame kangakanani lesi simo?

Eqinisweni, lesi simo esibizwa ngokuthi i-hyperprolactinemia asivamile kangako. Sithinta abantu abangaphansi kuka-1% kuphela. Kodwa-ke, abesifazane banamathuba amaningi okuthola lesi simo kunabesilisa.

Ziyini izimpawu zalokhu?

Khumbula, abanye abantu bangase babe ne-hyperprolactinemia kodwa bangakhombisi zimpawu, noma izimpawu zingase zibe zincane kakhulu. Kodwa-ke, kunezimpawu ezimbalwa ezivamile ezingase zenzeke ngalesi simo, kungakhathaliseki ukuthi umuntu ungubani.

Izimpawu ezivamile ezithinta wonke umuntu

Lokhu kungenzeka kunoma ubani, kungakhathaliseki ubulili:

• Ubunzima bokuthola abantwana (ukungazali) : Lena inkinga eyinhloko.
• Ukwehla kwesifiso sobulili : Lokhu kusho ukwehla kwesithakazelo emisebenzini yocansi.
• Ukuncipha kobuningi bamathambo (i-osteopenia) : Lokhu kungabangela ukuba amathambo abe buthakathaka ngokuhamba kwesikhathi.
• Ukuphuma kobisi ezingonweni uma ungakhulelwe noma ungancelisi (`galactorrhea`) : Lokhu kungase kuzwakale kungavamile, kodwa futhi kuyisibonakaliso.

Izici ezithile eziqondene nabesifazane

Kwabesifazane, ngaphezu kwalezi zimpawu ezivamile, kungase kube nezinye izimpawu eziningana ezithile:

• Izinguquko emjikelezweni wokuya esikhathini ezingahlobene nokunqamuka kokuya esikhathini (ukuphela kokuya esikhathini kwanyanga zonke) : Lokhu kusho ukuthi ukuya esikhathini kuba okungajwayelekile noma kuphele ngokuphelele. Ungase ungabi nesikhathi izinyanga eziningi.
• Ubuhlungu ngesikhathi socansi ngenxa yokoma kwesitho sangasese sowesifazane : Lokhu futhi kuyinto eyenza abesifazane abaningi bangakhululeki.

Izici ezithile eziqondene namadoda

Lesi simo sithinta amadoda ngendlela ehlukile. Nazi ezinye izimpawu ezivamile abangase bazibone:

• Ukungasebenzi kahle kwe-Erectile (ED) : Lokhu kusho ubunzima bokuthola ukuqina kwe-erection.
• Ukwehla kwamazinga e-testosterone : Lena i-hormone ebalulekile emzimbeni wesilisa.
• Ukukhula kwebele (`gynecomastia`) : Ukukhula kwamabele endoda ukuze afane nawowesifazane.

Kungani lokhu kwenzeka? Yiziphi izizathu?

Kulungile, manje ake sibheke ukuthi kungani amazinga e-prolactin enyuka kanje. Kungaba nezizathu eziningana.

• I-Prolactinoma: Lesi yisona sizathu esiyinhloko. `(I-Prolactinoma)` iyisimila esingesona umdlavuza (esingesihle) (`i-adenoma`) esikhula `(i-pituitary gland)` ebuchosheni bakho. Lesi simila sibangela ukuthi i-hormone i-prolactin ikhiqizwe ngokweqile.
• Ezinye izimila ze-pituitary : Ngaphezu kwe-prolactinoma, ezinye izimila ezinkulu ngaphakathi noma eduze kwe-pituitary gland nazo zingabangela amazinga aphezulu e-prolactin. Lokhu kwenzeka ngoba lesi simila sivimba ukukhishwa kwekhemikhali ebizwa ngokuthi i-dopamine e-pituitary gland. I-Dopamine iyi-hormone elawula ukukhiqizwa kwe-prolactin.
• Imithi ethile : Ikhemikhali ebizwa ngokuthi i-dopamine yehlisa ukukhiqizwa kwe-prolactin. Ngakho-ke, noma yimuphi umuthi othinta ukukhiqizwa kwe-dopamine ungakhuphula amazinga akho e-prolactin. Eminye yale mithi ihlanganisa:
• Amaphilisi okuvimbela inzalo
• Eminye imithi yokwelapha isifo sengqondo, njenge-Risperidone ne-Haloperidol
• Imithi yokucindezeleka kwegazi okuphezulu, njenge-methyldopa kanye ne-verapamil
• Imithi yokwelapha isilungulela kanye nesifo se-gastroesophageal reflux (GERD) (isib. ama-antihistamine e-H2)
• Imithi yokucindezeleka, njengemithi yokucindezeleka ye-tricyclic kanye ne-SSRIs
• Imithi yezimpawu zokunqamuka kokuya esikhathini, njengokwelashwa nge-estrogen
• Imithi yokucanuzela nokuhlanza (imithi yokulwa nokugabha)
• Izibulala-zinhlungu eziqukethe ama-opioid

Okubalulekile : Kufanele nakanjani ukhulume nodokotela wakho ngaphambi kokuyeka noma yimuphi umuthi owuthathayo. Amazinga e-prolactin avame ukubuyela esimweni esijwayelekile zingakapheli izinsuku ezintathu kuya kwezine zokuyeka umuthi.

