Ake sifunde ngokuhlolwa kwegazi kwe-Thyroxine (T4), okukutshela ngamazinga akho e-thyroid hormone.

Ingabe ngezinye izikhathi uzizwa ukhathele kakhulu ngaphandle kwesizathu? Noma, ingabe wehlisa isisindo kungakhathaliseki ukuthi udla okungakanani, noma uthola isisindo ngisho nalapho udla kancane? Mhlawumbe awukwazi ukubekezelela umkhuhlane. Ngemuva kwalezi zinto, kungase kube nenkinga ngesitho esincane kodwa esibaluleke kakhulu emzimbeni wethu. Leso yi-thyroid gland. Ngakho-ke namuhla sikhuluma ngokuhlolwa kwegazi kwe-thyroxine (T4), okusitshela ulwazi olubalulekile mayelana nokusebenza kwe-thyroid gland.

Kalula nje, iyini i-thyroxine (T4)?

I-Thyroxine (T4) iyi-hormone enkulu ekhiqizwa yi -thyroid gland , isitho esimise okwebhabhathane esitholakala ngaphambili entanyeni yethu, ikakhulukazi eduze komphimbo. Le gland encane ilawula izinqubo eziningi ezibalulekile emzimbeni wethu.

• Izinga esiguqula ngalo ukudla esikudlayo kube amandla ( Metabolism )
• Isivinini ukudla okudlula ngaso ohlelweni lokugaya ukudla
• Isilinganiso senhliziyo yethu kanye nokushisa komzimba
• Ukuthuthukiswa kobuchopho ezinganeni ezincane
• Indlela imisipha efinyela ngayo
• Izinga lokufa kwamaseli emzimbeni kanye nokwakheka kwamaseli amasha

I-T4 yi-hormone eyinhloko ekhiqizwa yi-thyroid gland. Kodwa-ke, lokhu akusebenzi ngqo (ifomu elingasebenzi). Ukuze izitho zomzimba wethu ziyisebenzise, ​​i-hormone ye-T4 kumele iguqulwe ibe yi-hormone esebenzayo i-triiodothyronine (T3) . Amaseli ezitho ezifana nesibindi sethu, izinso, kanye nobuchopho anekhono lokuguqula le-T4 ibe yi-T3.

Dokotela, kungani ungicela ukuthi ngenze ukuhlolwa kwe-T4?

Kunezizathu eziningana zokuthi kungani udokotela wakho engase ancome ukuhlolwa kwegazi kwe-T4.

• Ukuhlonza izifo ze-thyroid : Lokhu kuhlolwa kubalulekile ekuhlonzeni izimo ezifana ne-hypothyroidism noma i-hyperthyroidism kanye nokuqapha isimo ngesikhathi sokwelashwa.
• Thola izinkinga ngendlala ye-pituitary: Indlala ye-pituitary ebuchosheni bethu ikhiqiza i-hormone ebizwa ngokuthi i-TSH (i-Thyroid-Stimulating Hormone). Le hormone ye-TSH itshela indlala ye-thyroid ukuthi ingakanani i-T4 ne-T3 okufanele iyenze. Ngakho-ke, ukuhlolwa kwe-T4 kusiza futhi ukubona ukuthi kunenkinga ngendlala ye-pituitary.
• Ezinye izimbangela: Ezinye ezifana ne-TSH noma i-T3Uma kukhona ukungahambi kahle ekuhlolweni kwe-thyroid, uma kukhona iqhubu endlaleni ye-thyroid, uma indlala ivuvukele, noma uma unenkinga yokukhulelwa umntwana, ungase ucelwe ukuthi wenze isivivinyo se-T4 ukuze kutholakale ukuthi i-thyroid yakho isebenza kanjani kahle.

Manje ake sibone ukuthi yiziphi izimpawu ezingaba khona uma amazinga e-T4 ephansi futhi ephezulu.

Isimo se-thyroid	Izimpawu ezivame ukubonakala
Amazinga e-T4 aphansi (i-Hypothyroidism) Ukunciphisa ukusebenza komzimba	Ukucindezeleka okukhulu, ukulahlekelwa inkumbulo nokunaka, ukuvuvukala okuzungeze amehlo, ukulahlekelwa izinwele, ukuvuvukala kwendlala yegilo (i-goiter), ukukhathala okukhulu, ukungakwazi ukubekezelela umkhuhlane, ukukhuluphala, ukulahlekelwa yisifiso sokudla, isikhumba esomile nesibandayo, ukushaya kwenhliziyo okuhamba kancane, ubunzima bokuphefumula, ukuqunjelwa, imijikelezo yokuya esikhathini engajwayelekile kwabesifazane.
Amazinga e-T4 akhuphukile (i-Hyperthyroidism) Ukusebenza komzimba okusheshayo	Ukucasuka njalo nokungahlaliseki, ukuqwasha, amehlo avuvukele (isifo samehlo sikaGraves), ukwehla kwesisindo, indlala enkulu, ukungabekezelelani nokushisa, ukujuluka ngokweqile, ukuthuthumela kweminwe, ikhanda, noma ubuso, ukushaya kwenhliziyo okusheshayo noma okushaya ngamandla, umfutho wegazi ophakeme, isifo sohudo.

Izinto okufanele uzazi ngokuhlolwa kwegazi le-T4

Yini i-Free T4 kanye ne-Bound T4?

Kunezinhlobo ezimbili ze-hormone ye-T4 emzimbeni wethu.