• Ezinye izimo zempilo : Ngisho noma ingenayo i-prolactinoma, ezinye izimo zingabangela amazinga aphezulu e-prolactin. Lezi zimo zifaka:
• Ukulimala odongeni lwesifuba (isib. ukuphuka kwezimbambo)
• Isifo sezinso esingamahlalakhona
• Isifo sesibindi esingamahlalakhona
• Isifo sikaCushing
• I-Hypothyroidism (i-thyroid engasebenzi kahle)
• I-Herpes zoster (ama-shingles), ikakhulukazi uma kuvela amabhamuza/amabala esifubeni
• I-Polycystic ovary syndrome (i-PCOS)

Kuthiwani uma ungasitholi isizathu?

Ngezinye izikhathi odokotela abakwazi ukuthola imbangela yalokhu. Uma kunjalo, kubizwa ngokuthi "idiopathic hyperprolactinemia." Lokhu kuvame ukuphela ngaphandle kokwelashwa zingakapheli izinyanga ezimbalwa.

Yiziphi izinto ezibangela ingozi?

Isici esiyingozi kuphela esaziwayo se-hyperprolactinemia yisimo esibizwa ngokuthi i-Multiple endocrine neoplasia (MEN) uhlobo 1 (MEN1). I-MEN1 yisimo esizuzwa njengefa esingaholela ekuthuthukisweni kwe-prolactinoma.

Uma othile emndenini wakho (umfowethu, udadewethu, umzali) ene-'MEN1', kuwumqondo omuhle ukuthola ukuhlolwa kofuzo. Lokhu kungasiza ekutholeni i-'(Prolactinoma)' kusenesikhathi.

Ukubona kanjani lokhu ngqo?

Uma unalezi zimpawu, into yokuqala udokotela angayenza ukuhlola igazi le-prolactin (PRL).

Uma imiphumela iqinisekisa ukuthi une-hyperprolactinemia, isinyathelo esilandelayo ukuthola imbangela. Udokotela wakho angase akucele ukuhlolwa kwegazi okwengeziwe kanye nokuhlolwa kwesithombe (njengokuskena kwe-MRI).

Yiziphi izindlela zokwelapha?

Ukwelashwa kuncike embangela. Uma amazinga akho e-prolactin ephezulu kodwa izimpawu zakho zincane, ungase ungadingi ukwelashwa.

Ukwelashwa kwe-prolactinoma

Lena imbangela evame kakhulu. Ngakho-ke kunezindlela eziningana zokuyelapha:

• Imithi : Ama-dopamine agonists alawula amazinga akho e-prolactin. Le mithi iyasebenza kakhulu ekunciphiseni izimila ze-prolactinoma. Lena yindlela yokwelapha evame ukusetshenziswa kakhulu ye-prolactinoma.
• Ukuhlinzwa : Uma i-prolactinoma inganciphi ngemithi, kungase kudingeke ukuhlinzwa ukuze isuswe.
• Ukwelashwa ngemisebe : Lena yindlela yesithathu engasetshenziswa kakhulu. Isetshenziswa kuphela uma ezinye izindlela zingaphumeleli.

Uma kungenxa yomuthi...

Uma kutholakala ukuthi amazinga akho e-prolactin aphezulu ngenxa yemithi oyiphuzayo, udokotela wakho uzokunikeza imithi ehlukile engeke ibe nomthelela omkhulu emazingeni akho e-prolactin.

Angakanani amathuba okululama?

I-Hyperprolactinemia ivame ukuba ngcono ngoba imbangela eyinhloko yelashwa ngempumelelo.

Nakuba lokhu kungasongeli impilo, kungabangela izinkinga ezifana nokungazali kanye nokujikeleza kokuya esikhathini okungajwayelekile, ngakho-ke kubaluleke kakhulu ukufuna ukwelashwa uma unalesi simo.

Imibuzo okufanele uyibuze udokotela wakho

Uma une-hyperprolactinemia, kungaba usizo ukubuza udokotela wakho le mibuzo:

• Kungani lokhu kwenzeke kimi?
• Yiziphi izivivinyo okudingeka ngizenze?
• Yiziphi izindlela zokwelapha enginazo?
• Yiziphi izinzuzo kanye nokungalungi kwenketho ngayinye yokwelashwa?
• Ingabe inkinga yami yokungazali izoxazululwa ngemva kwalokhu kwelashwa?

I-Hyperprolactinemia ingathinta ikhwalithi yempilo yakho futhi iphazamise ikhono lakho lokuba nezingane. Kodwa into engcono kakhulu ukuthi ingelashwa kahle. Uma unezimpawu zalesi simo, qiniseka ukuthi ubona udokotela. Ngemuva kwalokho ukuhlolwa kwegazi okulula kungahlola amazinga akho e-prolactin.

Okokugcina, okufanele ukukhumbule

Bheka, i-hyperprolactinemia ukwanda kwe-hormone prolactin emizimbeni yethu. Lokhu kungabangela izinkinga ezifana nobunzima bokukhulelwa izingane, ukwehla kwesifiso sobulili, ukungahambi kahle komjikelezo wokuya esikhathini kwabesifazane, kanye nokungabi namandla ocansi kwabesilisa .

Imbangela eyinhloko yalokhu isimila esibizwa ngokuthi ``Prolactinoma`` esikhula endlaleni ye-pituitary. Lesi simo singabangelwa nayimithi ethile kanye nezinye izifo .

Ungakhathazeki! Kunezindlela zokwelapha ezinhle zalokhu. Uma unalezi zimpawu, kungcono ukubona udokotela ngokushesha okukhulu. Ngemuva kwalokho ungathola imbangela eqondile bese uqala ukwelashwa okukufanele kakhulu. Kubaluleke kakhulu ukunakekela impilo yakho.

I- Prolactin, i-Hyperprolactinemia, i-pituitary gland, ukungalingani kwama-hormone, ukungazali, i-Galactorrhea, i-Prolactinoma