• I-T4 yamahhala: Lena yi-T4 ejikeleza ngokukhululeka egazini, ingaboshelwe kunoma yini. Lena yi-T4 engangena emaseli futhi isetshenziswe nganoma yisiphi isikhathi.
• I-T4 eboshiwe: Lezi ziboshiwe kumaprotheni futhi zihamba egazini. Lawa maprotheni asiza i-hormone ye-T4 ukuthi ithuthwe ngokuphephile iye lapho idingeka khona, ngaphandle kokumuncwa amanye amangqamuzana endleleni. Iningi le-T4 emzimbeni wethu liboshiwe ku-T4.

Odokotela bavame ukubheka izinga le-Free T4 ngoba liyinani le-T4 umzimba ongalisebenzisa, futhi linikeza umbono omuhle kakhulu wokuthi i-thyroid isebenza kahle kangakanani.

Izinto okufanele uzicabangele ngaphambi kokuhlolwa

Ngaphambi kokuhlolwa kwegazi, kubalulekile ukutshela udokotela wakho nganoma yimiphi imithi, amavithamini, noma izithasiselo ozithathayo. Eminye imithi, njengemithi yokulwa nokuquleka, imithi yenhliziyo, kanye namaphilisi okulawula ukuzalwa, ingathinta imiphumela yakho ye-T4. Ikakhulukazi uma uthatha isithasiselo se -biotin , singenza amazinga akho e-T4 abonakale ephakeme kunalokho ayikho ngempela. Lokhu kungabangela udokotela wakho ukuthi aphuthelwe inkinga ye-thyroid. Tshela nodokotela wakho uma ukhulelwe noma unezinye izimo zezokwelapha, njengesifo sezinso.

Ingabe kukhona izingozi zokuhlolwa kwegazi le-T4?

Lokhu ukuhlolwa okuvamile, njenganoma yikuphi ukuhlolwa kwegazi. Umuntu oqeqeshwe usebenzisa inalithi encane ukuthatha inani elincane legazi emthanjeni osengalweni yakho bese efaka i-patch endaweni. Izingozi zincane kakhulu, kodwa ngezinye izikhathi okulandelayo kungenzeka:

• Ubuhlungu obuncane lapho inaliti ifakiwe khona.
• Ukopha okuncane
• Ukuphuka (igazi lihlangana ngaphansi kwesikhumba)
• Uma unganakekeli ukuhlanzeka, ungathola ukutheleleka.
• Isiyezi noma ukuquleka

Ukuqonda imiphumela yokuhlolwa kwe-T4

Amabanga ajwayelekile okuhlolwa kwe-Free T4 angahluka kancane kuye ngobudala, ubulili, kanye nelebhu eyenza ukuhlolwa. Kodwa-ke, ngokuvamile, amanani ajwayelekile alandelayo: Into ebaluleke kakhulu ukuthi udokotela wakho kuphela ongachaza amanani akulo mbiko ngendlela evumelana nesimo sakho. Ngakho-ke, qiniseka ukuthi uyawuthatha umbiko bese ubona udokotela wakho.

Izimbangela zamazinga aphansi e-T4 (i-Hypothyroidism)

• I-Hashimoto's thyroiditis: Lesi yisifo esibangelwa ukuzivikela komzimba. Lokhu kusho ukuthi amasosha ethu omzimba ahlasela i-thyroid gland ngephutha.
• Ukuntuleka kwe-iodine ekudleni.
• Izifo ezithathelwanayo zesikhathi esifushane.
• Ukungondleki kahle.
• Eminye imithi.

Izimbangela zokwanda kwamazinga e-T4 (i-Hyperthyroidism)

• Isifo sikaGraves: Lesi futhi yisifo sokuzivikela komzimba.
• I-iodine eningi ekudleni.
• Amaqhubu angewona umdlavuza (izimila/amaqhubu angewona awemvelo) endlaleni yegilo.
• Ukuvuvukala kwendlala yegilo (i-Goiter).
• Ukwandisa umthamo wemithi ye-thyroid hormone esetshenziselwa ukwelashwa.

Ukuhlolwa okwengeziwe

Nakuba ukuhlolwa kwe-T4 kungabonisa ukuthi kunenkinga nge-thyroid gland yakho, akukwazi ukukutshela ngqo ukuthi yini ebangela lokho. Ngakho-ke, uma izinga lakho le-T4 lingajwayelekile, udokotela wakho cishe uzoyala ukuhlolwa okwengeziwe ukuthola imbangela.

• Ukuhlolwa kwegazi le-TSH: Lokhu kuvame ukuba ukuhlolwa kokuqala okwenziwayo. Amazinga e-TSH ne-T4 ahlobene ngqo.
• Ukuhlolwa kwegazi kwe-T3 kwamahhala: Kuhlola izinga lenye i-hormone eyinhloko eyenziwe yi-thyroid gland.
• Ukuhlolwa kwama-antibodies e-thyroid: Hlola isifo esifana nesikaHashimoto noma sikaGraves.
• Isithombe sokuthathwa kwe-iodine emisebeni: Bona indlela i-thyroid gland emunca ngayo i-iodine.

I-thyroid, ukuhlolwa kwe-T4, i-Thyroxine, i-Hypothyroidism, i-Hypothyroidism, i-Hypothyroidism, izimpawu ze-thyroid, Ukuhlolwa kwegazi, i-TSH